The surveillance system has been utilized over the years on public property in order to provide security and prevent unauthorized entrance. Lately, more private homeowners are choosing to implement security systems. There are many problems with the video surveillance system. These disadvantages are the indistinctiveness of the pictures/video and the need for a lot of storage space to save surveillance information. This paper describes the design and implementation of a low-cost Web Monitoring System based on Raspberry Pi. Also, a web application is designed for the purposes of controlling the camera and for live streaming. The live stream from a web camera can be viewed from any web browser, even mobile, in real-time. Controlling the camera is possible with the web application using four commands (up/down, left/right). Also, the camera moves depending on the detection of an object located in the visible area of the PIR Motion sensor, thereby issuing a warning message about object detection.

Bilateral teleoperation has attracted significant research and application interests in a wide range of areas. The first and main use for bilateral teleoperation was to handle the dangerous and remote distance tasks such as space exploration and nuclear materials manipulation. In the past few years, bilateral teleoperation has found its way into other applications as a result of the development of control technologies and the latest breakthrough in artificial intelligence and machine learning. In this paper, the goal is to model bilateral teleoperation for direct control, PID control, and Fuzzy Logic control for the water tank system. The goal is to create a simulation for master-slave communication where the time delay is minimized to the optimal and accepted values. The experimental results obtained from the simulation show a fairly high accuracy in terms of all three ways of control modes, which highlights the effectiveness of the proposed system in the paper.

The unification of quantum mechanics and general relativity has long been elusive. Only recently have empirical predictions of various possible theories of quantum gravity been put to test, where a clear signal of quantum properties of gravity is still missing. The dawn of multi-messenger high-energy astrophysics has been tremendously beneficial, as it allows us to study particles with much higher energies and travelling much longer distances than possible in terrestrial experiments, but more progress is needed on several fronts. A thorough appraisal of current strategies and experimental frameworks, regarding quantum gravity phenomenology, is provided here. Our aim is twofold: a description of tentative multimessenger explorations, plus a focus on future detection experiments. As the outlook of the network of researchers that formed through the COST Action CA18108 ‘Quantum gravity phenomenology in the multi-messenger approach (QG-MM)’, in this work we give an overview of the desiderata that future theoretical frameworks, observational facilities, and data-sharing policies should satisfy in order to advance the cause of quantum gravity phenomenology.

The lower limb prosthesis, as the specific object of this biomechanical research, has the task of restoring the normal function of the missing part of the human body. Creating a prosthesis exclusively for the end user is a very complex process. The subject of analysis in this work is the analysis of forces, deformations and stress state on the example of structural elements of the lower prosthetic device with the aim of understanding the integrity of the structure under the action of variable load. This analysis is one of the bases for the overall approach to the design of prosthetic aids for the end user, and especially the creation of the socket, as the most important element of a prosthesis in contact with man’s residuum. The main goal of this work is to estimate the real value of the load of a complex prosthesis, to understand the effect of the load on the elements of the observed example of construction, and to understand the load transfer on the connection of the prosthesis structure with the socket. After defining the real load values, the performed numerical analysis indicated the critical points of the construction, the need to use more accurate material properties in the “foot” element, and in the “socket” zone, the possibility for corrections of the shape and thickness of the wall.

