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ABSTRACT Scholarship on diaspora political engagement is unfolding in novel ways exploring the participation of second-generation diaspora individuals and engagement patters of authoritarian and hybrid regimes. Focusing on the unique role of diaspora politicians, I contend that these individuals adeptly leverage their identity to impact politics and advocate for change. The article demonstrates their adaptability in different settings and evolving advocacy strategies. The article employs a multilingual analysis of social media, public interviews, and public appearances in Germany and Bosnia and Herzegovina using an exploratory case study of a German-Bosnian politician. This exploration underscores their flexibility and evolving advocacy dynamics. Furthermore, it illustrates the way these politicians enhance their profiles within the countries where they’ve been elected and in countries of their descent. This serves to strengthen their chances of re-election on one hand while also drawing attention to authoritarian tendencies, potentially clearing a path for democratic advancement on the other.

S. Bermudo, Iztok Peterin, Jelena Sedlar, R. Škrekovski

The modular product $G\diamond H$ of graphs $G$ and $H$ is a graph on vertex set $V(G)\times V(H)$. Two vertices $(g,h)$ and $(g^{\prime},h^{\prime})$ of $G\diamond H$ are adjacent if $g=g^{\prime}$ and $hh^{\prime}\in E(H)$, or $gg^{\prime}\in E(G)$ and $h=h^{\prime}$, or $gg^{\prime}\in E(G)$ and $hh^{\prime}\in E(H)$, or (for $g\neq g^{\prime}$ and $h\neq h^{\prime}$) $gg^{\prime}\notin E(G)$ and $hh^{\prime}\notin E(H)$. A set $D\subseteq V(G)$ is a dominating set of $G$ if every vertex outside of $D$ contains a neighbor in $D$. A set $D\subseteq V(G)$ is a total dominating set of $G$ if every vertex of $G$ contains a neighbor in $D$. The domination number $\gamma(G)$ (resp. total domination number $\gamma_{t}(G)$) of $G$ is the minimum cardinality of a dominating set (resp. total dominating set) of $G$. In this work we give several upper and lower bounds for $\gamma(G\diamond H)$ in terms of $\gamma(G),$ $\gamma(H)$, $\gamma_{t}(\overline{G})$ and $\gamma _{t}(\overline{H})$, where $\overline{G}$ is the complement graph of $G$. Further, we fully describe graphs where $\gamma(G\diamond H)=k$ for $k\in\{1,2,3\}$. Several conditions on $G$ and $H$ under which $\gamma (G\diamond H)$ is at most $4$ and $5$ are also given. A new type of simultaneous domination $\bar{\gamma}(G)$, defined as the smallest number of vertices that dominates $G$ and totally dominates the complement of $G,$ emerged as useful and we believe it could be of independent interest. We conclude the paper by proposing few directions for possible further research.

M. Meland, O. Frøynes, M. Fotirić Akšić, N. Pojskić, B. Kalamujić Stroil, Merima Miralem, A. Konjić, F. Gaši

In order to ensure the long-term sustainability of the conservation process of Norwegian plum germplasm, as well as to enhance the possibility of its utilization, a central plum heritage cultivar collection was established in 2020. In this study, 40 plum accessions maintained at the Ullensvang plum heritage cultivar collection were genetically characterized using a set of nine microsatellite markers recently approved by the ECPGR Prunus working group. The obtained molecular data were used to investigate the genetic identity, diversity, and structure among the analyzed accessions. No redundancies were detected among the plum accessions, which is in stark contrast to the previous molecular study on plum samples collected through an on-farm inventory of Southern Norway. Furthermore, the obtained data indicate that the Ullensvang collection contains a significant genetic diversity of Norwegian plum germplasm, previously held in decentralized sites. With that in mind, this collection can certainly be considered for the role of the National Clonal Plum Germplasm Repository. The nine microsatellite markers, recommended by ECPGR, revealed a genetic structure not entirely tied to previously proposed pomological groups, possibly indicating a history of hybridization among members of the various groups.

