Abstract The main aim of this study is to explore the mediating effect of innovation in the relationship between human resource management (HRM) practices and organizational performance. HRM practices are observed through selective hiring, training, participative decision-making, and rewarding. Innovation is conceptualized over behavioral, product, process, and market innovation. The study relies upon the principles of social exchange theory and resource-based theory. Data were collected from 408 managers in an emerging economy context. The proposed conceptual model is evaluated with structural equation modeling using Lisrel 8.8 and SPSS 22. Study findings suggest that innovation influences the relationship between selective hiring, training, and participative decision-making and organizational performance. However, no mediating effect of innovation was found in a relationship between rewarding and organizational business performances. Since human resources and innovation are among the leading sources for building competitive advantage for companies, the study findings contribute to HRM and innovation.

Abstract Banks and banking business are exposed to the influence of numerous risks, of which the importance of credit risk management stands out, because credit risk is the only risk that banks are obliged to measure, record in accounting and report. Banks monitor credit risk through the segmentation of the credit portfolio according to the level of risk. This paper is focused on research related to the management of the riskiest category of the credit portfolio, for which we will use the term special credit risk (SCR) in this paper.

Physical activity is important for the physical and mental health of almost everyone. Nordic walking is a physical activity in which participants use specially designed poles while walking, while the term jogging implies light running at speeds less than 10 km/h. PURPOSE: The aim of this research is to monitor the load intensity in real conditions, using a heart rate monitor Team Polar System, during nordic walking and jogging and comparing possible differences in heart rate responses after the fifth minute of activity, at an average speed of 7.5km/h. METHODS: The assessment of heart rate responses for this research was conducted on the 30 male students, at 2 separate days. RESULTS: The results of the variables used in this study show statistically significant differences at the level of significance p=.000. From the mean value results (M) it is obvious that the respondents achieved higher results of heart rate responses during nordic walking compared to the identical tests applied during jogging. CONCLUSION: The results of this study indicate that both Nordic walking and jogging are beneficial but Nordic walking contributes more in achieving higher body loads resulting in increased oxygen consumption and thus calories Key words: load intensity, heart rate, nordic walking, jogging

Abstract This study classifies local self-government units (local communities) in the Federation of Bosnia and Herzegovina (FBIH) according to socio-economic characteristics by applying the following multivariate methods: principal component analysis (PCA), regression and cluster analysis. The selection of variables was based on literature and adjusted by FBIH specifics, covering the four hypothetical dimensions of regional differentiation: macroeconomic, demographic, infrastructural and socio-cultural indicators. PCA has identified five components: the productivity component, demographic component, component of economic activity potential, spatial component and employment component. Further analysis showed that all identified factors are significant predictors of local communities’ development, measured by the development index. The cluster analysis resulted with four clusters in the FBIH with significant differences in development level. Considering that FBIH municipalities are administrative units of local government and that the classification is based on socio-economic dimensions, identified clusters correspond to the NUTS principles.

Abstract Introduction. COVID-19 pandemic increased consumption of alcohol (including harmful drinking – HD), and decreased physical activity levels (PAL) globally, but there is an evident lack of studies examining the problem in the post-pandemic period. This study aimed to evaluate gender-specific associations between sport participation and PAL (independent variables), and HD (dependent variable) among college/university students during the first post-pandemic year of the COVID-19 pandemic. Material and Methods. The participants were college/university students, aged 18 to 21 years (n = 788; 409 females) from Croatia and Bosnia and Herzegovina. They were tested on socio-demographic factors, HD (using the AUDIT scale), sport participation and PAL (using the IPAQ questionnaire). Analysis of variance, Chi square test, and t-test for independent samples were used to evaluate differences, while logistic regression with dichotomized criterion (HD vs. non-harmful drinking – NHD) was calculated to establish associations between independent and dependent variables. Results. T-test indicated significant differences between HD and NHD in PAL (t-test = 2.16, p = 0.02), but only in males. Also, logistic regression indicated a significant correlation between PAL and HD in males (OR: 1.41, 95%CI: 1.11-1.76), while no association was evidenced: (i) between sport participation and HD (in both males and females), and (ii) between PAL and HD (in females). Conclusions. Results indicated that an overall increase in PAL could be helpful in decreasing HD among college/university students; however, to evaluate it more specifically, prospective analyses are needed.

