BACKGROUND We aim to compare the incidence and risk factors for biliary anastomotic stricture (BAS) in patients undergoing orthotopic liver transplant (OLT) with and without transcystic externalised trans-anastomotic biliary stenting. METHODS A retrospective analysis was performed of a prospective database focused on 836 cadaveric OLT. Primary outcome measures were the incidence of BAS and risk factors related to its development. RESULTS Duct-to-duct anastomosis was the most commonly performed biliary reconstruction (90.5%). Transcystic externalised trans-anastomotic biliary stenting was performed in 420 patients (62.0%), being mostly used in patients having a duct-to-duct anastomosis (63.6%). BAS was seen in 222 (32.8%) patients, with a median time to diagnosis of 145.5 days (IQR 50.3-370.5). BAS was higher in patients with a duct-to-duct reconstruction when compared to those having a bilio-enteric reconstruction (34.3% vs. 18.7%, p = 0.02). The prevalence of BAS was not significantly different between patients who were stented and those who were not (34.5% vs. 30.0% respectively, p = 0.25). Multivariable analysis showed that older donor age, transplants performed earlier in the study period, higher MELD score, and type of biliary reconstruction (duct-to-duct) were independently associated with a higher risk of BAS. CONCLUSION Transcystic externalised biliary anastomotic stenting is not associated with a reduced biliary stricture incidence in OLT.
Drawing on the stereotype content model (SCM), this study aims to explore the types and content of different brand-related stereotypes depicted in marketing communications and their influence on consumers’ brand attitudes. It offers empirically-based insights into (a) the types of brand-related stereotypes portrayed in print advertisements of brands, (b) the deployment of warmth and competence in the communicated stereotypes, and (c) the responses of consumers in terms of brand attitudes. A two-phase, mixed-method research approach is used, involving (a) content analysis of published print ads, (b) multilevel modeling and (c) qualitative interviews with consumers. Firms rely heavily on brand stereotypes and, to a lesser extent, on brand buyer/user stereotypes; brand origin stereotypes are used rather sparingly by firms. The findings further show that while both brand competence and warmth positively impact consumer attitudes, both dimensions of the brand buyer stereotype have a negative effect on consumer attitudes. Firms can benefit from the positive influence of brand competence, brand warmth and brand origin competence on consumer attitudes. Emphasizing stereotypical dimensions of brand buyers/users is likely to be counterproductive. This is the first study using the SCM that simultaneously investigates brand-related stereotypes from a company (i.e. supply-side) and a consumer (i.e. demand-side) perspective. The findings offer insights into how communicated stereotypes (in terms of warmth and competence) of the brand origin, the brand itself and the buyer/user of the brand differentially influence consumer attitudes toward the focal brand.
Matija Murko is one of the most significant foreign researchers of Bosnian folk music. In 1909, he conducted the first field research in Bosnia and Herzegovina. Since he was unable to obtain adequate recording equipment, Murko took notes in the field and kept detailed records of his observations. He received a grant from the Balkan Commission of the Royal Academy of Sciences in Vienna to study epic poetry in Croatia and Bosnia and Herzegovina during the summers of 1912 and 1913. In 1912, he made the first phonograph recordings in northwestern Bosnia. The following year, in 1913, he continued his research in Sarajevo and western Herzegovina. He had planned to extend his work into the summer of 1914, but the outbreak of World War I prevented him from doing so. Murko later returned to Bosnia and Herzegovina in 1930 and 1931. During a well-organized three-month research period, he traveled to eastern Bosnia and Sarajevo. Murko’s recordings provide valuable insights into the performance of epic songs accompanied by the gusle and the two-stringed tambura, as well as sevdalinka songs performed with violin and saz accompaniment. This paper examines the significance of Murko’s research in Bosnia and Herzegovina, his methodological approach, and the field materials he collected.
