Introduction: Sudden OHCA (Out of hospital cardiac arrest) is the third leading cause of death in industrialized nations. With more than 60% of cardiovascular deaths resulting from cardiac arrest, it remains the leading cause of death worldwide. Heart rhythms associated with cardiac arrest are divided into two groups: shockable rhythms (ventricular fibrillation/pulseless ventricular tachycardia (VF/pVT) and non-shockable rhythms (asystole and pulseless electrical activity (PEA)). VF is the most commonly identified arrhythmia in cardiac arrest patients. Urgent medical treatment includes cardiopulmonary resuscitation and early defibrillation. Material and Methods: Materials for this case report are data collected from the medical records of the Emergency Medical Center of Sarajevo protocol of patients. Case report: Our case report is presented with 59 years old man who had OHCA in his apartment. The initial rhythm was VF, and cardiopulmonary resuscitation was provided due to the Advanced life support guidelines to shockable rhythms. It was delivered 3 DC Shock-s (200J, 300J, 360 J) with the biphasic defibrillator, it was administered 1mg Adrenalin and performed endotracheal intubation. After the third DC shock, we got the return of spontaneous circulation ROSC. The patient was transferred to the University hospital, were he was stabile, and PCI of the LAD was performed as per the standard protocol. Echocardiography performed in the CCU revealed hypokinesia of RV, with preserved systolic function. On hospital day 7 he had a full neurological recovery. He was conscious, oriented, with normal breathing, blood pressure 125/79mmHg, sPO2 99, ECG: sinus rhythm, fr 87/min, without pathological signs. Echocardiography revealed the reduced systolic function of the left ventricle, with mitral regurgitation MR+2. Discussion: Out-of-hospital cardiac arrest (OHCA) is a major health problem in Europe and in the United States. The numbers of patients who have OHCA annually in these two parts of the world have traditionally been reported to be 275,000 and 420,000 respectively. The success of resuscitation depends on many factors: well-organized health care, organization of outpatient emergency services, but primarily when it comes to OHCA, education of the population on Basic life support, and early Cardiopulmonary resuscitation and use of AED (automated external defibrillator).
A 12-point checklist in the design and practical application of active surveillance of diseases in aquatic organisms (farmed and wild) has been developed to serve as a methodological approach and guidance for a multidisciplinary team particularly in countries where surveillance expertise is limited. The checklist is based on a review of available main aquatic surveillance references and scientific literature and was further developed based on the outcomes of several aquaculture biosecurity project-related workshops hosted by the Food and Agriculture Organization of the United Nations. The checklist includes the following: (1) scenario setting; (2) defining surveillance objective; (3) defining the populations; (4) disease clustering; (5) case definition; (6) diagnostic testing; (7) study design and sampling; (8) data collection and management; (9) data analysis; (10) validation and quality assurance; (11) human and financial resources and logistics requirements; and (12) surveillance in the bigger picture. For a multidisciplinary approach to disease control, knowledge of fish biology, aquaculture systems and many aspects of aquaculture health management are required. Surveillance needs significant financial investment and must be supported by adequate diagnostic capability, information system management, legal framework and communication networks, with transparent reporting mechanisms to allow rapid disease response for serious diseases of aquatic organisms. It is a stepwise and pragmatic approach that offers a good starting point for addressing disease issues especially in developing countries. It can be used as a model to build targeted surveillance competency and a basic reference when implementing a surveillance programme or improving existing programmes.
As the number of road accidents are increasing, it constitutes to increased human loss during many instances. Accidents will primarily occur due to rash driving, over speed and other related parameters. Hence, it develops an increased necessity to avoid the road accidents and save the human lives. Based on the principles of Internet of Things (IoT), Artificial Intelligence (AI), and Digital Image Processing (DIP), a Vehicular Safety Device (VSD) is proposed and developed in this paper. The developed device will include four main features like anti-dash system, anti-rash driving, anti-over speeding and anti-sleep alert system to safeguard the drivers and passengers from road accidents. This combination of safety technologies are designed and considered as a human look-alike by using various advanced technological interventions. These devices are imbibed with various supporting systems like Global Positioning System (GPS) and Global System for Mobile Communication (GSM) modules, which provides a real-time location to track and monitor the vehicle by respective authority. The proposed system has various tools like AI enabled camera with digital image processing architecture to autonomously monitor the driver. The device also has some additive features like total vehicle health report, wherein the users can download the details about vehicle movement. The proposed technology can be effectively used for improving and safeguarding human lives for developing a better future.
