As part of many national energy transition strategies, solar photovoltaic (PV) capacity is expected to increase significantly because PV deployment represents a key pathway for decarbonizing the energy sector. Alongside utility-scale installations, distributed PV systems connected to near-end users are becoming increasingly common in distribution networks. However, integrating intermittent sources without demand-matching capabilities introduces challenges related to operational network constraints. Consequently, distribution system operators (DSOs) limit PV integration to an acceptable level, referred to as hosting capacity (HC). Moreover, with increasing PV penetration, the curtailment of production becomes necessary during certain periods. Although curtailment has traditionally been avoided owing to the associated loss of clean energy, techno-economic studies show that shifting toward curtailment management can increase both HC and profitability. Curtailment management can be achieved through flexible PV power control, energy-storage integration, demand-side management, and flexible network regulation devices. This study specifically focuses on the techno-economic performance of flexible PV power control and compares it with the conventional approach without curtailment management, energy storage-based solutions, and their combination. The analysis was conducted on a modified IEEE 33-node test network, and key network constraints were incorporated. Using sequential Monte Carlo simulations with correlated stochastic time-series data for PV production, load profiles, and electricity prices over the years, the optimal PV and/or energy storage capacities were determined for various configurations. The results demonstrate that flexible curtailment management can increase both PV HC and expected profit, providing DSOs with boundary HC values while offering investors insight into the profitability of further PV integration.
Introduction: Regular physical activity reduces the risk of cardiovascular diseases (CVD). The aim of this study was to examine the association of physical activity with the severity of carotid disease. Materials and methods: This cross-sectional study involved 506 patients from the Vascular Surgery Clinic at the Institute for Cardiovascular Diseases "Dedinje", who underwent carotid endarterectomy from 2012 - 2017 . The severity of carotid disease was assessed based on the degree of carotid stenosis, plaque type, and patients' symptomatic status before surgery. Patient physical activity data were collected using the standardized Baecke questionnaire. Univariate and multivariate logistic regressions were performed to examine the association between physical activity and the severity of carotid disease. Results: According to univariate analysis, there was no statistically significant association between any form of physical activity (occupational, sports, or recreational) and the degree of carotid stenosis, nor with other characteristics. Also, physical activity was not associated with complicated carotid plaque. The only characteristic associated with complicated carotid plaque was the use of oral anticoagulants in therapy (OR=2.91; 95% CI=1.12-7.52; p=0.028). The relationship between physical activity and symptomatic carotid disease was not observed, but according to multivariate analysis, the following factors were associated with symptomatic status: age (OR=0.97; 95% CI 0.94-0.99; p=0.016), gender (OR=0.64; 95% CI 0.44-0.99; p=0.028), family history of CVD (OR=0.63; 95%CI 0.43-0.94; p=0.022), use of clopidogrel (OR 1.79; 95% CI 1.18-2.71; p=0.006) and ACEIs in therapy (OR=1.60; 95% CI 1.02-2.53; p=0.041). Conclusion: Physical activity was not associated with carotid disease severity.
Introduction/Objective. Urinary tract infections (UTIs) in children represent a significant public health problem due to their high prevalence and the need for timely diagnosis and adequate treatment. Automated methods using fluorescent flow cytometry are increasingly being used in laboratories for the screening of UTIs. The aim of this study was to determine the cut-off values for leukocyturia and bacteriuria using fluorescent flow cytometry for the screening of urinary tract infections in the pediatric population. Methods. A total of 821 urine samples were cultured, of which 366 samples met the criteria for fluorescent flow cytometry on the automated Sysmex UF-4,000 analyzer. The number of leukocytes and bacteria was compared with the culture results. Results. Of the total urine cultures tested, 209 (25.5%) were positive, and 599 (73%) were negative. There was a statistically significant difference in the prevalence of uropathogens according to the age of the children (p < 0.001). The area under the curve (AUC) for leukocyte count was 0.77 (95% CI: 0.71-0.84), while the AUC for bacterial count was 0.85 (95% CI: 0.81-0.89). A low negative likelihood ratio (0) was observed at the cut-off for bacteria of 40.1, and the negative predictive value was high (between 91% and 99%). Conclusion. Determination of leukocyte and bacterial counts in urine in children using fluorescent flow cytometry can serve as an initial test when deciding on urine culture in microbiological laboratories. These results may indicate the necessity of reducing unnecessary urine cultures while providing faster confirmation of negative test results.
