Background: The new coronavirus SARS-CoV-2 caused a pandemic that threatened all aspects of life and health while worsening the socio-economic situation of the entire population. COVID-19 affects all organs and organ systems. The symptoms of the affected organs can last for a long time after the acute infection. About 1/3 of patients develop neuropsychiatric signs in the clinical course of the disease. The most common symptoms are mental fog, headache, cognitive changes, behavior changes, muscle weakness, anosmia and ageusia. These symptoms may develop due to a direct effect of the virus on the neurons or hyper reactive immune response. Objective: The aim of this article is to describe 2 young adults who developed neuropsychiatric symptoms in the course of Long COVID-19 syndrome. Ischemic vasculitis was proved using CT imaging. Case report: We collected data of two younger females who had previously recovered from the acute form of COVID-19 without respiratory complications. They developed in the next 1-2 months a clinical picture of a brain disorder. In both cases, CT and angiography scans of the brain showed signs of ischemic vasculitis. Neurological therapy has led to an improvement of the neuropsychiatric symptoms. Conclusion: Neuropsychiatric disorders in Long Covid syndrome are common and diverse. Two cases of young adults who developed signs of neurological disorder in the post COVID-19 period were presented, and CT scans of the brain showed signs of ischemic vasculitis.

The increasing use of video streaming services that followed the Covid-19 pandemic has more than ever driven a rising interest among various stakeholders in service provisioning chain to understand factors influencing quality of experience (QoE). Many research activities have so far addressed different influence factors in order to understand and improve QoE when using video streaming service. However, we have recognized the requirement to address QoE as multidimensional concept, and show the relationship between QoE, perceptual dimensions, and influence factors. In this paper, we provide the multidimensional modelling and analysis of QoE for video streaming. Result analysis has shown that QoE for video streaming can be modelled by using perception of quality of video and perception of ease of use of application as predictors. The analysis of influence of individual system (i.e., resolution, coding tree unit (CTU), and constant rate factor (CRF)), context (i.e., location, lighting, and video type), and human (i.e., gender, education level, and prior experience) factors and their interactions on QoE perceptual dimensions (i.e., perception of quality and perception of ease of use) show statistically significant impacts, which means that alternations of these factors can enhance perceptual dimensions and consequently QoE for video streaming which is a final goal.

Abstract In the process of designing a system, it is necessary to identify potential threats to that system and to include appropriate countermeasures. The process that helps in finding problems in the initial phase of the system design is the threat modeling. Creating a threat model consists of several steps and there are many tools that can help in automating the procedure. This article deals with the threat analysis for an Ambient Assisted Living (AAL) system based on Wireless Sensor Network (WSN), whose main function is to provide information for carers in order to provide the best possible help to the elderly and disabled. We have identified and analysed 99 potential threats to the considered system, where Denial of Service (DoS) resulted in being the most represented class of threats. After conducting the threat assessment, the obtained results showed that the majority of threats are high-risk and justified the use of threat modeling in the design phase, since they can be utilized in further system development stages.

O amendoim é uma cultura agrícola amplamente conhecida no Brasil. O consumo in natura é o principal meio de aproveitamento da produção. Originário da América do Sul é uma das oleaginosas mais cultivadas em todo mundo, em razão da grande variabilidade nas formas de consumo, sabor e adaptabilidade de produção em áreas tropicais e subtropicais. O objetivo do presente trabalho foi avaliar o desempenho das características agronômicas de crescimento e produtividade de cinco acessos de amendoim sob adubação orgânica. O trabalho foi conduzido no câmpus das Auroras da Unilab, entre abril e julho de 2018. Foi utilizado um delineamento estatístico de blocos casualizados (DBC) com cinco tratamentos e seis repetições. Foram analisadas as características agronômicas: Dias de Emergência (DE), Altura das Plântulas (AP), Números de Ramos, Número de Vagens por Planta (NVP), Número de grãos por Planta (NGP), Peso de massa fresca (PMF), Peso de Massa Seca (PMS) e Peso de 100 grãos (P100G). Os dados foram submetidos à análise de variância em delineamentos de blocos casualizados com três repetições. Os quadrados médios foram comparados pelo teste F e as médias pelo teste de Tukey a 5%. Os acessos Unilab 130 e Unilab 138 destacaram-se em peso e produção de vagens sendo bons genótipos de porte rasteiro. Unilab 107 e 124 situaram-se como intermediários aos demais acessos em relação à produção e podem ser considerados para produção desde que atendidas suas exigências de cultivo. Unilab 130 apresenta-se como um bom genótipo a ser utilizado como genitor em programas de melhoramento.

