Dimljeni mesni proizvodi čine jednu od najvažnijih skupina tradicionalnih namirnica. Zahvaljujući jedinstvenim i povoljnim organoleptičkim svojstvima te visokoj kvaliteti, potrošači ih rado biraju. U posljednje vrijeme raste zabrinutost oko zdravstvenih aspekata ovih proizvoda. Istraživanja sugeriraju da tradicionalno dimljeni mesni proizvodi mogu biti povezani s nekim problemima zdravstvene sigurnosti, poput prisutnosti policikličkih aromatskih ugljikovodika (PAH). Policiklički aromatski ugljikovodici predstavljaju veliku skupinu kemijskih spojeva prepoznatu kao mogućeg uzročnika nastanka malignih oboljenja a mogu nastati tijekom toplinske obrade hrane tradicionalnim postupcima kao što su sušenje i dimljenje. Postoje različiti mehanizmi nastanka PAH-a, pri čemu svi spojevi koji sadrže ugljik i vodik mogu poslužiti kao prekursori nastanka PAH-ova Tijekom reakcija nastanka PAH-a, vodik i ugljik spajaju se u ciklički spoj s izmjeničnim jednostrukim i dvostrukim vezama, s dva ili više kondenziranih aromatskih prstenova, koji daju visok karcinogeni i mutageni potencijal.Stoga je cilj ovog istraživanja bio analizirati čimbenike koji utječu na kvalitetu i zdravstvenu ispravnost tradicionalnih mesnih proizvoda u pogledu sadržaja policikličkih aromatskih ugljikovodika na temelju dostupne literature.

We prove a master identity for a class of sequences defined by full-history linear homogeneous recurrences with (non-negative) constant coefficients. The identity is derived in a combinatorial way, providing thus combinatorial proofs for many known and new identities obtained as its corollaries. In particular, we prove several interesting identities for the Pell, the Jacobsthal, and the m -nacci numbers.

Placental insufficiency is a common cause of intrauterine growth restriction (IUGR). It affects ~10% of pregnancies and increases fetal and neonatal morbidity and mortality. Although Wnt and Hh pathways are crucial for embryonic development and placentation, their role in the pathology of IUGR is still not sufficiently explored. The present study analyzed the expression of positive regulators of the Wnt pathway, WNT5A and β-catenin, and the expression of the Hh pathway negative regulator suppressor of fused (SUFU). Immunohistochemical and reverse transcription-quantitative PCR (RT-qPCR) assays were performed on 34 IUGR and 18 placental tissue samples from physiologic singleton-term pregnancies. Epigenetic mechanisms of SUFU gene regulation were also investigated by methylation-specific PCR analysis of its promoter and RT-qPCR analysis of miR-214-3p and miR-378a-5p expression. WNT5A protein expression was higher in endothelial cells of placental villi from IUGR compared with control tissues. That was also the case for β-catenin protein expression in trophoblasts and endothelial cells and SUFU protein expression in trophoblasts from IUGR placentas. The SUFU gene promoter remained unmethylated in all tissue samples, while miR-214-3p and miR-378a-5p were downregulated in IUGR. The present results suggested altered Wnt and Hh signaling in IUGR. DNA methylation did not appear to be a mechanism of SUFU regulation in the pathogenesis of IUGR, but its expression could be regulated by miRNA targeting.

The coronavirus disease 2019 (COVID19) pandemic continues to represent a substantial public health concern. It can rapidly progress to severe disease, with poor prognosis and a high mortality risk. An early diagnosis and specific prognostic tools can help healthcare providers to start interventions promptly, understand the likely prognosis and to identify and treat timely individuals likely to develop severe disease with enhanced mortality risk. Here we focused on an impressive set of systematic reviews and meta-analyses that were performed since the start of the COVID19 pandemic and summarized their results related to the levels of hematologic, inflammatory, immunologic biomarkers as well as markers of cardiac, respiratory, hepatic, gastrointestinal and renal systems and their association with the disease progression, severity and mortality. The evidence outlines the significance of specific biomarkers, including inflammatory and immunological parameters (C-reactive protein, procalcitonin, interleukin-6), hematological (lymphocytes count, neutrophil-to-lymphocyte ratio, D-dimer, ferritin, red blood cell distribution width), cardiac (troponin, CK-MB, myoglobin), liver (AST, ALT, total bilirubin, albumin) and lung injury (Krebs von den Lungen-6) that can be used as prognostic biomarkers to aid the identification of high-risk patients and the prediction of serious outcomes, including mortality, in COVID19. Thus, these parameters should be used as essential tools for an early risk stratification and adequate intervention in improving disease outcomes in COVID19 patients.

