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S. Šegalo, Arzija Pašalić, Amra Mačak-Hadžiomerović, Daniel Maestro, Muris Pecar, B. Katana

Background: Musculoskeletal disorders (MSDs) are a wide group of diseases that severely affect work productivity and quality of life. Objective: The aim of this study was to examine the differences in the prevalence of MSDs among laboratory professionals (LPs) and to assess their association with individual, psychosocial, and occupational risk factors. Methods: In a multicenter, cross-sectional study, a questionnaire was distributed online through professional association networks. Participants were divided into two groups based on their territorial affiliation - European Union (EU) and non-EU member states. Descriptive and inferential statistics were included in the analysis, and statistical significance was set at ≤0.05. Results: A total of 640 LPs from 20 European countries participated in the study, predominantly females (78.4%), with university degree (59.4%) and a mean age of 41.2 ± 10.1 years. Statistically significant differences between groups were confirmed for several variables studied: neck flexion > 15° (p = 0.008), hands at chest level (p = 0.000), prolonged screen time, and sitting (p = 0.000). One-third of participants reported wrist (35.6%), shoulder (32.7%), and elbow (31.6%) pain, while low back pain was more common (48.9%). A statistically significant association was confirmed between the incidence of MSDs and stress at work, repetitive motions, and prolonged standing (p = 0.000). Several variables showed significant correlations with MSDs in different body parts (p <0.05). Conclusion: Our results show a higher prevalence of MSDs in LPs and we recommend urgent development of targeted prevention programs and additional measures to modify the work environment and organizational activities.

E. Selimović, Elmedin Bajrić

Background/Aim: Surgical removal of impacted third molars is associated with possible complications that are primarily comprehended as expected. Increase in incidence and severity of complications is directly related to the depth of impaction, and to the age of the patient as well. The aim of this research was to investigate the possible influence of the treatment duration relating to age and gender of the patients, the occurrence of pain, and the existence of previous anxiety experience connected with surgical wisdom tooth removal. Material and Methods. The study included adults of both gender indicated for surgical removal of impacted third molars. The existence of previous wisdom tooth removal experience was determined during the first examination, and the subjects' anxiety and pain levels were determined pre-, and postoperatively. Results: There were no differences concerning the place of treatment (dental office/operating room) and the duration of surgery. Younger participants showed the lowest levels of preoperative anxiety and the highest levels of postoperative anxiety, and frequently reported postoperative pain. Female participants showed higher levels of preoperative and postoperative anxiety, and also frequently reported postoperative pain. Conclusions: Anxiety and pain scores were lower when there was a previous experience with removal of impacted wisdom teeth.

E. Selimović, Elmedin Bajrić

Background: Dental fear and anxiety (DFA) is ubiquitous among the adult population. The anxiety component of DFA is more strongly expressed in adults, and includes a physiological and psychological component, and is more often analyzed in research. Oral-surgical interventions represent a significant source of stress for the appearance of anxiety in subjects. The research aim was to analyze the presence of anxiety with the use of the revised Corah Dental Anxiety Scale (DASR) and the Spielberger State-Trait Anxiety Inventory (STAI) in adult patients during the treatment of extraction of impacted third permanent molars by oral surgery. Material and Methods: The study included adult patients of both sexes, who were previously scheduled for oral-surgical removal of third permanent molars. Anxiety levels were assessed preoperatively and postoperatively as follows: 1st measurement (day of examination)-DASR, and STAI (X1 and X2); 2nd measurement (immediately before the intervention)-STAI (X1 and X2); 3rd measurement (day after the intervention)-STAI (X1 and X2). Results: Preoperatively, the presence of high levels of general anxiety, situational anxiety, and dental anxiety was determined. The levels were decreased before the planned surgery and were significantly reduced in the postoperative period. The STAI scale could be used to assess the presence of situational anxiety in the dental office on an equal footing with other known measuring instruments (e.g. DASR). Conclusions: Adequate therapy should be considered to prevent preoperative anxiety, which would increase the satisfaction of patients and therapists while reducing complications related to this type of intervention.