Negativni efekti izvođenja radova u sektoru šumarstva sa aspekta zdravlja i sigurnosti radnika posebno su izraženi u okviru tehnološkog procesa iskorištavanja šuma. Sječa stabala i izrada šumskih drvnih sortimenata u Bosni i Hercegovinin obavlja se motornim pilama, a privlačenje drveta skiderima u najvećem broju slučajeva. Cilj istraživanja prikazanog u ovom radu je utvrđivanje opterećenja radnika u fazi sječe i izrade šumskih drvnih sortimenata iz razloga djelimične mehanizacije radova, tj. upotebe motor-manuelnog sredstva rada. Težina rada može se procijeniti na osnovu pulsa radnika, poređenjem pulsa mjerenog tokom odmora i rada, što je zbog praktičnosti veoma pogodan metod za istraživanja u oblasti šumarstva. Mjerenje pulsa sjekača obavljeno je uz upotrebu Garmin Forerunner 35 pametnog sata za trčanje (Garmin Ltd., United States) sa kontinuiranim mjerenjem i čuvanjem podataka. Rad sjekača sniman je akcionom kamerom tokom cijelog radnog dana. Istraživanje je provedeno u mješovitim raznodobnim šumama bukve i jele sa smrčom na području kojim gazduju KJP „Sarajevo šume“  i JP „Šumsko - privredno društvo Zeničko - dobojskog kantona“  d.o.o. Zavidovići. Prosječan puls tokom rada uključujući produktivno vrijeme i prekide rada iznosi 117 o/min (otkucaja u minuti) za radnika A, odnosno 113 o/min za radnika B. Rezultati Kruskal-Wallis testa su pokazali postojanje statistički značajnih razlika u vrijednostima prosječnog pulsa u zavisnosti od elementa studija rada (radne operacije i prekidi rada). Najmanje vrijednosti pulsa evidentirane su tokom pripremno-završnog vremena za oba radnika, a najveće vrijednosti tokom hoda do radilišta za radnika A, odnosno rješavanja ustave za radnika B. Prosječni puls tokom rada (%HRR) za radnika A iznosi 47.15%, odnosno 50.00% za radnika B. Rezultati istraživanja su pokazali da opterećenje sjekača prelazi dozvoljenu vrijednost od 40% što odgovara teškom radu i može imati negativni uticaj na zdravlje radnika. Uzimajući u obzir da su utvrđene nešto veće vrijednosti prosječnog pulsa tokom rada (%HRR) u odnosu na rezultate drugih istraživanja neophodno je razmotriti mjere za njegovo smanjene a koje bi podrazumijevale obuku radnika, promjene u organizaciji rada i kontinuiranu procjenu radne sposobnosti radnika.

The paper investigates the phenomenon of soil erosion on skid roads/trails. The aim was to discover how and to what extent different longitudinal slopes can influence the occurrence of erosion processes. For this purpose, a total of nine experimental plots were set up at three different sites. The length of the plots was 110 m, and at all localities, the research was carried out on different longitudinal slopes (up to 10%, 10 - 20% and over 20%) over the observed period of approximately two and a half years. The research focused on determining the volume of material removed and the dynamics of the development of erosion processes observed in phases (shifts) between recordings. Forests are the most effective natural factor in protecting land from erosion, and if they are managed on the principles of sustainable management, the so-called "normal" erosion usually occurs. However, as it is necessary to build a relatively dense network of skid roads/trails for different phases of management, it makes them susceptible to more intensive erosion processes. If we take into account that they were built with very low criteria (technical elements) and without the existence of facilities that would ensure the drainage of surface and rainwater, and can be built with a large longitudinal slope, it creates optimal preconditions for the development of intensive erosion process. The conducted research has obtained results that clearly show that erosion processes occur frequently, of varying intensity depending on the factors that prevail for a given locality. The value of the volume of the removed material ranges from 1.278 m3, ie 0.0116 m3/m to 5.313 m3, or 0.0483 m3/m. The obtained minimum value of the volume of the removed material can be related to the strong water permeability of the parent substrate (limestone), which affects the reduction of surface runoff, as well as shallow soils that are formed on it. When it comes to the maximum value of the volume of removed material, which is 5.333 m3 or 0.0483 m3/m, it can be related to the continuous occurrence of surface runoff that causes surface sapping and removal of material from the skid roads/trails. The performed statistical analyzes (through a linear model) indicate different correlations of investigated influencing factors (volume of transported material and length of skid roads/trails on different longitudinal slopes). The obtained correlation values range from r = 0,29 (weak correlation) to r = 0,79 (very strong correlation).

