Recent technological advances in the field of genomics offer conservation managers and practitioners new tools to explore for conservation applications. Many of these tools are well developed and used by other life science fields, while others are still in development. Considering these technological possibilities, choosing the right tool(s) from the toolbox is crucial and can pose a challenging task. With this in mind, we strive to inspire, inform and illuminate managers and practitioners on how conservation efforts can benefit from the current genomic and biotechnological revolution. With inspirational case studies we show how new technologies can help resolve some of the main conservation challenges, while also informing how implementable the different technologies are. We here focus specifically on small population management, highlight the potential for genetic rescue, and discuss the opportunities in the field of gene editing to help with adaptation to changing environments. In addition, we delineate potential applications of gene drives for controlling invasive species. We illuminate that the genomic toolbox offers added benefit to conservation efforts, but also comes with limitations for the use of these novel emerging techniques.

Accurate information on the cause of death is obtained from expert teams based on pathological or forensic expertise. Reliable information can be obtained from physicians in hospital settings if the deceased person has been treated in such an institution and has previously been diagnosed with an illness (intrahospital mortality). Intrahospital mortality analysis provides reliable data that can be used in the planning of a bed fund, the amount of medication purchased, the purchase of equipment, the organization and creation of highly specialized medical teams (resuscitation team), the number of resuscitation procedures, the number of pathologists required for autopsy procedures, etc. The aim of the study was to determine the total number of deaths, to identify the most common causes of death and 10 leading diagnoses of deceased patients at the Internal Medicine Clinic, University Clinical Center Tuzla (UKC) during one calendar year (2011). Material and methodes: Archive material (case histories and reports of deceased patients of the Internal Medicine Clinic) were used. Results: During this period, 6 488 patients were treated at the Internal Medicine Clinic and 451 patients died. According to the analyzed data, the most common diagnoses and causes of death at the Internal Medicine Clinic were: cerebrovascular incidents 104 (20.84%), cardiogenic shock in 24 (5.31%), heart failure 59 (10.86%), hepatic coma with cirrhosis of the liver 25 (5.33%), sudden cardiac death 30 (6.53%), respiratory failure 15 (3.32%), myocardial infarction 41 (9.99%), multiorgan failure 18 (4.00%) , pulmonary edema 14 (3.10%), sepsis 6 (1.38%), pulmonary emboli 17 (3.82%), valvular heart disease 9 (1.92%), cardiorespiratory arrest 9 (1.92%) , malignant abdominal neoplasms in 23 (5.28%), pancreatitis 2 (0.44%), hematemesis 8 (1.76%), diabetes mellitus 4 (0.88%), lung tumor 1 (0.22%), chronic renal insufficiency 12(2.54%), suicidal intoxication 4 (0.88%), ileus 4 (0.88%), cachexia 3 (0.66%), restrictive cardiomyopathy 2 (0.44%), mesenteric thrombosis arteries 2 (0.44%), disseminated lupus erythematosus 2 (0.44%), coffee vein thrombosis inferior 2 (0.44%), and 1 (0.22%) died of an aneurysm aortic abdominalis, ventricular septal defect, amyloidosis, disseminated intravascular coagulation, systemic sclerosis, rheumatoid arthritis and breast tumors. Conclusion: During the analyzed period, 6488 patients were treated at the Internal Medicine Clinic and a total of 451 patients died. The most common cause of death in hospitalized patients is cardiovascular disease (n = 208; 41.68% of deaths), with cerebrovascular disease (n = 104; 20.84% of deaths) totaling 312 (62.25%) of deaths from cardio and cerebrovascular disease.

An analysis workflow has been developed to assess energy deposition and material damage for ITER vertical displacement events (VDEs) and major disruptions (MD). This paper describes the use of this workflow to assess the melt damage to be expected during unmitigated current quench (CQ) phases of VDEs and MDs at different points in the ITER research plan. The plasma scenarios are modeled using the DINA code with variations in plasma current I p, disruption direction (upwards or downwards), Be impurity density n Be, and diffusion coefficient χ. Magnetic field line tracing using SMITER calculates time-dependent, 3D maps of surface power density q ⊥ on the Be-armored first wall panels (FWPs) throughout the CQ. MEMOS-U determines the temperature response, macroscopic melt motion, and final surface topology of each FWP. Effects of Be vapor shielding are included. Scenarios at the baseline combination of I p and toroidal field (15 MA/5.3 T) show the most extreme melt damage, with the assumed n Be having a strong impact on the disruption duration, peak q ⊥ and total energy deposition to the first wall. The worst-cases are upward 15 MA VDEs and MDs at lower values of n Be, with q ⊥,max = 307 MW m−2 and maximum erosion losses of ∼2 mm after timespans of ∼400–500 ms. All scenarios at 5 MA avoided melt damage, and only one 7.5 MA scenario yields a notable erosion depth of 0.25 mm. These results imply that disruptions during 5 MA, and some 7.5 MA, operating scenarios will be acceptable during the pre-fusion power operation phases of ITER. Preliminary analysis shows that localized melt damage for the worst-case disruption should have a limited impact on subsequent stationary power handling capability.

