Introduction: Multiple sclerosis is an inflammatory, autoimmune, disease of the white mass of the brain, which sometimes may involve the gray matter (subcortical and ones in the anterior horns of the spinal cord) with the chronic nature and generally with progressive course. As a possible cause of this disease state are listed genetic predisposition, early viral infections and environmental factors, with special effects of stress as a provoking factor in first episode of the disease and relapses because stress leads to modulation of the immune system and immune response to various causes. Goal: To determine the existence of intense stressful events as a factor in the development of the first episode of illness and worsening of the seizures. Material and methods: We analyzed all newly discovered cases of multiple sclerosis over a two year period (January 2010 – December 2011) during the first or second hospitalization, and worsening of seizures for previously diagnosed patients in this period. In order to confirm the MS diagnosis are taken history, neurological examination, MRI of the brain, VEP, CSF examination and for those with repeated hospitalization only follow-up of EDSS scores trough neurological examination. Results: During the two year period there were 109 newly diagnosed cases of MS from which 80 F and 29 M (ratio 2.7:1), aged 17-59 years, mean age 32.93±9.69 years and 41 patients (29 F and 12M with seizures worsening in previously diagnosed disease. Disease duration was from 6 months to 17 years. 72.94% had relapsing-remitting course of the disease (RRMS) and 27.1% had secondary progressive type (SPMS). Stress as a provoking factor preceded in 47.44% the first episode of the disease, infections (respiratory) in 18.3%, and the pregnancy with postpartum period in 8.77% women, whereas in the group of patients with previously diagnosed illness relapse (n=41) showed that the infection is most common precipitating factor which preceded relapse in 58.54% of patients, stress in 29.02%) and the pregnancy with postpartum period in 12.5% of patients. Conclusion: An intensive stressor is certainly one of the triggers for the development of Multiple Sclerosis, as the first episode and worsening of previously established disease.

Introduction: In the treatment of Multiple Sclerosis (MS) differ: treatment of relapse, treatment slow the progression of the disease (immunomodulators and immunosuppression), and symptomatic treatment. The aim: The aim of this study is to analyze the application of interferon therapy in the treatment of MS-E: Process the disease, patients with multiple sclerosis who have passed the commission for multiple sclerosis at the Neurology Clinic of Clinical Center of Sarajevo University as a reference center for referral to the Commission for multiple sclerosis from the Federal Ministry of Health in 2009 year in terms of total number examined, gender differences, diagnostic tests (MRI, CSF, EP), neurological findings and EDSS scores. Provide a section through the continuous support and education of patients during the introduction Betaferon in therapy with the goal of education for self-use and reduce the incidence of side effects of interferon therapy. Materials and methods: The material for the work they were histories of patients who are registered as patients who have undergone a commission for MS at Department of Neurology, University Clinical Center in Sarajevo. The evaluation was retrospective. It was used a specially designed form, which is usually applied to patients referred to this committee. After the collected material was carried out data processing. The study comprised 34 patients who have undergone a commission of which 16 patients received interferon therapy. Results: In 2009 at the Neurology Clinic CCUS have treated 34 patients who passed the committee for recommendation to interferon therapy (25 women and 9 men). The diagnosis of multiple sclerosis is safe based on the criteria of international panel in 2000. EDSS Average score for men was 1.8, 1.9 for women, the total EDSS score was 1.8. The gender ratio is 3:1 in women than in men. Sixteen patients received interferon by the Commission for multiple sclerosis, the Federal Ministry of Health and their therapy was initiated at the clinic. Conclusion: For the period of 2009, a total of 34 patients were examined with multiple sclerosis who received interferon treatment recommendations at the expense of the Federal Solidarity Fund at the Neurology Clinic CCUS Sarajevo. The average EDSS score was 1.8. There were no significant differences in neurological findings between patients who were previously treated with interferon and patients who were waiting for treatment.

