Buildings, although one of the largest energy consumers in the world, also represent big potential to reduce energy consumption, dependence on fossil fuels and carbon dioxide emissions, through the implementation of energy efficiency measures. Improvement of energy efficiency of existing buildings requires a dedicated, serious and detailed approach. Investors are often guided by economic criteria, which greatly influence on investments and interventions, potentially causing some negative side effects (comfort reduction, use of energy-intensive materials, etc.). Therefore, it is very important to rely on methods that provide detailed and affordable cost, technical and environmental analysis. Energy efficiency methods are often based on simple methods such as research, estimation of energy consumption, preliminary design, estimation of energy savings and financial cost-effectiveness. For example, in energy audits of buildings, annual energy consumption and cost-effectiveness are considered for analysis. For a more detailed assessment, a calculation tool based on the calculation of energy consumption of particular facility and the estimation of energy savings after the proposed energy efficiency measures is being used. The proposed measures generally represent a classic scenario of energy efficiency measures. In this paper, factors such as comparison of the share of fossil fuels and renewable energy sources (RES), the estimation of cost-effectiveness of the use of renewable energy technologies, aspect of embodied energy in materials and life cycle assessment in buildings are being considered. This paper defines the criteria for the evaluation of scenarios (functional groups of measures) for increasing energy efficiency of the building, which include, in addition to energy and economic aspects, environmental aspect. The six criteria have been defined for evaluation of energy efficiency scenarios related to: annual energy consumption, total annual primary energy, share of RES in primary energy, direct and indirect carbon emissions, embodied energy in applied materials and investment per scenario. For each criteria an expression for its calculation is given. Defined criteria are calculated for six scenarios of increasing the energy efficiency of Mechanical Engineering Faculty, University of Sarajevo. Based on the calculated different values of criteria of considered aspects, it is possible to identify in more detail way critical points, advantages and disadvantages of different combinations of energy efficiency measures, which can further serve to identify the best strategy necessary for evaluation of energy performance of the building before and after the intervention.

Contemporary tendencies of sustainable and energy-efficient architecture imply an urgent reconsideration of society’s relationship to nature. Nowadays, building technology demands a responsible approach to construction that involves fostering of low-tech architecture, as an alternative to high-tech architecture. Those are current challenges that architects and the building technology face to improve the application of natural materials in architecture. The necessity for advancement and contemporary usage of building materials as wood, stone, soil, straw, natural insulation materials have also resulted in the increasingly present low-tech architecture. This research aims to delineate through several contemporary case studies how serious global problems related to the energy and environmental crisis are increasingly reflected in the intention towards the use of natural materials in the architectural design. These contemporary designs implement innovative solutions of natural materials in the case of building envelopes, construction details or structural elements. The comparative analytical method involves a critical reflection on the integration of natural materials between traditional vernacular application and its contemporary innovative solutions. These contemporary precedents represent diverse design approaches that reinforce the importance of environmental and ecologically responsible design. Current problems related to the energy and environmental crisis highly influence the underlying design concepts and final building design. The contemporary usage of natural materials as a building resource indicates the evolving advancement and re-evaluation of an ecologically responsible architecture. Whereas the contemporary ways of integrating natural materials carry universal values which originate from the principles of vernacular architecture.

