The EU has long been suffering a legitimacy crisis. In this article we argue that multilingual Europarties, that is, European political parties operating in all the various languages spoken by their members via interpreting and translation, rather than resorting to a lingua franca, could contribute to providing an effective democratic linkage between EU citizens and EU institutions. Moreover, by drawing inspiration from an analysis of Belgium, Canada and Switzerland, we argue that centripetal institutions such as an EU-wide electoral district, presidentialism, and direct democracy could provide favourable institutional conditions for the development of such multilingual Europarties.
We present a simple method to quickly explore C-spaces of robotic manipulators and thus facilitate path planning. The method is based on a novel geometrical structure called generalized bur. It is a star-like tree, rooted at a given point in free C-space, with an arbitrary number of guaranteed collision-free edges computed using distance information from the workspace and simple forward kinematics. Generalized bur captures large portions of free C-space, enabling accelerated exploration. The workspace is assumed to be decomposable into a finite set of (possibly overlapping) convex obstacles. When plugged in a suitable RRT-like planning algorithm, generalized burs enable significant performance improvements, while at the same time enabling exact collision-free paths.
Mechanisation used in forest utilisation has an impact on the occurrence of damage in stand and on forest land. The research in this work had the objective of determining damage on fir trees and other tree species during felling and processing of trees and their skidding using the forest cable-skidder. The research wasconducted in mixed beech and fir forests in the area of FMA “Glamočko”, M.U. “Hrbinje-Kujača”. The following data were gathered on damaged trees: tree type, breast height diameter, economic importance of the tree, amount of damage, location of damage, cause of damage, types of damage. Damage was recorded on a total of 305 trees, 133 trees of silver fir (Abies alba), 130 trees of European beech (Fagus sylvatica), 33 trees of European spruce (Picea abies), 8 trees of rowan/mountain-ash (Sorbusaucuparia) and one tree of sycamore (Acer pseudoplatanus). The overall damage intensity was 18.7%, but together with the old damages, the overall number of ‘wounds’ is 496. According to this, when the old damage isalso considered, then the intensity of damage amounts to 30.6%. The largest amount of damage is in the diameter sub-class ranging from 10 to 14.99 cm. According to the cause of damage, the largest amount of damage occurred during the wood extraction phase (217 trees), while during the felling phase, 88 trees or 29% were damaged. Since the wood extraction phase is divided into the winching and skidding phases, the total number of damaged trees during the winching phase amounted to 157 or 52%, while during the skidding phase, the number of damaged trees was 60 or 19%. To reduce damage to the trees during following operations in forest utilisation, it is necessary to perform more frequent training of all employees working on forest utilisation, to increase controls in execution of operations during forest utilisation, modernise machines used during forest exploitation, and in quality manner open compartments with forest road infrastructure.
Under the AKP government, Turkey’s foreign policy towards the Western Balkans, and Bosnia and Herzegovina in particular, has led many analysts to suspect it of possessing neo-imperial, or so-called neo-Ottoman, objectives. These suspicions have been compounded by the repeated declarations of former Prime Minister Davutoğlu and current President Erdoğan that the history and religious identity shared by Turks and Western Balkan Muslims forms the basis of both Turkish-Balkan relations and a common future. Critical examination of official Ankara’s attitudes toward the Western Balkans in general, and especially Bosnia and Herzegovina, identifies four distinct phases in which cultural, historical, and religious appeals morphed into the set of distinctive foreign policies. These policies have also been shaped by pragmatic pursuits of regional influence, the effects of internal (Turkish) transformations, and more recently, the ad hoc policies of President Erdoğan. This article will reconstruct the development of Turkish foreign policy since 1990, from multilateral and soft power efforts to religious and economic objectives, and will analyse the limits of this policy.