Uvod: Povećanje koncentracije olova u okolišu posljedica je intenzivne industrijalizacije i urbanizacije. Toksična djelovanja olova zasnivaju se na inhibiciji aktivnosti velikog broja enzima, indukciji oksidativnog stresa i disregulaciji biosinteze proteina. Najčešći put unosa u općoj populaciji je ingestija kontaminirane hrane i vode, dok je inhalatorni put najčešće povezan sa profesionalnom izloženošću u različitim zanimanjima. Cilj istraživanja je evaluirati laboratorijske metode i biomarkere u procjeni izloženosti olovu. Materijal i metode: Za potrebe neeksperimentalnog kvalitativnog istraživanja korišteni su dostupni naučni članci publicirani na engleskom jeziku u relevantnim bazama podataka (MEDLINE i ScienceDirect). Pretraga baza provedena je upotrebom ključnih riječi: „laboratory diagnostics“, „occupational exposure“, „lead“. Rezultati: Najširu primjenu u laboratorijskoj dijagnostici kod procjene profesionalne izloženosti olovu imaju atomska apsorpciona spektrometrija (AAS) kao zlatni standard i induktivno spregnuta plazma sa masenom spektrometrijom, koja se zbog niske granice detekcije opisuje kao senzitivnija metoda u poređenju sa AAS. Koncentracija olova može se odrediti u brojnim biološkim uzorcima, ali se u laboratorijskoj praksi najčešće upotrebljavaju krv i urin. Kao najznačajniji biomarker u praćenju izloženosti koristi se enzim dehidrataza δ-aminolevulinske kiseline (ALAD) u krvi, kojeg karakterizira progresivna inaktivacija olovom i negativna korelacija sa koncentracijom olova. Također, koncentracija delta-aminolevulinske kiseline u urinu (δ-ALA-U) odražava stanje narušene funkcije enzima u biosintezi hema, te se smatra da dodatno određivanje cink protoporfirina u krvi i koproporfirina u urinu značajno doprinose u procjeni poremećaja izazvanih profesionalnom izloženošću olovu. Zaključak: Adekvatno praćenje izloženosti olovu ovisi o dostupnosti i karakteristikama primijenjenih laboratorijskih metoda, te specifičnosti i osjetljivosti biomarkera. Zbog toga, precizno određivanje koncentracije ALAD i δ-ALA-U, uz dodatne biomarkere, postaje imperativ za poboljšanu evaluaciju profesionalne izloženosti i omogućava pravovremeno poduzimanje preventivnih mjera.

Abstract Cancer of the cervix has a progressive character and is one of the most significant public health problems in many countries. Our research aimed to translate EORTC QLQ CX 24 (European Organization for Research and Treatment of Cancer; Quality of life questionnaire-cervical cancer 24) from English to Serbian, to create essential cultural adaptations and to analyze psychometric properties of the translation in a model of female inpatients with cancer of the cervix. The QLQ CX 24 was translated and adapted according to internationally established guidelines, and then tested on a sample of 100 Serbian females with cancer of the cervix. The testing was repeated three times on the same patients. We calculated the internal consistency (Cronbach’s alpha), criterion validity, convergent validity, and discriminative validity of the QLQ CX 24. We used factor analysis to discover the original construct. The Serbian translation of QLQ CX 24 showed good internal consistency, showed satisfactory reliability, and temporal stability. In the first, when was rated by the investigators Cronbach’s alpha was 0.607, and one month later when the questionnaire also was rated by investigators Cronbach’s alpha was 0.696. When the scale was rated by females themselves Cronbach’s alpha was 0.802. Divergent as well as convergent validity tests had good results. The factorial analysis exposed six domains. The Serbian translation of QLQ CX 24 is a trustworthy and appropriate specific instrument for measuring the quality of life in females with cervical cancer.

Increased number of children with autism spectrum disorder (ASD) has also heightened interest in finding and providing appropriate interventions. Early intervention is implemented at the moment when deviations are noticed, without waiting for an official diagnosis. Parents are crucial participants in interventions carried out with children; therefore, this research considers interventions focused on training parents to work with children with ASD up to the age of six. For the purposes of this paper, we searched the following journals: Autism, Focus on Autism and Other Developmental Disabilities, and Research in Autism. The search was limited to editions from 2012 to 2022, and the following keywords were considered: parent training, early intervention, autism. References were searched manually. The initial search yielded a total of 992 articles. Twenty-four studies related to children up to six years old and involving parent training in early intervention were included in the analysis. Using a tool for assessing quantitative studies, the selected studies were evaluated, with each component assessed based on the information contained in the study as good, moderate, or weak. The overall rating for the paper can be strong, moderate, or weak. This paper highlights the importance of support to enhance parental competencies.