In this paper, the physical layer secrecy performance of the classical Wyner wiretap channel with gamma-shadowed two-wave with diffuse power (GS-TWDP) composite fading is investigated. A closed-form expression for the average secrecy capacity (ASC) is derived, assuming that the transmitter dynamically adapts its transmission rate based on the available channel state information (CSI) of both the legitimate receiver and the eavesdropper. The derived expression is validated through Monte Carlo simulations and used to conduct a detailed analysis of the impact of shadowing and multipath severity on ASC. To further enhance secrecy performance in GS-TWDP fading environments, an optimal power allocation strategy is also designed and integrated with rate adaptation. The resulting secrecy performance is compared to that achieved using only rate adaptation, providing insight into the effectiveness of the joint power/rate adaptation strategy under varying composite fading conditions.
Background: Clozapine is the most effective antipsychotic for treatment-resistant schizophrenia, and abrupt discontinuation can lead to severe neuropsychiatric destabilization, including withdrawal catatonia. High-potency dopamine D2 receptor antagonists may further precipitate neuroleptic malignant syndrome (NMS), a condition with substantial clinical overlap with malignant catatonia. Objective: This report follows CARE guidelines to provide a structured and transparent description of a complex case involving abrupt clozapine withdrawal and rapid antipsychotic transition. Case presentation: This report describes a male patient with schizophrenia who developed malignant catatonia with overlapping NMS features following abrupt clozapine withdrawal and initiation of fluphenazine. Conclusion: The case underscores the importance of cautious antipsychotic transitions and early recognition of catatonia and NMS.
Background/Aim: Selecting appropriately sized maxillary anterior teeth is of great importance for achieving satisfactory outcomes in complete denture therapy. When pre-extraction records are unavailable, clinicians use recommended anatomical landmarks for this purpose. Predictive value of these parameters in previous studies was inconsistent. The aim of this study was to assess sex-specific associations between selected hard palate measurements and the mesiodistal width of maxillary anterior teeth (ATW) in an adult Bosnian-Herzegovinian population. Materials and Methods: This retrospective cross-sectional study used 180 maxillary casts (114 women, 66 men). Recorded palatal dimensions included hamular distance, hard palate length, and distances from the incisive papilla to the right and left hamular notches. The mesiodistal width of the six maxillary anterior teeth was summed to obtain ATW. Sex differences were assessed using independent-samples and paired-samples t-tests. Associations between palatal measurements and ATW were evaluated using simple and multiple linear regression (α=0.05). Results: Men had higher mean values for almost all palatal and dental variables, with no significant difference observed for the left lateral incisor (p=0.155). ATW was significantly greater in men compared with women (t=3.96, p<0.001). Papilla-hamular notch distances (p=0.002) were significantly associated with ATW in men, while all palatal measurements showed significant simple correlations (p≤0.002) with ATW in women. In multiple regression, no palatal dimension remained independently predictive in men (R²=0.173, p=0.019), while hamular distance was the only significant predictor in women (β=0.219, p=0.020; R²=0.169, p<0.001). Conclusions: Hard palate measurements show sex-specific relationships with the width of maxillary anterior teeth. Although several dimensions have significant associations with ATW, their predictive value is modest. Therefore, these parameters may serve only as supportive guides when selecting artificial teeth.
