This paper describes the test platform for verifying the functionality of network protocols and for optimization of their parameters. The test bed is made using combined OPNET simulator and MATLAB development environment. This test platform connects OPNET network protocols simulator with MATLAB development environment in the way that OPNET runs simulations of network traffic, with the predetermined parameter values, while MATLAB executes the script with a mathematical algorithm, which optimizes parameters listed in OPNET simulator.

The scope, scale, and intensity of real, as well as potential, attacks on the Smart Grid have been increasing and thus gaining more attention. An important component of the Smart Grid cybersecurity efforts addresses the availability and access to the power and related information and communications infrastructures. In this paper, we provide a holistic and methodical presentation of taxonomies and solutions for DoS attacks in the Smart Grid. The emerging threats of cybertattacks are raising serious concerns for many critical infrastructures. In this regards, The scope, scale, and intensity of real as well as potential attacks on the Smart Grid are on the rise and with devastating consequences. An important component of Smart Grid cyberse-curity efforts addresses the availability and access to the power and related information and communications infrastructures. In this paper, a holistic and methodical presentation of taxonomies and solution for DoS attacks in the Smart Grid is presented.

Introduction: Cardiovascular complications in patients with subarachnoid hemorrhage are considered to be a neurally mediated process rather than a manifestation of coronary artery disease. Aim: The aim of study is to show the incidence and type cardiac complications after traumatic and spontaneous SAH. Patients and methods: The study had prospective character in which included 104 patients, with diagnosed subarachnoid hemorrhage (SAH), in the period from 2014 to 2017. Two groups of patients were formed. Group I: patients with SAH caused by the rupture of a brain aneurysm. Group II: patients with SAH after traumatic brain injury. Results: Electrocardiogram (ECG) abnormalities was predominant after traumatic brain injury 74 %, with statistically significant difference atrial fibrillation 42.5 % (p = 0.043) and sinus bradycardia 31.4 % (p = 0.05). Hypertension are predominant in patients with spontaneous SAH with statistically significant difference (15 (27.7%) vs 36 (72%) p=0.034) and hypotension in group II (10 (18.5%) vs 2 (4%) p = 0.021 ) with traumatic SAH patients. The time in Intensive Care Unit (ICU) for traumatic SAH group was 6.1 ± 5.2 days and 3.9 ± 1.16 for spontaneous SAH group with statistical significance (p = 0.046). Respiratory support time was longer in traumatic SAH group (39.4 ± 23.44 vs. 15.66 ± 22.78) with p = 0.043. Conclusion: Cardiac dysfunction in patients with subarachnoid hemorrhage are considered to be a neurally mediated process rather than a manifestation of coronary artery disease. Early treatment of cerebral injury could be reduce incidence of cardiac complications after traumatic brain injury. Cardiac dysfunction in patients with SAH is still very high, despite substantial qualitative progress in their treatment.

In this paper, we present our recent studies on pilot allocation and interference coordination for heterogeneous networks (HetNets) using massive multi-input-multi-output (mMIMO) technology in time division duplex (TDD) mode, where the macro-cell base station (MBS) and overlaid small-cell base stations (SBSs) share the same time-frequency resources, and thus co-tier and cross-tier interferences occur. We investigate how to coordinate such undesirable interference for maximizing the system sum-rate under required constraints. As the first approach, we present an uplink pilot allocation scheme to enhance the downlink system sum-rate by coordinating downlink cross-tier interference to small-cell users (SUs) based on the estimated uplink channel state information. In this approach, we study the optimum pilot allocation against the trade-off between two degradation factors, i.e., uplink pilot overhead and downlink cross-tier interference. As the second approach, we present a dynamic SBS clustering scheme to mitigate dominant co-tier interference among small cells (SCs), where the SBS clustering is carried out based on potential mutual co-tier interference strength between two SCs. We also consider the SBS precoder design in each cluster to further improve the downlink sum rate of SCs under SBS power constraint. Simulation results show that our proposals are useful approaches to enhance the sum rate performance in TDD-mMIMO-HetNets.

