Acne vulgaris (acne) is chronic inflammatory dermatosis which affects the pilosebaceous unit, with a varied clinical picture including inflammatory and non-inflammatory cutaneous lessions. This multifactorial disease mostly occurs in adolescents; however, it can also affect children and adults. Different therapy options for acne treatment exist, comprising topical, systemic and hormonal agents or a combination thereof. The choice of the therapy depends on various factors, for instance the severity and extent of the disease and site of involvement. Commonly used topical acne therapies include benzoyl peroxide, salicylic acid, antibiotics, retinoids, azelaic acid, sulfone agents and their combinations. Systemic antibiotics are indicated for use in moderate to severe inflammatory acne and should be used in combination with a topical retinoid and benzoyl peroxide. The available conventional formulations often cause side effects such as skin irritation, dryness, peeling, itching, leading to reduced patient compliance and compromised therapeutical efficacy. Novel drug delivery systems are promising option for improved acne treatment outcome, as they can diminish the side effects caused by the therapeutic agents or can modulate their properties and at the same time offering possibilities for modified release and improved skin penetration of the active substances. The cosmetics manufacturers implement micro/nanotechnology in their formulations, while patent protection for cosmetics has gained more importance over the past decades. This review focuses on micro/nanoparticulated carrier systems that can be used for acne treatment and the published patents concerning them.

Lichen is a symbiotic plant built by the cells of algae and fungi hyphae. Algae are usually presented - green (Chlorophyta) or blue green (Cyanophyta), a mushroom commonly found is ascomycetae and sometimes basidiomycetae. Mushrooms receive oxygen and carbohydrates from algae, and they in turn provide water, CO2 and mineral salts. Lichens are often found on trees and rocks in unpolluted environments and can be used as a bioindicator species. In during 2015-2016. was realized a survey of epiphytic lichen flora of the western mountains in environment of Vranje. Sampling was carried out at 4 locations: Borino brdo, Krstilovica, Markovo Kale and Pljackovica. Based on the collected and determined samples can be concluded that the study implemented of the area of 25 species of lichens of which: 8 as crust, leafy 12 and 5 shrub. The research results indicate that the lichen flora of the western mountains environments Vranje of a rich and diverse as a result of favorable geographic position, geological and soil composition, climate and plant cover that provide opportunities for the development and survival of lichens.

Noise is any unwanted sound. This means that every sound effects (buzzing, noise, magnifier, speech and so on.), which interferes with work or rest, is noise. Communal noise generated by all noise sources that are found in the human environment, excluding the noise that occurs at the workplace in the industrial plants. It mainly comes from traffic and it's called traffic noise. Department of Public Health Vranje is authorized and accredited professional organization that performs measurements of noise pollution in the city of Vranje. Measurement of noise in both cycles included ten measuring points that are found in a residential area. The level of acoustical load at each measurement point is followed by three measurements in the daily interval and two measurements in a night interval. Made the daytime, evening and nighttime measurements at 53 measuring points (a total of 159 measurements) over a period of 15 minutes of noise. From the 53 measuring points are higher noise level at measuring point 51 (almost all measuring points) and ranges from 2 to 47.2 dB (tab. 1 Measuring points of noise pollution Vranje-2015-day / evening / night ). The way to combat environmental noise largely depends on the degree of development, economy, culture and politics. There is no estimate on the world level about the impact of noise on the environment and human health as well as estimates of the price of that impact. The existence of a modern harmonized with European regulations normative acts will be aimed at the maximum limit and control the exposure of the population of acoustic pollution.

The position of women in our society today is such that they constantly have to prove that they are capable of achieving the set targets and goals in their careers. In the world, as well as in Serbia, a lot has been done in this area and women still continue to work on gender equality and aim at constantly improving their position in all segments of society. Women who strive to achieve leadership positions in their careers have to continuously work on their professional development and show initiative to solve everyday tasks set before them. In Serbia, the trend of placing women in managerial positions is increasing rapidly each year, which leads to increased significance of the role of women in business decision making and society at large. The goal of conducted research in the City Administration of Belgrade was to prove the existence of gender equality and the equal status of women, as well as to show that there are opportunities which they can use to advance in their careers and become equal with men.