Background: Chronic periodontitis is a biofilm-induced inflammatory disease leading to progressive destruction of periodontal supporting tissues. Mechanical debridement by scaling and root planing (SRP) remains the gold standard of therapy; however, complete elimination of pathogenic microorganisms from deep periodontal pockets is challenging. Adjunctive laser therapy has been proposed to enhance clinical outcomes. Objective: To compare the clinical effectiveness of two diode laser wavelengths (980 nm and 445 nm) as adjuncts to subgingival curettage/SRP in the treatment of periodontal pockets, and to evaluate their outcomes relative to SRP alone. Materials and Methods: Comparative analysis of two independent prospective studies with identical methodology were analyzed. The first study included 24 subjects (1,164 periodontal pockets) treated with SRP + 980 nm diode laser (SmilePro 980, Biolitec, Germany). The second study included a same number of subjects and a comparable number of periodontal pockets were treated (862 periodontal pockets) with SRP + 445 nm diode laser (SiroLaser Blue, Dentsply Sirona, Germany). Control groups received SRP alone. Clinical parameters included Plaque Index (PI), Gingival Index (GI), Bleeding on Probing (BOP), Probing Pocket Depth (PPD), and Clinical Attachment Level (CAL), assessed at baseline and 1 month post-therapy. Results: Both laser groups demonstrated statistically significant reductions in PI, GI, BOP, and PPD compared with baseline (p < 0.05). When compared to SRP alone, both adjunctive laser therapies showed significantly greater improvement in PPD reduction and CAL gain (p < 0.05). No statistically significant difference was observed between the 980 nm and 445 nm laser groups in overall clinical outcomes (p > 0.05). Conclusion: Both diode laser wavelengths (980 nm and 445 nm) significantly enhance short-term clinical outcomes when used adjunctively with SRP compared to SRP alone. No clear superiority of one wavelength over the other was demonstrated under the applied clinical conditions.
Objective: Ergonomics in dental practice plays a crucial role in maintaining professional health, as prolonged static postures and repetitive movements significantly increase the risk of work-related musculoskeletal disorders among dental professionals. Understanding ergonomic risk factors and their impact on musculoskeletal health is essential for identifying vulnerable groups and developing effective preventive strategies in dental practice. Aim: The aim of this study was to assess the occurrence of musculoskeletal pain as a manifestation of work-related musculoskeletal disorders among dentists and to analyze its association with demographic characteristics, work habits, and dental specialization. Materials and Methods: This cross-sectional study included 130 dentists from various dental specialties. Data were collected using a structured questionnaire addressing demographic variables, work habits, ergonomic conditions, and the presence of musculoskeletal pain. Descriptive statistical methods were applied, and chi-square tests were used to analyze associations between categorical variables, with statistical significance set at p < 0.05. Results: The results indicated that the majority of participants experienced work-related musculoskeletal disorders, with prevalence increasing with age and length of professional experience. Occupational factors such as prolonged sitting or standing, improper working posture, lack of ergonomic chairs, and insufficient physical activity were significantly associated with the occurrence of work-related musculoskeletal disorders (p < 0.05). A statistically significant association was also observed between dental specialty and the presence of work-related musculoskeletal disorders (χ²(9) = 25.83; p < 0.01). The highest prevalence was reported among specialists in prosthodontics, pediatric dentistry, orthodontics, and endodontics, while lower prevalence was observed among oral surgeons, general dental practitioners, and periodontists. Conclusion: These findings emphasize the importance of implementing ergonomic interventions, regular physical activity, and preventive strategies in dental practice to reduce the occupational risk of work-related musculoskeletal disorders.