Generative (grammar) means precisely formulated, explicit grammar. American linguist A. N. Chomsky strove for such a maximally precise, universal grammar. He bases the foundation for his thoughts on the possibility of the existence of a universal grammar on his own belief that the ability for language is inherent in human beings, i.e., that the grammatical structure not only of our own language, but of language in general, is engrained in our minds. This syntactician is interested not only in the definition and analysis of the sentence structure, but also in the inherent relation between grammar and logic. Chomsky’s starting point is that it is possible, within the confines of one language, to form an infinite number of statements using a finite number of words (Glovacki-Bernardi, et al., 2007, p. 190.); while doing so, the focus is on grammatically correct, meaningful statements, as in the opposite situation, grammatical rules which point to the logical relationship within them would lose their meaning. This is, at the same time, one of the foundations of his generative theory. Chomsky confirmed a set of rules through which he attempted to place grammar into a universal framework within which every language can find the laws ruling its own logical grammatical functioning. In applying these laws, it is possible to form paradigms which will serve as indicators of structural differences and similarities between languages, which we will demonstrate in this paper using examples from French and Latin.

E. T. A. Hoffmann was a multi-talented artist who was not only known as a writer but as well as a composer and a draftsman. These talents can be noticed through various traces within his literary work. The references to the fine arts characterize Hoffmann’s entire oeuvre from the early to the late phase. The interest in certain artists and works, which Hoffmann adopted both in Dresden and during the Bamberg and Berlin periods, can be encountered through various references, especially within his narratives. The presented article includes three story collections: Fantasiestücke in Callots Manier,. Blätter aus dem Tagebuche eines reisenden Enthusiasten (1814/15), Nachtstücke (1816/17), and Die Serapionsbrüder (1819/21). It begins by referring to Hoffmann’s engagement with various artistic models, and then goes on to examine the traces of these encounters. The approach divides the references into four categories that within selected narratives reference to different features. Hoffmann not only relays on the traditionally painterly genres of fantasy and nocturne, but also attempts to transpose their characteristics into literature. The works of visual artists can serve as narrative prompts, or to shape the protagonist and landscape depictions. The above-mentioned references contribute to a better understanding of Hoffmann’s narrative work, both on the poetological level and on the level of content.

Teaching methodology is a key segment in the initial education of future teachers. It is a science that studies legality in the field of teaching and learning, but in a specific, clearly defined field of activity. That is, it is a science that explores what to learn, how to learn and teach, as well as how and with what support certain teaching contents are learned. Future teachers, during their initial education, in parallel with the professional knowledge from selected subjects of study, acquire knowledge, develop skills and attitudes on how to teach this subject of study and how future generations will acquire, adopt, form knowledge and skills through their own activity. The aim of this paper is to determine the representation of teaching methodology with school practice in study programs for the education pre-service science teachers. Based on the aim, a qualitative research was conducted, in which the legal provisions regulating the teaching processes at the University of Sarajevo were primarily analysed, with an emphasis on the pedagogical-psychological and didactic methodological group of subjects in the study programs for education of pre-service science teachers at the University of Sarajevo. The total of 11 teacher education programs for education of pre-service science teachers at the Faculty of Science, University of Sarajevo, were analyzed. The analysis and description of official study programs that prepare future science teachers showed an unequal treatment of teaching methodology practices in the study programs of this higher education institution. We identified different approaches in creating goals and outcomes for teaching content from teaching methodology, unequal number of ECTS credits for this segment of initial education, and also the specifics of certain teaching methodology in study programs have been recognized. The results and recommendations can offer ideas for reflection that will improve the initial education for education of pre-service science teachers. The results of the research also emphasize the responsibility of university teachers in the process of creating curricula with an emphasis on pedagogical-psychological and didactic-methodological area.

