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Malik Jakirlić, Sanela Salihagic, Nedim Katica, Vanis Dujso

Background: Compression of the ulnar nerve at the level of Guyon’s canal is a very rare compressive neuropathy. Due to the vast range of symptoms that can manifest depending on the degree of ulnar nerve compression, the clinical picture is not consistent. Objective: The aim of the study is to outline the diagnostic techniques and therapeutic options. Case report: We reported a case of ganglion cyst-induced compression of the ulnar nerve in Guyon’s canal. A 45-year-old female patient underwent surgical ulnar nerve release in Guyon’s canal at the Clinic for Plastic and Reconstructive Surgery. Discussion: After a thorough medical history and physical examination, the diagnosis of the syndrome is made, and ultrasound and magnetic resonance imaging (MRI) testing are used to determine the origin of the neuropathy. A ganglion cyst was identified pathohistological one month following the surgical excision of the soft tissue tumor. In order to hasten the patient’s nerve recovery, physical therapy was recommended, and the patient was monitored for the following two years. After two years of treatment, the patient has made a very good recovery of the functionally damaged hand, as determined by a modified Bishop scoring method for evaluating functional ulnar nerve recovery. Conclusion: In virtually all cases, early surgical intervention can lead to an outstanding functional recovery. If the symptoms are more severe and continue or get worse for more than three months, early surgical intervention is the gold standard for treating Guyon’s canal syndrome. If soft tissue formations are compressing the ulnar nerve in Guyon’s canal, MRI is thought to be the gold standard for diagnosis.

Background: Psoriasis as an immune-mediated inflammatory skin disease. The basis of the pathogenesis of psoriasis is the dysregulation of immune cell function in genetically predisposed individuals. The characteristic dysfunction of the immune system in patients with psoriasis is manifested as a variation in the cellular phenotypic profile in accordance with the disease status. Objective: The aim of this study was to evaluate the immunophenotypic profile of lymphocytes obtained by flow cytometry as an auxiliary diagnostic tool in the objectivization of the PASI score. Methods: The study group included 40 patients with psoriasis, hospitalized and treated at Dermatology Clinic of Clinical center University of Sarajevo and 30 healthy individuals as controls. After venepunction, the blood samples for determining the immune profile were prepared following standard laboratory procedures using conjugated monoclonal antibodies and BD FACSCanto II flow cytometer. T-lymphocytes (CD3, CD4, CD8), B lymphocytes (CD19), Natural killer cells (NK), and activatet T-cells (CD3HLA) were determined for all patients. Based on the PASI score, the severity and area of the disease was assessed for all psoriasis patients by dermatology specialist. Results: Our data shows no significant difference in any of the lymphocyte subpopulations between psoriasis patients and healthy controls, except CD3HLA. CD3HLA has higher values in patients with psoriasis, p=0.015. Of all the parameters, only NK cells were significantly correlated to the PASI score (rho -0.279; p=0.048). ROC curve analysis revealed a statistically significant difference for the proportion of CD3 lymphocytes (AUC 0.799; p=0.004), CD8 lymphocytes (AUC 0.733; p= 0.023), NK cells (AUC 0.722; p=0.008) and CD3HLA activated T lymphocytes (AUC 0.347; p=0.034). Conclusion: Profile of major lymphocyte subsets in patients with psoriasis is similar to that of healthy controls. The values of CD3, CD8, NK, CD3HLA were defined as biomarkers capable of distinguishing psoriasis according to the severity of the disease. Immunophenotyping of peripheral blood lymphocytes can play an important role as an auxiliary diagnostic method in differentiating the clinical stages of psoriasis and objectifying the PASI score.

R. Hasanagić, Leila Fathi, Atif Hodžić, M. Bahmani

In Europe, wood is a crucial construction material that has experienced a surge in use for building applications in recent years. To enhance its dimensional stability and durability, thermal modification is a widely accepted commercial technology. Thermal modification is a popular technique that alters the properties of wood, improving its resistance to decay and increasing its dimensional stability. The process involves heating wood to high temperatures under controlled conditions, leading to chemical reactions that result in various physical and mechanical changes. This paper will discuss the effects of thermal modification on the physical properties of wood, such as density, moisture content, and color, as well as its impact on the mechanical properties, including strength, stiffness, and hardness. Additionally, the review will examine the factors that influence the degree of modification, such as temperature, duration, and wood species. Finally, the paper will conclude with an overview of the current state of research in this field and identify potential avenues for future investigation.