A. Zukanović, Elmedin Bajrić, N. Marković, Damir Duratbegović, Elma Katana, Emina Cengic, Senka Serhatlić, Hasan Pejak

Background/Aim: Deep carious lesions on primary teeth usually have been causing infectious dental pulp changes. If indicated, traditional endodontic root canal treatment for these kinds of pulpal infections in primary teeth usually should involve the performing of pulpectomy methods, but often with questionable prognosis. The lesion sterilization and tissue repair (LSTR) approach is one of the good endodontic therapeutic alternatives for affected primary teeth with a poor prognosis, which could otherwise be condemned to premature extraction. Aim was to evaluate the medium-term clinical success in everyday practice of the LSTR method applied in affected primary teeth with irreversible pulpal tissue infections by observation of reduction/absence of their clinical symptoms. Material and methods: The study sample included child patients who had one or more of their affected primary molars with irreversible pulpal tissue changes of poor prognosis treated with the LSTR method. For each patient whose primary molar tooth was endodontically treated with the LSTR method a clinical evaluation of treated tooth was performed at intervals of 1 and 12 months afterwards. Results: Study sample was consisted of 40 child patients aged 4 to 9 years, with 45 primary molars included in total. It was obvious that the symptoms related to affected sample teeth have already been decreased almost immediately after initial action of triple antibiotic paste. Final outcome after 12-months follow-up period was success of applied LSTR method in 43 (95.6%) affected sample teeth in a way that initial clinical symptoms completely decreased and disappeared. Conclusions: LSTR method has been shown as successful pulpotomy technique for noninstrumental endodontic approach in non-vital pulp treatment of primary molar teeth in a 12-months follow-up period.

Elma Katana, Lejla Šačić-Selmanović, N. Marković, Elmedin Bajrić, A. Zukanović, A. Arslanagić-Muratbegović

Background/Aim: The aim of the research was to examine the general attitude, knoweledge and practice of pediatricians about caries in children of preschool age. Material and Methods: The research was conducted from November 2019 to the end of January 2020. The research consisted of a survey of pediatricians. The questionnaire consisted of 4 modules and 37 questions, which related to the attitude, knowledge and practice of pediatricians on the prevention of early childhood caries. Results: The majority of pediatricians (84.9%) stated that they assess the nutrition of their patients, while 32.1% of them always do oral health assessment, and half of them in the second month of the child's life; and 39.6% assess oral health only if there is a problem. The majority of pediatricians (86.8%) recommended the first dental examination, most often in the first year of the child's life (79.5%), and then every 6 months (43.5%). The majority of respondents did not required information about the dental health of their patients' mothers, fluoride toothpastes and topical application of fluoride as well (62.3-75.5%). The majority of pediatricians (79.2%) have never provided or sometimes provided educational material on caries prevention and control to the parents of their patients. The most accurate answers and the highest percentage of correct answers that the pediatricians had were about attitudes (Z=8.98, 66.63%), while the fewest correct answers and the lowest percentage of correct answers regarding the practices on the prevention of early childhood caries (Z=11.91, 58.90%). Conclusions: The research showed that pediatricians have the good attitudes and knowledge, but do not implement prevention of early childhood caries in practice. The basic deficiency of attitude, knowledge and perception of the importance of prevention is a consequence of insufficient education of pediatricians.

Peter Klimek, E. Dervić, Klaus S. Friesenbichler, M. Gerschberger, Liuhuaying Yang

V. Rebić, E. Hadžimuratović, S. Vincevic-Smajlovic, K. Abduzaimović, Selma Kahvić, M. Aljičević, Amela Džubur-Alić, Edna Supur

Introduction: Ascaris lumbricoides is a widely spread helminthic infection, predominantly affecting children, making them the most commonly infected population group. The objective of this study is to assess the prevalence of Ascaris lumbricoides infestation in two municipalities, Tešanj and Maglaj, and to investigate the occurrence of Ascaris lumbricoides infections in the pediatric population, focusing particularly on preschool children. Materials and Methods: The study involved the collection of 1409 fecal samples from the Tešanj and Maglaj areas, gathered over a 6-month period, spanning from September 2018 to February 2019. The processing of these samples was conducted in the Microbiology Laboratory of Tešanj General Hospital. Results: Out of the total 1409 samples, 129 (9.16%) tested positive for Ascaris lumbricoides infestation. In Tešanj, where 1198 samples were collected, 106 (8.85%) tested positive, while in Maglaj, 211 samples were collected, with 23 (10.9%) testing positive. Notably, the majority of positive cases in both Tešanj and Maglaj were preschool-age children, accounting for 88.68% and 86.96%, respectively. The study did not identify any statistically significant correlation between age and gender distribution among those with positive test results in either Tešanj or Maglaj. Conclusion: Based on the study results, which have highlighted the infestation of preschool children with Ascaris lumbricoides in two municipalities in our country, it is imperative to implement preventive measures aimed at reducing the incidence of infection.

Hana Hodžić, Ajdina Župić, Esma Demirović

The main matter of this research is phenomenon of reading, has won totally different sense among the society which is witnessing the biggest achievements in technology. A lot of people used to write about the fact of how much important reading is and how the reading activity influences personality development in total, one of them was Nil Gaiman, which warns about the future of illiterate generations. On the other side position of literate society, the one that fosters active reading is out of the crisis to be unhappy, uneducated, personalities without flat and emphaty which most often give themselves to some vices. In this paper the function of literature has been highlighted that represents people need, that forms him and his views on the world. Value and importance of literature has been explained in details by Bogdan Popovic in his essay "About literature", hundred year ago. There we are ablo to see two different perspectives of literature reading, especially on fiction and here we can realise how ideas even a long years distance have stayed the same. One of the ideas that has been mentioned in this paper is how reading is a key and libraries are gates of future. Role of teachers in the process of learning, development and nurturing the active reading is the key in the process of education. Alongside the family from where everything starts and incentivises, school is also responsible for growing generations of active readers, the ones that will see the future in libraries. At the end of this paper some annual informations about usage od literature for kids and adults are adults, actually the informations of how much people are visiting the state library "Dositej Obradovic" in Novi Pazar are included.

