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Z. Su, D. McDonnell, A. Cheshmehzangi, J. Ahmad, Hengcai Chen, S. Šegalo, Yuyang Cai

[This corrects the article DOI: 10.3389/fpubh.2022.795841.].

Alija Salkunić, J. Vuković, S. Smiljanić

Phosphorus is essential to the growth of living organisms, and, therefore, its pres ence is considered vital for all forms of life. Research shows that phosphate rock reserves are reducing. Phosphate rock is used as raw material for the production of phos -phate-based fertilizers, and its lack of supply could have adverse effects on the global food supply. New resources that can be a potential replacement for phosphate rock in the production of fertilizers and other phosphorus-containing substances are investigated. This paper provides an overview of technology implementations, methods, and process es, as well as the latest achievements in the field of phosphorus recovery from waste streams. Different methods of phosphorus regeneration from sewage sludge and solid waste, and forms of phosphate regeneration are described. In addition, an overview of the following methods is given: nanonucleation, adsorption and ion exchange, solar evapora tion, biological assimilation of P, and membrane technologies.

Aim The aim of this study was to link the values of D-dimer and C-reactive protein (CRP), with the occurrence of pericardial effusion in patients who had coronavirus disease 2019 (COVID-19) and have preserved systolic function of the left ventricle (LV). Methods This was a prospective study and included 146 patients who underwent echocardiographic examination 30 days after the acute phase of COVID-19. Patients who were placed on mechanical ventilation, patients who had pulmonary thromboembolism or acute coronary syndrome during the acute period of the disease, patients who had an ejection fraction of the LV <50%, patients who were diagnosed with pericarditis during acute illness or clinical signs of heart failure (or had elevated N-terminal-pro hormone B-type natriuretic peptide value), with verified renal or hepatic dysfunction were excluded from the study, including patients with diabetes mellitus Type 1, patients with cancer, connective tissue disease, or pregnant women. The existence of cardiovascular risk factors (hypertension, diabetes mellitus Type 2, and hyperlipidemia), the presence of previous ischemic heart disease, maximum values of D-dimer, and CRP (during the first 15 days of the disease) was taken into the analysis. Results Effusion was verified around the right atrium (RA) in 104 patients (3.85 ± 1.75 mm), in 135 patients next to the free wall of the right ventricle (RV) (5.24 ± 2.29 mm), in front of the apex of the LV in 27 patients (2.44 ± 0.97 mm), next to the lateral wall of LV in 35 patients (4.43 ± 3.21 mm), and behind the posterior wall of LV in 30 patients (2.83 ± 1.62 mm). Mean CRP values during the acute phase of the disease were 43.0 mg/L (8.6–76.2 mg/L), whereas D-dimer mean value was 880.00 μg/L (467.00 –2000.00 μg/L). CRP values correlated with effusion next to the free wall of RV (rho = 0.202; P = 0.018). The D dimer correlated with effusion around RA (rho = 0.308; P = 0.0001). Conclusion The clinical picture of the post-COVID patients could be explained by the appearance of pericardial effusion. D-dimer value correlates with the occurrence of effusion around RA, whereas CRP value correlates with effusion next to the free wall of RV.

Ivona Šušak, Vedran Bjelanović, Dejan Tirić, V. Tomić

Background: The aim of this study was to determine and analyze the frequency and obstetric features of preterm birth and neonatal outcomes of infants born before 37 completed weeks of pregnancy. Methods: The retrospective study included 470 premature births. The following data on preterm births were collected from hospital records and analyzed: gestational age, type of preterm birth, multiple pregnancy and maternal parity. The parameters of preterm infants were: Apgar score, intrauterine growth restriction (IUGR), perinatal asphyxia, respiratory distress syndrome (RDS), sepsis, necrotizing enterocolitis, intracranial hemorrhage, neonatal convulsions, hypoglycemia, blood transfusion, the need for surfactant, the need for mechanical ventilation, the length of stay in an Intensive Care Unit and early and late neonatal mortality.Main findings: The frequency of preterm births was 6.48%. The most common type of premature birth was spontaneous premature birth. Most complications occurred in neonates with a gestational age of 28-34 weeks. The most common respiratory complication was RDS (8.1%). Early neonatal mortality was 1.49% and late neonatal mortality was 0.85%.Principal conclusion: Neonatal outcomes of premature infants are directly proportional to their gestational age. The neonatal mortality rate of premature infants at Clinical Hospital Center Mostar (CHC) Mostar is comparable to other developing countries.Key words: preterm birth, gestational age neonatal outcome, perinatal care, neonatal mortality

