The beginnings of neurosurgery in Croatia date to the end of the 19th century when Teodor Wickerhauser performed the first craniotomy in the country in 1886. Exactly 60 years later, in 1946, Danko Riessner founded a separate neurosurgical ward in Zagreb and is therefore considered the founder of Croatian neurosurgery. His main scientific contribution was a paper on the shifting of brain masses, published in 1939. The Department of Neurosurgery at the University of Zagreb was founded in 1974 as one of the first institutions of its kind in Southeast Europe. Finally, the Croatian Neurosurgical Society was founded in 1992 to promote the neurosurgical profession and science at the national level. This historical vignette aimed to provide a brief chronology of the most important events and notable people in the history of Croatian neurosurgery, as well as to commemorate its founders and highlight its development from the beginning to its current state of proficiency and expertise.

Abstract The concentrations of eight heavy metals (Cd, Cr, Cu, Fe, Mn, Ni, Pb and Zn) associated with PM2.5 and PM10 in Sarajevo air, Bosnia and Herzegovina (BiH) have been studied. A total of 136 PM2.5 and PM10 samples were simultaneously collected from 21 February to 11 November 2020. Metal contents were determined by atomic absorption spectrometry, flame (FAAS) and electrothermal (ETAAS) techniques. The mean concentrations of metals in PM10 are 2.93 ng/m3 (Cd), 7.21 ng/m3 (Cr), 12.02 ng/m3 (Cu), 126 ng/m3 (Fe), 20.74 ng/m3 (Mn), 6.98 ng/m3 (Ni), 8.74 ng/m3 (Pb) and 128 ng/m3 (Zn). In PM2.5 samples the mean concentrations of Cd, Cr, Cu, Fe, Mn, Ni and Zn are 0.39, 4.06, 2.26, 110, 0.63, 1.93 and 5.28 ng/m3, respectively. Pb was not detected in PM2.5 samples. Strong correlation was obtained for metal pairs Mn-Cu in PM10 and moderate for Ni-Fe in PM2.5. The health risk assessment shows that the adult population of Sarajevo is at increased lifetime risk of experiencing cancer because of exposure to Cd concentrations in PM10.

Abstract The COVID-19 virus pandemic had an impact on all segments of life, including dally operations of companies. Companies had to adapt to market developments and change their business philosophy in order to survive in the market. This paper showed how the crisis caused by the COVID-19 virus pandemic affects the business of companies. This study aims to examine the business performance indicators (BPI) of companies listed on the Warsaw Stock Exchange (WSE) before and during the COVID-19 pandemic with a focus on corporate social responsibility (CSR). In order to examine this, a multivariate regression analysis was conducted. The findings show that there were no changes in the BPIs before and during the COVID-19 pandemic in companies in relation to CSR strategy. The only exception was found in the group of CSR companies that reported a lower profit margin during the COVID-19 pandemic. Companies with better BPIs may be willing to introduce CSR principles into their strategy and during the pandemic, intangibles influenced CSR strategy in a negative way. The limitations of the article are related to the study of only one market. Identified relationships allowed for a better understanding of the application of social responsibility principles among enterprises in Central Europe.

This paper proposes a decentralized planning constructed as a cyber-physical system to jointly manage supply and demand, including aspects related to production and circulation, without the mediation of money. Our aim is to provide a concrete technical solution for a future society based on communizing and commons-based resource allocation as an attempt to move in-against-and-beyond the value-form, which is the social “force-field” that characterizes the capitalist mode of production. This contribution is divided into three articulated parts: (i) a review of the elementary forms that jointly determine the capitalist social organization, (ii) a defense of the proposition that the money-form must be destroyed to enable a new mode of production based on communizing, and (iii) a proposal of a cyber-physical implementation of a jointly decentralized production planning and resource allocation over large infrastructures that enable a multilevel polycentric governance as a variation of the Interactive Economic Planning and Optimized Selections (I-EPOS) algorithm when coordination is needed.