Background: Artificial intelligence (AI) is applied in numerous areas of society and has also led to significant changes in the field of medicine. Medicine is a branch of science of exceptional importance, and it is therefore necessary to ensure a high level of patient protection. The quality of healthcare has significantly improved through the use of artificial intelligence in various stages of the medical process, from the analysis of medical data and diagnostics, through therapy planning, to patient monitoring and the management of healthcare systems. Objective: The aim of this paper is to analyze the civil law aspects of artificial intelligence in medicine, with a particular focus on questions of liability for damage resulting from the use of such systems. Methods: The paper will first present the basic characteristics and areas of application of artificial intelligence in medicine, and then examine potential sources of damage and the legal basis for the liability of various stakeholders, including AI system manufacturers, software developers and data providers, healthcare institutions, and healthcare professionals. Special attention will be given to the challenges of proving causation and allocating liability in situations where decisions are made or supported by autonomous algorithmic systems. Results and Discussion: However, at the same time, numerous legal issues arise, particularly in the field of civil liability in cases where the application of artificial intelligence results in harm to a patient. Given the great importance of medicine and the need to ensure a high level of patient protection, the application of artificial intelligence must be accompanied by appropriate legal protection. The paper gives answers to a number of questions, with particular emphasis on the question of who may be held liable for damage caused by the use of artificial intelligence in medicine, as well as under which regulations and in what manner such liability is determined. Conclusion: Artificial intelligence has the potential to significantly enhance medical practice, its application must be accompanied by appropriate legal mechanisms that ensure patient protection and clearly define the responsibility of all participants in the system. Future legal development in this area will likely focus on further adapting existing civil law institutions to the specificities of artificial intelligence, while simultaneously strengthening preventive risk management mechanisms and transparency of AI systems in medicine.
This year the journal “Medical Archives” celebrates 80th anniversary of the establishiment (1947-2026). With the name “Medicinski Arhiv” this journal was founded in the year 1947 as official journal of the Society of physicians of Bosnia and Herzegovina (B&H). The first Editorial board was consisted of professors of the Faculty of Medicine of the University in Sarajevo opened in November 16th 1947: Vladimir Čavka, Blagoje Kovačević, Bogdan Zimonjić and Ibro Brkić. “Medical Archives” journal was a key milestone that helped in education of all academic and professional staff that became the foundation of Bosnian and Herzegovinian medicine, as a science and health care as a profession. The oldest medical journal in BiH was “Jahrbuch des Bosnisch-Herzegowinischen Landesspitales in Sarajevo” (“Annual of the National Hospital in Sarajevo”) which was established in 1897 and printed in German language in the period from 1897 until 1900. From the year 1950 “Medicinski Arhiv” was included in the most influential and important index database MEDLINE, as one of oldest medical journals in Souut-Eastern Europe. The first aim of journal was to give a opportunity to young researchers from BiH to present their scientific and research work to wider community. The tradition of publishing of “Medical Archives” as the most recognizable journal in BiH, was kept by Editor of Professor Izet Masic in 1993 who in extraordinary and difficult occasions (during wartime in BiH from 1992 until 1995) re-established journal and continued printing of the war issues. Hopefully the MEDLINE did not stop to continue receiving “Medicinski arhiv” journal and did not stop accept of published articles of “Medicinski Arhiv” in Medline/PubMed, SCOPUS, EMBASE, HINARI, EBSCO, and a lot of other indexed databases. From the year 2013 articles published in “Medical Archives” was included in PubMed Central with full papers (in extenso). Today “Medical Archives” belong to the most cited journals in former Yugoslavia countries with h-Index 38 in SCImago rank, it means 38 published papers in “Medical Archives” were cited 38 times in other indexed scientific journals worldwide, with SJR 0.33 and Q3 in the year 2024.
The aim of this study was to evaluate the strength of the left and right hamstring and the quadriceps muscle group in professional handball players. It also aimed to assess the statistical significance of the relationship between these two muscle groups. The study included eight professional handball players from the "Borac" team, Banja Luka. Standard anthropometric measurements were taken. The following variables were assessed: maximum quadriceps torque (MQT), maximum hamstring torque (MHT), and hamstring–quadriceps ratio (HQR), to determine the presence of muscle imbalances bilaterally and unilaterally. Isokinetic testing of knee strength was performed on both knees at the Institute for Sports, Faculty of Physical Education and Sports, University of Banja Luka, using the CON-TREX CYK device, which allows comprehensive assessment of muscle and joint function. Based on the findings, there was no significant muscle imbalance in handball players, i.e., no significant difference in quadriceps or hamstring strength between the left and right legs, either bilaterally or unilaterally (p > 0.05). The strength of the left and right quadriceps and hamstrings showed minimal variation, with no evidence of muscle imbalance. In professional and elite sports, information from isokinetic diagnostics is essential for designing training programs and preventing injuries. This study provides normative data for the handball player population.