By using various sports recreation programs, we try to reduce the negative effects of living in today's age. This study defines a sports-recreational program based on athletic throwing exercises. The reduced amount of muscle mass that comes with age and thus the deficit of strength, coordination and balance cause difficulty in movement and the inability to perform harmonious movements. The decline in motor skills that comes at the time of involution can be quite slowed down through recreational programs that target these abilities. Considering that sports recreation is in question, the intensity and scope of action is logically significantly less than competitive training. In addition to the basic disciplines of shot put, discus throw, javelin throw, and hammer throw, the recreational program also used a large number of exercises that throwers use in their training as ancillary exercises as well as exercises with free weights. The aim of this paper is to emphasize the importance of recreational exercise and health and the wider sports and recreational content of athletic throwing.

Lejla Hadžikadić-Gušić, T. Cerić, I. Marijanović, Ermina Iljazović, Dijana Koprić, Anela Zorlak, Mahira Tanović, A. Mekić-Abazović et al.

Breast cancer is the most common cancer among women. In Bosnia and Herzegovina (BiH), accurate data on the status of breast cancer are lacking due to the absence of a central registry. Multiple international guidelines imply that institutions that monitor breast cancer patients should have optimal therapeutic options for treatment. In addition, there have been several international consensus guidelines written on the management of breast cancer. Application of consensus guidelines has previously been demonstrated to have a positive influence on breast cancer care. The importance of specialty breast centers has previously been reported. As part of the 2021 Bosnian-Herzegovinian American Academy of Arts and Sciences (BHAAAS) conference in Mostar, a round table of multidisciplinary specialists from BiH and the diaspora was held. All were either members of BHAAAS or regularly participate in collaborative projects. The focus of the consortium was to write the first multidisciplinary guidelines for the general management of breast cancer in BiH. Guidelines were developed for each area of breast cancer treatment and management. These guidelines will serve as a resource for practitioners managing breast cancer in the BiH region. This might also be of benefit to the ministry of health and any future investors interested in developing breast cancer care policies in this region of the world.

Duško Tešić, Marko Radovanović, Darko Božanić, D. Pamucar, A. Milic, Adis Puška

This study considers the problem of selecting an anti-tank missile system (ATMS). The mentioned problem is solved by applying a hybrid multi-criteria decision-making model (MCDM) based on two methods: the DIBR (Defining Interrelationships Between Ranked criteria) and the MABAC (Multi-Attributive Border Approximation area Comparison) methods. The methods are modified by applying rough numbers, which present a very suitable area for considering uncertainty following decision-making processes. The DIBR method is a young method with a simple mathematical apparatus which is based on defining the relation between ranked criteria, that is, adjacent criteria, reducing the number of comparisons. This method defines weight coefficients of criteria, based on the opinion of experts. The MABAC method is used to select the best alternative from the set of the offered ones, based on the distance of the criteria function of every observed alternative from the border approximate area. The paper has two main innovations. With the presented decision-making support model, the ATMS selection problem is raised to a higher level, which is based on a proven mathematical apparatus. In terms of methodology, the main innovation is successful application of the rough DIBR method, which has not been treated in this way in the literature so far. Additionally, an analysis of the literature related to the research problem as well as to the methods used is carried out. After the application of the model, the sensitivity analysis of the output results of the presented model to the change of the weight coefficients of criteria is performed, as well as the comparison of the results of the presented model with other methods. Finally, the proposed model is concluded to be stable and multi-criteria decision-making methods can be a reliable tool to help decision makers in the selection process. The presented model has the potential of being applied in other case studies as it has proven to be a good means for considering uncertainty.

W. Yan, Wanming Hao, Chongwen Huang, Gangcan Sun, O. Muta, H. Gačanin, Chau Yuen

Reconfigurable intelligent surface (RIS)-aided terahertz (THz) communications have been regarded as a promising candidate for future 6G networks because of its ultra-wide bandwidth and ultra-low power consumption. However, there exists the beam split problem, especially when the base station (BS) or RIS owns the large-scale antennas, which may lead to serious array gain loss. Therefore, in this paper, we investigate the beam split and beamforming design problems in the THz RIS communications. Specifically, we first analyze the beam split effect caused by different RIS sizes, shapes and deployments. On this basis, we apply the fully connected time delayer phase shifter hybrid beamforming (FC-TD-PS-HB) architecture at the BS and deploy distributed RISs to cooperatively mitigate the beam split effect. We aim to maximize the achievable sum rate by jointly optimizing the hybrid analog/digital beamforming, time delays at the BS and reflection coefficients at the RISs. To solve the formulated problem, we first design the analog beamforming and time delays based on different RISs’ physical directions, and then it is transformed into an optimization problem by jointly optimizing the digital beamforming and reflection coefficients. Next, we propose an alternatively iterative optimization algorithm to deal with it. Specifically, for given the reflection coefficients, we propose an iterative algorithm based on the minimum mean square error technique to obtain the digital beamforming. After, we apply Lagrangian dual reformulation (LDR) and multidimensional complex quadratic transform (MCQT) methods to transform the original problem to a quadratically constrained quadratic program, which can be solved by alternating direction method of multipliers (ADMM) technique to obtain the reflection coefficients. Finally, the digital beamforming and reflection coefficients are obtained via repeating the above processes until convergence. Simulation results verify that the proposed scheme can effectively alleviate the beam split effect and improve the system capacity.