Introduction: Austro-Hungarian monarchy had great impact on healthcare system in Bosnia and Herzegovina (B&H), and consequences of that exist today. Aim: To launch of the section „The Most Influential Physicians in the Development of Health Care in Bosnia and Herzegovina“, in which, within next issues of the Medical Archives will be presented the prominent physicians, dentists and pharmacists who gave contribution to development of healthcare system in B&H. Results: This paper provides a full overview from the literature about health care circumstances during 150 years in Bosnia and Herzegovina and important of the role health care institutions and of all the doctors working in B&H during the Austro-Hungarian administration. To some of them is devoted more attention in the texts about their life and work and their contribution to the development of the health service in B&H. Also, author gave description of the others, except for the medical activities who have contributed to our homeland, such as Dr. Jozef Kecet, Dr. Julije Makanec, Dr. Teodora Krajewska, Dr. Josef von Preindlsberger, Dr. Hamdija Karamehmedovic and others, but there are many more that we should know about and mention them. Conclusion: The fact is Austro-Hungarian model of healthcare system in that time was functional for that period and great improvement in comparison to past and the fact is that that system represents a basis even for modern medicine in territory of B&H.

Carrier Frequency Offset (CFO) and (high) Peak-to-Average Power Ratio (PAPR) are well-known major drawbacks of the Orthogonal Frequency-Division Multiplexing (OFDM) signal. So, in many practical situations, specifically with LTE-Advanced downlink introducing carrier aggregation, estimation of PAPR and CFO-induced OFDM symbol phase deviation is of interest. However, this demands complex test equipment, such as e.g. Vector Signal Analyzer (VSA), which might not be always and everywhere available. Therefore, we applied the link abstraction principle on the residual BER that is considered to be determined just by the CFO-caused phase deviation, i.e. as if the channel is noiseless and time-dispersion-free (so that evident errors occur just due to actual CFO). Moreover, as recently it has been shown that the phase deviation is linear with the instantaneous (per-OFDM-symbol) PAPR, we develop a simple model for analytical estimating of BER-based CFO, considering the easy-to-measure BER degradation as resulting just from the according additive white Gaussian noise (AWGN) power level, which abstracts the CFO distortion. The proposed analytical model is validated by according Monte-Carlo simulations.

Introduction: Malignant breast cancer is the most common malignancy in women between 40 and 55 years of age. Dermatoglyphs are polygenetically determined properties, whose appearance and number are determined by a specific gene. They represent the skin reefs that are created by epidermis on the fingers or toes, palms and soles. Palmar dermatoglyphs have been used to estimate the hereditary basis of many diseases. Aim: The aim of the paper is to determine whether there is a statistically significant difference between the observed qualitative and quantitative parameters of both palms between the experimental and the control group. Material and Methods: A survey of the qualitative and quantitative properties of the palmar complex was carried out on a total of 100 female respondents. The first group included 50 women with breast cancer. Comparative data were used for the analysis of palmar dermatoglyphs in the second group of respondents, or 50 phenotypic healthy female subjects. The imprints of the palmar complex were taken using the printake ribbons, analyzed, and the data was then statistically processed and displayed in charts. An analysis of the number of reefs between two digital triradius was performed, followed by the determination of the axially triad position, as well as the ATD angle measurement. Results: Quantitative analysis of ATD-angle showed statistically significant difference between the left and right palms of the analyzed groups. However, the analysis of the number of reefs between triradius A-B, B-C, C-D did not show statistically significant results for both the left and right hand between the analyzed groups. Conclusion: These results indicate that the quantitative palmar parameter, ATD-angle, can play a role in identifying women with increased risk of breast cancer.

