The fibrillar organization is crucial for the mechanics of osteonal bone and for its anisotropy. Different collagen fiber orientation (CFO) patterns are observed in bone and correlated to the main local loading, leading to the hypothesis that the fibers are preferentially aligned to bear specific loading types. A heterogeneous distribution of osteon morphotypes (OMs) is noticed in long bones, although the relationship between the OM spatial distribution and the local predominant loading is still unclear. This study aims to shed light on the reasons why Nature uses specific OMs in diverse stress‐dominated regions. A multimodal approach is adopted, including collagen fiber orientation mapping, numerical modeling of different OMs under tensile and compressive loading, and 3D‐printing of OM‐inspired samples, to unravel the relationship between different OMs and their mechanical behavior. Simulation results suggest a better performance of the vertical OM (VOM) under tensile loading and of the twisted OM (TOM) under compression, confirming earlier hypotheses. The outcomes of mechanical testing, conducted on 3D‐printed samples, highlight a possible buckling‐induced failure of fibers with preferential vertical orientation and provide evidence that OMs are stress‐tailored, opening new venues for the design of stress‐tuned bioinspired composites.

This study aims to explore the relationship between transformational leadership and organizational commitment in multinational companies (MNCs) in Morocco.,The study used a sample size of 256 employees to attain results regarding a relationship between transformational leadership and organizational commitment. Proposed hypotheses are tested through regression analysis.,Findings show a relationship between transformational leadership and organizational commitment. Organisations use different leadership styles and thus act differently. However, tranformational leadership shows its importance in leading organisations who aim to be constantly committed.,To the authors’ knowledge, this is the first research in North Africa that investigates the level of transformational leadership and organizational commitment in MNCs.

Ovim radom ispituje se da li i na koji način politički poredak u Bosni i Hercegovini determiniran logikom etnopolitike sadrži i producira subverzivni potencijal za vlastitu negaciju. Ideja se postepeno javljala u kontekstu različitih protesta u proteklih pet godina, ali se kao naučno pitanje ozbiljnije oblikovalo tek stapanjem protesta “Pravda za Dženana” i “Pravda za Davida” 2018. godine. Kroz proteste se od jedinstvenog matičnog broja i zdravstva preko radničkih prava i demobilisanih boraca kao politiziranih tijela par excellence pa sve do institucionalizirane instrumentalizacije smrti uočava izražena biopolitička dimenzija sa potpisom etnodeterminizma. Politološkim čitanjem odnosa između kontrahegemonijskih narativa odozdo i njihove sve vidljivije kriminalizacije odozdo, autor problematizira kako ono što se ovdje naziva biopolitikom etnodeterminizma producira narativ otpora kao mogućnost koja osvjetljavanjem naličja samog sistema dovodi u pitanje osnovu njegove legitimacije.

Abstract Purpose: To investigate contemporary results of percutaneous transluminal renal angioplasty (PTRA). Materials and Methods: A multicentre retrospective study analysing all patients treated with PTRA for primary symptomatic renal artery stenosis (RAS) between 2010 and 2013 at four tertiary centres. Procedures during the preceding four years were counted to evaluate for change in PTRA frequency. Results: The number of PTRA procedures decreased by approximately 50% from 2006 to 2013. Patients treated in the post-ASTRAL period (n = 224) had a significant reduction in mean systolic pressure (168 to 146 mmHg, p < 0.01), diastolic pressure (84 to 76 mmHg, p < 0.01), number of anti-hypertensive drugs (3.54 to 3.05, p < 0.01), and anti-hypertensive treatment index (21.75 to 16.92, p < 0.01) compared to before PTRA. These improvements were maintained at one year and at the last clinical evaluation after a mean follow-up of 4.31 years. Renal function increased transiently without sustained improvement, or deterioration, during later follow-up. Thirteen patients (5.8%) eventually required dialysis, nine of these had eGFR <20 ml/min/1.73 m2 before PTRA. There was no difference in outcomes between subgroups differentiated by different indications for PTRA. Conclusion: The frequency of PTRA has decreased, indicating a higher threshold for invasive treatment of RAS in recent years. The reduction in blood pressures, the reduced need for anti-hypertensive medication, and stabilization of renal function over time suggest a clinical benefit for most patients who are now being treated with PTRA.