Demiao Chu, R. Hasanagić, Leila Fathi, M. Bahmani, M. Humar

This study aimed to investigate the water absorption capacity of thermally modi fi ed and non-modi fi ed spruce and blue-stained spruce wood. The wettability of wood depends on various factors, including its type, density, porosity, and surface treatment. Wood can swell and become distorted when exposed to water or humidity, impacting its structural integrity. Hence, it is crucial to consider the water and water vapour uptake in the wood when choosing materials for applications that are likely to be exposed to moisture. Various moisture absorption tests were conducted to assess water absorption capacity, including short-term and long-term water absorption and water vapour absorption. The results showed a signi fi cant difference in the long-term exposure to water, which was related to the density of the wood. The study examined the in fl uence of thermal treatment on the physical properties of wood and observed signi fi cant variations in mass change due to coating, indicating differences in adhesion among different wood types. Vacuum-treated blue-stained Norway spruce demonstrated higher adhesion (5% – 15%) compared to air-treated samples. Furthermore, cohesion tests revealed lower cohesion force in blue-stained Norway spruce (approximately 20% – 30%) compared to Norway spruce. The study also used indus-try-standard tests to investigate the adhesion and cohesion of nano-coatings on wood surfaces. The results provided valuable information on the properties of coatings applied to wood, which is vital in protecting and decorating wood while also providing preventive protection against wood pests, weathering, and mechanical in fl uences. Wood modi fi cation in vacuum involves subjecting the wood to a low-pressure environment to remove air and moisture, allowing for deeper and more uniform penetration of treatment chemicals. In contrast, wood modi fi cation in air relies on the natural circulation of air to facilitate the absorption of chemical treatments, without the need for a vacuum chamber.

Current trends in educational sciences can best be evaluated by assessing the master and doctoral theses defended at the universities. The goal of the present paper was to do a qualitative content analysis of the titles of master theses defended at the Faculty of Educational Sciences at the University of Sarajevo, Bosnia and Herzegovina. Total of 393 master theses defended in the period from 2012 to 2021 were the subject of this analysis. Of these, 287 were defended at the department for teacher education and 106 at the department for preschool education. As expected, most of the studies dealt with early elementary school students and preschool children. Many studies contained the term “development” in its title, and it was referring to all domains from speech to socio- emotional and motor development. Several studies examined parental and teachers’ attitudes towards various topics. In relation to the subject, most studies dealt with science education, followed by physical education and language. A number of studies had special education as the main topic, covering issues of teacher competencies, creativity, support to students with developmental disabilities, to the quality of life. Students have studied various relevant topics. In the future, we expect to see an increase in studies covering digital competencies of teachers and evaluation of online education.

The aim of this research is to analyze the spatial distribution of the population ageing in Bosnia and Herzegovina and identify areas of the country that are particularly vulnerable to negative demographic trends. To achieve the goal of the study, data on the ageing coefficient and ageing index for the period 2013-2020 were used. The geospatial analysis of these indicators was performed using global (Global Moran's I and Getis-Ord General G) and local (Anselin Local Moran's I and Getis-Ord G*) indexes of spatial autocorrelation. The research results confirmed the clustering of both indicators. Ageing coefficient values are clustered in municipalities in western, northwestern, Eastern, and central Bosnia and Herzegovina. Ageing index values are clustered in municipalities in central, western, northwestern, and northeastern Bosnia and Herzegovina. This study provides insight into the research methods of spatial demographic trends and phenomena, and its findings can serve as a basis for future demographic research and development in Bosnia and Herzegovina.

The acute scrotum (AS) in the pediatric population is a medical emergency. AS is usually caused by testicular torsion (TT) and torsion of the appendix testis (TAT). The current study explored which demographic and clinical characteristics can help distinguish between TT and TAT. We analyzed all children ≤16 years who underwent surgical exploration for AS. The patients were divided into Group 1/TT and Group 2/TAT. Ninety patients were included in the study (24 with TT and 66 with TAT). The peak incidence of TT was significantly higher than in the TAT group (p<0.001). Scrotal pain was more prevalent in the TAT group (p=0.02), whereas systemic signs (nausea/vomiting and abdominal pain) affected more frequently the TT patients (p=0.003 and p<0.001, respectively). The duration of symptoms was significantly longer in the TAT group (p<0.001). The duration of symptoms in the TT cohort significantly impacted the testicular salvage (p=0.008). Color Doppler ultrasound (CDUS) findings of absent/decreased testicular blood flow in the affected testis strongly favored the diagnosis of TT (p<0.001). The older age, shorter duration of symptoms, systemic signs, and CDUS findings can help distinguish between the two most common acute scrotum causes.

The World Health Organization (WHO) released guidelines for physical activity, sedentary behav-iour, and sleep for children under 5 years of age in 2019. In response to these guidelines, this study aimed to determine the proportion of preschool children (ages 3-5 years) who met the WHO guidelines. The time spent in physical activity, sedentary behaviour and sleep were objectively measured using accelerometer (ActiGraph wGT3x-BT). Screen time and sleep quality were assessed via parent questionnaire. Focus groups were con-1 ducted with parents and childcare staff to determine the feasibility of the protocol. The results showed that only 23% of the children met all three guidelines, and compliance rates varied for each guideline. The physical activity time guideline was met by 64% of children, the sleep duration guideline was met by 74% of children, and the screen time guideline was met by 53% of children. Only a low proportion of children met the WHO guidelines. The methods and devices used in this pilot study proved to be feasible and this has paved the way to conduct the main SUNRISE study in Bosnia and Herzegovina.

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