Aim To use the method of meta-analysis to assess the influence of island population isolation on the sub-structuring of the Croatian population, as well as the influence of regional population groups on the sub-structuring of the Southeastern European population with regard to basic population genetic statistical parameters calculated by using STR locus analysis. Methods Bio-statistical analyses were performed for 2877 unrelated participants of both sexes from Southeastern Europe. Nine autosomal STR loci (D3S1358, vWA, FGA, TH01, TPOX, CSF1PO, D5S818, D13S317, and D7S82) were analyzed by using standard F-statistics and population structure analysis (Structure software). Results Genetic differentiation of Croatian subpopulations assessed with the FST method was higher at the level of the Croatian population (0.005) than at the level of Southeastern Europe (0.002). The island of Vis showed the most pronounced separation in the Croatian population, and Albanians from Kosovo in the population of Southeast Europe, followed by Croatia, Bosnia and Herzegovina, and Hungary. Conclusion The higher structure of Croatian subpopulations in relation to Southeastern Europe suggest a certain degree of genetic isolation, most likely due to the influence of endogamy within rural island populations.

Aim To investigate the influence of specific intrapopulation genetic structures on interpopulation relationships. Special focus was the influence of island population isolation on the substructuring of the Croatian population, and the influence of regional population groups on the substructuring of Southeast European populations. Methods Autosomal short tandem repeat (STR) loci were analyzed by using four forensic parameters: matching probability (PM), power of discrimination (PD), power of exclusion (PE), and polymorphic information content (PIC) on a sample of 2877 unrelated participants of both sexes. A sample set comprising 590 participants was analyzed for the first time, and 2287 participants were included from previous studies. The analysis was performed with PowerStats v. 1.2. Results The analysis of forensic parameters for all nine loci in the Croatian subpopulations showed the largest deviations in the populations of the islands of Korčula and Hvar. The smallest deviations were found in the mainland population. As for Southeast European populations, the largest deviations were found in the population of North Macedonia, followed by Romania, Albanians from Kosovo, and Montenegro, while the smallest deviations were found in the population of Hungary. Conclusion The comparison of forensic parameters between different subpopulations of Croatia and Southeast Europe indicates that the isolation of individual Croatian subpopulations and rare alleles in their gene pool affect the values of forensic parameters. Specific features of (sub)populations should be taken into account for appropriate sampling of the total population when creating a DNA database of STR markers.

Abstract Although forensic accounting is a relatively young scientific discipline, it will certainly be one of the most sought after areas in the coming period, and it is important that activities be undertaken for its development and improvement as soon as possible.

Abstract Fraud in accounting, as well as falsification of financial statements, has a long history, and in recent years their scale has been growing and with much more serious consequences. Decisions made by investors and other users of financial statements based on erroneous financial information cause enormous damage to users of financial information, but also to the general public. Many major financial frauds are only detected when companies reach the point of financial collapse, in a situation where it is difficult to do something to repair major damages.

The goal of this research is to evaluate the effects of applied kinesiological activities of different extensions on the transformation of basal-motor abilities of boys. The sample of respondents is represented by boys, students of VII, VIII and IX grades of primary school. „21. March "Matuzići - Doboj South. The total sample consists of a set of 76 respondents classified into three distinct groups. Based on the boys' statements about their participation in everyday physical activities, groups with the numbering were defined through non-athletes: non-athletes-1, recreational athletes-2 and athletes-3. To assess the basic motor skills of the respondents, the variables according to the Eurofit battery test program were used, as follows: Flamingo balance, endurance in the joint, lying-sitting, running 10 × 5m (back and forth), hand tapping, hand dynamometry, flexibility-mobility at the hip joint, jumping away from the spot and running 20m back and forth with progressive acceleration. The results of univariate covariance analysis showed high significance in endurance assessment tests (SHATL 20 and SHATL 10 × 5), followed by static arm strength (MSSIZG), and hand strength (MSSDIN) and torso flexibility (MFLPRK) and balance (MRFLAM). Statistically significant differences in effects did not occur with the three variables, namely hand tapping ( MBFTAR), long jump (MESSDM) or squat-sitting (MRSLSJ). Keywords: Boys, basic motor skills, kinesiological activities, extensibility

