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Background: Patients infected by coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), display various symptoms and severity of the clinical picture. Thus, the therapy and pathophysiology of this disease are a dilemma for health professionals and scientists. Objective: This paper aims to evaluate the effectiveness of therapeutic protocols (the use of anticoagulants) in the treatment of COVID-19 patients of various severity of the clinical picture by monitoring coagulation markers (PT, INR, aPTT and D-dimer), as well as the impact of the type and number of comorbidities patients had on these markers. Methods: A total of 200 patients with a mild (n=76), moderate (n=70) or severe (n=54) clinical picture was included. Coagulation markers [PT (prothrombin time), INR (international normalized ratio), aPTT (activated partial thromboplastin time), D-dimer] were examined on three occasions: twice during hospitalization and once after hospital discharge. Anticoagulants used intrahospital were fraxiparine, rivaroxaban or unfractionated heparin. Posthospital, patients were taking either rivaroxaban or did not use any anticoagulants. For statistical analysis, SPSS 26.0 and Microsoft Excel 2019 were used, with a level of significance of α=0.05. Nonparametric tests (Kruskal-Wallis, Wilcoxon Signed-Rank and Bonferroni) were applied and effect size (ES) was calculated. Results: Three anticoagulants used intrahospital caused a significant decrease in PT, INR and D-dimer and a significant increase in aPTT, especially in patients with a severe clinical picture, but the ES was the biggest with fraxiparine, then rivaroxaban, and lastly unfractionated heparin. Posthospital, rivaroxaban caused a significant decrease in PT, INR and D-dimer and a significant increase in aPTT, especially in patients with a severe clinical picture. Hypertension was the most common comorbidity in all patients, as well as in patients with a severe clinical picture. There was a statistically significant impact of the number of comorbidities patients had on D-dimer, and none on PT, INR and aPTT, but the highest number of comorbidities was in patients with a severe clinical picture. Conclusion: The use of anticoagulants, especially fraxiparine intrahospital and rivaroxaban posthospital, is justified in most COVID-19 cases as there is a significant correlation between this disease’s pathophysiology and the coagulation process. There is also a positive correlation between the severity of the clinical picture and the number of comorbidities patients have.

Andreas Kartakoullis, Nina Slamnik-Kriještorac, Valentin Carlan, Alexandru Vulpe, George Suciu, Marius Iordache, J. Brenes, Giada Landi et al.

In this paper we present VITAL-5G platform, a flexible 5G innovative infrastructure that can host Network Applications (NetApps) to optimize the performance and the efficiency of services in the Transport & Logistics (T&L) sector. It is a complete system that comprises hardware, software

Interaction channels are special opportunities to improve customer satisfaction by offering a consistent problem-solving experience. Contact center employees are the link between the company and the customer. They are responsible for maintaining an appropriate relationship between the company and the customer. So, they are personally responsible for the customer experience. In this paper, we present an objective evaluation method for evaluating customer-agent interaction, i.e., evaluating the effectiveness of the realization of customer requests from calls. The evaluation method is automatic and does not depend on the relationship between the call center manager and the employees. The motivation for evaluating calls stems from the key performance characteristics of a contact center, of which we particularly emphasize service time, first call resolution, handling time, and others.

Background: Globally, life expectancy is increasing, leading to an equal proportion of elderly and young individuals, which carries extensive implications. In Bosnia and Herzegovina (BiH), the average age at death in 2021 was 77 years, positioning BiH in the middle of the global list of average life expectancy. Current studiesinvestigate whether the prevalence of psychiatric disorders increases or decreases with age, but results are inconsistent regarding the role of age.There is no prior research on mental disorders in the elderly population in BiH. The experience of the previous war in BiH and the post-war complex “transitional period” have been associated with specific challenges to the mental health of this population, inspiring our research topic. Objective: The aim of this study was to investigate the psychiatric morbidity in hospitalized individuals aged≥55 years. Methods: The sample consisted of all patients over age 55 treated at the Department of Psychiatry in Tuzla between January 2018 and December 2020 (N=637), divided into four age categories. Data were obtained from medical records, and for research purposes, a specific questionnaire was constructed. Results: The predominant psychiatric morbidity stemmed from the category of affective disorders, most common within the “55-64 years” age group, while organic mental disorders were more prevalent in other age groups.Substance use disorders were present in patients aged “55-64 years”, with a sharp decline in their prevalence in older age. Female participants had a significantly higher prevalence of affective, psychotic, neurotic, and stress-related disorders, whereas male participants exhibited an increased prevalence of organic mental and substance use disorders. Conclusion: In total sample, the most prevalent diagnoses belong to the category of affective disorders. Female were most frequently diagnosed with affective disorders, whereas organic mental disorders and substance use disorders prevail in male.

Introduction: In dental clinical practice, devices such as mobile phones and DSLR cameras (Digital Single Lens Reflex) are used to take intraoral and extraoral photographs. The existence of a large number of studies would allow the establishment of standards for the analysis of photographs and their wider use in daily practice in order to establish a rapid diagnosis, predictability of results and the development of teledentology during the COVID-19 pandemic. The aim of the pilot study was to determine the repeatability of point positioning in the analysis of facial symmetry in digital 2D photography. Materials and methods: One face was photographed using two different photography techniques. Points were positioned in one photo and used for each subsequent measurement. Two evaluators positioned 20 points in three time-separated periods. Results: The results suggest a relatively high degree of agreement of the point positioning provided by the two evaluators. Absolute matching of estimates was registered on 22 parameters (ICCs = 1.00), while on another 17 this value was high (ICCs >.96) Conclusion: This study shows that the values of the interclass of correlation coefficients calculated by the method of two-way random effects for each of the six indices are higher than the values of the lower limit of acceptability (ICC> 0.70). It is necessary to do additional research that will include a larger sample and different phone models to establish the diagnosis of facial asymmetry and the development of teledentistry.