Joshua P. Kulasingham, H. Innes-Brown, Martin Enqvist, E. Alickovic

The auditory brainstem response (ABR) is a measure of subcortical activity in response to auditory stimuli. The wave V peak of the ABR depends on stimulus intensity level, and has been widely used for clinical hearing assessment. Conventional methods to estimate the ABR average electroencephalography (EEG) responses to short unnatural stimuli such as clicks. Recent work has moved towards more ecologically relevant continuous speech stimuli using linear deconvolution models called Temporal Response Functions (TRFs). Investigating whether the TRF waveform changes with stimulus intensity is a crucial step towards the use of natural speech stimuli for hearing assessments involving subcortical responses. Here, we develop methods to estimate level-dependent subcortical TRFs using EEG data collected from 21 participants listening to continuous speech presented at 4 different intensity levels. We find that level-dependent changes can be detected in the wave V peak of the subcortical TRF for almost all participants, and are consistent with level-dependent changes in click-ABR wave V. We also investigate the most suitable peripheral auditory model to generate predictors for level-dependent subcortical TRFs and find that simple gammatone filterbanks perform the best. Additionally, around 6 minutes of data may be sufficient for detecting level-dependent effects and wave V peaks above the noise floor for speech segments with higher intensity. Finally, we show a proof-of-concept that level dependent subcortical TRFs can be detected even for the inherent intensity fluctuations in natural continuous speech. Visual abstract Significance statement Subcortical EEG responses to sound depend on the stimulus intensity level and provide a window into the early human auditory pathway. However, current methods detect responses using unnatural transient stimuli such as clicks or chirps. We develop methods for detecting level-dependent responses to continuous speech stimuli, which is more ecologically relevant and may provide several advantages over transient stimuli. Critically, we find consistent patterns of level dependent subcortical responses to continuous speech at an individual level, that are directly comparable to those seen for conventional responses to click stimuli. Our work lays the foundation for the use of subcortical responses to natural speech stimuli in future applications such as clinical hearing assessment and hearing assistive technology.

Matko Rošin, Nela Kelam, Ivana Jurić, Anita Racetin, Marin Ogorevc, Brieuc Corre, Davor Čarić, N. Filipović et al.

The gradual deterioration of articular cartilage was thought to be the central event in osteoarthritis (OA), but recent studies demonstrated the importance of low-grade synovitis in the progression of OA. The Syndecan (SDC) family of membrane proteoglycans is known to be involved in the regulation of inflammation, but there is limited evidence considering the role of syndecans in OA synovitis. Our study aimed to investigate the hip OA synovial membrane expression patterns of SDC1, SDC2 and SDC4, as well as exostosins and sulfotransferases (enzymes involved in the polymerisation and modification of syndecans’ heparan sulphate chains). Synovial membrane samples of patients with OA (24) were divided into two groups according to their Krenn synovitis score severity. The immunohistochemical expressions of SDC1, SDC2, SDC4, EXT1, EXT2, NDST1 and NDST2 in synovial intima and subintima were then analysed and compared with the control group (patients with femoral neck fracture). According to our study, the immunoexpression of SDC1, NDST1 and EXT2 is significantly increased in the intimal cells of OA synovial membrane in patients with lower histological synovitis scores and SDC4 in patients with higher synovitis scores, in comparison with non-OA controls. The difference in the expression of SDC2 among the OA and non-OA groups was insignificant. SDC1, SDC4, NDST1 and EXT2 seem to be involved as inflammation moderators in low-grade OA synovitis and, therefore, should be further investigated as potential markers of disease progression and therapeutic goals.

