Breast cancer is a serious health problem. It is the most common cancer in women. The aim of this study was to estimate the concordance between ER, PR receptor and HER-2 immunohistochemistry assessment scores in pared CNB (core needle biopsy) and surgical specimens. Histological grade, oestrogen receptor (ER) status, progesterone receptor (PR) status, and human epidermal growth factor receptor-2 (HER2) status were evaluated in a blinded fashion in CNB and in surgical excision specimens. Absolute concordance rate between core needle biopsies and surgical specimens for histological grade was 50% with κ value (0,15) for ER 92% with κ value (0,79), PR 88% with κ value (0,73) and for HER2 96% with κ value (0,91). CNB can provide reliable information in evaluation of ER, PR and HER2 status in an invasive breast carcinoma. Ključne reči: breast cancer, core needle biopsy, oestrogen receptors, progesterone receptors, HER-2. Analiza odstupanja statusa hormonskih receptora i receptora za epidermalni faktor rasta 2 u uzorcima dobijenim iglenom biopsijom i hirurškim uzorkom kod obolelih od invazivnog karcinoma dojke Ljiljana Tadic Latinovic1, Zivka Eri2, Darko Jovic3, Aleksandra Salapura1, Jovan Culum3, Branislava Jakovljevic3, Ilija Baros1, Slavica Maric4 1 Department of Pathology, University Clinical Center of Republic of Srpska, Banja Luka, Republic of Srpska, Bosnia and Herzegovina 2 Canter for Molecular Genetics, Institute for Pulmonary Diseases, Sremska Kamenica, Republic of Serbia 3 Surgical Clinic “S-Tetik”, Banja Luka, Republic of Srpska, Bosnia and Herzegovina 4 International Medical CantersCentar za Radioterapiju Banja Luka, Banja Luka, Republic of Srpska, Bosnia and Herzegovina

Paper compares numbers of publications published in indexed journals by authors from two cities, Tuzla and Sombor, approximately the same size during half of XX century, in order to determine how a newly opened medical school influences scientific research. Today, in Sombor only Faculty of Pedagogy exists (a part of Novi Sad University). From 1977-1979. number of publications from both cities was very low (only 2-4). Thirty years later, from 2009-2014. number of papers from Tuzla increased many fold (65-98 papers/year), while from Sombor remained low (0-4 papers/year) over the same period. Factors contributing to this phenomenon include: university environment, participation of most medical doctors in postgraduate research programs, exchange programs with other medical schools, both local and abroad, and significant financial support for medical students and research grants. Sombor enjoys no such financial support, and various temporary stimuli have failed to influence research and publishing significantly. Sombor doctors continue to present their observations and data at various meetings, but do not submit manuscripts to medical journals. Furthermore, the Sombor hospital administration does not support participation of physicians in graduate programs or doctoral studies. The rising number of published papers in Tuzla indicates that a larger medical center or hospital may not only inspire original research but may also guide busy physicians through process of publishing their manuscripts in medical journals. In this paper, details of postgraduate education at Medical School Tuzla are elaborated, and the idea of opening medical school in Sombor, first mentioned in the 1960s, is reiterated.

In this paper, the electrochemical properties of high - purity aluminium with the addition of small amounts of gallium at high cathodic potentials have been investigated. The anodic current was followed through time in order to determine the quantity of charge needed for the formed substances oxidation. Anodic current responses for the period of 1 s were recorded. Time responses for the cathodic and anodic currents were recorded and showed in characteristic diagrams. The range of low and high cathodic potentials (LCP, HCP) was defined for all samples. For the experimental work, standard electrochemical cell with saturated calomel electrode (SCE) and platinum counter electrode were used. The solution 2 M NaF was used for this work.

Conducting business by using the internet has become an everyday occurrence in all spheres of economy, as well as in the tourism sector. There is an increasing number of agencies in the world that conduct their business almost completely on-line. The aim of this research was to examine what characterizes the process of implementation of electronic business with tourist agencies in Serbia on the sample of 65 companies, and whether it differs depending on certain business characteristics. For that purpose, EBusTour model was developed that consists of 14 items grouped into four categories: online communication, online promotion, impact on sales and working hours reduction vs. sales improvement. As far as tourist agencies in Serbia are concerned, the results of the application of EBusTour model show that the most common activity in this field is basic online promotion (website implementation), followed by effects on sales. The paper also investigates whether there are differences in e-business implementation in relation to the characteristics such as: years in business, the type of licence (tour operator or sales agent) and the type of market (incoming, outgoing or combined).

The aim of this study was to determine the polycyclic aromatic hydrocarbons (Polycyclic aromatic hydrocarbon; PAH) with a focus on benzo (a) pyrene in smoked chicken produced in controlled conditions, changing the temperature values and time at constant pressure. The technological process of thermal degradation, drying and smoking semi-dry meat products of poultry meat is done in automated thermal chambers. The current process of smoking is performed by heat treatment to make the temperature at the center of the product 72° C for 40 minutes, followed by smoke at a temperature of 65° C, to achieve certain characteristics (odor, color). First category deboned chicken meat was used for testing. It was prepared in accordance to the familiar preparing raw material procedure for process of smoking already existing process of smoking is compliant with speci€c knowledge in science as well as principles of good manufacturing practice with a special focus on the time and temperature of smoke that led to certain changes in terms of the sensory properties of smoked products like presence and said polycyclic aromatic compounds (PAHs). The product was smoked at various temperatures ranging between 52.5 and 62 °C, over 10 to 30 minutes. In determining PAH compounds (polycyclic aromatic hydrocarbons), has been allocated said benzo (a) pyrene which is an indicator of the presence of harmful substances in products. Smoked meat changed the way smoking was ranked very acceptable