Introduction. Higher level of knowledge and frequent contacts with peers with disabilities can influence the emergence of more positive attitudes of students towards peers with disabilities. In regard to that, our aim was to test the importance of knowledge, contact frequency and other possible factors influencing attitudes of students toward disabled peers. Methods. The study included 140 students of 4th and 5th grade of primary schools. The research was conducted in the period from December 2020 to March 2021 in two primary schools. The Chedoke McMaster scale was used to examine students' attitudes toward peers with disabilities, while Contact with Disabled Persons Scale and the Children's Knowledge about Handicapped Persons Scale were used to assess frequency of contact and knowledge about disabilities. Results. Girls showed a significantly higher level (25.21±6.21) of frequency of contacts with students with disabilities compared to boys (19.66±7.30) (p=0.043) and higher level of knowledge (27.88±5.88) about disabilities compared to boys (25.50±4.69) (p=0.009). Respondents who attended school together with children with disabilities (31.07 ± 8.41) showed a significantly higher level of frequency of contacts with students with disabilities compared to respondents who did not attend school with peers with disabilities (13.72±6.32) (p=0.001). Conclusion. Higher level of knowledge and frequent contacts with peers with disabilities does not have influence on the emergence of more positive attitudes of students towards peers with disabilities.

Nowadays, companies face numerous challenges to operate successfully and remain competitive in the market. Globalization is increasing competition in the market, allowing many companies to operate in foreign markets. Increasing competition has made companies constantly trying to increase their productivity while reducing costs. To meet all the requirements, and at the same time function in the best possible way, companies must be organized adequately, taking into account the whole set of processes from the company's internal organization to the company's appearance on the market. It means, if the end-user is to be satisfied, the company must implement quality in all phases of business, ie business ethics and company culture, through the quality of technology, personnel, etc. In other words, it must be satisfied the system quality of the company, known in the literature as QMS (Quality Management System). The main purpose of this paper is to review the multiple understanding of the concept of QMS and its different underpinning theories in a business to customer context. The design of this research is based on mere documentary analysis and some observations.

From the very knowledge of Industry 4.0, its implementation is carried out in all segments of society, but we still do not fully understand the breadth and speed of its implementation. We are currently witnessing major changes in all industries, so new business methods are emerging. There is a transformation of production systems, a new form of consumption, delivery, and transportation, all thanks to the implementation of new technological discoveries that cover robotics and automation, the internet of things (IoT), 3D printers, smart sensors, radio frequency identification (RFID), etc. Robotic technology is one of the most important technologies in Industry 4.0, so that the robot application in the automation of production processes with the support of information technology brings us to smart automation (i.e., smart factories). The changes are so deep that, from the perspective of human history, there has never been a time of greater promise or potential danger.

International Physics Conference in Bosnia and Herzegovina (PHYCONBA 2020) Organizer: Physical Society in Federation of Bosnia and Herzegovina with support of the Academy of Sciences and Arts of Bosnia and Herzegovina Date: October 19, 2020 Venue: Premises of The Academy of Sciences and Arts of Bosnia and Herzegovina, 7 Bistrik street, Sarajevo, Bosnia and Herzegovina. Memebers of Organizing committee: 1. Maja Đekić (Faculty of Science, University of Sarajevo), chairwoman, 2. Mirza Hadžimehmedović (Faculty of Science, University of Tuzla), member, 3. Rifat Omerović (Faculty of Science, University of Tuzla), member, 4. Ena Žunić-Ćejvanović, member, 5. Amra Salčinović Fetić, (Faculty of Science, University of Sarajevo), Technical secretary, 6. Benjamin Fetić (Faculty of Science, University of Sarajevo), member Members of Scientific committee: 1. Dejan Milošević (Faculty of Science, University of Sarajevo, Academy of Sciences and Arts of BiH), chairman, 2. Dijana Dujak (Faculty of Electrical Engineering, University of Sarajevo), member, 3. Hedim Osmanović (Faculty of Science, University of Tuzla), member, 4. Siniša Ignjatović (Faculty of Natural Sciences and Mathematics, University of Banja Luka), member.

In this paper we will present the Julia set and the global behavior of a polynomial second-order difference equation of type xn+1 = axmn xx-1 + axm+1 n-1 + bxn-1 where m ? N, a > 0 and b ? 0 with non-negative initial conditions.

This research presents the first findings on thrombopoiesis for Wistar rats. Haemopoietic cells from the femur and the sternum were analysed by light microscopy in combination with infrared and near-ultraviolet light for fine cytoplasmic structure analysis. Five main types of thrombocyte precursor cells were identified in the bone marrow samples: megakaryoblast, promegakaryocyte and megakaryocyte (basophilic, acidophilic and thrombocytogenic). More intensive thrombopoiesis and morphologically differentiated cells were found in sternum samples.

U ovom radu ponudit će se rodna analiza potreba i mogućih pravaca reforme izbornog zakonodavstva Bosne i Hercegovine. Fokus rada će biti na tri centralna istraživačka pitanja. Prvo, analizirat će se u kojoj mjeri i na koji način konsocijacijski politički sistemi o(ne)mogućavaju predstavljanje žena u politici. Pri tome će se u obzir uzeti različite dimenzije predstavljanja (formalno, deskriptivno, sadržajno i simbolično predstavljanje). Drugo, analizirat će se da li je Izborni zakon Bosne i Hercegovine usklađen sa Zakonom o ravnopravnosti spolova Bosne i Hercegovine. I treće, ispitivat će se u kojem pravcu se trebaju i mogu odvijati reforme izbornog zakonodavstva BiH. U tom kontekstu biće predstavljene i preporuke CEDAW komiteta i različite rodno odgovorne inicijative za reforme izbornog zakonodavstva koje dolaze kako od institucija nadležnih za rodnu ravnopravnost, tako i iz sfere civilnog društva.