Psoriasis is an autoimmune and inflammatory skin disease. Psoriatic patients express higher levels of plasma homocysteine (Hcy) concentration and pro-inflammatory mediators than healthy people; this is frequently associated with vitamin D deficiency. The aim of this clinical study was to investigate the effects of high doses of vitamin D supplementation on the parameters of Hcy metabolism and cytokines in sera of psoriatic patients. This prospective study was conducted on 40 psoriatic patients who had the vitamin D deficiency. All patients received vitamin D 5000 IU/day for three months. Clinical and biochemical measurements were taken at baseline and at follow up (3 months). The results showed that the severity of clinical features, measured by the psoriasis area severity index (PASI) score, were considerably improved in patients after vitamin D supplementation. After vitamin D supplementation, most of the patients (n = 25 or 62.5%) had mild clinical form (p < 0.001). After twelve weeks of intervention period, there were significant increases in vitamin D and B12 serum levels in comparison to the levels that had been measured at the beginning of the study (56.77 ± 14.66 nmol/L and 301.08 ± 95.02 pg/mL vs. 103.85 ± 32.20 nmol/L and 362.81 ± 118.56 pg/mL, respectively; p < 0.001). Moreover, serum levels of Hcy and folate were significantly lower at the end of the study in comparison with the initial levels (12.45 ± 1.92 µmol/L and 8.01 ± 3.88 mg/mL vs. 10.38 ± 1.66 µmol/L and 6.27 ± 2.60 mg/mL, respectively). High doses of vitamin D supplementation led to a significant decrease in pro-inflammatory cytokines (IFN-ɤ, TNF-α, IL-1β, IL-6, IL-8, and IL-17) and high-sensitivity C-reactive protein (hsCRP), whereas the production of anti-inflammatory cytokines (IL-10, IL-5) was up-regulated. In conclusion, supplementation with high doses of vitamin D could be one of the possible preventive and therapeutic measures to reduce systemic inflammation in psoriatic patients.

Abstract Interspecific hybridization in the Cyprinidae family has been recorded worldwide, with Abramis brama (bream) and Rutilus rutilus (roach) as one of the often-reported hybridizing pairs. The only account of such an event in Bosnia and Herzegovina has been in Modrac Reservoir. Using morphological and molecular markers, the presence of hybrids was surveyed, the hybridization direction was determined and the hybrid group structure in this ecosystem was evaluated. Our findings confirmed unhindered natural hybridization between roach and bream in Modrac Reservoir. Over 50% of the hybrid specimens were classified as F2 hybrids by the NewHybrids software, while the rest were categorized as pure parental form, making it the first such finding in Europe. The analysis of mitochondrial cytochrome b showed that 90% of hybrid individuals were of bream maternal origin. The hybrid group expressed higher mean values of observed heterozygosity and gene diversity than both parental species. Signs of introgressive hybridization between parental species were detected. The hybrid zone of Modrac Reservoir appears to follow the intermediate or “flat” hybrid model based on the balanced distribution of parental and hybrid genotypes. Further investigation is needed to elucidate the factors that enable the survival and mating success of post-F1 individuals.

Background: Bosnia and Herzegovina (B&H) is one of the countries of Southeast Europe with the lack of data about chronic autoimmune thyroid diseases (CAITD) epidemiology. Objective: This research aimed to assess incidence of CAITD in the Tuzla Canton of B&H during a 6-year period (2015–2020). Methods: We retrospectively evaluated 82,000 hospital records of inpatients and outpatients with possible thyroid symptoms residing in Tuzla Canton of B&H (total of 445,028 inhabitants). The study included patients with laboratory and clinical proof of autoimmune thyroid diseases (AITD). Incidence rates were calculated with age standardisation using European standard population. Trends in incidence were evaluated as moving three-year averages. Results: During the observed period, 1875 patients satisfied the diagnostic criteria for CAITD with male to female ratio of 1: 8.01. Median age of all cases was 46 years (interquartile range: 31 to 61) and women and men were on average the same age at the time of diagnosis. The overall standardized incidence was found to be 71.25 per 105 (%95 CI=63.36–79.15). The overall standardized incidence in men was 16.25 per 105 and 123.74 per 105 in women. In the end of the observed period, AITD prevalence was 427.52 per 105 (% 95 CI=408.17-446.87). Conclusion: There was a slight decline of incidence in our region during the observed period. This decrease might be the result of combination of various factors, mainly the Corona epidemics outbreak and emigration. On the basis of the lower incidence rate in the Tuzla Canton, one can assume that iodine prophylaxis carried out in order to eradicate goitre had satisfied expectations because there had not been any enormous increase in patients with AITD.