Flexibility is an important determinant of dynamic balance, but studies rarely examined the chronic effects of flexibility training on changes in balance capacity. This study aimed to determine the influence of different forms of flexibility exercises on dynamic balance in female professional football players. Participants were 30 female professional football players (age =19.0±4.1 years), divided into three groups dynamic stretching group (DSG; N=10, age =18.9±3.3 years), static stretching group (SSG; N=10, age =19.5±4.3 years) and control group (N=10, age =18.5±3.3 years). All groups participated in equal football training, while DSG and SSG performed additional flexibility training 3-times a week (10-15 min of duration) throughout the study course (16 weeks). Dynamic balance was measured by the Y-balance test (YBT), and ANOVA for repeated measurement was applied to identify the effects. Results evidenced the significant influence of both flexibility programs on dynamic balance. Both DSG and SSG were equally effective in the first part of the study (until the 8th week), but between the 8th and 16th study week, only DSG improved their balance capacity significantly. Static stretching should be applied in the first phases of flexibility training aiming at the improvement of dynamic balance, but in later phases, usage of dynamic stretching is suggested.

Background and Objectives: We aimed to assess the effect of AST/ALT ratio on echocardiographic and cardiac magnetic resonance imaging (CMRI) parameters after COVID-19 patients recover. Materials and Methods: 87 patients with COVID-19 were included in the study. The patients were hospitalized with COVID-19 pneumonia, but the patients did not need intensive care unit follow-up or non-invasive mechanical ventilation support. After a discharge and two weeks following the positive swab test result, patients were considered eligible if they had any symptoms. Transthoracic echocardiography (TTE) was performed within 24 h prior to CMRI. The median value of AST/ALT ratio was found, and the study population was divided into two subgroups based on the median AST/ALT ratio value. The clinical features, blood test, TTE and CMRI results were compared between subgroups. Results: C-reactive protein, D-dimer and fibrinogen were found to be significantly higher in patients with high AST/ALT ratio. LVEF, TAPSE, S’, and FAC were significantly lower in patients with high AST/ALT ratio. LV-GLS were significantly lower in patients with high AST/ALT ratio. In CMRI, native T1 mapping signal, native T2 mapping signal and extracellular volume raised significantly in patients with high AST/ALT ratio. Right ventricle stroke volume and right ventricle ejection fraction were significantly lower in patients with high AST/ALT ratio, but right ventricle end systolic volume was significantly higher in patients with high AST/ALT ratio. Conclusion: High AST/ALT ratio is related to impaired right ventricular function parameters with CMRI and echocardiography after recovery from acute COVID-19. Assessment of AST/ALT ratio at hospital admission may be used to assess the risk of cardiac involvement in COVID-19 disease, and these patients may require closer follow-up during and after the course of COVID-19.

Alcohol drinking is an important health-related problem and one of the major risk factors for a wide array of non-communicable diseases, while there is a lack of studies investigating environment-specific associations between sports participation and alcohol drinking in adolescence. This study prospectively investigated the relationship between sports factors (i.e., participation in sports and competitive achievement), with the prevalence of harmful alcohol drinking (HD), and HD initiation in 14-to-16 years old adolescents from Bosnia and Herzegovina (n = 641, 337 females, 43% living in rural community). Participants were tested over 4-time points divided by approximately 6 months, from the beginning of high school to the end of the second grade. Variables included gender, factors related to sport participation, a community of residence (urban or rural), and outcome: alcohol consumption was assessed by the AUDIT questionnaire. Results evidenced that the prevalence of HD increased over the study period from 6 to 19%, with no significant differences between urban and rural youth. Logistic regression for HD as criterion evidenced adolescents who participated in sports and then quit as being at particular risk for drinking alcohol at the study baseline. Sports factors were not correlated with HD initiation in the period between 14 and 16 years of age. It seems that the problem of alcohol drinking should be preventively targeted in all youth, irrespective of living environment. Although sports participation was not evidenced as being a factor of influence on HD initiation, results highlight the necessity of developing targeted preventive campaigns against alcohol drinking for adolescents who quit sports.