SUMMARY Communities of microorganisms (microbiota) are present in all habitats on Earth and are relevant for agriculture, health, and climate. Deciphering the mechanisms that determine microbiota dynamics and functioning within the context of their respective environments or hosts (the microbiomes) is crucially important. However, the sheer taxonomic, metabolic, functional, and spatial complexity of most microbiomes poses substantial challenges to advancing our knowledge of these mechanisms. While nucleic acid sequencing technologies can chart microbiota composition with high precision, we mostly lack information about the functional roles and interactions of each strain present in a given microbiome. This limits our ability to predict microbiome function in natural habitats and, in the case of dysfunction or dysbiosis, to redirect microbiomes onto stable paths. Here, we will discuss a systematic approach (dubbed the N+1/N−1 concept) to enable step-by-step dissection of microbiome assembly and functioning, as well as intervention procedures to introduce or eliminate one particular microbial strain at a time. The N+1/N−1 concept is informed by natural invasion events and selects culturable, genetically accessible microbes with well-annotated genomes to chart their proliferation or decline within defined synthetic and/or complex natural microbiota. This approach enables harnessing classical microbiological and diversity approaches, as well as omics tools and mathematical modeling to decipher the mechanisms underlying N+1/N−1 microbiota outcomes. Application of this concept further provides stepping stones and benchmarks for microbiome structure and function analyses and more complex microbiome intervention strategies.

Transport properties of doped conjugated polymers (CPs) have been widely analyzed with the Gaussian disorder model (GDM) in conjunction with hopping transport between localized states. These models reveal that even in highly doped CPs, a majority of carriers are still localized because dielectric permittivity of CPs is well below that of inorganic materials, making Coulomb interactions between carriers and dopant counterions much more pronounced. However, previous studies within the GDM did not consider the role of screening the dielectric interactions by carriers. Here we implement carrier screening in the Debye-Hückel formalism in our calculations of dopant-induced energetic disorder, which modifies the Gaussian density of states (DOS). Then we solve the Pauli master equation using Miller-Abrahams hopping rates with states from the resulting screened DOS to obtain conductivity and Seebeck coefficient across a broad range of carrier concentrations and compare them to measurements. Our results show that screening has significant impact on the shape of the DOS and consequently on carrier transport, particularly at high doping. We prove that the slope of Seebeck coefficient versus electric conductivity, which was previously thought to be universal, is impacted by screening and decreases for systems with small dopant-carrier separation, explaining our measurements. We also show that thermoelectric power factor is underestimated by a factor of ∼10 at higher doping concentrations if screening is neglected. We conclude that carrier screening plays a crucial role in curtailing dopant-induced energetic disorder, particularly at high carrier concentrations.

<p><strong>Introduction. </strong>The improvement of new genetic testing strategies are getting to be progressively integrated into different parts of medicine. Progress has not been accompanied by the satisfactory level of genetic education but it has been accompanied with many ethical issues concering testing among medical students, doctors and the common population. Subsequently, the requirements for an adequate education in genetics for each group are expanding. The main goal of this paper is to examine attitudes regarding different aspects of genetic testing, and to determine differences in attitudes with respect to socio-demographic characteristics among the employees at the Faculty of Medicine in Foča, University of East Sarajevo.</p> <p><strong>Methods.</strong> Sixty-one employees of four study programs of the Faculty of Medicine in Foča participated in the research. An anonymous survey was conducted based on the voluntary consent of the respondents. It included two parts. The first part of the survey included socio-demographic questions (age, gender, educational level). The second part consisted of eight questions about genetic testing, which were related to the ethical justification of genetic testing.</p> <p><strong>Results.</strong> Out of the total number of respondents, 90.2% of respondents would undergo genetic testing for health reasons. A significantly higher number of respondents who had a master&rsquo;s degree (96.2%) would undergo genetic testing, compared to (88.9%) respondents who had an undergraduate degree (p=0.001). A significantly larger number of older respondents (29.6% over the age of 36) considered abortion justified in case of prenatal diagnosis of cancer at a later age, compared to 8.8% of the respondents belonging to the younger age group (from 26 to 35) (p=0.036).</p> <p><strong>Conclusion.</strong> We have shown that there is a different understanding among the population of different educational status and different age. Further on in the near future, it is our opinion that seminars should be organized regarding this science, in order to promote its importance.</p>

