The problems of traffic safety and the profession of traffic safety are universal problems that require constant strengthening of the system of education and innovation both in syllabuses and in technologies and techniques applied in the field of traffic safety. The purpose of the innovative approach to the education program is to educate undergraduate and graduate students in the field of traffic safety, in accordance with the needs of society, which should provide an interdisciplinary and multidisciplinary approach to safety of all road users, technical solutions and social response to traffic accidents. Traffic safety problems are complex problems, which is why the competencies and skills acquired by engineers should provide knowledge and a deeper understanding of risk while strengthening the applied and practical skills. Innovative study programs must have a common basis for all directions, with a deep knowledge of mathematics, physics and mechanics with an emphasis on a holistic and interdisciplinary approach to the use of engineering in improving traffic safety.

The paper lists the major projects of international financial organizations in Bosnia and Herzegovina (BiH) after signing the Dayton Peace Agreement to explore the role of international financial organizations in post-Dayton BiH. It discusses the specific contribution and the role of these organizations in functioning of BiH, including financial assistance, credit means, various funds and projects, which have been supposed to lead to the stable functioning of BiH after the signing of the Dayton Peace Agreement. The paper explains the role and attentiveness of the Monetary Board in BiH with a focus on its impact on implementation of the international projects. The research question is: “From which sources did the largest funds in BiH come in the period from 1996 to 2020 and how were they related to GDP?”. The paper is based on publicly available data from international financial institutions and the Ministry of Civil Affairs of BiH. The results show that about 71.45 billion dollars entered BiH from international financial institutions through donations, grants, loans, and other various types of assistance. But the funded projects did not have the same priorities every year and in every area. In addition, international funds were used to finance numerous projects aimed at economic recovery and economic development. In the last few years, there

With the advent of novel 2D materials and their rich optical and electronic properties, nonlinear interactions in these systems are receiving great attention due to the scalability potential and production of nanoscale nonlinear devices for applications in frequency conversion devices, advanced laser systems and quantum technologies research and applications.

Evidence-based Clinical Guidelines (CGs) for Good Clinical Practice (GCP) have emerged to synthesize and systematize a wealth of knowledge from scientific journals that health professionals have been unable to follow. Today, the COVID 19 pandemic requires them more than ever. CGs are defined as a set of systematized claims, based on a systematic analysis of scientific evidence, that point to the performance of GCP; contain an assessment of the usefulness and harmfulness of various diagnostic and therapeutic options. "The Good": CG is necessary for health professionals, patients and society, because the knowledge gained in studies is insufficient to perform GCP in further practice. "The Bad": The shortcomings of the CG stem from; (a) there are still many unknowns in medicine, as funding for scientific research is inadequate; (b) the disunity of different institutions that make recommendations at the global, even local level results in different guidelines, although they are based on identical scientific papers as evidence; (c) most clinical scientific studies exclude groups of patients that make up a significant population in everyday practice and the guidelines more or less (do not) apply to them; (d) the impossibility of implementing the CG, because they are not backed by state regulatory bodies and / or the economy cannot follow them. "The Ugly": (a) the ambition of a large number of practitioners and researchers to be among the authors of the guidelines, although many do not have competence for the subject matter; (b) industry (equipment, drugs, supplements) most often funds scientific research and the interdependence of industry and the "dependence" of the authors of guidelines is often intertwined; and (c) publishing (un) intentionally falsified study results which then serve to "support" some guidelines. often in (un) intentional alliance with the editors of the world's elite medical journals.