Abstract Chronic obstructive pulmonary disease (COPD) and lung cancer (LC) are closely related diseases associated with smoking history and dysregulated immune response. However, not all smokers develop the disease, indicating that genetic susceptibility could be important. Therefore, the aim of this study was to search for the potential overlapping genetic biomarkers, with a focus on single nucleotide polymorphisms (SNPs) located in the regulatory regions of immune-related genes. Additionally, the aim was to see if an identified SNP has potentially an effect on proinflamma-tory cytokine concentration in the serum of COPD patients. We extracted summary data of variants in 1511 immune-related genes from COPD and LC genome-wide association studies (GWAS) from the UK Biobank. The LC data had 203 cases, patients diagnosed with LC, and 360 938 controls, while COPD data had 1 897 cases and 359 297 controls. Assuming 1 association/gene, SNPs with a p-value < 3.3 × 10–5 were considered statistically significantly associated with the disease. We identified seven SNPs located in different genes (BAG6, BTNL2, TNF, HCP5, MICB, NCR3, ABCF1, TCF7L1) to be associated with the COPD risk and two with the LC risk (HLA-C, HLA-B), with statistical significance. We also identified two SNPs located in the IL2RA gene associated with LC (rs2386841; p = 1.86 × 10−4) and COPD (rs11256442; p = 9.79 × 10−3) but with lower significance. Functional studies conducted on COPD patients showed that RNA expression of IL2RA, IFNγ and related proinflammatory cytokines in blood serum did not correlate with a specific genotype. Although results presented in this study do not fully support our hypothesis, it is worth to mention that the identified genes/SNPs that were associated with either COPD or LC risk, all were involved in the activation of the NF-κB transcription factor which is closely related to the regulation of the inflammatory response, a condition associated with both pathologies.

Takotsubo syndrome (TTS) is an acute heart failure syndrome characterised by catecholamine-induced oxidative tissue damage. Punica granatum, a fruit-bearing tree, is known to have high polyphenolic content and has been proven to be a potent antioxidant. This study aimed to investigate the effects of pomegranate peel extract (PoPEx) pre-treatment on isoprenaline-induced takotsubo-like myocardial injury in rats. Male Wistar rats were randomised into four groups. Animals in the PoPEx(P) and PoPEx + isoprenaline group (P + I) were pre-treated for 7 days with 100 mg/kg/day of PoPEx. On the sixth and the seventh day, TTS-like syndrome was induced in rats from the isoprenaline(I) and P + I groups by administering 85 mg/kg/day of isoprenaline. PoPEx pre-treatment led to the elevation of superoxide dismutase and catalase (p < 0.05), reduced glutathione (p < 0.001) levels, decreased the thiobarbituric acid reactive substances (p < 0.001), H2O2, O2− (p < 0.05), and NO2− (p < 0.001), in the P + I group, when compared to the I group. In addition, a significant reduction in the levels of cardiac damage markers, as well as a reduction in the extent of cardiac damage, was found. In conclusion, PoPEx pre-treatment significantly attenuated the isoprenaline-induced myocardial damage, primarily via the preservation of endogenous antioxidant capacity in the rat model of takotsubo-like cardiomyopathy.

Introduction: Musculoskeletal disorders (MSDs) are common in men and women of all ages in all sociodemographic strata of society. Pain and functional limitations caused by MSDs severely limit independence and quality of life and interfere with an individual’s ability to participate in family and social life and work. The aim of this study is to investigate the effects of the Kinesio Tape (KT) technique on pain intensity in patients with MSDs of the upper and/or lower extremities before, during, and after therapeutic treatment. Methods: The study involved 123 patients of both sexes and all ages diagnosed with MSDs of the upper and/or lower extremities. Patients were randomly divided into two groups, a control group and an experimental group. The control group received the standard therapy protocol for MSDs, while the experimental group received the standard therapy protocol for MSDs plus the KT technique on the treated segment. The brief pain inventory was used to assess pain intensity. Both groups of participants were tested with the research instruments at baseline, during and after therapeutic treatment. Results: The ability to walk due to pain was significantly less impaired in the control group than in participants in the experimental group, in whom pain significantly impeded walking (p < 0.001). Normal walking was significantly more impaired in the experimental group than in the control group (p = 0.001). Pain significantly impaired relationships with others in the experimental group compared to the control group (p < 0.001). Conclusion: Subjects in the experimental group showed a significant decrease in pain in all areas after therapeutic treatment with KT compared to subjects in the control group.