The transitional process from a socialist into a capitalist societal system, started at the end of the twentieth century in Bosnia and Herzegovina, and the related transformation of the public into private land ownership, with the neglect and lack of adequate development programs and public opinion, produce today the urban-architectural and, in general, identity crisis. Under the guise of overall well-being, but mostly in the service of short-term economic profit, attractive urban spaces are occupied, the existing physical structure is uncontrollably removed and new construction is carried out, almost as a rule, in disregard for the needs and interests of society/citizens. Transformations of urban space, generated by the vibrations of a transitional society, are most evident in the capital, Sarajevo. The building process is basically a multiplication of residential settlements, the construction of which is carried out on a case-by-case basis, with considerable pressure from investors, and with the decisions made within closed, narrow interest circles and (often) without consulting the profession/urban planners and the public/citizens. In such an environment, the public domain loses its primacy over the private, which is manifested in the alienation of people and the loss of their identification with the place. Such residential settlements are deprived of central functions in the field of social infrastructure and in the manner of “tried and tested” repetitive urban-architectural models, which together negatively affect the quality of individual and social life. In other words, residential settlements without an identity are created. Although they have formal names, these settlements are nameless. They are no places. Architecture and building are always deeply connected with the ideological framework of a particular society, which means that the understanding of the function of space and the place of man in it, we have opened a central question, as the main goal of this paper: Is it really true that the construction of Sarajevo’s new settlements cannot be adapted to anything other than current urban policy? Or else: Is their fate such that they will be permanently determined by the attribute of a settlement without a name? For the purpose of finding the answer, of possible ways of overcoming the crisis or at least mitigating its effects, we conducted a comparative analysis of housing planning in a socialist societal system with current transition planning. The results of this analysis have shown that the new urban policy is intrinsic and creates new articulations of urban space without spatial identity, essentially a name. We have concluded that a crucial moment has arisen in which it is necessary to stop anarchic decision-making on (sporadic) transformations of the city space and to establish a system of compliance with procedures in designing and adopting programs that allocate new necessary functions within the existing physical structures. As urban decisions are currently being made (mostly) outside the realm of the public/citizens, i.e. in closed circles and with the pressures of private investment, the need to change such practices is evident. This is only possible through dialogue, because when all those interested in the decision-making process are involved in the conversation, then change will happen. Only then will we be able to talk about urban politics dedicated to creating an environment in which a person, is placed in the centre of the building process, and where one is given the opportunity to personalize the space one inhabits, to identify with and name it – make it its own, personal and intimate.

Spatial typologies in urbanism and architecture within the City of Sarajevo are inherently complex and differentiated. Throughout the history of the city, the architectural and urban typologies have been evolving and adapting to new circumstances, but in several historical periods, the changes of typologies have been radical. From the fifteenth century, Sarajevo was organized by the oriental ottoman typological scheme that shaped the city for several centuries: organic forms, human and intimate scale, commercial and residential areas quite strictly separated. During the nineteenth century, a central-European urban and architectural typology dominated and morphed the city in a radical new way. Introduction of the larger scale buildings organized in blocks, with mixed functions. The usual typological transformation was taken over by a process of replacement with completely new forms, yet the city seemed to inherently adapt to these new conditions owning this new typology. Introduction of modernist typologies within the realm of the city was also a radical break from the past - functionalist dispersed buildings with open green areas again became a logical part of the city. The new transitional period has brought about new challenges and generated buildings (commercial and residential) with questionable typologies. Current tendencies are lacking in many parameters that define a certain typology - a coherent idea and spatial logic. Can one city inherently possess the ability to adapt and transform such different variations of typologies and claim authenticity? Is there a typology most suited to this place? Ever since the typological research was introduced to architectural theory by De Quincy in 1825, there was the notion of origins of typology, transformation and novelty/innovation. This paper will conduct a research of historical and current spatial typologies (architectural and urban schemes), in order to answer the question is the typology inherent, born out of a certain place or does the place affect, change the typology? The research would be about the correlation between a city (Sarajevo), the capacity of space and relevant parameters of typologies (scale, forms, functions, adaptation).

The volumetric flow rate (injection velocity) and the holding pressure are metal injection molding (MIM) parameters that have a strong influence on the green parts density and density homogeneity, but their effect on sintered dimensions after sintering is still to a large extent unexplored. To reveal the relationship between the injection molding parameters and sintered dimensions, ring-shaped components were injection molded by using different values of injection velocities in combination with a rump-down and rumpup holding pressure profile. Afterwards, the green components were catalytically debound and sintered in the nitrogen (N2) atmosphere. Finally, the component dimensions: the height, inner and outer diameter were measured by using a coordinate measuring machine. The ready-to-mold granules Catamold 310N made of heat resistant stainless steel X40CrNiSi 25-20 (according to the EN standard) powder and polyacetal based binder were used. The results showed that the interaction between the injection velocity and the holding pressure profile can be used to systematically adjust shrinkage after sintering. This approach is based on the dependence of the binder crystallization temperature on pressure, when the powder/binder proportion changes with the injection velocity.