I. Šestan, Sabina Begić, Melisa Ahmetović, H. Keran, Erna Begić, Dženana Mehmedović, Vanja Srebro

In accordance with consumer requirements, the water must be adequately purified, and the corresponding parameters within the defined values. Various methods are used for this purpose, of which the ion exchange method can be highlighted as the simplest, most efficient and economically profitable. Ion exchange is a reversible process of ion exchange between a solid phase and an electrolyte solution. The ion exchanger is a macromolecular insoluble material that has chemically bound electrified groups and mobile, oppositely charged ions that compensate for this electrification. Ion exchangers are usually used in the form of compact or granular beds that fill the column through which the solution with the ions to be exchanged flows.They usually contain phenolic, carboxylic, sulfonic amino and other groups, which is why the treatment also results in decarbonization, softening, demineralization and denitrification of water. As the assessment of water quality is based on the most significant physico-chemical parameters, the aim of the work is the analysis of drinking water before and after treatment with an ion exchanger.For this purpose, organoleptic parameters such as smell, taste and color were first analyzed. After that, physico-chemical parameters were analyzed: pH values, electrical conductivity, m-alkalinity, p-alkalinity, water hardness, organic matter content, chloride content, iron and manganese content. An ion exchanger based on resin was used, which after use was regenerated by washing with NaClsolution.The analysis of the water sample, before and after the ion exchange treatment, showed that the treatment process was effective and that the decarbonization and softening of the water was carried out, whereby the water was categorized as soft water (water <9⁰dH).The analyzed water is tasteless, odorless and colorless before and after treatment. The results of the analysis showed that all the values of the analyzedphysico-chemical parametersare in accordance with the Rulebook on the Healthiness of Drinking Water(Official Gazetteof Federation of Bosnia and Herzegovina No.40/10) arebelow the maximum allowed values. KEYWORDS:water, ion exchange, physical-chemical parameters; water treatment

Maja Barbaric, Katarina Vukojević, Anita Kolobarić, Martina Orlović Vlaho, Tanja Krešić, V. Šoljić

Background: this study aimed to determine the expression of RNA-binding oncofetal proteins IMP3 and LIN28A in extravillous (EVT) and villous trophoblast (VT) cells of placentas from pre-eclamptic (PE) pregnancies to better understand the pathogenesis of PE. Methods: placental tissue of 10 patients with PE with severe features, 10 patients with PE without severe features and 20 age-matched healthy pregnancy controls were analyzed by immunohistochemistry, double immunofluorescence and qPCR. Results: We found a decreased percentage of IMP3-positive EVT cells in PE with and without severe features compared to that of the healthy control (p < 0.001). IMP3 expression was significantly low in VT of PE placentas compared to that of the healthy control (p = 0.002). There was no significant difference in LIN28A expression between groups of PE and the control group. Additionally, we noticed the trend toward downregulation of IMP3 mRNA and LIN28A mRNA in severe PE compared to that of healthy controls. Conclusions: We demonstrated that IMP3 expression is decreased in EVT and VT cells of placentas from pregnancies complicated with both PE with and without severe features. However, additional functional investigations are needed to clarify the role of IMP3 as a potential therapeutic target in the management of PE.

B. Malinović, Neda Brestovac, Dario Marjanovic, Dajana Dragić, Draženko Bjelić, T. Djuričić

The subject of this research wasto verify the feasibility of implementing green chemistry principles within the business company „Omorika Reciklaža“ Ltd. situated in Johovac near Doboj, Bosnia and Herzegovina. The objective of this study wasto conduct a detailed assessment of the company's facilities and operations, using environmental audits, to identify technological processes (production lines), energy and waste flows, capacities, product range, and other pertinent factors crucial for theapplication of green chemistry principles. Special emphasis was placed on analyzing each substance that constitutes a raw material, whether used individually or as part of mixtures.The assessment of safety data sheets involvedutilizing the CAS registration numbers of substances from the Chemical Abstracts Service, cross-referenced with the ECHA database (European Chemicals Agency). The outcomes, attained through an exhaustive analysis of each substance, were presented as a "chemical inspection" of the company. Through the analysis of all substances and mixtures in the technological process (chemical inspection), as well as the capacity of production flows, energy and resource flows, wastewater, and waste, the potential for enhancing the technological process wasidentified. This involvedreducing dust levels in the workspace, decreasing electricity consumption (utilizing renewable sources), and substituting particularly hazardous chemicals used in the technological process. KEYWORDS:green chemistry; chemical safety; SVHC;environmentalaudit

Nadina Kurtanović, Ena Gogić, E. Tanović, Damir Čelik, Elmina Mulić Hadžiavdić

There is increasing evidence of neurological involvement in patients with coronavirus disease. Reports of neurological manifestations include altered mental status, Guillain-Barré syndrome (GBS) and its forms, encephalopathy, psychosis, neurocognitive (dementia) syndrome, ischemic strokes, intracerebral hemorrhage, and acute transverse myelitis. We present three patients with rare neurological manifestations of the COVID-19 disease, with a special focus on rehabilitation in a health resort setting. Outcomes were evaluated based on neurological examination and the modified Barthel index. We highlight the importance of an interdisciplinary approach to reduce disability and improve functionality and quality of life.

