Students’ learning outcomes in physics are significantly affected by the quality of outside-of-classroom learning experiences. A rich source of these experiences may be the physics homework. In this study, the effects of technologically-rich physics homework were evaluated. To that end a pretest-posttest experimental design has been used. 67 first-year students from the First Bosniak Gymnasium were randomly assigned to one of the three homework approaches. In the control group students received conventional homework about work and energy. Within the simulation-based approach students were expected to interact with simulations to investigate work and energy phenomena, whereas in the video-based approach students learned by analyzing a video in which the teacher interacted with the same simulations as mentioned above. Based on analysis of covariance we could find that the between-group differences on the conceptual posttest were not statistically significant, F(2, 47)=0.59, p=0.56. At the same time, students who learned by interacting with simulations expressed significantly more positive attitudes towards homework, compared to students from the video-based group (mean difference=1.88, p=0.038), as well as compared to students from the conventional group (mean difference=2.02, p=0.03). Simulation-based physics homework may be a powerful tool for helping the students to reach important affective learning outcomes.

Background: Myocardial surgical revascularization in patients with low left ventricular ejection fraction (LVEF) is accompanied by a high rate of morbidity and mortality. Objective: The aim of this study was to investigate and eliminate the reasons for the most common perioperative and postoperative complications. Methods: A total of 64 were analyzed. of patients during 2019 who underwent coronary artery bypass grafting (CABG), average age 61.29±9.12 years. Results: Out of the total number of operated patients, there were 16 women and 48 men. Patients were divided into two groups. The first group consisted of patients who underwent surgery with the use of cardiopulmonary bypass (cCABG-CPB) and the second group those who underwent surgery without the use of cardiopulmonary bypass (OPCAB). In 41 patients, myocardial infarction was previously recorded. Critical stenosis of the main trunk of the left coronary artery was present in 14 patients. The incidence of postoperative complications was higher in the cCABG-CPB 16/10 group (p0.030). Conclusion: In our study, we confirmed that myocardial revascularization is justified, especially in the case of multivessel coronary disease. In the long term, it significantly improves the systolic function of the left ventricle, and thus and quality and length of life.

Augmented reality (AR) makes it possible to overlay digital content onto our view of real-world phenomena. This potentially facilitates learning of physics by visualizing connections between concrete physics phenomena and abstract physics formalism. Here we present a part of our systematic review of earlier research on the use of augmented reality (AR) in school and university teaching physics topics. Our systematic review includes 60 articles published between 2012 and 2020, indexed in the Scopus and Eric databases. We analyzed the technological properties of AR for different content areas of physics as well as various methodological aspects of earlier AR research in physics education (e.g., educational level of participants, sample size, and research design). It has been shown that AR becomes increasingly popular in the physics education research community.

In recent years of social distance due to the pandemic, augmented reality (AR) with its ability to overlay real phenomena with digital content has become even more attractive for making physics experiments accessible to every student. Therefore, we have recently developed an AR application for Android mobile devices that allows users to study how the gravitational force between two spherical bodies depends on their masses and their mutual distance. The purpose of this study is to investigate students' experience of using this application. To that end, 85 undergraduate students from the University of Zagreb were asked to use our AR application for completing a task related to the concept of gravity. Thereafter, they were administered five open-ended and 30 close-ended questions from three different questionnaires: System Usability Scale (SUS), User Experience (UX), and Handheld Augmented Reality Usability Scale (HARUS). Analysis of students’ responses revealed that students perceived the application as easy to use, consistent, self-explanatory, and enjoyable. Valuable feedback was provided on possible improvements to the application.

Abstract Food conveys the sense of a place, and it encapsulates both the natural and cultural meanings that locals attach to their culinary heritages. Food tourism contributes to the sustainable development of destinations because food-based activities are part of sustainable tourism practices. Sarajevo is becoming an increasingly popular gastronomic destination. The purpose of this research is to analyse the food image of the city of Sarajevo, Bosnia and Herzegovina, as a relevant issue for food tourism sustainable development in urban environments. To achieve it, this resear ch understands restaurants as a food tourism attraction. To analyse how a destination promotes food identity, this article draws from a content analysis of 16 menus from restaurants located in the four municipalities of the city of Sarajevo. Results rev eal to what extent local restaurants offer menus based on local foods and drinks that represent Bosnian-Herzegovinian cuisine. In particul ar, the research contributes to understanding food tourism in cities, and how restaurants can be crucial in developing and promoting sustainable tourism.