Background: HIV-positive patients may present lung infections differently, which may hinder differential diagnoses and the choice of treatment in the course of COVID-19, especially in countries with limited access to high standard healthcare. Here we aim to investigate the association between radiological changes and poor COVID-19 outcomes among HIV-positive patients from Central and Eastern Europe. Methods: Since November 2020, the Euroguidelines in Central and Eastern Europe Network Group started collecting observational data on HIV and COVID-19 co-infections. In total, 16 countries from Central and Eastern European submitted data (eCRF) on 557 HIV-positive patients. The current analyses included patients who had a radiological examination performed. Logistic regression models were used to identify the factors associated with death, ICU admission, and partial recovery (poor COVID-19 outcomes). Factors that were significant in the univariate models (p<0.1) were included in multivariate model. Results: Radiological data were available for 224 (40.2%) patients, 108 (48.2%) had computed tomography, and 116 (51.8%) had a chest X-ray. Of these, 211 (94.2%) were diagnosed using RT-PCR tests, 212 (94.6%) were symptomatic, 123 (55.6%) were hospitalized, 37 (16.6%) required oxygen therapy, and 28 (13.1%) either died, were admitted to ICU, or only partially recovered. From the radiologist’s description, 138 (61.6%) patients had typical radiological changes, 18 (8.0%) atypical changes, and 68 (30.4%) no changes. In the univariate models, CD4 count (OR=0.86 [95% CI: 0.76–0.98]), having a comorbidity (2.33 [1.43–3.80]), HCV and/or HBV co-infection (3.17 [1.32–7.60]), being currently employed (0.31 [0.13–0.70]), being on antiretroviral therapy (0.22 [0.08–0.63]), and having typical (3.90 [1.12–13.65]) or atypical (10.8 [2.23–52.5]) radiological changes were all significantly associated with poor COVID-19 outcomes. In the multivariate model, being on antiretroviral therapy (OR=0.20 [95% CI:0.05–0.80]) decreased the odds of poor COVID-19 outcomes;while having a comorbidity (2.12 [1.20–3.72]), or either typical (4.23 [1.05–17.0]) or atypical (6.39 [1.03–39.7]) radiological changes (vs no changes) increased the odds of poor COVID-19 outcomes. Conclusions: Among HIV patients diagnosed with symptomatic SARS-CoV-2 infection, the presence of either typical or atypical radiological COVID-19 changes independently predicted poorer outcomes.

Uvod: Ranije se smatralo da prestanak moždane funkcije nastaje zbog gubitka respiratorne i cirkulacijske funkcije i uistinu gubitak moždane aktivnosti se smatrao ključnom komponentom smrti. Razvojem aparata za održavanje u životu kao što su respiratori i aparati za potporu cirkulaciji, definicija smrti i moždane smrti se počela modifikovati. Korištenjem različitih dijagnostičkih metoda i upotrebom dodatnih testova, došlo je do novih saznanja i do povećanog interesovanja u dijagnostici moždane smrti radi predviđanja ishoda bolesti ili eventualne transplantacije organa kod osoba sa utvrđenom moždanom smrti. Cilj: Utvrditi značaj kompjuterizirane tomografije (CT) kod potvrđivanja moždane smrti. Prikazati ulogu BA radioloških tehnologija u dijagnostici moždane smrti CT-om. Metode: Sistematska pretraga literature preko internet pretraživača PubMed. Uključeni su članci u kojima je pisano o moždanoj smrti, dokazivanju moždane smrti, te primjeni dijagnostičke CT-a, u periodu između januara 1996. i juna 2022. godine Rezultati: Pronađeno je 10 naučnih članaka koji su razmatrali moždanu smrt, dijagnostičke metode kod dokazivanja moždane smrti te primjenu i prednosti pojedinih metoda u dokazivanju moždane smrti. Zaključci: CT je metoda koja se koristi za potvrđivanje moždane smrti jer pokazuje izostanak opacifikacije kortikalnog segmenta srednje cerebralne arterije u obje hemisfere te odsustvo pojačanja unutrašnjiih vena koji se ujedno smatraju i najboljim CT kriterijem kod moždane smrti.

: Complexes of general formula [ Ru(bpy) 2 (L) ]CF 3 SO 3 , where bpy = 2,2′ - bipyridine, and L = Schiff bases derived from salicylaldehyde and amino acids (glycine ( 1a), cysteine (1b), methionine (1c ) and phenylalanine ( 1d )) were synthesized. Characterization based on elemental analysis, Ru content, mass, infrared and electronic spectra confirmed RuN 5 O coordination unlike 1b where coordination occurred via azomethine nitrogen and cysteine sulfur. Cyclic voltammograms, except 1b, showed several quasi- reversible redox pairs in the positive potential range, the first located at about 0.5 V, corresponding to similar heteroleptic Ru(II) bipyridyl complexes. Biological activity was tested by interactions with DNA and BSA. DNA binding constants of order 10 3 M − 1 , suggest groove binding due to bpy ligand and hydrogen bonding of the OH and CO groups from the imine moiety. In vitro BSA protein inhibition assay performed by spectrofluorimetry showed Complex : BSA binding in 1 : 1 ratio with K b of 10 4 M − 1 order. Cytotoxicity studies by MTT assay for 72 h of drug action revealed activity of 1a and 1d against breast cancer MCF- 7 cells with IC 50 values 32 ± 8 and 26 ± 1µM, respectively.