The object of the research are fuzzy functional dependencies on given relation scheme, and the question of their obtaining using the classical and innovated techniques. The attributes of the universal set are associated to the elements of the unit interval, and are turned into fuzzy formulas in this way. We prove that the dependency (which is treated as a fuzzy formula with respect to appropriately chosen valuation) is valid whenever it agrees with the attached two-elements fuzzy relation instance. The opposite direction of the claim is proven to be incorrect in this setting. Generalizing things to sets of attributes, we prove that particular fuzzy functional dependency follows form a set of fuzzy dependencies (in both, the world of two-element and the world of arbitrary fuzzy relation instances) if and only if the dependency is valid with respect to valuation anytime the set of fuzzy formulas agrees with the valuation. The results derived in paper show that the classical techniques in the procedure for generating new fuzzy dependencies may be replaced by the resolution ones, and hence automated. The research is conducted with respect to Willmott fuzzy implication operator
In this paper we consider all possible dependencies that can be built upon similarity-based fuzzy relations, that is, fuzzy functional and fuzzy multivalued dependencies. Motivated by the fact that the classical obtaining of new dependencies via inference rules may be tedious and uncertain, we replace it by the automated one, where the key role is played by the resolution principle techniques and the fuzzy formulas in place of fuzzy dependencies. We prove that some fuzzy multivalued dependency is actively correct with respect to given fuzzy relation instance if and only if the corresponding fuzzy formula is in line with the attached interpretation. Additionally, we require the tuples of the instance to be conformant (up to some extent) on the leading set of attributes. The equivalence as well as the conclusion are generalized to sets of attributes. The research is conducted by representing the attributes and fuzzy dependencies in the form of fuzzy formulas, and the application of fuzzy implication operators derived from carefully selected Frank’s classes of additive generators
From the point of view of syntactic analysis, the main features of texts belonging to literary style are the unlimited freedom and absence of rules which in other functional styles dictate the characteristic use of syntactic patterns and structures, as well as means of text cohesion. That is why it is difficult to discuss the specific features of the syntax of literary style in general. Instead, it is possible to analyze the use of syntax as an element of style of individual authors, literary movements or genres. However, it is not the syntactic features that could be analyzed as building blocks of unique, homogenous style of Yusuf Idris that served as motivation for writing of this paper. Quite the contrary, the paper draws attention to markedly different syntactic devices used by this writer in different short stories. The central focus of the paper is the analysis of these syntactic devices in several short stories of Yusuf Idris, which aims to show that the use of syntax therein is not simply means or form used by the writer to convey the content of the story. Actually, this syntactic warp and woof of the story, packed with various syntactic figures, not only works together with the story content and tells one part of it but often speaks louder than words, forming unique narrative devices.
The efficient, selective, and economical sorbents for the removal of Sr radionuclides are largely needed for the decontamination of effluents with high salinity. In this study, the removal of Sr was investigated using the zeolite produced from the Bayer process liquids. Based on the XRD, SEM/EDS analysis, the product was pure and highly crystalline zeolite 4A (Z4A). Removal of Sr was fast (5 min for 100% removal at 8.80 mg/L), with high maximum sorption capacity (252.5 mg/L), and independent on the initial pH in the range 3.5–9.0. Specific sorption of Sr by protonated groups on the Z4A surface was operating in addition to ion-exchange with Na ions. The selectivity of Z4A decreased in the order Sr > Ca > K > Mg > Na. 84% of Sr was separated from seawater within 5 min, at the Z4A dose of 5 g/L, while efficiency increased to 99% using the dose of 20 g/L. Desorption of radioisotope 89 Sr from seawater/Z4A solid residue was very low in deionized water (0.1–0.2%) and groundwater (0.7%) during 60 days of leaching. Z4A is a cost-effective, selective, and high-capacity medium for Sr removal, which provides high stability of retained radionuclides.
The efficient, selective, and economical sorbents for the removal of Sr radionuclides are largely needed for the decontamination of effluents with high salinity. In this study, the removal of Sr was investigated using the zeolite produced from the Bayer process liquids. Based on the XRD, SEM/EDS analysis, the product was pure and highly crystalline zeolite 4A (Z4A). Removal of Sr was fast (5 min for 100% removal at 8.80 mg/L), with high maximum sorption capacity (252.5 mg/L), and independent on the initial pH in the range 3.5–9.0. Specific sorption of Sr by protonated groups on the Z4A surface was operating in addition to ion-exchange with Na ions. The selectivity of Z4A decreased in the order Sr > Ca > K > Mg > Na. 84% of Sr was separated from seawater within 5 min, at the Z4A dose of 5 g/L, while efficiency increased to 99% using the dose of 20 g/L. Desorption of radioisotope 89Sr from seawater/Z4A solid residue was very low in deionized water (0.1–0.2%) and groundwater (0.7%) during 60 days of leaching. Z4A is a cost-effective, selective, and high-capacity medium for Sr removal, which provides high stability of retained radionuclides.
ABSTRACT Flaviviruses such as the dengue (DENV) and the Zika virus (ZIKV) are important human pathogens causing around 100 million symptomatic infections each year. During infection, small subgenomic flavivirus RNAs (sfRNAs) are formed inside the infected host cell as a result of incomplete degradation of the viral RNA genome by cellular exoribonuclease XRN1. Although the full extent of sfRNA functions is to be revealed, these non-coding RNAs are key virulence factors and their detrimental effects on multiple cellular processes seem to consistently involve molecular interactions with RNA-binding proteins (RBPs). Discovery of such sfRNA-binding host-factors has followed established biochemical pull-down approaches skewed towards highly abundant proteins hampering proteome-wide coverage. Yeast three-hybrid (Y3H) systems represent an attractive alternative approach. To facilitate proteome-wide screens for RBP, we revisited and improved existing RNA-Y3H methodology by (1) implementing full-length ORF libraries in combination with (2) efficient yeast mating to increase screening depth and sensitivity, and (3) stringent negative controls to eliminate over-representation of non-specific RNA-binders. These improvements were validated employing the well-characterized interaction between DDX6 (DEAD-box helicase 6) and sfRNA of DENV as paradigm. Our advanced Y3H system was used to screen for human proteins binding to DENV and ZIKV sfRNA, resulting in a list of 69 putative sfRNA-binders, including several previously reported as well as numerous novel RBP host factors. Our methodology requiring no sophisticated infrastructure or analytic pipeline may be employed for the discovery of meaningful RNA–protein interactions at large scale in other fields.
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