Abstract Background Almost 50% of NSCLC patients who initially show a successful response to tyrosine kinase inhibitors targeted therapy (TKI therapy) eventually develop acquired EGFR T790M mutation. The T790M secondary mutation can cause resistance to the targeted therapy and disease relapse. Since this mutation can be present at very low frequencies in liquid biopsy samples, droplet digital PCR (ddPCR), due to its high sensitivity, has opened the possibility for minimally invasive monitoring of the disease during TKI targeted therapy. Materials and methods For this study, a total of 45 plasma samples from NSCLC patients with previously detected EGFR-activating mutations were analyzed. Extracted circulating free DNA was amplified and examined for the presence of T790M mutation using ddPCR technology. For the data analysis, QuantaSoft Software was used. Results Of 45 tested plasma samples, a total of 14 samples were identified as positive for the T790M mutation. The same samples eventually showed the presence of T790M mutation in FFPE. Droplet digital PCR showed its great advantage in high sensitivity detection of rare allele variants. Our ddPCR assay detected T790M mutant allele in frequencies from 0.1%. The average number of droplets generated by ddPCR was 9571. Conclusion Monitoring of the T790M mutation has an important role in the examination of the effects of the prescribed TKI therapy. Since monitoring of potential changes during TKI therapy requires repeated sampling, our results showed that ddPCR technology has made it possible to use liquid biopsy as an adequate minimally invasive alternative for single nucleotide polymorphisms (SNP) detection.

In the past ten years, there has been significant growth in tourism worldwide, including in Bosnia and Herzegovina. The tourism sector is facing a series of challenges and limitations in the general business environment due to the COVID-19 pandemic, as is the entire global economy. The current pandemic has slowed down the growth of world tourism and thus led to the poorer performance of private tourism subjects and an increase in unemployment in the sector. This study aims to analyse the habits of the inhabitants of Bosnia and Herzegovina and the changes in behaviour caused by the COVID-19 pandemic. The two main questions entertained are: whether socio-demographic variables influenced the intention to travel during the COVID-19 pandemic, and whether tourist travel habits influenced the intention to travel during the COVID-19 pandemic. The study uses a quantitative research approach that included data collection through an online survey. The questionnaire link was distributed electronically, via Facebook (social network), and e-mail. The population included in this research are the inhabitants of Bosnia and Herzegovina. The convenience sample included 265 respondents and the research was conducted for one and a half months (from March 2, 2022 to May 17, 2022). The results of the research show that socio-demographic factors influenced the intention to travel during the COVID-19 pandemic and that respondents who own a car would travel more in 2022 than respondents who do not own a car; that respondents aged 31-50 would travel more in 2022 than the older respondents, that respondents who are employed would travel more in 2022 than pensioners, that respondents living in a household of 1-2 members would travel more in 2022 than respondents living in a household of 5 or more members, that respondents with postgraduate studies would travel more in 2022 than respondents with elementary studies only and that respondents with a monthly income of over 2,500 BAM would travel more in 2022 than respondents with monthly income between 500 to 1,500 BAM. The results also show that those respondents who travelled frequently before the COVID-19 pandemic would travel less in 2022 in the context of the current situation of the COVID-19 pandemic.