1Sarajevo School of Science and Technology, Sarajevo, Bosnia and Herzegovina 2University Clinical Center Sarajevo, Sarajevo, Bosnia and Herzegovina KeYWORdS: natriuretic peptides, brain natriuretic peptide, biomarker of myocardial infarction, Alzheimer’s disease. citAtiON: Cardiol Croat. 2018;13(11-12):435. | https://doi.org/10.15836/ccar2018.435 *AddReSS fOR cORReSpONdeNce: Edin Begic, Sarajevo School of Science and Technology, Sarajevo Medical School, Department of Pharmacology, Hrasnicka cesta 3a, 71000 Sarajevo, Bosnia and Herzegovina. / Phone: +38761303375 / E-mail: edinbegic90@gmail.com ORcid: Edin Begic, https://orcid.org/0000-0001-6842-262X • Suncica Hadzidedic, https://orcid.org/0000-0001-9026-8737 Ajla Kulaglic, https://orcid.org/0000-0003-3410-7079 • Belma Ramic-Brkic, https://orcid.org/0000-0002-8205-0137 Zijo Begic, https://orcid.org/0000-0002-1863-5755 • Mirsada Causevic, https://orcid.org/0000-0002-6099-6415

The past decade was marked, among other things, by the rapid growth of social networks. These networks collect personal data about their users - their photographs, interests, friends, locations, website visits, clicks, status updates and much more. A large number of users and a big collection of various data collected about the users make social media networks an abundant source of data that can be analyzed and used for targeted marketing, social phenomena analysis, generating different statistics and so on. In this paper we will use the potential of the tool RapidMiner in order to collect data from the social media network Twitter using the AYLIEN extension, preparing the data and applying sentiment analysis, which will give insight into the general atmosphere surrounding the actions of the current USA president Donald Trump

The problem of nonperforming loans is one of the biggest problems in the banking sector. In order to mitigate this problem, it is necessary to improve the methods of credit risk assessment. One way to minimize credit risk is to improve the assessment of the creditworthiness of the applicant. In order to make a more accurate assessment, many models have been developed using classification techniques. This paper demonstrates the use of classification techniques in the form of a single classifier or in a classifier ensemble setting. We proposed bagging as a model ensemble using artificial neural networks. In the experiment conducted with the Bosnian commercial banks dataset, the proposed model showed promising results according to evaluation criteria, especially after the process of feature selection. Both individual and wrapper feature selection methods were used. Bagging with neural network (NNBag) outperforms commonly used techniques with accuracy improvement from 1% to 5%. The superiority of the proposed model (NNBag) is confirmed on two widely available datasets for assessing creditworthiness. Based on experimental results on three datasets, it is proven that NNBag is suitable for use in the assessment of the creditworthiness of applicants.

Introduction: Malignant ovarian germ cell tumors (MOGCTs) account for 2-5% of all ovarian cancers and among them pure embryonal cell cancer is rare condition (1, 2, 3, 4). Aim: To show successful pregnancy after unilateral salpingooopherectomy and chemotherapy in a girl with embryonal carcinoma of ovary (ECO). Case report: Patient had FIGO stage III c disease. After the surgical removal of the tumour, the patient underwent six cycles of adjuvant chemotherapy with bleomycin, etoposide and cisplatin (BEP). Eight years after chemotherapy she conceived spontaneously. The patient went through regular antenatal checkups in a consultation with a gynecological oncologist. In addition to all regular examinations and controls, monthly monitoring of carbohydrate antigen (CA) 125, human epididymis protein 4 (HE 4), Roma Index is also recommended. Congenital malformation excluded at 20 weeks of gestation by level III ultrasonography. At 39th gestational week, laparotomy as well as a C-section was done and the patient was managed successfully in giving birth to a healthy female baby. Three months after delivery, the woman was recurrence free and the infant did not show any problems. At the last follow-up visit (May 5, 2018), all the tumor markers were negative, and the control MRI and ultrasound examinations did not reveal tumor recurrence or pathological lymph nodes. Conclusion Normal gonadal function and fertility are possible after fertility preservation surgery for ovarian germ cell malignancies, even with adjuvant chemotherapy.