Background/Aim: Organophosphorus compounds (OP) bind to acetylcholinesterase (AChE) causing an irreversible inhibition of the enzyme. When doing in vivo studies of OP intoxication, to precisely measure AChE activity in the brain tissue it is necessary to remove as much blood from the brain as possible. By doing so, interference of the OPs present in the blood is avoided. Usually this demands expensive equipment, therefore, the aim of this study was to find a simple and economical method to eliminate the blood from brain blood vessels. Methods: Wistar albino rats were divided into four groups named Control (C), Control washout (CW), Paraoxon (Pox) and Paraoxon washout (PoxW) group. Rats in Pox and PoxW were treated with 0.25 mg/kg paraoxon subcutaneously (sc), while C and CW received 1 mL/kg sc saline instead. The "Marinković-Maksimović" ("MM") method was performed in rats from PoxW and CW groups. Activity of AChE was measured both in erythrocyte lysate and in brain tissue using spectrophotometry. Results: Macroscopic examination revealed that the elimination of blood was achieved in CW and PoxW groups. Activity of AChE in homogenised brain tissue was expectedly lower in the Pox and PoxW group, when compared to C and CW group, respectively. The CW group had a lower value of AChE activity in the brain tissue compared to C group, while activity of AChE in the PoxW group was statistically higher than in the Pox group (p = 0.044). Conclusion: The MM method provides good elimination of blood from the brain. Together with blood, present confounding factors that interfere with analysis in homogenised brain tissue, were also eliminated.

Background/Aim: In surgery, and especially in the neurosurgical operations, maintenance of cardiovascular stability during and in the phase of the immediate postoperative recovery is of vital importance. The aim of this study was to investigate the effects of continuous esmolol infusion on the values of cardiovascular parameters and quality of the emergence from anaesthesia in neurosurgical patients. Methods: A total of 40 patients of both sexes scheduled for elective supratentorial surgery were randomly assigned to two groups. Esmolol group received intravenous (iv) infusion of esmolol dissolved in 5 % glucose solution (during the first 5 min at a rate of 0.3 mg/kg/min and thereafter at a rate of 0.1 mg/kg/min), while the ones from the control group received a 5 % glucose solution without esmolol at the same volume and rate. Cardiovascular parameters were registered at critical phases of anaesthesia and operation (induction, intubation, placement of Mayfield frame, craniotomy, skull closure, extubation). Recovery after anaesthesia was assessed based on times of eye opening on command, spontaneous eye opening and regaining of full orientation. Results: Values of systolic blood pressure and heart rate were significantly lower in the esmolol than in the control group of patients. Although the durations of anaesthesia did not differ, patients from the esmolol group required significantly less opioids and isoflurane and recovered after the anaesthesia significantly faster than the patients in the control group. Conclusion: Ultrashort-acting beta-adrenergic receptor antagonist esmolol, administered as a continuous iv infusion, assures better cardiovascular stability and smoother emergence from the balanced inhalation general anaesthesia than the control glucose infusion in elective neurosurgical patients.

Introduction: Oganophosphorus compounds (OP) bind to acetylcholinesterase (AChE) and inactivate it. In the synaptic cleft, undestroyed and accumulated acetylcholine produce the acute cholinergic effects. The aim of this study was to determine the frequency, speed of onset and intensity of certain signs of paraoxon poisoning depending on dose and outcome of poisoning. Methods: The study was conducted in adult Wistar rats. The median lethal dose (LD50) of paraoxon as well as protective ratio (PR) of atropine (10 mg/kg intramuscularly) was determined. Clinical signs of poisoning were observed: fasciculations, tremor, seizures, ataxia, piloerection, lacrimation, exophthalmos, bizzare/stereotypic behaviour and dyspnoea. The time from paraoxon injection to the first appearance of the sign of poisoning was recorded as well as the intensity of poisoning with evaluation at 10 time intervals throughout the 4 h observational period. Results: The LD50 of paraoxon was 0.33 mg/kg (subcutaneously) and PR of atropine was 2.73. Dose-dependent, piloerection occurred more often (p = 0.009) and at higher intensity (p = 0.016) at higher doses. Fasciculations, tremor, seizures and ataxia occurred significantly earlier at higher doses of paraoxon (p = 0.015, 0.002, 0.021 and 0.016, respectively), as well as the intensity of seizure, tremor and fasciculation. Piloerection (p = 0.002) and seizures occurred more frequently (p = 0.009) in non-survivors. Fasciculations, tremor, seizures and ataxia occurred significantly earlier and at higher intensity in non-survivors (p < 0.001, for all parameters), as well as dyspnoea (p = 0.009 and p = 0.048). In atropine-protected rats, nicotinic effects persevered, so they were the prognostic parameter of the severity of the poisoning. Conclusion: Seizures and fasciculations followed by tremor were strong prognostic parameters of the probability of lethal outcome of paraoxon poisoning. Also, the mentioned poisoning signs were with their intensity and speed of occurrence in a clear positive correlation with the administered dose of paraoxon. Even at high doses of paraoxon, atropine blocked the muscarinic (but not nicotinic) effects and somewhat mitigated the CNS toxic effects.