The paper provides a comprehensive overview of the historical development of public administration as a scientific discipline, tracing the key phases of its evolution – from the theoretical distinction between politics and administration at the end of the 19th century, through the period of affirmation of universal administrative principles, to contemporary trends marked by digitalization and the Fourth Industrial Revolution. Through seven developmental stages, the authors analyze the theoretical contributions of key public administration theorists and the institutional changes that have shaped the discipline. Special emphasis is placed on the transformation of paradigms in public administration – from traditional hierarchical models to participatory, digitally oriented, and transparent governance systems. The paper also highlights current trends in the development of public administration, such as the advancement of digital services, application of artificial intelligence, citizen participation, operational transparency, and the professionalization of administrative personnel. In conclusion, the authors stress the need for continuous research, education, and innovation in order for public administration to successfully adapt to the challenges of the 21st century and remain a reliable service to citizens in a democratic society.
BACKGROUND Non-ST segment elevation myocardial infarction (NSTEMI) poses significant challenges in clinical management due to its diverse outcomes. Understanding the prognostic role of hematological parameters and derived ratios in NSTEMI patients could aid in risk stratification and improve patient care. AIM To evaluate the predictive value of hemogram-derived ratios for major adverse cardiovascular events (MACE) in NSTEMI patients, potentially improving clinical outcomes. METHODS A prospective, observational cohort study was conducted in 2021 at the Internal Medicine Clinic of the University Hospital in Tuzla, Bosnia and Herzegovina. The study included 170 patients with NSTEMI, who were divided into a group with MACE and a control group without MACE. Furthermore, the MACE group was subdivided into lethal and non-lethal groups for prognostic analysis. Alongside hematological parameters, an additional 13 hematological-derived ratios (HDRs) were monitored, and their prognostic role was investigated. RESULTS Hematological parameters did not significantly differ between non-ST segment elevation myocardial infarction (NSTEMI) patients with MACE and a control group at T1 and T2. However, significant disparities emerged in HDRs among NSTEMI patients with lethal and non-lethal outcomes post-MACE. Notably, neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) were elevated in lethal outcomes. Furthermore, C-reactive protein-to-lymphocyte ratio (CRP/Ly) at T1 (> 4.737) demonstrated predictive value [odds ratio (OR): 3.690, P = 0.024]. Both NLR at T1 (> 4.076) and T2 (> 4.667) emerged as significant predictors, with NLR at T2 exhibiting the highest diagnostic performance, as indicated by an area under the curve of 0.811 (95%CI: 0.727-0.859) and OR of 4.915 (95%CI: 1.917-12.602, P = 0.001), emphasizing its important role as a prognostic marker. CONCLUSION This study highlights the significant prognostic value of hemogram-derived indexes in predicting MACE among NSTEMI patients. During follow-up, NLR, PLR, and CRP/Ly offer important insights into the inflammatory processes underlying cardiovascular events.
Dietary acrylamide exposure potentially poses health risks, including increased cancer risk and neurotoxic effects. There is no official data on acrylamide levels in food products on the Bosnia and Herzegovina (B&H) market, making it challenging to assess the associated health risks. As a non-EU country, B&H lacks national regulations aligned with Commission Regulation (EU) 2017/2158, which establishes benchmark levels and mitigation measures for acrylamide. This study used GC-MS to assess acrylamide content in fifteen food products from the B&H market, categorised as potato crisps/sticks, biscuits/wafers, and coffee. Acrylamide levels in some potato crisps and sticks, tea rings, and plain biscuits exceeded benchmark values, while levels in butter biscuits, biscuits with inclusions, filling or coating, wafers, and instant coffee, remained within acceptable limits. The highest acrylamide level was in potato sticks (1048.3 μg/kg), and the lowest in butter biscuits (23.8 μg/kg). Potato crisps/sticks had the highest average acrylamide levels (677.5 μg/kg), followed by tea rings and plain biscuits (444.5 μg/kg). Potato-based snacks accounted for the highest estimated dietary acrylamide intake. Most products exceeding benchmark levels originated from B&H, suggesting local producers might not fully apply mitigation strategies. These findings emphasise the need for regulatory reform, regular market monitoring, and targeted mitigation efforts.
The Internet and digital platforms are often portrayed as public spaces, hosting both private conversations and discussions of public interest. Political campaigns are conducted and business transactions are also carried out there. This paper challenges this view by highlighting the differences between the Internet and traditional public places. Instead, it argues that the Internet increasingly resembles a mosaic of private domains controlled by a few powerful entities that dictate the flow of information. This paper examines the issue from the perspective of the benefits that public places provide in modern democratic societies and posits the debate within Habermas’s understanding of the public sphere, providing for differences in how public place is typically perceived regarding the Internet and especially digital platforms. Finally, it outlines the ongoing legislative debate in Bosnia and Herzegovina on this issue, with comparative insights from the legal frameworks of Serbia and Croatia.
