Multiple sclerosis is a chronic demyelinating disease of the central nervous system, that causes permanent disabilities. Diagnostics of this disease by magnetic resonance requires the appliance of corresponding protocols with the sequences that emphasize demyelinating plaques. Standard sequences T1 and T2 sometimes cannot clearly show demyelinating plaques, and it is necessary to work on perfecting the sequences that emphasize the changes in the brain formed as demyelinating plaques. The aim of the survey: The aim of the survey was to estimate the value of MR sequence with double inversion recovery (DIR) in discovering demyelinating lesions of the brain in multiple sclerosis (MS). Patients and methods of the survey: 22 patients were included in the survey, they were of both genders and different age. The patients were with diagnosed with multiple sclerosis. The patients underwent the scanning on MR apparatus 1.5 T. Comparison of DIR sequence to FLAIR and T2 W sequences were done. Result: DIR sequence proved significantly more MS lesions compared to T2W or FLAIR sequence, including intracortical, juxtacortical and paraventricular zone of the brain. In the infratentorial zone of brain, T2W sequence proved significantly more plaques compared to DIR and FLAIR. Conclusion: DIR sequence compared to T2W and FLAIR sequences discovered more demyelinating lesions in targeted regions that were examined. DIR sequence is a tool that contributes to easier and faster diagnostics of multiple sclerosis, needs to be included into the routine MR protocol of patients with MS, in order to discover more easily intracortical and juxtacortical MS lesions of the brain.

Introduction: This study aims to explore clinical values and possibilities of heart artifact elimination for patients who underwent SPECT myocardial perfusion scintigraphy. The main focus is on nuclear medicine technologists and their knowlodge of the new technologies developed in nuclear cardiology. Methods: A qualitative descriptive study, review article has been performed for this research. Pubmed, Web of Science, and Embase were searched using a predefined electronic search strategy. Eighteen studies were deemed eligible for this systematic review. Results: Based on the literature we found average age for the patients with coronary artery disease is 59.69 years for women and 57.39 yeras for men. False positive findings, blurred images, respiratory artifacts and sinogram and linogram interruption is very often, especially with patients with irregular breathing cycles, fear of the reasults, anxiety and patients with high BMI. Many studies performed on phantoms or on patients suggest image artifacts can be reduced or even eliminated with the new scanning methodology, software application upgrade, and with right nuclear medicine technologist education. Conclusion: Coronary artery disease can affect men and women equally so the best diagnostic modality is essential for adequate treatment. Interruption of sinogram or linogram, truncation of the heart and blurred image is the first sign artifact of the image. Essential and the first step of every cardiac proccesing software is sinogram and linogram inspection combined with motion correction evaluation of the raw images. New technologies can improve image quality which can increase sensitivity and specificy of myocardial perfusion scintigraphy in all patients.

: Technological development and ICT have been recognized as one of the main factors of changes in business and enterprise management. The impact of ICT in tourism has been recognised as one of the main drivers changes in the past several years. This chapters seeks to provide insight into influence of ICT on tourism and impact of ICT utilization on operations in hotels. The chapter is based on research which has been conducted among hotels and hotel managers in Bosnia and Herzegovina aiming to determine the level of ICT utilization and its impact on hotel operations and performance. The results indicate that ICT has contributed to changes in behaviour of guests as well as operations in hotels and their business performance.

Objective: This article aims to present the convergence analysis results for the Eastern Partnership EaP countries and the twenty-eight members of the European Union (EU). Research Design & Methods: The relationships between the selected macroeconomic variables and per capita GDP growth rate are econometrically tested to support this research. We analyse the convergence during the period of 2004-2017, but also include two sub-periods: 2004-2008 and 2009-2013. Findings: The empirical findings support the economic convergence hypothesis. The results show that the recent financial crisis negatively affected the absolute and conditional convergence process, when economic variables are included in the analysis. The negative effects of the crisis on conditional convergence with economic and socio-political variables are not identified. Implications & Recommendations: Poorer countries in the analysed group should do more to open their economies to attract investment, as gross fixed capital formation and economic openness have a positive impact on per capita growth, while general government debt, unemployment and inflation should be stabilised in the examined sample of countries. Contribution & Value Added: The contribution of this article is reflected in the fact that it examines a geographic and economic area that has been under examined. The analyses on the Eastern Partnership countries convergence process towards the European Union are almost nonexistent. Economic literature on convergence has focused on the EU Member States, while the analyses on the Eastern Partnership countries convergence process towards the EU are almost nonexistent. Article type: research article