: Antigenotoxic and Antioxidative activites of Curcumin Modern biomedical science has proven beneficial effects of curcumin as potential therapeutic candidate for various conditions due to its pleiotropic and pharmacological properties. The aim of the present study was to investigate antigenotoxic effects of curcumin against cisplatin induced genotoxicity as well as its antioxidative effects. In vitro cytokinesis block micronuclei assay in human lymphocytes was used for evaluation of antigenotoxic properties of curcumin. Evaluation of antioxidative properties of curcumin was determined with 2,2-Diphenyl-1-picrylhydrazyl free radical scavenging assay. Results demonstrated significant antigenotoxic and antioxidative properties of curcumin, dependent upon the tested concentrations. Consideration should be given to performing a study with broad dose interval of tested substances. Findings from the present study emphasized application of curcumin as potential antigenotoxic and antioxidative supplementary agent.

The financial reports, as the final product of the accounting information system, need to be accurate in order to maintain the main purpose of financial reporting. Applied methods and techniques of recognition and measurement of financial positions should be in the purpose of realistic and transparent presentation of the financial performances of the entity. However, creative accounting techniques are often used in the process of preparing and presenting financial statements in order to manage earnings and manipulate financial values. Manipulation of financial statements seems to be a generally present phenomenon, and the paper aims to identify the criteria used by members of the accounting profession in the Federation of Bosnia and Hercegovina (FBiH) to distinguish earnings management techniques from fraudulent financial reporting. The research reflects the perception of accountants and auditors in the FBiH regarding the possibility of recognizing suspicious accounting practices in business entities. The research is based on distinctive criteria used in developed economies of the world: measurement subjectivity, the materiality of financial item and compliance of financial reporting with generally accepted accounting principles, but identifies specific distinctive measures used by respondents, too. The results of the research reveal that the accounting professionals in the FBiH rely on distinctive criteria: materiality and compliance of reporting with International Financial Reporting Standards, including two additional measures: compliance of financial reporting with generally accepted practices and confidence of financial information. Respondents did not recognize subjectivity in assessment as a relevant measure of the distinction between earnings management and fraudulent financial reporting.

Background: Retained placenta is one of the major causes of primary and secondary post-partum hemorrhage (PPH) and active management of the third stage of labor reduces the risk of PPH. Objective: The aim of this paper was to compare the efficacy of intra-umbilical vein injection of carboprost versus oxytocin by time and success rates of total expulsion of the placenta. Methods: This prospective clinical study with quasi-experimental design 2x2x2(risk factors by medication by doses) was conducted at Clinic of Obstetrics and Gynecology, Clinical Center of University of Sarajevo in two-year period. Patients were randomized in 4 groups and 8 subgroupsby different medication doses and risk factors. The main outcome variable was expulsion of retained placenta and second outcome variables were: duration of time from intra-umbilical vein administration of drug to expulsion of retained placenta, the number of cases who required blood transfusion and antibiotics, postpartum hemoglobin after 24h. Statistical significance was accepted for p-values < 0.05. Results: The group B2 (UVI oxytocin 20 IU in 20 mL saline, surgical risk factors) and the group D2 (UVI oxytocin 20 IU in 20 mL saline, non-surgical risk factors) had shorter expulsion time (minutes) (Me=5; IQR=4 to 5; Me=5; IQR=4.3 to 6, respectively) compared with other groups (p<0.001). The success rates of total expulsion of the placenta by groups (A,B,C and D) were not statistically significant (70% vs. 82% vs. 72% vs. 78%, respectively; p=0.483). Post-intervention hemoglobin concentrations was statistically significantly greater in the group B(117.3±1.3) vs. the group A (112.1±1.3), (p =0.028). Conclusion: The time for placental expulsion was significantly shorter and postpartum hemoglobin was significantly higher in the intra-umbilical oxytocin groups than in the carboprost groups.

