Background/Aim: Due to the numerous beneficial effects of pomegranate that can be explained through its antioxidative effects, the aim of this study was to determine the antioxidant potential of pomegranate peel extract (PoPEx) prepared from pomegranate that was harvested in the southeast region of Herze-govina (Bosnia and Herzegovina), through in vitro and in vivo studies. Methods: In PoPEx total phenols, flavonoids, flavonols, flavan-3-ols and antho-cyanins content was determined, as well as several antioxidative assays, including 2,2 diphenyl-1-picrylhydrazyl assay (DPPH), 2,2'-azino bis(3-ethylbenzothi-azoline-6-sulphonic acid) assay (ABTS), iron (III)-2,4,6-tripyridyl-S-triazine complex assay (FRAP), reduction of copper(II) ions (CUPRAC) assay, Briggs-Rauscher oscillatory reactions, neutralisation of OH radicals and lipid peroxidation assay. In vivo studies were performed by administrating 100 mg/ kg of body weight of PoPEx to the rats by gavage for 7 days, after which the rats were euthanised and prooxidative parameters (thiobabrituric acid reactive substances-TBARS as an index of lipid peroxidation, nitrites-NO 2 , hydrogen peroxide-H 2 O 2 and superoxide anion radical O 2-) were determined in plasma, as well as antioxidative parameters (superoxide dismutase-SOD, reduced gluta-thione-GSH and catalase-CAT) in erythrocyte lysates. Results: High content of phenolic compounds was found in PoPEx, which resulted in high antioxidative potential in all in vitro tests performed. In vivo study showed that PoPEx administration caused a significant decrease in TBARS, NO 2-, as well as an increase in reduced glutathione (p < 0.05) in comparison to the control group, while H 2 O 2 and O 2 * showed a lowering trend and SOD and CAT showed an increasing trend in PoPEx group, but without statistical significance. Conclusion: PoPEx demonstrated high antioxidative capacity measured in vitro and in vivo and can be potentially used as a supplement treatment in the prevention of various inflammatory conditions.

Introduction/Objective. Unintentional injuries is a global health issue among children and adolescents. The aim of this study was to examine the characteristics of unintentional injuries divided according to different age groups and sex among the children and adolescents who have been hospitalised in public hospitals of the Republic of Srpska, Bosnia and Herzegovina. Methods. A retrospective analysis of the e-base of the Agency for certification, accreditation and health care quality improvement of the Republic of Srpska data were collected from 10 public hospitals for patients aged ?19 years, who have been hospitalised for unintentional injuries in the period of January 2018 and December 2020. Results. The study identified 1,336 patients who were hospitalised for unintentional injuries, most of whom were boys (67.4%). Falls were the most frequent cause of hospitalisation in children of all age categories (aged 1 (70.6%), 1 to 4 (59.1%), 5 to 9 (68.5%)) and adolescents aged 10-14 (64.1%), while road traffic injuries were the leading cause of hospitalisation in adolescents aged 15 to 19 (62.6%). The cause of injury for the hospitalised patients were significantly related to age (p < 0.001) and sex (p < 0.05) groups. According to the nature of the injury in relation to the area of the body, the most frequent injuries were to the head (41.1%), caused by traffic accidents and falls. Conclusion. Since falls and road traffic injuries were the leading causes of hospitalisation, preventive measures should be taken to reduce the frequency of these injuries.

Background: Dental fear and anxiety (DFA) is ubiquitous among the adult population. The anxiety component of DFA is more strongly expressed in adults, and includes a physiological and psychological component, and is more often analyzed in research. Oral-surgical interventions represent a significant source of stress for the appearance of anxiety in subjects. The research aim was to analyze the presence of anxiety with the use of the revised Corah Dental Anxiety Scale (DASR) and the Spielberger State-Trait Anxiety Inventory (STAI) in adult patients during the treatment of extraction of impacted third permanent molars by oral surgery. Material and Methods: The study included adult patients of both sexes, who were previously scheduled for oral-surgical removal of third permanent molars. Anxiety levels were assessed preoperatively and postoperatively as follows: 1st measurement (day of examination)-DASR, and STAI (X1 and X2); 2nd measurement (immediately before the intervention)-STAI (X1 and X2); 3rd measurement (day after the intervention)-STAI (X1 and X2). Results: Preoperatively, the presence of high levels of general anxiety, situational anxiety, and dental anxiety was determined. The levels were decreased before the planned surgery and were significantly reduced in the postoperative period. The STAI scale could be used to assess the presence of situational anxiety in the dental office on an equal footing with other known measuring instruments (e.g. DASR). Conclusions: Adequate therapy should be considered to prevent preoperative anxiety, which would increase the satisfaction of patients and therapists while reducing complications related to this type of intervention.

Background/Aim: Surgical removal of impacted third molars is associated with possible complications that are primarily comprehended as expected. Increase in incidence and severity of complications is directly related to the depth of impaction, and to the age of the patient as well. The aim of this research was to investigate the possible influence of the treatment duration relating to age and gender of the patients, the occurrence of pain, and the existence of previous anxiety experience connected with surgical wisdom tooth removal. Material and Methods. The study included adults of both gender indicated for surgical removal of impacted third molars. The existence of previous wisdom tooth removal experience was determined during the first examination, and the subjects' anxiety and pain levels were determined pre-, and postoperatively. Results: There were no differences concerning the place of treatment (dental office/operating room) and the duration of surgery. Younger participants showed the lowest levels of preoperative anxiety and the highest levels of postoperative anxiety, and frequently reported postoperative pain. Female participants showed higher levels of preoperative and postoperative anxiety, and also frequently reported postoperative pain. Conclusions: Anxiety and pain scores were lower when there was a previous experience with removal of impacted wisdom teeth.

We study nonlinear networked control systems (NCS), where the controller is implemented over multiple processors via an emulation-based approach. We start with a stable and centralised NCS commonly considered in the literature. Then, we show how to implement the centralised controller over multiple processors inspired by parallel computing techniques, so that stability is preserved (semi-globally and practically) under sufficiently fast computations. An example is given to illustrate the main results.

The article presents the contribution of socio-demographic, socio-economic, employment status and level of education of parents/guardians to students’ school success. The aim of this article is to discover the causes of school (un)success given the contribution of predictor variables. The predictor set of variables consists of four scales: socio-demographic status (total number of brothers, total number of sisters, marital status of parents, distance from home to school and number of members households), socio-economic status (total monthly income of parents/guardians, place to study in the house/apartment, possession of laptop/computer, constant internet access in the house/apartment and the way they come to school), employment status of parents/guardian and educated status of parent/guardian. In addition to the set of predictors, a criterion variable was used, which consists of three dimensions, namely school success at the end of the sixth, seventh and eighth grade of primary school. The results of the research confirm a statistically significant correlation between socio-demographic, socio-economic, employment status and the level of education of parents/guardians and school success of children, provided that socio-demographic status has a higher predictive power on students’ school success. It was confirmed that students have a positive attitude about the importance of the grade as well as that they perceive that their parents have the same attitude.