S. Hajrić, A. Serdarević, G. Sulejmanpasić, Dzenita Besirovic, Avdo Kurtović, Nermina Bajramagic, E. Suljić

Background: Multiple sclerosis is a a complex diesase that may be presented by different neurological symptoms causing impairment of physical, psychological and cognitive functions. Objective: The aim of the study was to evaluate the influence of sociodemographic characteristics on cognitive functions in multiple sclerosis patients. Methods: This study included 60 MS patients treated at the Department of Neurology, Clinical Center University of Sarajevo. Inclusion criteria were clinically definite diagnosis of multiple sclerosis, 18 years of age or older and were able to give written informed consent. Cognitive function was evaluated by the Montreal Cognitive Assessment (MoCa) screening test. Mann-Whitney and Kruskal-Wallis test were used for comparisons between sociodemographic characteristics and MoCa test scores. Results: 76.66% were female patients. Average age of patients was 44.5 years. 70% of patients were married. 73,33% of patients had a high school degree, 20% had a college degree while only 6,66% had primary education. 38,33% of patients were employed, 33,33% were unemployed and 28,33% retired. 88.33% of patients had cognitive impairment, 68.33% having mild cognitive impairment. Executive functions (53,66%) and delayed recall (28,33%) were rated the worst. The median value of the Naming and Language MoCa domains of cognition showed statistical significant correlation with level of education (p<0.05; p<0.01).The mean value of the Language variable was statistically significantly lower in respondents aged 35 and over compared to respondents younger than 35 years (p=0,003;p<0,01), Statistically significant correlation was found between the level of education and cognitive status (rho=0,276,p<0,05), while the other variables (gender, age, marital status and employment ) did not show a statistically significant corellation. Conclusion: High perecentage of MS patients has cognitive impairment. Executive functions are rated the worst. Education is the major factor that contribute to better cognitive functioning in MS patients independent of age or employment status. The highest correlation is found between language and naming domains of cognition. Gender did not prove to be predictive factor of cognition in multiple sclerosis patients at any domain.

Although there is considerable evidence suggesting a strong association of glucose, glycated hemoglobin and fatty acid levels with Type 2 diabetes mellitus (T2D), a limited number of studies have examined the association of individual fatty acids with disease progression. Acutely elevated plasma fatty acids stimulate insulin secretion while chronically elevated plasma fatty acids alter and disrupt insulin secretion. Furthermore, free fatty acids (FFA) are known to interfere with normal glucose homeostasis and affect pancreatic β-cell dysfunction. The study included 24 patients with newly diagnosed type 2 diabetes and 27 healthy controls, and analysis of the level of glucose and glycated hemoglobin was done by routine methods. The concentration of individual FFA was determined by gas chromatography with mass spectrometry detection. The results showed statistically significant differences in glucose, HbA1c, lipid profile, palmitic, linolenic, arachidonic, arachidonic, behenic acid as well as in DHA levels in all participants. In healthy subjects, no significant correlation was found between glucose and individual free fatty acids but a negative correlation was observed between DHA and glycated hemoglobin (p<0.05). Newly diagnosed diabetics showed a negative significant association between glucose and lauric acid concentrations, and also the association of glycated hemoglobin with myristic acid levels (p<0.01 and p<0.05, respectively). These data indicate the association of different types of free fatty acids with glucose levels and their control in the serum of healthy and newly diagnosed type 2 diabetics, and therefore indicate the importance of monitoring glucose levels as well as glycated hemoglobin with concentrations of individual free fatty acids in the progression of diabetes.

This study deals with the unfolded quantities based on the time intervals between successive neutron events from the aspect of the power law. Neutrons from spontaneous fission in special nuclear material induce fission in most cases. In this study, it was demonstrated that the inverse value of the number of induced neutrons decreases following a power function with the increasing radius of a plutonium metal sphere. In addition, it was considered an increase in the neutron background level with increasing altitudes. The inverse value of the mean neutron counting rate depending on altitudes can be described with a power function merely for higher elevations. A linear relationship was obtained by plotting the quantities on logarithmic axes against each other indicating generally a power law relationship for both investigated phenomena. The results of this study showed a connection between two seemingly unrelated neutron phenomena through power laws based on the distributions of time intervals between successive neutron counts. The empirical evidence implies that a connection between the observed quantities in a log-log plot is unchanged except for a multiplicative constant.

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