Radiation-based local-regional therapies for hepatocellular carcinoma (HCC) have gained wide acceptance due to promising rates of tumor response, survival, and safety profiles. After treatment, it is important to assess tumor response to determine further management, patient prognosis, and endpoint outcomes for clinical trials. To standardize imaging interpretation and reporting of HCC response to local-regional treatment, a few imaging-based response assessment systems were developed. Two of them have emerged as the most used: the Liver Imaging Reporting and Data System (LI-RADS) Treatment Response Algorithm (LR-TRA) and the modified Response Evaluation Criteria in Solid Tumors (mRECIST). While these systems have been validated for the assessment of response to ablative locoregional therapies, assessment of response to radiation-based therapies can be challenged by persistent or evolving imaging features and is still an area of active research. Following the advances in technology and a better understanding of tumor biology that allowed for the increased application of radiation-based local-regional therapies for the treatment of HCC, research is still needed to address the limitations of current imaging criteria for assessing tumor response to these novel techniques. In this review, we describe radiation-based liver-directed treatment options, examine imaging criteria for assessing treatment response, discuss practical limitations and gaps in knowledge when applying these response criteria, and address future directions that may help to improve accuracy and outcomes when assessing response to radiation-based HCC treatment.

Food spoilage is phenomenon associated with occurence of the microorganisms in agricultural products. Due to the ability of several microorganisms to colonize plant material, agrochemicals were proposed to suppress bacterial growth. However, overuse of agrochemicals has detrimental impact on environmental quality. Therefore, the objective of this research was to evaluate the potential of aqueous extracts of garlic (Allium sativum L.), wild garlic (Allium ursinum L.), and chives (Allium schoenoprasum L.) to suppress the growth of Enterococcus faecalis and Escherichia coli. The antimicrobial activity of these plant extracts was determined using the disc diffusion method. Mueller-Hinton agar was inoculated with bacterial inoculum; six filter paper disks, impregnated with 15 μl aqueous extract (1, 2 and 4%), were placed on each agar surface. The Petri dishes were incubated at 37 °C for 24 hours. The diameter of the zone of inhibition was measured and expressed in millimeters (mm). Almost all aqueous extracts showed a negligible effect on the growth of E. coli and E. faecalis. Significant suppression of bacterial growth compared with other treatments was observed with the aqueous extract of wild garlic at a concentration of 4%. This research confirms the potential of wild garlic extract in suppression of potential pathogens.

Svrha rada je da pruži pregled poslovnog okruženja u Bosni i Herce­govini i objasni njegov uticaj na priliv stranih direktnih investicija. U radu će se dalje analizirati struktura, iznosi i priliv stranih direktnih investici­ja koje je Bosna i Hercegovina privukla posljednjih godina. Prema podacima iz izvještaja međunarodnih organizacija, a na osnovu veći­ne pokazatelja, Bosna i Hercegovina i dalje zaostaje za susjednim zemljama. Da bi se stimulisao priliv stranih direktnih investicija, potrebno je stvoriti pre­duslove za njihov veći priliv, ali i stvoriti povoljan poslovni ambijent koji će biti atraktivan za strane investitore. Bosna i Hercegovina mora preduzeti niz aktivnosti, kako bi unaprijedila uku­pnu poslovnu klimu. Koje su to postojeće poslovne prepreke koje treba priori­tetno otkloniti, što bi rezultiralo povećanjem stranih direktnih investicija, ta­kođe će biti predmet razmatranja u ovom radu.

The state of the Vatican City and its state-legal system is an interesting and inexhaustible topic for both lawyers and historians, theologians, sociologists, political scientists and other experts who study social phenomena. For a lawyer, the specific legal position of the Vatican and the Holy See, for example in international law and their relationship with other sovereign entities, states and international organizations and other (non-state) entities, is definitely a particularly interesting question. A lot has been written about it. That is why we cannot give the impression that the internal state and legal system of the Vatican has been neglected. For this reason, the author of this paper decided to present one branch of the internal law of the Vatican City State. Criminal law definitely represents an important segment in the legal system of every country. It developed and evolved. The development of criminal law (in the theoretical and practical sense) was accompanied by changes in the penal/criminal legislation. The penal/criminal legislation of this papal "mini-state" is apparently specific. However, the paper before you will not be a discussion about the origin and nature of Vatican penal/criminal law. That will be left for another time. With the Lateran Pact and the creation of the Vatican City-State, positive Italian legislation was taken over. That legislation underwent certain changes by "Vatican law". The latest novelties in the penal/criminal legislation of the Vatican City State are the subject of this work, and the author will try to present them in a concise way and thus try to give his modest development of jurisprudential thought about Vatican (penal/criminal) law.