E. Kadušić, N. Zivic, C. Ruland, Narcisa Hadzajlic

With the emerging Internet of Things (IoT) technologies, the smart city paradigm has become a reality. Wireless low-power communication technologies (LPWAN) are widely used for device connection in smart homes, smart lighting, mitering, and so on. This work suggests a new approach to a smart parking solution using the benefits of narrowband Internet of Things (NB-IoT) technology. NB-IoT is an LPWAN technology dedicated to sensor communication within 5G mobile networks. This paper proposes the integration of NB-IoT into the core IoT platform, enabling direct sensor data navigation to the IoT radio stations for processing, after which they are forwarded to the user application programming interface (API). Showcasing the results of our research and experiments, this work suggests the ability of NB-IoT technology to support geolocation and navigation services, as well as payment and reservation services for vehicle parking to make the smart parking solutions smarter.

A. Vinković, Gennadiy Laptyev, G. Yaprak, K. Slavova, D. Joksimović, T. Troskot-Čorbić, M. Frontasyeva, O. Duliu et al.

R. Herwig, K. Erlbacher, Amela Ibrahimagic, Mehtap Kaçar, Naime Brajshori, Petrit Beqiri, J. Greilberger

Background: Vitamin D3 complexed to deglycosylated vitamin D binding protein (VitD-dgVDBP) is a water-soluble vitamin D dimeric compound (VitD-dgVDBP). It is not clear how VitD-dgVDBP affects circulating monocytes, macrophages, other immune cell systems, including phagocytosis and apoptosis, and the generation of reactive oxygen species (ROS) compared to dgVDBP. Methods: Flow cytometry was used to measure superoxide anion radical (O2*−) levels and macrophage activity in the presence of VitD-dgVDBP or dgVDBP. VitD-dgVDBP was incubated with normal human lymphocytes (nPBMCs), and several clusters of determination (CDs) were estimated. dgVDBP and VitD-dgVDBP apoptosis was estimated on malignant prostatic cells. Results: The macrophage activity was 2.8-fold higher using VitD-dgVDBP (19.8·106 counts) compared to dgVDBP (7.0·106 counts), but O2*− production was 1.8-fold lower in favor of VitD-dgVDBP (355·103 counts) compared to dgVDBP (630·106 counts). The calculated ratio of the radical/macrophage activity was 5-fold lower compared to that of dgVDBP. Only VitD-dgVDBP activated caspase-3 (8%), caspase-9 (13%), and cytochrome-C (11%) on prostatic cancer cells. PE-Cy7-labeled VitD-dgVDBP was found to bind to cytotoxic suppressor cells, monocytes/macrophages, dendritic and natural killer cells (CD8+), and helper cells (CD4+). After 12 h of co-incubation of nPBMCs with VitD-dgVDBP, significant activation and expression were measured for CD16++/CD16 (0.6 ± 0.1% vs. 0.4 ± 0.1%, p < 0.05), CD45k+ (96.0 ± 6.0% vs. 84.7 ± 9.5%, p < 0.05), CD85k+ (24.3 ± 13.2% vs. 3.8 ± 3.2%, p < 0.05), and CD85k+/CD123+ (46.8 ± 8.1% vs. 3.5 ± 3.7%, p < 0.001) compared to the control experiment. No significant difference was found using CD3+, CD4+, CD8+, CD4/CD8, CD4/CD8, CD16+, CD16++, CD14+, or CD123+. A significant decline in CD14+/CD16+ was obtained in the presence of VitD-dgVDBP (0.7 ± 0.2% vs. 3.1 ± 1.7%; p < 0.01). Conclusion: The newly developed water-soluble VitD3 form VitD-dgVDBP affected cytotoxic suppressor cells by activating the low radical-dependent CD16 pathway and seemed to induce apoptosis in malignant prostatic cells.

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