<p><strong>Introduction.</strong> With the development of medical and health sciences, research problems have become more complex, and relying solely on quantitative or qualitative research approaches is no longer sufficient. The aim of this paper was to map the progress and trends in the scientific literature regarding the application of mixed studies in medical and health sciences.</p> <p><strong>Methods.</strong> Bibliometric analysis was applied to meet the established goals. The Dimensions database was selected for literature search. The analysis unit consisted of 485 publications of various types, and the VosViewer program was employed for the analysis.</p> <p><strong>Results. </strong>The results have shown that this topic in science has experienced an exponential decline in the last year. Additionally, the most productive authors, journals, and countries have been identified, along with their collaborative networks through visual co-citation analysis. Based on the analysis of word co-occurrence, we can conclude that words like &ldquo;combined studies,&rdquo; &ldquo;problem,&rdquo; &ldquo;factors,&rdquo; &ldquo;community&rdquo; are most frequently repeated, indicating that the topics addressed in this domain mainly focus on investigating and addressing numerous issues in the field of medical and health sciences.</p> <p><strong>Conclusion. </strong>Although the results indicate a decreased interest in this topic in the last year, it does not diminish the significance of this research. Progress in medical and health sciences requires a comprehensive approach to research, which includes both quantitative and qualitative methods, such as mixed studies. Understanding the current trends and available resources for researchers assists in achieving better outcomes and improving the quality of healthcare practice.</p>

<p><strong>Introduction. </strong>Frailty is common in elderly persons and carries a high risk of poor health outcomes, including increased mortality, institutionalization, falls, and hospitalization. The aim of the work was to determine the risk factors for frailty in elderly persons.</p> <p><strong>Methods. </strong>The research was conducted in Bijeljina and Foča, in the period from February to June 2022, and was approved by the Ethics Committee of the Faculty of Medicine in Foča. A total of 243 respondents over the age of 65 took part in the research. When it comes to the instruments, the sociodemographic questionnaire, the EQ-5D-5L health questionnaire, the general sarcopenia rapid screening questionnaire SARC-F and the Kessler scale for the assessment of psychological distress were used.</p> <p><strong>Results.</strong> There were 43.6% of males and 56.4% of females participating in the research. One quarter (25%) of respondents evaluated their health as weak. Sarcopenia was identified in 28% of respondents, while 18.1% had a moderate and 11.9% a serious disorder in the field of psychological distress.</p> <p><strong>Conclusion. </strong>The presence of psychological distress and sarcopenia in a high percentage, as well as weak health status in the people over 65, is evident, which represents potential risk factors for frailty.</p>

In FMCW automotive radar applications, it is often a challenge to design a chirp sequence that satisfies the requirements set by practical driving scenarios and simultaneously enables high range resolution, large maximum range, and unambiguous velocity estimation. To support long-range scenarios the chirps should have a sufficiently long duration compared to their bandwidth. At the same time, the long chirps result in ambiguous velocity estimation for targets with high velocity. The problem of velocity ambiguity is often solved by using multiple chirp sequences with co-prime delay shifts between them. However, coherent processing of multiple chirp sequences is not possible using classical spectral estimation techniques based on Fast Fourier Transform (FFT). This results in statistically not efficient velocity estimation and loss of processing gain. In this work, we propose an algorithm that can jointly process multiple chirp sequences and resolve possible ambiguities present in the velocities estimates. The resulting algorithm is statistically efficient, and gridless. Furthermore, it increases the resolution of velocity estimation beyond the natural resolution due to its super-resolution properties. These results are confirmed by both numerical simulations and experiments with automotive radar IC.

Bridge crane is exposed to dynamic loads during its non-stationary operations (acceleration and braking). Analyzing these operations, one can determine unknown impacts on the dynamic behavior of bridge crane. These impacts are taken into consideration using selected coefficients inside the dynamic model. Dynamic modelling of a bridge crane in vertical plane is performed in the operation of the hoist mechanism. The dynamic model is obtained using data from a real bridge crane system. Two cases have been analyzed: acceleration of a load freely suspended on the rope when it is lifted and acceleration of a load during the lowering process. Physical quantities that are most important for this research are the values of stress and deformation of main girders. Size of deformation at the middle point of the main crane girder is monitored and analyzed for the above-mentioned two cases. Using the values of maximum deformation, one also obtains maximum stress values in the supporting construction of the crane.

. The progress of additive manufacturing technology brings about many new questions and challenges. Additive manufacturing technology allows for designing machine elements with smaller mass, but at the same time with the same stiffness and stress loading capacity. By using additive manufacturing it is possible to produce gears in the form of shell shape with infill inside. This study is carried out as an attempt to answer the question which type of infill, and with how much density, is optimal for a spur gear tooth to ensure the best stiffness and stress loading capacity. An analysis is performed using numerical finite element method. Two new infill structures are proposed: triangular infill with five different densities and topology infill designed according to the already known results for 2D cantilever topology optimization, known as Michell structures. The von Mises stress, displacements and bending stiffness are analyzed for full body gear tooth and for shell body gear tooth with above mentioned types of infill structure.