Introduction: The intention of this work is to research whether the link between the barometer pressure and the cerebrovascular insult (CVI) exists. The stroke is the first cause of non-traumatic disability and third illness by mortality in the majority of available relevant literature. Goals: Goal of the sudy was to research all the cases of the patients who suffered from the acute stroke in the Canton of Sarajevo and those who were treated in the pre-hospital phase by Emergency Medical Institute staff and their working diagnosis was established as CVI ac. Material and methods: The criteria in the research were established for inclusion and exclusion of cases. The days with and without CVI cases were compared with the meteorological data obtained from the Hydro-meteorological Institute of Federation of Bosnia and Herzegovina . Since the approval was requested and obtained from the Hydro-meteorological Institute, all the meteorological data could be compared. The meteorological data comprise the barometer pressure measuring every day at 7 h, 14 h and 21 h. Results and discussion: In the retrospective study, there will be followed, during three years (2004, 2005 and 2006), the cases of the patients who suffered from the stroke, and, the emergency medical care was offered to them by the side of the Emergency Medical Institute of Canton of Sarajevo staff. All the cases in the Canton of Sarajevo were followed regardless of the place of incidence: whether the help was offered in Institute’s outpatient departments, patient’s flat or at public place. Due to the extensiveness of data (in the analysis comprising three years, there was the total of 1930 cases), the test of normal distribution was used. Since it was about the pre-hospital research, the acute stroke was looked at generally without division by types. The certain diagnostics by types can only be established in the hospital. Conclusion: The results in the research indicate that the extreme values of barometer pressure, regardless of their being increased ones or decreased ones, influence the increase of CVI incidence, while by comparing the average values in the days with CVI and without CVI, they did not have any influence on the CVI incidence.

Abstract Tradition is a cultural heritage that is passed down from generation to generation, and refers to their knowledge, crafts, ri tuals, moral codes, and customs. The term “traditional food’ ‘is defined as a way of preparing food and nutrition in rural families in the past up until the mid-twentieth century. Considering that Bosnia and Herzegovina is one of the strategic areas of development in tourism and the development of rural areas, the question is what was the traditional food of the Bosnian Krajina and how many traditional foods, were retained in the design of cuisine. The data was collected by survey, interviewing 50 people over the age of 70 years old. The questions were: what type of food they ate in the past, how the food was prepared, what were the customs of everyday life and during different celebrations? Furthermore, by review different menu's of 30 catering establishments it was determined the number and types of traditional foods represented in today's cuisine.The results show that the traditional lifestyle of the Bosnian Krajina was very simple and poor. The food was prepared from raw materials of vegetable origin, and very rarel y from animal, which was due to the low standard of living. The most common types of food were made from wheat and corn, and the most frequent were cooked foods. Special attention was paid to food for celebrations. Today on offer in Bosnian Krajina, there are a small number of traditional foods, but those that are offered are prepared in the traditional way. The style of presentation is impoverished, where the appearance of traditional decor, objects and ambience are most important. In the promotion of tourism Bosnian cuisine with its very different, unique and nutritional richness, could be used to help it become recognized as a tourist culinary destination and a pleasure for guests in this area.

Abstract Bosnia and Herzegovina is currently undergoing a process that will establish the standards and implementation of a new approach to food safety. The process emphasises the quality of information delivered to consumers, which is part of the new approach on quality and food saftey. Therefore, it is important to continue the successful communication with consumers. The Agency for Food Safety and all the other parties involved in the process of the food safety systems are required to adhere to the law and implement the laws and regulations, such as food labeling, which is now the responsibility of the food industry. The aim of this paper is to investigate the extent to which these laws and the regulations are implemented concerning the labeling of food products as well as what type of information is printed on the declarations in the B&H market. We also investigated the behavior of consumers towards food labeling, particularly in relation to nutritional information and health claims. The study included reviews of the declarations from three groups of food products. Random surveys of 208 consumers examined their attitudes towards the information described in the declaration. It was found that the product labels were in accordance with the standards in most cases, however, the declaration is often not visible and/or translated into appropriate languages. The results show that the 43% of consumers review the declaration, and that most of them (62%) pay attention to the shelf life. Only 16% read the nutritional information and 27% the health claims. There were statistically significant differences (ANOVA, Duncan's post-hoc test p