Introduction: The coronavirus disease 2019 (COVID-19) pandemic has put national health systems under extremely large pressure. Health systems throughout the world demonstrated different levels of preparedness for COVID-19 pandemic. Aim: The aim of the study was to investigate the association of resilience with quality of life and self-esteem in healthcare workers of COVID-19 hospital. Methods: We performed a cross-sectional study between November 2020 and February 2021 in COVID-19 hospital at the University Clinical Hospital Mostar. A socio-demographic questionnaire specifically designed for this study, a CD-RISC25 scale for assessing resilience, a WHOQOL-BREF questionnaire for assessing quality of life, and a RSES scale for assessing self-esteem were used for collecting data. Results: A statistically significant higher resilience was in healthcare workers who felt adequately prepared for work in COVID-19 hospital. Resilience, quality of life and self-esteem statistically significantly positively correlated with one another among healthcare workers. A healthcare worker’s resilience level was statistically significantly affected by psychological domain of the quality of life, gender, and adequate preparation. Conclusion: Resilience is positively related to the quality of life and self-esteem in healthcare workers of COVID-19 hospital at the University Clinical Hospital Mostar.

Introduction: Stroke is the second leading underlying cause of death globally and the leading cause of disability in adults. Stroke diagnosis should be performed quickly and efficiently to eliminate other potential causes of neurological deficits and to assess the time since the onset of clinical symptoms. Computed tomography (CT) and magnetic resonance imaging (MRI) are essential methods of detecting and evaluating stroke type and treatmentoptions. Diffusion and perfusion MR imaging is recommended for early stroke diagnosis, as well as for the selection of patients for recanalization therapy, and is considered effective in assessing treatment outcomes. The objectives of this study were to demonstrate the diagnostic value of diffusion and perfusion imaging in the diagnosis of acute ischemic stroke, analyze the role of magnetic resonance imaging in the selection of patients with acute stroke for recanalization therapy, and assess the effect of acute stroke complicity.Material and methods: The research is designed as a systematic review of the primary scientific research literature, which was published in English in relevant scientific databases (PubMed, Google Scholar, Medline) from 2014 to 2021.Results: 14 scientific research papers were singled out and the general characteristics of the study were analyzed (country, authors, year of publication, title of the study, type of study, study objectives, research methods, results and conclusion). A quality assessment of the included studies with cohort design and randomized controlled studies was performed, and most belong to the category of high-quality studies with a smaller number of medium-quality studies. The overall percentage of detected AIS cases in isolated studies using the DWI and/or PWI sequence was 90.8%. At the same time, the outcome of recanalization therapy was assessed using MRI studies (the number of patients who developed adverse events with functional data outcome 30 or 90 days after the procedure was observed). Comparison of MRI and CT imaging protocols provided data on the total percentage of detected acute stroke cases using CT imaging protocols (68.9%) and MRI imaging protocols (88.5%), which is why MRI is considered a superior method.Conclusion: Although CT is a suitable method for visualizing bleeding and also for early differentiation of hemorrhagic from ischemic stroke, if MRI imaging is available, it is recommended to use DWI, PWI, MRA sequences for a more accurate diagnosis of stroke in the acute phase.

Introduction: The knee joint has a unique anatomical structure in the human body. The localization between the two longest bones in the human body – femur, and tibia – makes it prone to injuries, trauma, and other pathologies. Clinical examination of the joint is still the primary method in evaluating the condition of the patient's knee. The study aims to determine the diagnostic accuracy of clinical examination and magnetic resonance (MR) in assessing chondral lesions of knee joint using arthroscopy as a reference standard.Patients and methods: The examination was conducted on 94 patients (58 males and 36 females) with knee injuries. Clinical examination indicated a primary chondral lesion of knee cartilage in eight patients (five men and three women), with an average age of 45.75. Besides the clinical examination, the diagnostics were performed using MR imaging by Siemens of 0.5 Tesla, and arthroscopy was performed using Storz arthroscope.Results: Our research has generated the following values of clinical and MR results for chondral lesions: Sensitivity (Se) = 12.5%, Specificity (Sp): could not be calculated, Positive Predictive Value (PPV) = 100%, Negative Predictive Value (NPV) = 0% and Accuracy (ACC) = 12.5%. The accuracy of clinical and intraoperative results for chondral lesion was: Se =100%, Sp: could not be calculated, PPV = 100%, NPV: could not be calculated, and ACC = 100%. MR imaging and arthroscopy findings of chondral lesion showed: Se = 100%, Sp = 0%, PPV = 12.5%, NPV: could not be calculated and ACC = 12.5%. In comparing the clinical sign and MRand intraoperative result, Positive Predictive Value for patients with chondral lesion was maximal (100%), while comparing MR with the intraoperative result, Positive Predictive Value was 12.5%. In comparison between clinical sign and intraoperative results, the accuracy for patients with chondral lesion was 100%, while comparing the clinical sign with MR result and MR with the intraoperative result, the accuracy was 12.5%.Conclusion: Our examinations have shown that MR examination is not currently as valid for diagnosing injury of chondral cartilage of knee as the medical community or patients have anticipated it.