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R. Ostojic, S. Vucicevic, Benjamin Fazlic, Kerim Obarcanin

High-voltage circuit breakers (HVCB), as well as power transformers, as a part of substations, undergo numerous tests during their lifetime. The first test is performed in the factory. The following is the acceptance test performed at a customer site after the delivery. The most numerous are maintenance tests performed during equipment services. All the mentioned tests require an appropriate connection between a test device and a test object, usually utilizing a large number of cables. This can be very time consuming and imposes an additional risk of obtaining appropriate measurement and assessment indices. This paper presents the potential of the wiring replacement by the wireless connection between the test object and test equipment, which would simplify, improve make the test preparation procedure and packing test equipment more convenient and faster.

K. Budimir, M. Mozzon, M. Toderi, P. D’Ottavio, M. F. Trombetta

Simple Summary The recognition of the role of food in the improvement and preservation of health is receiving more and more attention among consumers, especially in developed countries. Fats from red meats are considered quite unhealthy because of their high levels of cholesterol and saturated fatty acids. Healthier lipid profiles of red meats can be achieved by a proper feed composition of animals, but other factors, such as breed, sex, and live weight, are able to affect the nutritional properties of meats. This investigation aimed to evaluate the effect of breed (Bergamasca, Italian Merino, and Sopravissana) on the fatty acid composition of invisible (intramuscular) and visible (subcutaneous) fats of light lambs reared in Central Italy transhumant farms. They recently gained a Protected Geographical Indication label (European Union, Commission Implementing Regulation No. 475/2013), as ”Agnello del Centro Italia”. It is an income opportunity for local farms that passes through the nutritional valorization of lamb meat. The indices of nutritional quality of fats have showed that the meat of Italian Merino and Sopravissana lambs had better nutritional quality than the Bergamasca breed. Abstract Lamb meat is the main product of Central Italy transhumant farms, where lambs are traditionally reared with their mothers on pastures and are supplemented with concentrates and/or hay from day 20–30 until slaughter. However, few data are available on the fatty acid (FA) composition of unweaned lambs reared by extensive systems in Central Italy. The study aimed to evaluate the effect of breed (Bergamasca, Italian Merino, and Sopravissana) on the FA composition of intramuscular (longissimus lumborum, LL) and subcutaneous (SC) fats of light lambs. Statistical analysis showed that breed had effect only on some FAs in LL muscle fat (C18:0, C20:0, C14:1, C16:1, C17:1, C18:3 n-3, trans and conjugated linoleic acid isomers) and in SC adipose tissue (C21:0, C16:1, C18:1, C20:4 n-6, C20:5 n-3, C18:1 trans isomers). Gas chromatography data in combination with a chemometric approach could have some potential to discriminate among breeds. Indices of nutritional quality of the lipids suggested that the meat of Italian Merino and Sopravissana lambs might have better nutritional quality than Bergamasca; further studies, involving a greater number of animals, are needed to confirm these early results.

Helian Feng, Alexander Gusev, B. Pasaniuc, Lang Wu, J. Long, Zomoroda Abu-full, K. Aittomäki, I. Andrulis et al.

Previous transcriptome-wide association studies (TWAS) have identified breast cancer risk genes by integrating data from expression quantitative loci and genome-wide association studies (GWAS), but analyses of breast cancer subtype-specific associations have been limited. In this study, we conducted a TWAS using gene expression data from GTEx and summary statistics from the hitherto largest GWAS meta-analysis conducted for breast cancer overall, and by estrogen receptor subtypes (ER+ and ER−). We further compared associations with ER+ and ER− subtypes, using a case-only TWAS approach. We also conducted multigene conditional analyses in regions with multiple TWAS associations. Two genes, STXBP4 and HIST2H2BA, were specifically associated with ER+ but not with ER− breast cancer. We further identified 30 TWAS-significant genes associated with overall breast cancer risk, including four that were not identified in previous studies. Conditional analyses identified single independent breast-cancer gene in three of six regions harboring multiple TWAS-significant genes. Our study provides new information on breast cancer genetics and biology, particularly about genomic differences between ER+ and ER− breast cancer.

Oliver Feeney, G. Werner-Felmayer, H. Siipi, Markus Frischhut, S. Zullo, Ursela Barteczko, Lars Øystein Ursin, S. Linn et al.