The ECFA Higgs, electroweak, and top Factory Study ran between 2021 and 2025 as a broad effort across the experimental and theoretical particle physics communities, bringing together participants from many different proposed future collider projects. Activities across three main working groups advanced the joint development of tools and analysis techniques, fostered new considerations of detector design and optimisation, and led to a new set of studies resulting in improved projected sensitivities across a wide physics programme. This report demonstrates the significant expansion in the state-of-the-art understanding of the physics potential of future e+e- Higgs, electroweak, and top factories, and has been submitted as input to the 2025 European Strategy for Particle Physics Update.
Obična lavanda (Lavandula angustifolia Miller) je niska, višegodišnja grmasta biljka koja raste u zemljama oko zapadnog Mediterana. Potekla je iz sunčanih stjenovitih područja i prvenstveno se uzgaja zbog svojih esencijalnih ulja. Različite studije pokazale su da određene vrste ljekovitih biljaka, kao što je L. angustifolia Miller, koje sadrže linalol i linalil acetat ester, imaju blagi sedativni učinak i koriste se u aromaterapiji i fitoterapiji za ublažavanje stresa. Svrha ove studije je utvrditi antioksidacijsku aktivnost uzoraka obične lavande. Uzorci biljnog materijala prikupljeni su sa sljedećih područja: Gubavica (općina Mostar) i Šehovina (grad Mostar). Pri tome su analizirana četiri uzorka: esencijalno ulje dobiveno hidrodestilacijom biljnog materijala (Gubavica), uzorak maceriran u etil acetatu (Šehovina), prikupljeni vodeni ostatak nakon hidrodestilacije (Gubavica) te komercijalno esencijalno ulje. Određivanje antioksidacijske aktivnosti uzoraka provedeno je s pomoću sljedećih metoda: DPPH, ABTS i FRAP. Hidrodestilirano esencijalno ulje, kao i komercijalno ulje, pokazali su slabiju antioksidacijsku aktivnost, što je potvrđeno svim korištenim metodama. Slabija antioksidacijska aktivnost također je zabilježena u analizi uzorka etil acetata. Praćenjem tijeka reakcije za navedene uzorke nije bilo moguće izračunati IC50 vrijednost. Vodeni ostatak nakon hidrodestilacije pokazao je najvišu antioksidacijsku aktivnost prema svim korištenim metodama, što je potvrđeno IC50 vrijednošću prema DPPH metodi, koja je bila 0,032 ± 0,006 mg/mL, dok je za ABTS metodu IC50 vrijednost bila 0,135 ± 0,003 mg/mL. Također, prema FRAP metodi, vodeni ostatak nakon hidrodestilacije pokazao je najbolju antioksidacijsku aktivnost (1099,45 ± 25,39 mg Evit. C/g ekstrakta). Usporedbom kemijskog sastava i antioksidacijske aktivnosti ispitivanih uzoraka može se zaključiti da su za antioksidacijsko djelovanje odgovorni fenolni spojevi koji su bili sadržani u vodenom ostatku nakon hidrodestilacije esencijalnog ulja, koji je i pokazao najbolju aktivnost, a da spojevi koji čine esencijalno ulje imaju neznatnu učinkovitost kad je u pitanju određivanje antioksidacijskog kapaciteta.
The ECFA Higgs, electroweak, and top Factory Study ran between 2021 and 2025 as a broad effort across the experimental and theoretical particle physics communities, bringing together participants from many different proposed future collider projects. Activities across three main working groups advanced the joint development of tools and analysis techniques, fostered new considerations of detector design and optimisation, and led to a new set of studies resulting in improved projected sensitivities across a wide physics programme. This report demonstrates the significant expansion in the state-of-the-art understanding of the physics potential of future e+e- Higgs, electroweak, and top factories, and has been submitted as input to the 2025 European Strategy for Particle Physics Update.
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