<p>The demand for stainless steels has been steadily increasing across industries such as automotive,<br />aerospace, aviation, medical technology, and household appliances, primarily due to their excellent<br />corrosion resistance, low thermal conductivity, and favorable strength-to-weight ratio. Many of<br />these applications involve components with complex geometries and strict dimensional<br />tolerances, making machinability a crucial factor.<br />Technical surfaces are not ideally smooth geometric surfaces separating two media, but are, from<br />a microscopic point of view, rough surfaces characterized by a series of irregularities of different<br />sizes, shapes, and arrangements. The roughness represents the microgeometric irregularities of the<br />surface, i.e., unevenness at the small reference length (l) of a given direction of the surface.<br />According to the available literature, the effect of alloying elements on roughness during<br />conventional turning has not been sufficiently investigated. Therefore, the objective of this study<br />is to investigate and quantify the effect of alloying elements and nonmetallic inclusions on<br />roughness magnitudes in the longitudinal turning process of X8CrNiS18-9 stainless steel.</p>
Smoking is a serious public health problem, as smoking and passive exposure to tobacco smoke are important risk factors for global morbidity and mortality. It also negatively affects the structure and functionality of the sensory-motor-oral system, disrupting key functions such as breathing, phonation, chewing and swallowing. Therefore, the aim of this research is to investigate the influence of cigarette consumption on olfactory function and compensatory muscle movements during the oral phase of swallowing. 80 respondents participated in the research (40 smokers and 40 respondents who did not consume tobacco products). The research procedure included examination and analysis of the subject's olfactory ability in the form of recognition of presented smells. The compensatory movements of the lip muscles - musculus mentalis and musculus orbicularis oris - were evaluated. The research results showed that smokers have a weak ability of olfactory perception compared to non-smokers, which implies the occurrence of muscle compensation during swallowing.
<p style="text-align: justify; text-justify: inter-ideograph;"><span dir="auto" style="vertical-align: inherit;"><span dir="auto" style="vertical-align: inherit;">Proučavana je fauna ptica duž masiva planine Orjen i graničnog područja parka uz rijeku Trebišnjicu. Analiza je obuhvatila staništa i migracije u periodu od ljeta 2021. do jeseni 2023. godine, s ciljem dugoročnog praćenja, prognoziranja i zaštite vrsta. </span></span><br /><span dir="auto" style="vertical-align: inherit;"><span dir="auto" style="vertical-align: inherit;">Metode korištene za praćenje, označavanje, snimanje i obradu podataka uključivale su: metodu kilometarskog transekta, tačkasti popis, kretanje po slobodno odabranim rutama i metodu "reprodukcije". Analizirana su i prethodna istraživanja faune ptica u ovom parku kako bi se sintetizirali rezultati. </span></span><br /><span dir="auto" style="vertical-align: inherit;"><span dir="auto" style="vertical-align: inherit;">Glavni rezultati dobijeni nakon terenskog istraživanja su sljedeći: sastavljen je sistematski popis vrsta ptica, potkrijepljen foto albumom, a kreirane su i karte koje prikazuju najvažnija staništa za gniježđenje.</span></span></p> <p style="text-align: justify; text-justify: inter-ideograph;"><span dir="auto" style="vertical-align: inherit;"><span dir="auto" style="vertical-align: inherit;">Prijedlog je predstavljen upravi parka prirode i zainteresovanim stranama za ovo područje, s ciljem zaštite vrsta i osiguranja njihove održivosti unutar staništa.</span></span></p>
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