: The Jonah sarcophagus from Singidunum belongs to a group of Budakalász travertine sarcophagi. These types of sarcophagi were produced in Budakalász quar-ry(ies) and in Aquincum workshops and then exported via the Danube, before being finished in local workshops. This paper uses the Jonah sarcophagus as a case study to examine the integration of traditional tombstones into Early Christian cultural and social contexts.

<p>U ovom radućemo dati procjene sume  ℎ &nbsp;pomoću elementarnih metoda. Navedena suma je poopćavanje problema djelioca i koristi se u procjeni broja podgrupa konačnog indeksa u kristalografskim grupama ([1], [2]).&nbsp;</p>

In this paper, the influence of four factors on the forces during cutting, especially on the friction force was investigated. These factors are water quantity in MQL, speed, depth, and feed rate. In this study, the optimization of those factors to find their optimal combination for obtaining minimal intensity friction force has been looked into. The null hypothesis is that by using the MQL technique, the friction force can be significantly reduced. The experiment was planned using Taguchis L9 design of experiments. The study included performing the machining of the workpiece through different combinations of levels for the spindle speed, feed rate, amount of water, and depth of cut as the main parameters.

Cadastral data can be used for different purposes because it represents important data created in different time periods. Analog cadastral maps like parts of the cadastral register offer graphical data about the locations of the watermills. On the cadastral maps are written a year of the creation of the graphic representation. The year of creation of the plan and the black color of the symbol of the watermill means that it was built before of survey. In the paper, the depictions of watermills in the settlements of Kasapovići and Isakovići in the municipality of Novi Travnik on the cadastral maps of the old and new survey and some historical data were analyzed. Some of the watermills existed on the terrain, but they were not registered in the cadastral register. The locations where watermills exist and where existed were explored. Additional information about watermills collected on the terrain as well as from individual residents of the mentioned settlements was given.

Dudanov park nalazi se sa sjeverne strane naselja Kaštel Kambelovac. Početkom 19. stoljeća park su podigli članovi obitelji Dudan nasuprot obiteljske palače. Arhivska građa o izvornom uređenju perivoja nije pronađena. Sukladno austrijskoj izmjeri iz prve polovice 19. stoljeća, osim agrikulturnih posjeda u neposrednoj blizini palače, obitelj je posjedovala i reprezentativni perivoj karakteristične ortogonalne postave šetnih staza. Uređenje zapuštenog Dudanovog parka (površine 5915 m2) iz 2021. godine bio je veliki iskorak u hortikulturnom uređenju Kaštel Kambelovca. Cilj rada bio je ispitati aspiracije korisnika novoobnovljenog Dudanovog parka. Osim navedenog u radu je izvršena inventarizacija postojeće i obnovljene vegetacije. Rad je proširen analizom dostupne literature, austrijskog katastra i recentnog projekta obnove. Rezultati anketnog ispitivanja su pokazali da je posljednja rekonstrukcija parka ispunila cilj - park je postao često korišteno javno mjesto građana Kaštel Kambelovca i drugih posjetitelja. Usporedbom stanja na terenu i projektne dokumentacije, utvrđeno je da je osnova parka s njegovim sadržajima izvedena prema projektnoj dokumentaciji. Vizualnim pregledom je ustanovljeno da je park vrlo dobro održavan. Taksonomskom analizom obuhvaćeno je 45 svojti gdje dominiraju kritosjemenjače s podjednakom zastupljenošću grmolikih formi i stabala.