COVID-19 pandemic is plaguing the world and representing the most significant stress test for many national healthcare systems and services, since their foundation. The supply-chain disruption and the unprecedented request for intensive care unit (ICU) beds have created in Europe conditions typical of low-resources settings. This generated a remarkable race to find solutions for the prevention, treatment and management of this disease which is involving a large amount of people. Every day, new Do-It-Yourself (DIY) solutions regarding personal protective equipment and medical devices populate social media feeds. Many companies (e.g., automotive or textile) are converting their traditional production to manufacture the most needed equipment (e.g., respirators, face shields, ventilators etc.). In this chaotic scenario, policy makers, international and national standards bodies, along with the World Health Organization (WHO) and scientific societies are making a joint effort to increase global awareness and knowledge about the importance of respecting the relevant requirements to guarantee appropriate quality and safety for patients and healthcare workers. Nonetheless, ordinary procedures for testing and certification are currently questioned and empowered with fast-track pathways in order to speed-up the deployment of new solutions for COVID-19. This paper shares critical reflections on the current regulatory framework for the certification of personal protective equipment. We hope that these reflections may help readers in navigating the framework of regulations, norms and international standards relevant for key personal protective equipment, sharing a subset of tests that should be deemed essential even in a period of crisis.

COVID-19 pandemic is plaguing the world and representing the most significant stress test for many national healthcare systems and services, since their foundation. The supply-chain disruption and the unprecedented request for intensive care unit (ICU) beds have created in Europe conditions typical of low-resources settings. This generated a remarkable race to find solutions for the prevention, treatment and management of this disease which is involving a large amount of people. Every day, new Do-It-Yourself (DIY) solutions regarding personal protective equipment and medical devices populate social media feeds. Many companies (e.g., automotive or textile) are converting their traditional production to manufacture the most needed equipment (e.g., respirators, face shields, ventilators etc.). In this chaotic scenario, policy makers, international and national standards bodies, along with the World Health Organization (WHO) and scientific societies are making a joint effort to increase global awareness and knowledge about the importance of respecting the relevant requirements to guarantee appropriate quality and safety for patients and healthcare workers. Nonetheless, ordinary procedures for testing and certification are currently questioned and empowered with fast-track pathways in order to speed-up the deployment of new solutions for COVID-19. This paper shares critical reflections on the current regulatory framework for the certification of personal protective equipment. We hope that these reflections may help readers in navigating the framework of regulations, norms and international standards relevant for key personal protective equipment, sharing a subset of tests that should be deemed essential even in a period of crisis.

The need for the exact overview of technology, which is the target for some purposes is often very crucial. Patent databases provide nowadays very suitable source of data and information which can be further analyzed. Global overview is thus possible to provide for any kind of technology. Smart Furniture is a very used term recently, which is related to current trends such as digitization, smart city or internet of things. Within these phenomena, Smart Furniture is used in different contexts, and so its concept is not clarified. The aim of the article is to show the technology analysis of Smart Furniture based on the patent data analysis and literature analysis by clustering and visualization. The definition of Smart Furniture was recently provided in literature based on previous research which was undertaken based on searching in scientific and patent databases. Thus, the term is defined by its technical properties and parameters. This definition is put into the context of actual trends of patents content with selected future trends. A patent analysis was undertaken between 20 October 2019 and 09 November 2019, while the Web of Science database was included, which was searched by keywords that included the phrase "Smart Furniture" and variants. Patent searching was performed in the PatentInspiration database. In total 31 articles from scientific database and 491 patent applications were examined against strict criteria containing meaningful definitions of Smart Furniture. Based on the analysis of key technologies and properties, clustering of results and their further analysis, it was found that the concept of smart furniture is specific to the following components: intelligent system, controller operated with user's data and energy sources, sensors and actuators.

We present a simple method to quickly explore C-spaces of robotic manipulators and thus facilitate path planning. The method is based on a novel geometrical structure called generalized bur. It is a star-like tree, rooted at a given point in free C-space, with an arbitrary number of guaranteed collision-free edges computed using distance information from the workspace and simple forward kinematics. Generalized bur captures large portions of free C-space, enabling accelerated exploration. The workspace is assumed to be decomposable into a finite set of (possibly overlapping) convex obstacles. When plugged in a suitable RRT-like planning algorithm, generalized burs enable significant performance improvements, while at the same time enabling exact collision-free paths.

Abstract This paper analyses the inefficiency of social services targeting in the Federation of Bosnia and Herzegovina (FB&H). Using official statistics microdata of the Household Budget Survey 2015, three models of social minimum in FB&H were constructed: extreme and general poverty, and the model with multidimensional poverty aspects. The analysis of features of poor household categories showed that the most vulnerable residents of FB&H are not beneficiaries of permanent financial assistance. The reason for such an inefficient targeting was recognized in the Federal Law on Principles of Social Care, Care for the War-Disabled Civilians and Care for Families with Children that stipulates that only persons and families that (cumulatively): are incapable for work, have insufficient income, and there are no family members who are legally obligated to support them. The results indicated a high inconsistency in the legal criteria for qualification, and also in the amounts of permanent social assistance among cantons. The Proxy Means Test (PMT) Model is offered as one of the possible solutions for the improvement of social services targeting in FB&H. Given the importance of efficiency of targeting in social services, the research results could be useful, for both, vulnerable segments of the society and federal and cantonal ministries of labour and social affairs, in the process of targeting the households qualified for social support programmes.