concept and and/or assembly of data; data analysis and interpretation; Research on moderate-intensity continuous training (MICT) is closely connected with primary and secondary cardiovascular protection but also can be associated with primary bypass patency and outcome of endovascular treatment for critical iliac stenosis TASC II A and B. After specific surgical or non-surgical treatment, iliac bypass or endovascular revascularization patency still depends on an individual and is still in the eye of scientific research modalities. Carotid intima-media thickness (CIMT) is an efficient surrogate parameter in detection and prediction of cerebrovascular events and potential marker of generalized atherosclerosis with prognosis of peripheral arterial disease related to prognosis of atherosclerotic coronary hemodynamic pathology. Materials and methods. A total of 139 patients were observed during 4 years of MICT. Ultrasonography of the distal part of the common carotid artery (CCA) was performed to measure CIMT before and after revascularization procedure. The bypass patency and walking distance was also studied. Results. In the total population, no difference in changes of CIMT from baseline was observed between the standard exercise group and controls in 4 years. However, there was a significant correlation between the effect of exercise training and CIMT within 4 years. CIMT was not significantly reduced in the exercise group compared with control non-diabetic patients. Conclusions. Exercise training in both groups did not significantly change carotid intima-media thickness in the four years following endovascular procedure and Dacron bypass revascularization, but significant beneficial effect of moderate-intensity continuous training on bypass patency was observed in patients with mild or without claudication symptoms as well as on subjective and objective health status.

Introduction: Aim of the study is to piloting nursing documentation to obtain comments based on the experience of nurses/medical technicians from the primary, secondary, and tertiary health care about the documentation before it is published and starts being used.Methods: A questionnaire was designed in the electronic form to be used for the evaluation and suggestions by nurses/medical technicians on the piloted form and content of nursing documentation for all levels of health care. A piloting sample was prepared to make 10% of nurses/medical technicians from health care institutions from the territory of the Federation of Bosnia and Herzegovina.Results: A total of 94.3% of examinees at the primary health care level and only 17.2% of the examinees in the secondary and tertiary health care fill out nursing documentation both manually and electronically. All examinees at all levels of health care understand the purpose and importance of nursing documentation. A total of 27.7% of the examinees at the primary and 40.9% of the examinees at the secondary and tertiary level of health care pointed out that filling out nursing documentation was too time-consuming.Conclusion: A total of 51.2% of the examinees at the primary and 64.2% at the secondary and tertiary level of health care agreed that submitted nursing documentation was adequate for use. It is suggested that after the adoption of nursing documentation at all levels of health care, piloting of its use should be conducted to evaluate the quality and quantity of all nursing documentation.

We present a realization of a didactic robot environment for robot PUMA 560 for educational and research purposes. Robot PUMA 560 is probably the mathematically best-described robot, and therefore it is frequently used for research and educational purposes. A developed control environment consists of a robot controller and teach pendant. The advantage of using a personally developed solution is its open structure, which allows various tests and measurements to be performed, and that is highly convenient for educational and research purposes. The motivation behind the design of this personal didactic robot control environment arose from a survey for students after the first Summer School on Mechatronic Systems. The student questionnaire revealed severe discrepancies between theory and practice in education. Even though the primary purpose of the new control environment for robot PUMA 560 was research, it was established that it is a viable lab resource that allows for the connection between theoretical and industrial robotics. It was used for the duration of four Summer Schools and university courses. Since then, it has been fully integrated into International Burch University’s Electrical and Electronics Engineering curriculum through several courses on the bachelor and master levels for multidisciplinary problem-based learning (PBL) projects.