In this paper, a novel method for the magnetic flux density estimation in the vicinity of multi-circuit overhead transmission lines is proposed. The proposed method is based on a fully connected feed-forward artificial neural network model that is trained to estimate the magnetic flux density vector components for a range of single-circuit overhead transmission lines. The proposed algorithm is able to simplify estimation process in instances when there are two or more geometrically identical circuits present in the multi-circuit overhead transmission line. In such instances, artificial neural network model is employed to estimate the magnetic flux density distribution over a considered lateral profile for only one of such circuits. The magnetic flux density estimates of the other geometrically identical circuits are derived from these results. The proposed methodology defines the resultant magnetic flux density for the multi-circuit overhead transmission line in terms of the contributions made by individual circuits. The application of the proposed magnetic flux density estimation method is demonstrated on several multi-circuit configurations of overhead transmission lines. The performance of the proposed method is compared with the Biot-Savart law based method calculation results as well as with field measurement results.

Introduction. Lean principles have been successfully adapted to the healthcare environment, enabling hospitals and clinics to streamline their operations and focus on value as perceived by their patients. Many healthcare facilities have implemented lean principles to improve their efficiency. The subject of this paper is the lean concept, the essence of which is implementation of methods that affect the efficiency and quality of providing health services. Our aim was to point out the necessity of applying modern concepts in healthcare. Material and Methods. The primary sources of data were obtained through research on the opinions and possibility of applying the lean concept in hospitals in Bosnia and Herzegovina. We presented the results on the effectiveness of the lean concept in hospitals that apply it. Results. After implementation of the lean concept in an Italian hospital, the results showed a positive impact on the waiting time for admission, faster discharge, and faster flow of information. The results of the research in Bosnia and Herzegovina showed that there were positive attitudes towards the effects that would be achieved by implementing the lean concept. Conclusion. The implementation of the lean concept would reduce medical waste, which would positively affect the quality of health care services.

The aim of our manuscript is to report of a successful perinatal outcome after treatment of acute polyhydramnios caused by duodenal atresia. A 34-year-old G3P1 was referred due to polyhydramnios in the 30th week of pregnancy. Ultrasound revealed polyhydramnios, amniotic fluid index (AFI) 28, and a double bubble sign that indicated duodenal atresia and dilatated oesophagus. In the 32nd week of gestation, the volume of amniotic fluid increases, AFI 35, along with symptoms of dyspnea and abdominal pain. Due to the clinical picture and the early gestational age, it was decided to perform an amnioreduction. In the 36th week of gestation cesarean section was performed. The baby was taken for exploratory laparotomy and found to have a simultaneous complete duodenal atresia and annular pancreas with associated dilated the first portion of the duodenum and the stomach. A side-to-side duodenoduodenostomy via single-layer hand-sewn anastomosis was performed over a transanastamotic feeding tube (TAFT). The postoperative course was uneventful. Amnioreduction is useful and safe in the treatment of acute polyhydramnios caused by duodenal atresia and thus has a significant role in prolonging gestation until fetal maturity.

Reading is one of the most important academic skills that children master in the early grades of elementary school. The simple view of reading postulates that it consists of decoding abilities and linguistic understanding. The present study aims to explore the development of decoding abilities in the Bosnian language in children from Grade 3 to Grade 5. We assessed the relationships between word reading and pseudoword reading as measures of decoding skills, and phonemic deletion task, rapid automatized naming (RAN) of letters, and RAN of objects as the predictors of decoding skills. The sample for this study comprised 36 children (16 girls, 20 boys). This study’s results showed a significant improvement in decoding skills from Grade 3 to Grade 5. The best predictor of word reading in Grade 5 was RAN of objects in Grade 3, followed by RAN of letters in Grade 3. On the other hand, the significant predictors of pseudoword reading in Grade 5 were RAN of objects and the phoneme deletion task in Grade 3. Understanding reading development from Grade 3 to Grade 5 is informative and can help create better reading instruction for all readers.