T. Uzunović, Eray A. Baran, İlkay Turaç Özçelik, Minoru Yokoyama, Tomoyuki Shimono, Asif Šabanović

Owing to the increasing engagement of service robots in everyday life, significant requirements are imposed on their control systems to ensure safe interaction between robots and humans. The stiffness of the motion executed by the service robots is not high, as with industrial robots, but has to be variable depending on the defined task. Therefore, a service robot needs to have soft actuation, delivering “human-like” motion dependant on the interaction force between the robot and its environment. Such an operation requires switching from the trajectory tracking (position control) mode to the interaction (force control) mode, and vice versa. Conventional control methods, based on hybrid position/force control, or switching between a position and force controller, may fail short in these cases. Thus, we have previously proposed a new control method, denoted as universal motion controller, that merges the position and force control into a single control structure. The control method is elaborated in this article, and its experimental validation is presented for the first time for multi-degree-of-freedom systems.

Darko Tipurić, M. Marić, María Ángeles, Ph.D Montoro Sanchez, Ph.D Peter J. Baldacchino, Ph.D Duke Bristow, Ph.D Vincent Cassar, Ph .D Katarina Djulić et al.

Džafer Alibegović, Nejra Hadžiahmetović, Lejla Dedović

From the pure health crisis that countries faced at the very begin­ning of the COVID-19 pandemic, in later stages it led to the creation of multi­ple economic and financial vulnerabilities. When the world economies start­ed recovering from the pandemic negative impacts, Russia started its inva­sion of Ukraine. The study aims to add to the growing body of literature on the topic of crises caused by the COVID-19 and Russian–Ukraine war by ana­lyzing and comparing the volatility of the world’s leading stock market per­formance benchmarks in the pre-crisis and crisis periods. For the analysis, Levene’s test is used to check the homogeneity/heterogeneity of variances of stock market returns. Analysis shows that all indexes performed better in the Russian–Ukraine crisis compared to the COVID-19 crisis, i.e., the volatili­ty of returns of all indexes is significantly lower in the Russian-Ukraine crisis compared to the COVID-19 crisis.

This paper describes influences of heat input on leg size of pulsed GMAW fillet welds of unalloyed steel with thicknesses of 4 mm, in horizontal and overhead position. Varied parameters were welding current and speed, while voltage and current profile were predefined by welding equipment manufacturer. Influence is described through models based on linear regression analysis. Comparison is made between developed models, as well as with those available in literature.

O. Sinanović, Muhamed Lepuzanovic, Edin Bašagić, M. Muftić, Sedjad Kahrić

Background: Corona infection is primarily a respiratory disease, but the SARS-CoV-2 virus also penetrates other organs, causing various symptoms, including olfactory and gustatory dysfunction, which is why we can consider COVID-19 as a multisystem disease. Aim: To present review of some aspects of the olfactory and gustatory dysfunction in SARS-CoV- infection. Methods: The article has an analytical character and review of the literature. Results and Discussion: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has a high similarity with SARS-CoV-1 and uses the same receptors to enter the human body (angiotensin-converting enzyme 2/ACE2). COVID-19 is primarily a disease of the respiratory system, but SARS-CoV-2 also penetrates the other organs including central nervous system (CNS). Patients with SARS-CoV-2 infection can experience a range of clinical manifestations, from no symptoms to critical illness. The entry of the virus into the brain can lead to different neurological and psychiatric manifestations, including loss of smell (anosmia) and the loss of taste (ageusia). The frequency of anosmia and ageusia in patients with COVID-19 varies widely, from 10 to 65%, being the primary symptom in about 12% of patients. For now, the etiopathogenesis of anosmia and ageusia in SARS-CoV-2 infection is still unknown. Most of the analyzed subjects reported olfactory recovery. However, anosmia and ageusia can last several months or even longer. While most patients are expected to recover their sense of smell or taste within the first three months, a major subpopulation of patients might develop long lasting dysfunction. Although a substantial proportion of patients with Covid-19 might develop long lasting of diferent level of ansomia and ageusia it is uncertain what proportion of patients develop persistent dysfunction. Anosmia/ageusia can be as an important risk factor for fog, anxiety, and depression that may show a prolonged and/or delayed impact. However, we do not yet know what long-term effects these disorders may have on the central nervous system and mental health in general. Conclusion: The COVID-19 is primarily a disease of the respiratory system, but SARS-CoV-2 also penetrates other organs (multisystem disease), causing various symptoms, including olfactory and gustatory dysfunction. The frequency of anosmia and ageusia in patients with COVID-19 is common but according to different papaers varies widely, from 10 to 65%, being the primary symptom in about 12% of patients. Most of the analyzed subjects reported olfactory recovery. However, anosmia and ageusia can last several months or even longer. We do not yet know what long-term consequences these disorders may have on the central nervous system and mental health in general.

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