Kajmak ist ein traditionelles Milchprodukt mit einer spezifischen Zusammensetzung und besonderen sensorischen Eigenschaften. Seine Herstellung erfolgt in ländlichen Haushalten und basiert auf einem traditionellen Verfahren. Die traditionelle Herstellung von Kajmak ist in Bezug auf die Art der Zubereitung sehr unterschiedlich, was zu großen Unterschieden in der Zusammensetzung, den Eigenschaften und der Qualität des Produkts führt. In der Verordnung über Milchprodukte und Starterkulturen ("Amtsblatt von Bosnien und Herzegowina", Nr. 21/11 und 17/19) in Abschnitt "H Kajmak" sind die grundlegenden Bestimmungen für Kajmak auf dem Markt von Bosnien und Herzegowina enthalten. Die Aufgabe dieser Arbeit besteht darin, den Unterschied zwischen industriellem Kajmak und Kajmak, der nach einer traditionellen Rezeptur und unter kontrollierten Produktionsbedingungen hergestellt wird, zu bestimmen und zu prüfen, ob die auf dem Markt befindlichen Produkte den gesetzlichen Vorschriften entsprechen. Die Proben für sensorische und chemische Analysen wurden aus den Regalen der Geschäfte in Bosnien und Herzegowina entnommen. Es wurden drei Sorten von industriellem Kajmak getestet sowie der unreife und reife Kajmak, der nach einem traditionellen Verfahren unter kontrollierten Bedingungen hergestellt wurde. Zweck dieser Untersuchung bestand darin, herauszufinden, was den Verbrauchern unter der Deklaration des Produktes angeboten wird, die sensorischen Eigenschaften des Produkts zu bewerten und das Produkt auf der Grundlage der erzielten Ergebnisse in eine bestimmte Gruppe abhängig von seiner Qualität einzuordnen. Nur eine der fünf untersuchten Proben entsprach den gesetzlichen Bestimmungen, die in Bosnien und Herzegowina in Kraft sind. Kajmak ist ein delikates Produkt, dessen Herstellung viel Aufmerksamkeit erfordert, und es stellt sich die Frage, ob die gesetzlichen Vorschriften zu streng sind oder ob die Hersteller der Art und Weise, wie dieses Produkt hergestellt wird, nicht viel Aufmerksamkeit schenken.

The kinetics of passive transport of ketoprofen and metformin, as model substances for high and low permeability, respectively, across the artificial membrane under the influence of the pH of donor solution was investigated. There was an upward trend in the apparent permeation coefficient (Papp) of ketoprofen with the decrease in pH to a value close to pKa. At the pH value below pKa the permeation coefficient had lower value, due to the higher retention of ketoprofen in the artificial membrane. Metformin is a low permeable compound, and the highest permeation values were recorded at pH 7.4. Two dissociation constants determine that metformin at physiological pH exists as a hydrophilic cationic molecule, i.e. predominantly in ionized form. At pH values below 2.8, metformin mainly exists in diprotonated form, and it was, thus, very poorly permeable. The highest retention, i.e. affinity of both ketoprofen and metformin to the membrane, was at the lowest pH values, which is explained by different mechanisms. At higher pH values of donor compartment the substances showed significantly less affinity to the membrane. The obtained values of apparent permeation coefficients at studied pH values showed good correlation with the obtained experimental values by other in vitro methods.

Castleman disease (CD) includes a group of rare and heterogeneous disorders with characteristic lymph node histopathological abnormalities. CD can occur in a single lymph node station, which is referred to as unicentric CD (UCD). CD can also involve multicentric lymphadenopathy and inflammatory symptoms (multicentric CD [MCD]). MCD includes human herpesvirus-8 (HHV-8)-associated MCD, POEMS-associated MCD, and HHV-8-/idiopathic MCD (iMCD). The first-ever diagnostic and treatment guidelines were recently developed for iMCD by an international expert consortium convened by the Castleman Disease Collaborative Network (CDCN). The focus of this report is to establish similar guidelines for the management of UCD. To this purpose, an international working group of 42 experts from 10 countries was convened to establish consensus recommendations based on review of treatment in published cases of UCD, the CDCN ACCELERATE registry, and expert opinion. Complete surgical resection is often curative and is therefore the preferred first-line therapy, if possible. The management of unresectable UCD is more challenging. Existing evidence supports that asymptomatic unresectable UCD may be observed. The anti-interleukin-6 monoclonal antibody siltuximab should be considered for unresectable UCD patients with an inflammatory syndrome. Unresectable UCD that is symptomatic as a result of compression of vital neighboring structures may be rendered amenable to resection by medical therapy (eg, rituximab, steroids), radiotherapy, or embolization. Further research is needed in UCD patients with persisting constitutional symptoms despite complete excision and normal laboratory markers. We hope that these guidelines will improve outcomes in UCD and help treating physicians decide the best therapeutic approach for their patients.