Šuma ima važnu ulogu u regulisanju vodnog režima, odnosno prevenciji pojave poplava i bujičnih tokova, što zavisi od vrste drveća koje sačinjavaju sastojinu, stepena sklopa, starosti i strukture sastojine. U ovom radu istraživan je uticaj strukturne izgrađenosti sastojine na vodni režim na primjeru šumske kulture bijelog bora (Pinus sylvestris L.) na krečnjacima u jugozapadnoj Bosni i Hercegovini. U šumskoj kulturi bijelog bora postavljena je eksperimentalna ploha 50x50 metara na kojoj je izvršen potpuni premjer svih taksacijskih elemenata. Pored toga u različitim uvjetima stepena sklopa postavljeni su kišomjeri  pomoću kojih je utvrđivana količina oborina koja dospije do površine šumskog tla. Kišomjeri su postavljeni i na otvorenoj površini u neposrednoj blizini šumske kulture. Istraživanja su pokazala da se sa povećanjem broja stabala na jedinici površine i veće sklopljenosti sastojine povećava zadržavanje oborinske vode u krošnjama stabala i do 30%. U sastojini bijelog bora je utvrđeno 720 stabala po hektaru dok bi za optimalnu intercepciju taj broj trebao biti oko 1.400. Međutim, povećanje broja stabala unutar sastojine se može negativno odraziti na stabilnost sastojine. Kod većeg broja stabala unutar sastojine konkurencija je veća, stabla se suše, vitkost stabala je veća i dolazi do preloma ili izvala stabala. Četrdestogodišnja sastojina bijelog bora je na površini tla formirala šumsku stelju koja ima preko 4 puta veću apsolutnu suhu masu od mase suhe materije pokrova na otvorenoj površini. Istraživanja su pokazala da u skopljenoj sastojini bijelog bora na tlo dospije manja količina oborinske vode, ali da šumska tla imaju bolju sposobnost infiltracije, zadržavanja i ravnomjernog rasporeda vode kroz duži vremenski period. Uzgojnim zahvatima u sastojini može se i sa manjim brojem stabala na jedinici površine postići isti efekat intercepcije ukoliko se potiče bolji razvoj krošnji stabala.

Ozimica, Eranthis hyemalis (L.) Salisb. (Ranunculaceae), je rana proljetnica koja naseljava vlažna staništa umjerenokontinentalne Evrope. Smatra se rijetkom u Sloveniji i Hrvatskoj, dok u drugim zemljama regiona ima statuskritično ugrožene vrste. Ciljevi rada su: 1. revidiranje distribucijske mape za ozimicu u Bosni i Hercegovini(BiH), 2. opis novih nalazišta vrste. Revidirana mapa je urađena u QGIS ver. 3.4. na osnovu 19 georeferenciranihpodataka iz literature te podataka o novim i potvrđenim nalazištima u BiH. Primjerci sa novih nalazišta suherbarizirani i deponovani u Herbarijumu Zemaljskog muzeja u Sarajevu (SARA). Staništa na novim lokalitetimasu analizirana metodom Ciriško-monpelješke škole. Distribucijska mapa ozimice implicira zastupljenostvrste isključivo u crnomorskom slivu, u dolinama Bosne i Vrbasa sa novim lokalitetima u Brezi i Donjoj Gračanici.Na novim nalazištima su konstatovane vrste koje indiciraju nitrifikaciju i/ili šumski fitoklimat. Zbog specifičnefenologije, ozimica je dug period bila zanemarena od strane botaničara u BiH te je početkom 90-ih čak proglašena nestalom u divljini. Novi lokaliteti i potvrda za ranija nalazišta impliciraju potrebu za sistematskim istraživanjima u slivovima Vrbasa i Bosne, kako bi se utvrdilo tačno područje distribucije ozimice u BiH te na taj način dao doprinos u procjeni njenog konzervacijskog statusa na nacionalnom nivou. 

Pepper is one of the most famous and widespread spices in the world. This commercial plant belongs to the Piperaceae family. Depending on the treatment to which the pepper fruit is exposed, we distinguish between black, white and green pepper. In this research, methanolic extracts of different types of pepper (Piper nigrum) and pink pepper (Schinus terebinthifolius Raddi) were prepared. Maceration and ultrasonic extraction were used to extract bioactive components from pepper samples. The reduction potential of the extracts was tested using the FRAP method. The efficiency of free radical inhibition was determined by the DPPH method. Pink pepper extract showed the highest antioxidant activity in in vitro conditions. High antioxidant activity was also recorded in green pepper extracts. In general, the extracts showed high potency in neutralizing free radicals.

Water hardness and deposition of incrustation is a problem in households and industry. In this regard, several technologies have been developed with the purpose of water softening and preventing the deposition of incrustation. The ion exchange method is the most commonly used method and is considered a conventional method. However, due to the shortcomings of this method, there is a need to develop adequate alternative methods. The potential of the method using biosorbents such as moss Leucobryum glaucum and Spaghnum peat moss for the purpose of removing water hardness has recently become the subject of intensive research with growing interest. In this study, the method using Leucobryum glaucum as a biosorbent was tested and a comparison was made with the conventional method and previously conducted studies that used other biosorbents.