Coronary artery disease remains among the leading causes of morbidity and mortality in the world. Percutaneous coronary interventions PCI have become the leading mode of revascularization in patients with single-vessel or double-vessel coronary disease, as well as in patients with acute coronary syndrome. For the purpose of optimal treatment of patients in the Republic of Srpska, a cath lab was opened at the Clinic for Cardiovascular Diseases of the University Medical Center of the Republic of Srpska in June 2007. Retrospective data collection in the period from 2007 to 2021 revealed that 33,183 procedures were performed. The opening of the cath lab of the Clinic for Cardiovascular Diseases of the University Medical Center of the Republic of Srpska enabled the application of the most modern methods for diagnosis and treatment of ischemic coronary heart disease, which led to significantly lower mortality rates from STEMI and NSTEMI infarction in Republika Srpska, with significant progress in treating patients with other forms of ischemic heart disease.

We present a case of 55-years old man with severe mitral regurgitation with significantly reduced ejection fraction, paroxysmal atrial fibrillation and hypertension, who underwent surgical procedure of the replacement of the mitral valve.

We present a case of 72-years old patients with long standing heart failure with reduced ejection fraction, diabates mellitus with chornic renal failure and previous CRT implantation, in whom initation of new treatment with empaglifozine and sacubitril valsartin in addition to beta-blockers and diuretics significantly improved hic clinical condirion and laboratory status.

Bosnia and Herzegovina, having an extremely complex state system and at the same time being a developing country and economy in transition with a commitment to membership in the European Union, faces numerous challenges in adapting national legislation to the acquis communautaire. One of the key segments of the introduction of European standards is the establishment of an effective mechanism for the protection of competition in legislative and institutional terms. With the adoption of the Competition Law in 2005, which brings new solutions and is largely in line with the acquis, Bosnia and Herzegovina has made a significant step forward from the previous state of legal irregularity in this important segment. However, sixteen years of the enforcement of the BiH Competition Law have shown certain shortcomings regarding the particular solutions contained in it. These shortcomings concern the part of the provision of the law that regulates procedural issues, but also the functioning of the authority responsible for the protection of competition in Bosnia and Herzegovina and it can be assumed that these are obstructive elements in response to the challenges of COVID-19 pandemic. In order to follow the international trends, companies in BiH have entered into a process of business digitalization, which, however, being accelerated due to COVID-19 pandemic, has created many challenges before the Council of Competition of BiH as the authority responsible for public enforcement of the competition law. The aim of this paper is to question the extent to which COVID-19 pandemic has affected the work of the Council of Competition BiH, as well as to address some of the particular issues it has faced before the pandemic, including growing market concentration, growing power of digital platforms, protectionism, consumer vulnerability and consequent loss of public confidence. In order to meet the set research goals, the first part of the paper will present an analysis of the legal solutions in the context of the legal and institutional aspect of competition protection and will provide an overview of the situation regarding the digitalization of business operations in Bosnia and Herzegovina. The second part of the paper will provide an analysis of the work of the Council of Competition of BiH with special reference to the period of declaring the pandemic COVID-19.

| The aim of this study was to morphologically describe the air sac system in Rosy-faced parrots (Agapornis roseicollis) and provide useful data for future veterinary care and treatment of respiratory system diseases in these pets. The research was conducted on five birds. In order to obtain the casts of the air sacs, we applied the corrosion cast technique, where we used the 26% solution of Vinylite mass. The research showed that the anatomy of the air sacs in these parrots was very similar to that in other birds, but there was some specific characteristic regarding the arrangement and connection between the air sacs. In Rosy-faced parrots we identified nine air sacs, the one unpaired, saccus clavicularis and paired saccus cervicalis, thoracicus cranialis, thoracicus caudalis and abdominalis. The casts showed that clavicular and cranial thoracic air sacs established a connection through the diverticula sternalia. These anatomical characteristics can be common to birds from Psittaciformes order and additional research need to be performed to confirm these findings.

of the age group of 6–12 years, and 10 patients of the age group of 12–18 years. Conclusions: Data suggest that pediatric cases of COVID-19 in adolescents have more severe symptoms than in the other age groups; however, in general children tend to cope much more easily with the virus than adults.

Introduction: Conventional cytogenetics by the use of standard karyotyping allows the study of numerical and structural chromosomal aberrations. Haematological malignancies include a number of cancer types that originate in the blood cells of the bone marrow or of the lymphatic system. Cytogenetic methods are traditionally used for the sake of diagnosis and prognosis of these diseases. However, with the ever more frequent use of molecular methods in the diagnostic laboratories, the importance of the conventional cytogenetic analysis in the diagnosis of haematological diseases needs to be reassessed. Aim: To evaluate the role of cytogenetic methods in the diagnosis of haematological malignancies. Materials and Methods: A retrospective analysis of cytogenetic findings of 146 patients with various haematological malignancies was performed. All of the findings were made over a period of three years at the Centre for Genetics at the Medical Faculty of the University of Sarajevo in Bosnia and Herzegovina. Microsoft Excel 2019 was used for the analysis and presentation of data in the form of tables and graphs. Results: The results of the present study showed that the use of conventional cytogenetic analysis is a good diagnostic method for 50.68% (74) of patients in whom chromosomal aberrations were detected. Conclusion: Cytogenetics remains the most comprehensive method for assessing chromosomal abnormalities due to its ability to detect clinically relevant aneuploidies and additional cytogenetic abnormalities that cannot be detected by locus-specific assays.

There is a view that playing sports is positively related to pupils' academic achievement. Results of studies worldwide indicate this correlation, while few studies have been done in Bosnia and Herzegovina on this problem. The current study aims to expand on findings from previous studies by examining associations between (1) mode: active vs. recreational); (2) type: individual vs. team based and (3) a particular kind of sports and academic achievement particularly math achievement among middle school children. Population involves middle school pupils in two urban areas in Bosnia and Herzegovina and research sample consists of 1036 female and 1055 male pupils wanting to take part in study voluntarily. Kruskal-Wallis and Wilcoxon test were conduced to obtain results. Results show that middle school pupils who are actively involved in sports have better overall midterm academic success as well as better mathematics achievement compared to those who are involved in sports recreationally or not at all (p < 0.001). On the other hand, differences do not occur between pupils who are engaged in team or individual sports. Also, pupils who practice football were found to have lower school performance compared to pupils who practice some of the other sports.

The purpose of this research is to provide some insights into socio-demographic determinants of predicting the likelihood of residents propensity to travel. Using the quota sampling technique, data collection was carried out from October to December 2019, yielding a sample of 632 valid responses. To gain a better understanding of the sociodemographic determinants of propensity to travel, we, primarily, use descriptive statistical analysis, chi-square test and probit regression model. The research findings have revealed that age, education and household income characteristics may be considered as antecedents of travel propensity of residents. Having in mind the impact that Covid-19 pandemic has on sector of tourism worldwide, and based on the results of this research, policymakers' efforts should be directed to promoting local tourist destinations and to enhancing tourism literacy of residents.