Background Pandemics, such as COVID-19, are dangerous and socially disruptive. Though no one is immune to COVID-19, older persons often bear the brunt of its consequences. This is particularly true for older women, as they often face more pronounced health challenges relative to other segments in society, including complex care needs, insufficient care provisions, mental illness, neglect, and increased domestic abuse. To further compound the situation, because protective measures like lockdowns can result in unintended consequences, many health services older women depend on can become disrupted or discontinued amid pandemics. While technology-based interventions have the potential to provide near-time, location-free, and virtually accessible care, there is a dearth of systematic insights into this mode of care in the literature. To bridge the research gaps, this investigation aims to examine the characteristics and effectiveness of technology-based interventions that could address health challenges older women face amid COVID-19. Methods A systematic review of randomized trials reporting on technology-based interventions for older women (≥65 years) during COVID-19 will be conducted. The databases of Web of Science, ScienceDirect, PubMed/MEDLINE, PsycINFO, CINAHL, and Scopus will be searched. Retrieved citations will be screened independently by at least two reviewers against the eligibility criteria. Included studies will be assessed using the Cochrane ROB-2 tool. Data will be extracted independently by the reviewers. Where possible, meta-analyses will be performed on relevant study outcomes and analysed via odds ratios on the dichotomized outcomes. Where applicable, heterogeneity will be measured using the Cochrane Q test, and publication bias will be assessed via funnel plots and Egger’s regression test. Discussion Technology has the potential to transform healthcare for the better. To help society better safeguard vulnerable populations’ health and quality of life, this investigation sets out to gauge the state-of-the-art development of technology-based interventions tailored to the health challenges older women face amid COVID-19. In light of the growing prevalence of population ageing and the inevitability of infectious disease outbreaks, greater research efforts are needed to ensure the timely inception and effective implementation of technology-based health solutions for vulnerable populations like older women, amid public health crises like COVID-19 and beyond. Systematic review registration PROSPERO CRD42020194003

This paper raises a discussion on innovation, nature of knowledge and the growing significance of skills in contemporary society. We propose the argument that knowledge is commonly perceived in terms of skills only, as a result of an applicability logic rule in knowledge based social orders. Moreover, innovation is recognized as yet another central issue of our times that is strongly interrelated to technological developments and the realm od science. Creativity as a specific human feature, on the other hand, is widely accepted as a critical precondition for generating innovative products and ideas. The essential problem lies in the oversight of the role humanities and arts play in nurturing humanistic values, whereas means are commonly mistaken for an end.

Introduction: Today, a lot is said and written about the hospital as a health institution. Various international bodies and organizations, including the World Health Organization, deal with the problem of work, functions, and organizations.Aim: This paper aims to perform a situational analysis of the organization of the hospital for emergencies; determine the availability of material and personnel resources in the hospital available in emergencies; examine the types of hazards that may have an impact on the safety of the hospital; determine the state of constructive and non-constructive safety of the hospital; examine the organization of services and support for patients and staff during emergencies.Methods: The research is descriptive and analytical. Standardized evaluation lists prescribed by the World health organization (WHO), which determines the hospital safety index, and the original survey questionnaire, according to the defined methodology of the WHO, were used as research instruments.Research results: For this work, a survey was conducted of 117 respondents, employees of the Clinical Center of the University of Sarajevo, who work in responsible positions. The majority of respondents believe that the conditions for preparing the hospital for emergencies can be improved by providing more human resources, educating staff, and ensuring important modern technologies. The situational analysis at the Clinical Center of the University of Sarajevo was carried out with an internal self-assessment of the hospital's safety index. The evaluation of the safety index for emergencies was calculated based on the defined WHO methodology.Conclusion: It is important to point out that there are many dangers (hazards) that can have an impact on the safety of hospitals and that different factors have a significant role in the preparedness of hospitals for an emergency or disaster.

