As traditional museums migrate to the virtual world, they offer wider access to the exhibit collections but often fail to present content of those collections in more engaging way. Game-based learning is one of the solutions to mitigate this inevitable transition and support active learning in the process. It is increasingly gaining interest from the cultural heritage scientific community for the purpose of promoting cultural heritage, raising awareness of its importance and motivating users to visit cultural institutions such as museums more often. There are numerous examples of serious games that are based on or contain heritage content. Tangible cultural heritage is more represented in the virtual worlds and mainly based on applications of 3D technology. Recently, intangible cultural heritage is gaining more visibility within cultural heritage scope as a domain in which game-based learning could assist in its preservation. This paper attempts to address pros and cons of game-based learning in general and reflect on the choices of using serious games in the museum environment.

Industrial manufacturers are innovating their business models by shifting from selling products to selling outcome‐based services, where the provider (manufacturer) guarantees to deliver the perfor ...

Der Aufsatz befasst sich mit der Perzeption des Raumes in deutschsprachigen Reiseberichten über Montenegro aus der ersten Hälfte des 19. Jahrhunderts. In sechs Reiseberichten, die in der Zeit, als Njegoš regierte (1830–1851), entstanden sind, wurden maßgebliche Aspekte der Darstellung des Raumes untersucht und identifiziert, die das Bild Montenegros als exotisches Land transportieren, unabhängig davon, ob der Exotismus als Form der Fokussierung auf das Fremde positiv oder negativ konnotiert ist. Es wurde festgestellt, dass der Exotismus der Darstellung des Raumes Montenegros in den interpretierten und analysierten Texten vor allem auf der Diskrepanz zwischen dem Bestreben einer objektiven Darstellung und der subjektiven Wahrnehmung des Erzählers basiert. Die beschriebenen geographischen Strukturen werden anhand unterschiedlicher literarischer Mittel als exotische, andere, merkwürdige, bedrohliche oder arkadische Wildnis semantisiert, womit Montenegro bis tief ins 20. Jahrhundert assoziiert wurde.

Brassica oleracea L. var. acephala ABA biosynthesis genes (NCED2 and NCED3) in silico interactome analysis

Growing problem of card payment fraudulent abuse is a main focus of banks and payment Service Providers (PSPs). This study is using naive Bayes, C4.5 decision tree and bagging ensemble machine learning algorithms to predict outcome of regular and fraud transactions. Performance of algorithms is evaluated through: precision, recall, PRC area rates. Performance of machine learning algorithms PRC rates between 0,999 and 1,000 expressing that these algorithms are quite good in distinguishing binary class 0 in our dataset. Amongst all algorithms best performing PRC class 1 rate has Bagging with C4.5 decision tree as base learner with rate of 0,825. For prediction of fraud transactions with success of 92,74% correctly predicted with C4.5 decision tree algorithm.

Objective/Purpose: The purpose of this work was the assessment of the clinical efficacy and safety of Bioapigyn® vaginal ointment for pelvic muscle tonus compared to pelvic floor muscle training in alleviating the symptoms of stress, urge and mixed urinary incontinence and vulvo-vaginal disorders in child-bearing and menopausal & postmenopausal women. Materials and Methods: The experimental group consisted of 66 women was treated 28 days with Bioapigyn® ointment for pelvic muscle tonus (2.5 mL/day). The control group also consisted of 66  participants was subjected to pelvic floor muscle training during 28 days (five times a day). ICIQ-UI SF score, the residual urine volume, perineometry, the total score of vulvo-vaginal symptoms and vaginal pH were determined before and after the treatment or training. Results: Following the treatment with Bioapigyn® ointment ICIQ-UI-SF score decreased 54.9%, perineometry parameters  increased  between  31.5  and  34.3%,  residual  urine  decreased  for 76.9%  and  vaginal  pH  for 14.2%. All the symptoms of vulvo-vaginal disorders disappeared completely in all participants. The control group showed no changes in vaginal pH or the improvement concerning the vulvo-vaginal complaints. ICIQ- UI-SF score decreased for 4.3%, residual urine volume for 9.1% while perineometry parameters increased between 4.3 and 8.3%. Conclusion/Discussion: Bioapigyn® vaginal ointment for pelvic muscle tonus alleviate the symptoms of incontinence by tightening and firming of the smooth muscles of the pelvic floor thanks to the ingredients with smooth muscles contraction/relaxation and astringent properties. Low pH, high osmolarity, viscosity, greasiness and coating effect of the ointment eradicated vulvo-vaginal complaints.

This article was elaborated based on a study for the optimization of routes between 19 establishments and two entrances in the city of Jaboticabal, in the interior of São Paulo. Your purpose was to explored the possible routes for improvement to identify the pathway. To perform this work we used bibliographic research in books and articles on the Internet and the solution of the proposed problem was done through Microsoft Excel spreadsheet and its tool Solver using the Evolutionary method. With the analysis of the results it was possible to observe which the best way to be chosen. As companies nowadays need fast logistics distribution, it is concluded that the use of computation tools such Excel Solver is essential for information optimization and decision making aid, thus generating lower costs for companies