The effective collection and management of personal data of rapidly migrating populations is important for ensuring adequate healthcare and monitoring of a displaced peoples' health status. With developments in ICT data sharing capabilities, electronic personal health records (ePHRs) are increasingly replacing less transportable paper records. ePHRs offer further advantages of improving accuracy and completeness of information and seem tailored for rapidly displaced and mobile populations. Various emerging initiatives in Europe are seeking to develop migrant-centric ePHR responses. This paper highlights their importance and benefits, but also identifies a number of significant ethical, legal and social issues (ELSI) and challenges to their design and implementation, regarding (1) the kind of information that should be stored, (2) who should have access to information, and (3) potential misuse of information. These challenges need to be urgently addressed to make possible the beneficial use of ePHRs for vulnerable migrants in Europe.

Postural orthostatic tachycardia syndrome (POTS) is a chronic, debilitating condition characterized by heterogeneous symptoms, such as lightheadedness, palpitations, pre-syncope, syncope, and weakness or heaviness, especially of the legs. It is frequently associated with hypermobile joints or conditions such as chronic fatigue syndrome, chronic abdominal pain, migraine headache, and diabetes mellitus. Described is a case of POTS, which though it is not rare, is rarely diagnosed. It can be diagnosed quickly with simple methods.

Drazen Brdjanin, Č. Zeljković, Nemanja Kitić, D. Banjac, Ivana Stakic, Cedomir Susnjar, Ranko Gavric, Nikola Vidovic et al.

The paper presents an online web-oriented system named SOLARS, which is aimed at calculating the feasibility of building the photovoltaic (PV) systems. SOLARS currently enables potential investors to calculate the technical and financial feasibility of building the PV systems in the Republic of Srpska (Bosnia and Herzegovina). Very intuitive GUI design enables investors to obtain feasibility calculations in three simple steps: (i) selection of a geographical location, (ii) specification of technical parameters, and (iii) specification of financial parameters. A usage scenario is illustrated by a real feasibility calculation example.

Emir Cogo, E. Žunić, Admir Besirevic, Sead Delalic, K. Hodzic

This paper presents a data visualization method in 3D space that includes actual positions, volumes and space relations of the chunks of data that are being visualized. Data that is being visualized is real-time information provided by the smart warehouse management system about packages distributed on pallet places within a warehouse. Three different visualizations are shown: qualitative, quantitative and cumulative. The method is graded for the time needed to determine the location of all pallet places that fulfill searched criteria and getting the exact value of searched information for each pallet place. Challenges in presenting this data and interacting with resulting visualizations are discussed. It is concluded that showing actual positions of chunks of data greatly increases the speed of acquiring searched values and positions at the same time for outliers but has issues with clusters and multiple types of queried data.

Helian Feng, Alexander Gusev, B. Pasaniuc, Lang Wu, J. Long, Zomoroda Abu-full, K. Aittomäki, I. Andrulis et al.

Previous transcriptome-wide association studies (TWAS) have identified breast cancer risk genes by integrating data from expression quantitative loci and genome-wide association studies (GWAS), but analyses of breast cancer subtype-specific associations have been limited. In this study, we conducted a TWAS using gene expression data from GTEx and summary statistics from the hitherto largest GWAS meta-analysis conducted for breast cancer overall, and by estrogen receptor subtypes (ER+ and ER−). We further compared associations with ER+ and ER− subtypes, using a case-only TWAS approach. We also conducted multigene conditional analyses in regions with multiple TWAS associations. Two genes, STXBP4 and HIST2H2BA, were specifically associated with ER+ but not with ER− breast cancer. We further identified 30 TWAS-significant genes associated with overall breast cancer risk, including four that were not identified in previous studies. Conditional analyses identified single independent breast-cancer gene in three of six regions harboring multiple TWAS-significant genes. Our study provides new information on breast cancer genetics and biology, particularly about genomic differences between ER+ and ER− breast cancer.

Kenan Turbic, Mariella Särestöniemi, M. Hämäläinen, T. Kumpuniemi, L. Correia

This paper analyses the impact of the human body on antenna radiation characteristics, with a focus on the polarization aspect. The effect of the body tissues on a wrist-worn ultra-wideband double loop antenna radiation characteristics is investigated at 3, 4 and 5 GHz, based on numerical full-wave simulations complemented with a voxel model of a hand. Results show a strong influence of the body on the gain and polarization characteristics; the radiation in the direction towards the body is suppressed by 20 dB or more, and the antenna polarization changes from a linear to an elliptical one. By simulating an off-body communications scenario with the user walking at a fixed distance from the off-body antenna, up to 6.5 dB lower received power is obtained by using the wearable antenna radiation pattern simulated with the hand phantom, compared to the case when the antenna in free space.

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