Belma Alihodžić, Tatjana Atanasova-Pachemska, Sanela Nesimović

Teaching is a process for which its plan should contain reflection onto previous experience. With that in mind, teaching situations should be continuously researched and improved in accordance with the research results. Led by this thought and the fact that students are uncritically using visualization to solve mathematical problems, we defined the aim of this research–determine the attitude of students about the visualization of mathematical content (VMC). The subject of this research are the attitudes of students towards VMC. By analyzing our research subject, we have discovered the research problem–students use visual aid to solve problems uncritically. Based on this problem, we have set the aim of our research. Our aim was to determine the students’ attitudes (and their opinions) about VMC. Based on the aim of our research, we have set four research tasks. Based on these research tasks, we have established the main (leading) research question–What is the attitude of high school students towards the application of VMC? We divided the main research question into five questions: Do high school students consider that they understand the term ‘VMC’? Who considers they use more methods of solving mathematical problems using visual aid–high school male students or female students? Students of which grades consider that they use solving problems using visual aid more? What is the attitude of high school students about the relationship between the substantiality of the picture (the amount of data it encompasses) and the difficulty of solving the problem? What is the attitude of students about the use of software to solve mathematical problems? The research has been conducted with 1,240 high school students from Sarajevo, Bosnia & Herzegovina. For the purposes of this article, we employed a survey, questionnaire-based research. The research was created as part of a larger study conducted in the context of preparing a doctoral dissertation related to VMC. It is one fundamental research. An essential aspect of this research involves students’ attitudes toward VMC. After obtaining all necessary approvals from relevant institutions and parents, students proceeded to testing and surveying in their school classrooms, under the supervision of designated individuals who facilitated the conduct of the research. The distribution of the data was not normal, so we used the Pearson Chi-square, likelihood ratio Chi-square, and linear-by-linear association test to examine the association between student attitudes and categorical variables (gender and grade). In addition, we used frequencies and percentages. It has been concluded that the students are mostly positive towards applying visualization in their process of solving mathematical problems and these should be used in the direction of improving the students’ success, their confidence and their level of contentment in their mathematics class, as well as in other life situations that encompass mathematical content. In future research, it could be examined why students expressed such attitudes about the presented situations. Additionally, it would be significant to explore why students do not consider themselves successful in applying VMC, despite claiming to understand the term. The analysis could extend to the content presented in textbooks or instructional materials students use–how visualized the content is or whether students are required to visualize it themselves. It would also be worthwhile to investigate the extent to which teachers encourage students to visualize specific tasks or do so on their behalf. Given the fluctuation in results (we observe affirmative answers–partially or completely) observed across grades–initial decrease, subsequent increase, followed by another decrease–it might be explored whether this is related to the curriculum taught in each grade (such as content, volume, number of class hours, etc.). Regarding images leading to incorrect conclusions, it would be interesting to investigate the types of images students have in mind, how frequently they encounter such situations, where they use these images, who creates them, and similar aspects. These are just some questions for future research.

Mirha Pjanic, M. Aleckovic-Halilovic, N. Bašić-Jukić

The John Cunningham virus (JCV) is a polyomavirus that usually infects people at a young age and does not cause any symptoms in immunocompetent individuals. However, in immunocompromised individuals, such as kidney transplant recipients, JCV can cause severe and potentially fatal disease. Unfortunately, JCV has not been researched as extensively as the BK virus and is not mentioned in relevant kidney transplant guidelines. This lack of attention to JCV can lead to less consideration in kidney transplant patients’ care. Surveillance using locally available diagnostic methods is of the utmost importance. The presence of JCV can be diagnosed with urine decoy cells, viruria, or viremia verified by the PCR method. A low threshold for considering JCV as a possible cause of any neurological or renal dysfunction in kidney transplant recipients must be maintained. In such cases, kidney and brain biopsy are indicated. Maintaining the appropriate immunosuppression while avoiding over-immunosuppression to prevent JCV disease is crucial, and the approach should be individual, according to overall immunological risk. We hypothesize that the presence of the JCV can indicate overt immunosuppression and identify kidney transplant recipients more prone to opportunistic infections and diseases, including some malignancies. To explore that, future observational studies are needed.

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