Uvod: Mišićno-koštani poremećaji uzrokovani radom (engl. Work-Related Musculoskeletal Disorders – WRMSDs) najčešća su oboljenja povezana s radom, a opisuju širok dijapazon degenerativnih i upalnih stanja. WRMSDs pogađaju milione radnika na području cijele Evrope i svijeta, a sami poslodavci zbog njihovih posljedica troše milijarde eura. Zdravstvo kao poseban sektor ima jednu od najvećih prevalenci radom uzrokovanih mišićno-koštanih poremećaja (MKP) u svijetu daleko ispred građevinarstva, rudarstva i proizvodnje. Ispitanici i metode: U istraživanje bilo je uključeno 177 zdravstvenih profesionalca oba spola koji su svojim radom aktivno uključeni u pružanje zdravstvenih usluga, kategorizirani prema životnoj dobi i vrsti radnih zadataka koje obavljaju u različitim položajima tijela u okviru svojih stručnih službi. Instrumenti koji su se koristili u istraživanju su standardizirani holandski upitnik za MKP (Dutch Musculoskeletal Discomfort Questionnaire – DMQ), standardizirani upitnik za procjenu indeksa radne sposobnosti (Work Ability Index – WAI) i ergonomski interventni program. Istraživanje je trajalo od januara 2021. do oktobra 2021. godine. Rezultati: Najveća učestalost MKP povezanih s radom kod zdravstvenih profesionalaca prije i poslije provođenja ergonomskog interventnog programa bila je u području vrata (83,1% prije, 64,9% poslije), u regiji gornjeg dijela leđa (71,8% prije, 56,5% poslije) te u regiji donjeg dijela leđa (68,4% prije, 55,9% poslije). Prosječna vrijednost indeksa radne sposobnosti prije uvođenja ergonomskog interventnog programa iznosila je 35,44±8,59, dok se poslije provedenog ergonomskog interventnog programa statistički signifikantno povećala i iznosila je 38,40±7,30. Zaključak: Ergonomski interventni program je utjecao na smanjenje učestalosti MKP uzrokovanih radom, i povećanje radne sposobnost zdravstvenih profesionalaca.

Cardiovascular diseases (CVDs) are a group of diseases with a very high rate of morbidity and mortality. The clinical presentation of CVDs can vary from asymptomatic to classic symptoms such as chest pain in patients with myocardial infarction. Current therapeutics for CVDs mainly target disease symptoms. The most common CVDs are coronary artery disease, acute myocardial infarction, atrial fibrillation, chronic heart failure, arterial hypertension, and valvular heart disease. In their treatment, conventional therapies and pharmacological therapies are used. However, the use of herbal medicines in the therapy of these diseases has also been reported in the literature, resulting in a need for critical evaluation of advances related to their use. Therefore, we carried out a narrative review of pharmacological and herbal therapeutic effects reported for these diseases. Data for this comprehensive review were obtained from electronic databases such as MedLine, PubMed, Web of Science, Scopus, and Google Scholar. Conventional therapy requires an individual approach to the patients, as when patients do not respond well, this often causes allergic effects or various other unwanted effects. Nowadays, medicinal plants as therapeutics are frequently used in different parts of the world. Preclinical/clinical pharmacology studies have confirmed that some bioactive compounds may have beneficial therapeutic effects in some common CVDs. The natural products analyzed in this review are promising phytochemicals for adjuvant and complementary drug candidates in CVDs pharmacotherapy, and some of them have already been approved by the FDA. There are insufficient clinical studies to compare the effectiveness of natural products compared to approved therapeutics for the treatment of CVDs. Further long-term studies are needed to accelerate the potential of using natural products for these diseases. Despite this undoubted beneficence on CVDs, there are no strong breakthroughs supporting the implementation of natural products in clinical practice. Nevertheless, they are promising agents in the supplementation and co-therapy of CVDs.

We consider the machinability of the material as a technological feature that expresses the ability of the material to remove the maximum number of shavings from its machined surface in the minimum time with satisfactory processing quality, with as little cutting force as possible and as little tool wear as possible. The aim of the experimental research in this work is to examine the significance of the influential kinematic parameters of the roughness of the machined surface, i.e. of wood density (ρ), feeding speed (s’) and the number of spiral cutting knices (z) in the process of planning massive wood on the roughness of the newly created processing surface, which will vary in 14 trials, of which 6 are repetitions in the central point of the compositional plan, where the roughness parameter Ra is obtained as an output value, and the analysis of experimental data from the point of view of possible achievement of a better quality of the processed surface. The obtained mathematical model is essentially applicable and can be used to optimize the machinability parameters in the planning process of solid wood, and the experimental results can be used in further research into other parameters of the machinability of solid wood in the planning process.

Paper presents comparative analysis of experimental and analytical results of mechanical properties on truss members. Deformations are experimentally determined on the model of plexiglass truss, using six strain gauges. Strain gauges are measuring the deformation of truss members at the pre-defined measuring points. Knowing modulus of the elasticity and Hooke’s law, it is possible to calculate the stress values. The experimental stress values will be compared with the values obtained by the software and the results will be analyzed.