Background: Hypertension is the most important risk factor for cardiovascular morbidity and mortality. Blood pressure control rates are as low as 17% to 31% in patients diagnosed with hypertension in high-income countries; control rates are likely poorer in low- to middle- and low-income countries. Blood pressure control rates are as low as 17% to 31% in patients diagnosed with hypertension in high-income countries; control rates are likely poorer in low- to middle- and low- income countries. Overall, 43% to 66% of patients fail to adhere to their prescribed antihypertensive medications, and after 1 year, ≈40% of patients with hypertension may stop their initial drug treatment. Objective: The aim of the study was to evaluate the effects of single pill combination antihypertensive drugs on the adherence to treatment, blood pressure control and cardiovascular events vs. free-combination therapy. Methods: We enrolled 192 adult hypertensive patients not older than 79 years, with untreated or uncontrolled hypertension despite previously receiving free combination antihypertensive therapy, between November 2020 and March 2022. Patients treated with single pill combination (SPC) were compared with an arm of the same size (n = 96) and matched by age and gender who received a standard free combination (FC) antihypertensive therapy. Results: There were significant reductions from baseline to month 6 of follow-up in office SBP in the SPC group vs. reduction in FC group (21.9 vs. 13.1 mmHg; p < 0.0001). There were significant reductions from baseline to month 6 of follow-up in office DBP in the SPC group vs. group with free-combination therapy (13.7 vs. 8.0 mmHg; p < 0.0001). At 6 months, 94 participants (98%) were still prescribed the SPC therapy. At the final 6-month study visit, 84.2% of patients in the SPC therapy group were adherent to the prescribed antihypertensive therapy vs. 52% of patients in the FC group. Target BP values (mean 24h ambulatory systolic/diastolic BP < 130/80 mmHg) were reached by more recipients of SPC than free-combination therapy (78.2% vs. 46.3%, p < 0.05) at month 6 of follow-up. Conclusion: Treatment with single pill combinations (SPC), is the emerging best practice for safe, effective, rapid, and convenient hypertension control. It improves the affordability, adherence and control of arterial hypertension.

Juvenile cystic adenomyoma (JCA) is a rare uterine pathology with <40 cases reported in the current literature since 1996 when Tamura described it. We report a 13-year-old girl with a history of chronic pelvic pain and dysmenorrhea for 12 months. After diagnostic evaluation and identification of the cystic structure ( ∼ 6 cm) within the myometrium, fertility-sparing surgery was successfully performed. Histopathological examination of the uterine cyst was consistent with the diagnosis of JCA. The postoperative course was uneventful, and the patient was disease-free three years after surgery. JCA is a rare condition but should be considered in the differential diagnosis in adolescents with moderate to severe dysmenorrhea. Despite diagnostic advances, the awareness of the disorder remains low. Thus, our case report aims to increase awareness of this rare pathology with unclear etiology.

Due to the lack of channel reciprocity in frequency division duplexity (FDD) massive multiple-input multiple-output (MIMO) systems, it is impossible to infer the downlink channel state information (CSI) directly from its reciprocal uplink CSI. Hence, the estimated downlink CSI needs to be continuously fed back to the base station (BS) from the user equipment (UE), consuming valuable bandwidth resources. This is exacerbated, in massive MIMO, with the increase of the antennas at the BS. This paper propose a fully convolutional neural network (FullyConv) to compress and decompress the downlink CSI. FullyConv will improve the reconstruction accuracy of downlink CSI and reduce the training parameters and computational resources. Besides, we add a quantization module in the encoder and a dequantization module in the decoder of the FullyConv to simulate a real feedback scenario. Experimental results demonstrate that the proposed FullyConv is better than the baseline on reconstruction performance and reduction of the storage and computational overhead. Furthermore, the FullyConv added quantization and dequantization modules is robust to quantization error in real feedback scenarios.