The movie mother! is a psychological horror movie, written and directed in 2017 by Darren Aronofsky. The plot of the movie revolves around a couple living in an isolated house, as their serene lives become thrown into disarray by a series of bizarre events started by the arrival of a mysterious couple and many other strange guests. This movie is known for its representation of biblical symbolism, with underlying warnings of the inevitable self-destruction of human race through their historically repetitive torment of Mother Earth.The main topic of this article is going to be an analysis of the symbolic milieu of the movie, with special attention to the depiction of power dynamics of the represented (divine) feminine and masculine, as well as power relations of the characters, in general. In that process, we hope to understand the stages of their transformation, with regards to the question of the nature of their transformation - was it social or structural? Interpretation of the transformation and its nature, we also contemplate the nature of recognized process of othering in the movie, that relies on the root of the recognized power relations? All of these questions are explored through interpretation of symbolic communication, in which the architectural setting acts as a character "anchor" and a sustenance for its development, as well as the indicator and medium of its transformation.

Transmit power control is one of the most important issues in wireless networks, where nodes typically operate on limited battery power. Reducing communicating power consumption is essential for both economic and ecologic reasons. In fact, transmitting at unnecessarily high power not only reduces node lifetime, but also introduces excessive interference and electromagnetic pollution. Existing work in the wireless community mostly focus on designing transmit power policies by taking into account communication aspects like quality of service or network capacity. Wireless networked control systems (WNCSs), on the other hand, have different and specific needs such as stability, which require transmit power policies adapted to the control context. Transmit power design in the control community has recently attracted much attention, and available works mostly consider linear systems or specific classes of non-linear systems with a single-link view of the system. In this paper, we propose a framework for the design of stabilising transmit power levels that applies to much larger classes of non-linear plants, controllers, and multi-link setting. By exploiting the fact that channel success probabilities are related to transmit power in a non-linear fashion, we first derive closed-loop stability conditions that relate channel probabilities with transmission rate. Next, we combine these results together with well-known and realistic interference models to provide a design methodology for stabilising transmit power in non-linear and multi-link WNCSs.

Oxytocin (OT) has a well‐established role in reproductive behaviours; however, it recently emerged as an important regulator of energy homeostasis. In addition to central nervous system (CNS), OT is found in the plasma and OT receptors (OT‐R) are found in peripheral tissues relevant to energy balance regulation. Here, we aim to determine whether peripheral OT‐R activation is sufficient to alter energy intake and expenditure.

Based on the available archival material and additional literature, this paper approaches the analysis of the textbooks of the Bosnian Franciscans Ambroža Matić and Augustin Miletić from the sociolinguistic aspect in the context of language naming and linguistic identity. The textbooks serve as examples from the corpus of our initial textbook literature referring to the early period or the very beginning of the contemporary (more modern) type of public schooling in Bosnia and Herzegovina, with the aim of looking at identitarian language issues closely related to the issue of national identity. The starting point is the curriculum of the state (Franciscan) primary school in Tolisa (Orašje) from 1823, on the basis of which we can speak of a significant jubilee that today marks two centuries of a particularly important tradition: the official Bosnian language at the beginning (in the early period) of modern public schooling in Bosnia and Herzegovina. Furthermore, the paper shall analyze textbooks from the beginning of the 19th century, at a time when the processes of nationalization and significant mutual identitarian alienation of the local population had not yet taken root.

The problem of social exclusion is in the expert and scientific community known as one of the leading social problems of the modern world. Social exclusion becomes massive and troublesome process which warns that in the society faces serious changes that can have long-lasting and severe consequences on individuals and groups. This article consider the position civilian victims of war in Canton Sarajevo for some time presenting empirical research results, which is made by test method, elaborating the thesis that this is vulnerable population socially excluded from all segments of social life and on the scale of the problem social exclusion from cultural, social, economic and political life.