Bckground: Aerobic vaginitis is an imbalance of the vaginal flora and the main characteristic is an abnormal vaginal flora that contains aerobic and intestinal pathogens with varying degrees of vaginal inflammation. The frequency of AV varies from 12% to 23.7% in symptomatic women who are not pregnant and 4 to 8% during pregnancy and has an increased risk for sexually transmitted diseases (STI). The causative agents of AV are: Enterococcus faecalis (E. faecalis), Esherichia coli, group B streptococcus and Staphylococcus aureus. Objective: The aim of this review was to present the most important features of aerobic vaginitis regarding description of this frequent clinical problems within population in Bosnia and Herzegovina and also worlfwide. Methods: Author analized aerobic vaginitis based on scientific literature by searching published papers in important indexed databases. Results and Discussion: The most frequently isolated AV pathogen is E. faecalis in about 31%. New works indicate the presence of the HPV 16 gene and genome in E. faecalis in the biopsied material of cervical cancer, as well as the ability that HPV 16 genes can be translated and transcribed in these bacteria, and that the HPV gene can form viral particles in these bacteria leads to certain connection that can be a risk factor in the progression of cervical lesions to cancer. A decrease in the number of lactobacilli in the vaginal secretion reduces the defense ability and changes the pH value of the vaginal environment, which favors the development of bacterial inflammation. AV positive for E. faecalis leads to a change in the pH value of the vaginal environment above 5, and the increased pH value of the vaginal environment in HPV positive women can be an association for cervical intraepithelial lesion (CIN). A dominant pathogen in AV such as E. faecalis can reduce the protective effect of lactobacilli by causing inflammation, as well as an increase in IL-6, IL-8 and TNF, increasing the risk of HPV 16 infection resulting in CIN and cervical cancer. In cervical cancer research, the presence of genes and genomes (except E1) of human papillomavirus (HPV) type 16 was found in bacteria such as: E. faecalis and Staphylococcus aureus from cervical cancer biopsies. Intensive treatment of AV could be a very important factor in preventing the onset of precancerous lesions and cervical cancer. The recommended treatment of AV includes a combination of therapy such as: antibacterial (antiseptic and antibiotic), hormonal, non-steroidal anti-inflammatory and/or probiotics, which can be prescribed in the form of local or systemic therapy. Conclusion: There is no generally accepted clinical strategy for the treatment of AV caused by E. faecalis. Most authors suggest that therapy be based on microscopic or microbiological findings using a topical antibiotic for the infectious agent, a topical steroid to reduce inflammation, and estrogen to treat atrophy.

Abstract This paper investigated the opportunities for public sector improvement by digitalization Financial Management and Control (FMC) system in the Western Balkans (WB) countries. Optimizing business processes within public sector through the digitalization of the FMC system offers opportunities for public sector improvement. The idea is to analyze the existing legal solutions on FMC system in the WB countries and evaluate the current level of digitalization of the system to find the abilities for improvement FMC. The data obtained through an interview with management persons in the Ministry of Finance of the WB Countries and key experts who worked on behalf of the EU as expert consultants on EU-funded projects. Also, we use secondary data collected by exploring literature and OECD reports. Since the database is limited, we use descriptive statistics to analyze the data and the case-study method. The digitalization of the entire system presented only at the entity and state level in Bosnia and Herzegovina. The research showed that the development of a quality FMC system can be enabled by the digitalization of the entire system. The main contribution of this paper is its focus on digitalization of FMC system, since there is limited research paper on this subject.

A study on 51 SNPs belonging to 29 genes related to heat stress was carried out in 720 sheep from 17 different breeds adapted to different climates from Hungary, Bosnia and Herzegovina, Morocco and Romania, using Kompetitive Allele-Specific Polymerase Chain Reaction. Genotype frequency and the Hardy–Weinberg equilibrium were calculated, followed by a clustering using the Principal Component Analysis. We analyzed the polymorphisms in the following genes analyzed: HSPA12A,HSP90AA1,IL33,DIO2,BTNL2,CSN2,ABCG1,CSN1S1,GHR,HSPA8,STAT3, and HCRT. We emphasized on HSPA12A and HSPA8 genes as they were successfully genotyped in all studied flocks in which genotype frequency patterns were identified. Contrary to previous findings, the A allele for HSPA8 SNP was not observed in the heat tolerant breeds, being found exclusively in cold-tolerant breeds. The principal component analysis could not clearly differentiate the breeds, while plot concentration was slightly varied among the three groups, with HSP90AA1 and IL33 SNPs’ loading values significantly contributing to PC1 and PC2. We confirmed previous works that the HSPA12A,HSPA8,HSP90AA1 and IL33 SNPs are potential candidate markers for thermotolerance adaptation in sheep. This research contributes to the genetic variability of SNPs for thermotolerance adaptability in sheep.

In the hilly Balkans, a folk proverb has been circulating for a long time, „It is most difficult to be a prophet in one‘s own village“, which reflects the age-old mistrust of the population towards new ideas. This is not surprising in the least, because since the written history of the peoples of the Balkans has existed, a continuous series of conquerors and local rulers who subjugated the common folks and imposed their world view can be traced. Nevertheless, from time to time, people with great strength appear who not only break the shackles imposed by the powerful, but through their actions find a way to the souls of their compatriots and gain their unreserved trust. One of such spontaneous creators is professor Izet Mašić, who achieved a miracle of medical publishing in his Sarajevo and Bosnia and Herzegovina and traced the path of medical science. There may be thousands of medical journals in the world, more or less reputable, and researchers from the Balkans can publish their work in them, but only domestic medical journals can initiate and direct domestic medical research, and educate young researchers in the right way. Professor Mašić made it possible for authors from Bosnia and Herzegovina and other Balkan countries to present their results to the world and receive an incentive from impartial experts to continue their work and progress more and more by editing and publishing three domestic journals at once, which are visible in the most important world bases,. The progress in research then translated into improving medical practice and health care of the population. The following details from Professor Mašić‘s biography tell us how this miracle happened. This year, academician Izet Mašić, Editor-in-Chief of a few biomedical journals, including Acta Informatica Medica journal, celebrates his 70th birthday and also 45 years of his academic and scientific work.