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by major social, communication and behavioural challenges. The cause of ASD is still unclear and it is assumed that environmental, genetic and epigenetic factors influence the risk of ASD occurrence. MicroRNAs (miRNAs) are short 21–25 nucleotide long RNA molecules which post-transcriptionally regulate gene expression. MiRNAs play an important role in central nervous system development; therefore, dysregulation of miRNAs is connected to changes in behaviour and cognition observed in many disorders including ASD. Based on previously published work, on diagnosing ASD using miRNAs, we hypothesized that miRNAs can be used as biomarkers in children with suspected developmental disorders (DD) including ASD within Bosnian-Herzegovinian (B&H) population. 14 selected miRNAs were tested on saliva of children with suspected developmental disorders including ASD. The method of choice was qRT-PCR as a relatively cheap method available in most diagnostic laboratories in low to mid-income countries (LMIC). Out of 14 analysed miRNAs, 6 were differentially expressed between typically developing children and children with some type of developmental disorder including autism spectrum disorder. Using the most optimal logistic regression, we were able to distinguish between ASD and typically developing (TD) children. We have found 5 miRNAs as potential biomarkers. From those, 3 were differentially expressed within the ASD cohort. All 5 miRNAs had shown good chi-square statistics within the logistic regression performed on all 14 analysed miRNAs. The accuracy of 5-miRNAs model training set was 90.2%, while the validation set had a 90% accuracy. This study has shown that miRNAs may be considered as biomarkers for ASD detection and may be used to identify children with ASD along with standard developmental screening tests. By combining these methods we may be able to reach a reliable and accessible diagnostic model for children with ASD in LMIC such as B&H.
This paper presents a framework capable of accurately forecasting future sales in the retail industry and classifying the product portfolio according to the expected level of forecasting reliability. The proposed framework, that would be of great use for any company operating in the retail industry, is based on Facebook's Prophet algorithm and backtesting strategy. Real-world sales forecasting benchmark data obtained experimentally in a production environment in one of the biggest retail companies in Bosnia and Herzegovina is used to evaluate the framework and demonstrate its capabilities in a real-world use case scenario.
The goal of the paper is to derive some approximate formulas for the logarithmic derivative of several zata functions of Selberg’s type for compact symmetric spaces formed as quotients of the Lie group SL4 (R). Such formulas, known in literature as Tutchmarsh-Landau style approximate formulas, are usually applied in order to obtain prime geodesic theorems in various settings of underlying locally symmetric spaces.
Abstract Introduction. Bladder cancer is the most common malignancy involving the urinary system. Recent research tends to emphasize the role of oxidative stress products in the carcinogenesis of bladder cancer. The level of oxidative stress can be measured by assessing the MDA levels. This study aimed to evaluate serum MDA levels in patients with bladder cancer, as well as to determine its potential role as a biomarker in the diagnosis of the disease and progression risk considerations. Methods. The study was designed as a cross-sectional study and included 90 patients, divided into three groups with 30 patients each: Ta, T1and T2–T4 group, based on histopathological findings after transurethral resection of the tumor. The control group included 30 healthy volunteers. MDA level was determined using the spectrophotometric method. Results. Serum MDA level in patients with bladder cancer [0.86 (0.78–1.05) μmol/L] was significantly higher than the serum MDA level in control group [0.70 (0.69–0.72) μmol/L] (p < 0.001). Serum MDA level in Ta group [0.73 (0.70–1.05) μmol/L], T1 group [0.85 (0.80–1.12) μmol/L] and in T2–T4 group [0.91 (0.84–1.04) μmol/L] was significantly higher than the serum MDA level in control group [0.70 (0.69–0.72) μmol/L] (p < 0.01). MDA level in T1 and T2–T4 group was significantly higher than the MDA level in Ta group (p < 0.01). No significant difference was observed in MDA level between T1 and T2–T4 group (p = NS). A statistically significant positive correlation was found between tumor size and serum MDA level in patients with bladder cancer (rho = 0.254 p < 0.01). Conclusions. The results of the present study suggest that MDA serum level might play a significant role as a biomarker in the diagnosis of bladder cancer, as well as in the monitoring of its progression.
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