Organizational configuration affects a number of management components, both hard and soft. Hard components include: organizational structure, strategy and control, and soft components are: organizational culture, organizational learning, leadership, motivation, organization power, organizational change, rewarding employees, evaluating performance and connection between individual and organization. Therefore, it can be said that organizational configuration affects organizational culture. The organizational configuration creates a framework in which a specific type of organizational culture is applied. For an organization to be successful in achieving its goals, there needs to be a high degree of agreement between the chosen model of organizational configuration and the type of organizational culture. Therefore, each model of organizational configuration corresponds with a precisely defined type of organizational culture, because only in that way organization will avoid problems in its functioning. This paper is an exploratory type, which means that it will create assumptions about the degree of agreement between specific models of organizational configurations and certain types of organizational cultures. In this paper, based on theoretical implications, assumptions are created about the degree of agreement of Mintzberg's models of organizational configurations, which are re cognized in the literature as Mintzberg's basic types of configurations and typologies of organizational cultures according to Cameron and Quinn, better known as the competing value model. Situational elements that form models of organizational configurations according to Mintzberg and the dimensions on the basis of which are performed the typology of organizational cultures according to Cameron and Quinn are taken into account.

The paper investigates the influence of organizational culture on the leadership style in the company. Every company needs managers who will develop a certain leadership style in order to meet the preconditions for effective actions that will lead to the achievement of the company's goals. Organizational culture in accordance with established norms and rules determines how to understand and accept specific employee behavior, and which leadership style is fitting for managing employees by managers of company leaders. The paper uses a situational approach to leadership according to which the typology of leadership styles is based on two key criteria: concern for people and concern for performance. The classification of organizational culture according to the Edwards and Kleiner typology is based on four types of organizational culture: indifferent culture, caring culture, strict culture and integrative culture. Based on the agreement of the criteria for differentiating the types of organizational cultures and leadership styles, hypotheses about cause-and-effect relations between them are set in the paper.

This work sets out the methodology and presents the calculation results of the amount of carbon dioxide emitted into the atmosphere of the BelAz dump truck at the Open Pit "Turija" BCM Banovići d.d., based on the fuel consumption monitoring data. Properly determined fuel consumption enables the calculation of the amount of carbon dioxide emitted and preventive measures, as well as the choice of its reduction strategy. Data collection took six months, then the data were analyzed, and thus the results were given for all dump trucks by months.

Certain research on the development of motor skills of children with hearing impairment shows that their abilities are not age-appropriate, although they have the same basis for development as hearing children. Education of children with hearing impairments is predominantly focused on hearing and speech rehabilitation, while activities related to music and sports are mostly neglected. The aim of this study was to examine the effects of musical-rhythmic stimulation on the development of selected motor skills of children with hearing impairment aged six to fifteen. For this purpose, a special music and dance program of workshops for 26 children with hearing impairments (12 boys and 14 girls) was created for the period of four and a half months. At the beginning of the program implementation, the initial measurement of body coordination and speed of movement was performed, and the final measurement through five standardized tests at the end. The paired samples t-test was used to analyze the effects of applied musical-rhythmic and dance stimulations. The results of the research indicated certain statistically significant differences in the ability to coordinate the body and speed of movement, i.e. that the program of music and dance workshops has a positive effect on the development of selected motor skills in children with hearing impairment.

Određena istraživanja o razvoju motoričkih sposobnosti djece s oštećenjem sluha pokazuju da njihove sposobnosti nisu u skladu s dobi iako imaju iste osnove za razvoj kao i čujuća djeca. Edukacija djece s oštećenjem sluha dominantno je usmjerena na rehabilitaciju sluha i govora, a aktivnosti vezane za glazbu i sport uglavnom su zanemarene. Cilj ovog istraživanja bio je ispitati učinke glazbeno-ritmičkih stimulacija na razvoj odabranih motoričkih sposobnosti djece s oštećenjem sluha u dobi od šest do petnaest godina. Zbog toga je kreiran poseban glazbeno-plesni program radionica za 26 djece s oštećenjem sluha (12 dječaka i 14 djevojčica) u trajanju od četiri i pol mjeseca. Na početku realizacije programa provedeno je inicijalno mjerenje koordinacije tijela i brzine pokreta te po završetku finalno mjerenje kroz pet standardiziranih testova. Za analizu efekata primijenjenih glazbeno-ritmičkih i plesnih stimulacija korišten je t-test za završne uzorke (paired samples test). Rezultati su istraživanja ukazali na određene statistički značajne razlike u sposobnostima koordinacije tijela i brzine pokreta, odnosno da program glazbeno-plesnih radionica ima pozitivan učinak na razvoj odabranih motoričkih sposobnosti kod djece s oštećenjem sluha.