Background: Thromboembolic complications are a frequent occurrence during COVID-19. This report presents a patient with signs of subclavian steal syndrome (SSS) caused by a thrombus in the initial part of the right subclavian artery. Pathological occlusive changes, such as thrombosis, are four times more common on the left subclavian. Thrombosis of the subclavian artery occurs in about 1% of the population, but atherosclerotic changes are common and usually asymptomatic. Objective: The aim of this report is to present a patient with signs of subclavian steal syndrome (SSS) caused by a thrombus in the initial part of the right subclavian artery associated with symptoms of COVID-19. Case report: A 56-year-old female patient presented with tremor, numbness and prickling in the right hand, tinnitus, blurred vision, vertigo, syncope, trismus and headaches. The formation of a thrombus caused neurological symptoms in the right hand with a stronger pronounced tremor, headache and syncopal episodes. Routine CT with angiography did not reveal significant subocclusions of the neck arteries or significant ischemic changes in the brain. The patient was treated as Parkinsonismus (disease) with syncopal and collapsing episodes. Due to worsening subjective complaints, CT angiography of the neck and head blood vessels was repeated with iterative 3D reconstruction. The examination, as mentioned above, revealed atherosclerotic changes with thrombosis and stronger subocclusion of the right subclavian artery (RSA) proximal to the origin of the arteria vertebralis. Both vertebral arteries, as well as arteria basilaris, had a normal appearance. During physical exertion of the right arm doppler examination of neck blood vessels revealed the presence of reverse blood flow in the right vertebral artery. Haematological tests and high D-dimer also confirmed the diagnosis. After anticoagulant therapy, the thrombotic mass on the mural calcified RSA plaque disappeared. With the reduced physical strain on the right hand and a lifestyle change, syncopal conditions and headaches stopped. There was a reduction in tremors and tingling in the right hand as well. Conclusion: We reported a case of subclavian steal syndrome caused by thrombosis associated with OVID-19. Thromboembolic complications are common in the course of this disease. The diagnosis was confirmed with advanced diagnostic tools (CTA with 3D reconstruction), laboratory tests (D-dimer) and doppler ultrasound. When routine CT angiography is not completely clear, 3D reconstruction is necessary.

Mycoplasma ovipneumoniae, a well-established respiratory pathogen of sheep and goats, has gained increased importance recently because of its detection in wild ruminants including members of the Cervidae family. Despite its frequent isolation from apparently healthy animals, it is responsible for outbreaks of severe respiratory disease which are often linked to infections with multiple heterologous strains. Furthermore, M. ovipneumoniae is characterized by an unusually wide host range, a high degree of phenotypic, biochemical, and genomic heterogeneity, and variable and limited growth in mycoplasma media. A number of mechanisms have been proposed for its pathogenicity, including the production of hydrogen peroxide, reactive oxygen species production, and toxins. It shows wide metabolic activity in vitro, being able to utilize substrates such as glucose, pyruvate, and isopropanol; these patterns can be used to differentiate strains. Treatment of infections in the field is complicated by large variations in the susceptibility of strains to antimicrobials, with many showing high minimum inhibitory concentrations. The lack of commercially available vaccines is probably due to the high cost of developing vaccines for diseases in small ruminants not presently seen as high priority. Multiple strains found in affected sheep and goats may also hamper the development of effective vaccines. This review summarizes the current knowledge and identifies gaps in research on M. ovipneumoniae, including its epidemiology in sheep and goats, pathology and clinical presentation, infection in wild ruminants, virulence factors, metabolism, comparative genomics, genotypic variability, phenotypic variability, evolutionary mechanisms, isolation and culture, detection and identification, antimicrobial susceptibility, variations in antimicrobial susceptibility profiles, vaccines, and control.

The most distant marsquake recorded so far by the InSight seismometer occurred at an epicentral distance of 146.3 ± 6.9o, close to the western end of Valles Marineris. On the seismogram of this event, we have identified seismic wave precursors, i.e., underside reflections off a subsurface discontinuity halfway between the marsquake and the instrument, which directly constrain the crustal structure away (about 4100−4500 km) from the InSight landing site. Here we show that the Martian crust at the bounce point between the lander and the marsquake is characterized by a discontinuity at about 20 km depth, similar to the second (deeper) intra-crustal interface seen beneath the InSight landing site. We propose that this 20-km interface, first discovered beneath the lander, is not a local geological structure but likely a regional or global feature, and is consistent with a transition from porous to non-porous Martian crustal materials. The authors show that the Martian crust, ~4300 km from the InSight landing site, has a subsurface interface similar to that beneath the lander, suggesting it is a regional or global feature that may be related to the closure of pore spaces at depth.