A 37-year-old man presented with jaundice, upper right quadrant pain, and intermittent fever with chills. Laboratory assessment showed biliary stasis, with total bilirubin of 203 µmol/L (2–20), conjugated bilirubin of 105 µmol/L, and alkaline phosphatase of 556 U/L (30–120). Markers for hepatitis A–E viruses were negative. Serology assessment for rubeola, herpes simplex virus, Epstein-Barr virus, and Toxoplasma gondii showed negative IgM antibodies. HIV serology status was negative. For cytomegalovirus, both types of antibodies (IgM and IgG) were positive, with an IgM level >300 U/mL. pp65 antigen was also detected as well as CMV DNA. Diagnostic imaging of the abdomen except the dilated common bile duct showed a normal appearance of the gallbladder, liver, pancreas, spleen, and both kidneys. To our knowledge, cytomegalovirus cholangiopathy in the absence of any other underlying disease has not been reported. Therefore, the presence of cholangiopathy in our patient is interesting from an imaging, laboratory, and clinical point of view.

The paper deals with the problem of poor acquisition of English nominal compounds in EFL university students who are native speakers of Bosnian/Croatian/Serbian (BCS). The problem was tackled by a brief comparison of noun morphology and declension suffixes in English and BCS, the introduction of negative transfer in the process of foreign language acquisition, and the analysis of BCS translation equivalents. The discussion revealed that the productivity of compounding largely depends on the complexity of noun morphology. Put simply, the more complex noun morphology is, the less productive compounding will be. In addition, the analysis of the translation equivalents also highlighted that a vast majority of problems related to poor acquisition of English nominal compounds stems from the fact that EFL learners usually translate L1 phrases word-forword into L2. Finally, it was pointed out that teaching English nominal compounds to EFL learners could be improved by tailored-made instructions provided in L1.

∗ Socially-Assistive Robots (SARs) hold great potential to revolutionize the way we manage chronic illness outside clinical settings, but a current limitation to their broad adoption for this purpose is the lack of “ground truth” around interactions between robots and humans in in-home settings. Such ground truth is a necessity for using robotic sensor data for machine learning models of patient activity patterns or to create AI to customize robotic interactive behavior autonomously. Traditional subjective recall-based data collection methods lack the fine-grained temporal detail to support such AI development, as well as suffering from “recall bias” effects. One potential solution to this challenge is to adapt novel forms of interaction assessment, such as ecological momentary assessment (EMA), to collect patient interaction data in real-time . Here we describe a pilot study utilizing such an EMA system with SARs. We describe the development of the EMA framework, theoretical design issues, and lessons learned. Preliminary machine learning results indicate 75-80% accuracy for detecting specific interaction modalities. We also discuss the potential utility of EMA for exploring cross-cultural differences with in-the-wild robot use, and as a tool to support participatory design research on robotics in healthcare settings.

The study investigates the influence of alluvial-lacustrine processes and paleoclimate variations on the distribution of terpenoids and unsubstituted Polycyclic Aromatic Hydrocarbons (PAHs). The XRF, ICP-MS, Rock-Eval, and organic geochemical analyses were employed to investigate thirty Lower and Middle Miocene sedimentary samples from the Prebreza and Čučale formations, collected from boreholes BL3 and BL5, situated in the central part of the Toplica Basin (Serbia). The development of the studied basin part was influenced by alluvial-lacustrine processes, which affected the type of organic matter (OM) and the paleoenvironment. Sandy silt and gravel layers in the profile of the BL3 borehole indicate the contribution of thicker clasts brought by rivers. In the BL5 borehole, there are fine-grained intrabasinal lacustrine sediments in the lower part, and swamp sediments in the upper part. The lowest total organic carbon (TOC) content is in alluvial sediments of BL3 and some lacustrine sediments of BL5. Based on Hydrogen Index (HI) and C/N ratio, various mixtures of terrigenous and algal organic matter are present in the sediments, while an increase in the proportion of terrestrial organic matter with higher HI (Type II kerogen) is recorded in upper parts of both boreholes, which may be related to paleoclimatic changes. Based on Tmax, the OM is immature and/or in the initial stage of maturity. The presence of plant terpenoids and unsubstituted PAHs, which reflected paleoflora and paleoclimate changes, was associated with the suggestion of predominating Type III kerogen in the studied sediments. Various factors influenced the application of gymnosperms/angiosperms parameters. For instance, the progressive aromatization of triterpenoids occurred in the BL5, whereas the process was hindered in the upper part of the BL3, probably as a result of high sedimentation rates. Based on C-value, Sr/Cu, and Rb/Sr ratios, during the deposition of the Lower and Middle Miocene formations of Čučale and Prebreza, a warm and humid climate prevailed, reflecting the Middle Miocene Climatic Optimum (MMCO). The production of unsubstituted PAHs in the studied samples probably relates to paleo-wildfires, anoxic conditions, or the presence of specific biomass precursors.