This paper describes the results of an experimental study in which older adult participants interacted with three monitoring technologies designed to support their ability to age in place in their own home - a camera, a stationary robot, and a mobile robot. The aim of our study was to evaluate users' perceptions of privacy and their tendencies to engage in privacy enhancing behaviors (PEBs) by comparing the three conditions. We found that privacy concerns lead older adults to change their behavior in a home environment while being monitored by cameras or embodied robots. We expected participants to engage in more PEBs when they interacted with a mobile robot, which provided embodied cues of ongoing monitoring; surprisingly, we found the opposite to be true - the camera was the condition in which participants performed more PEBs. We describe the results of quantitative and qualitative analyses of our survey, interview, and observational data and discuss the implications of our study for human-robot interaction, the study of privacy and technology, and the design of assistive robots for monitoring older adults.

Small cell lung cancer (SCLC) makes up almost 15% of all cases of lung cancer and occurs almost exclusively in individuals with a history of smoking (Blackhall & Faivre-Finn, 2011; Meyerson et al., 2004; Tamasi and Muller, 2011; Walenkamp et al., 2009). However, SCLCs differ significantly from NSCLCs in specific genetic alterations that occur. Moreover, smoking-damaged bronchial epithelia accompanying SCLCs appears to have undergone significantly more acquired genetic damage than is frequently found in NSCLCs. Two subtypes of SCLC exist: homogeneous small cell carcinoma and combined SCLC (mixture of any non-small cell type) (Meyerson et al., 2004; Tamasi and Muller, 2011). SCLC in its advanced stage has an aggressive clinical course and is commonly accompanied by paraneoplastic syndromes. Autocrine growth factors, such as neuroendocrine regulatory peptides (e.g. bombesin/gastrin-releasing peptide), are prominent in SCLC. SCLC is categorized as limited stage disease (LS) when confined to the ipsilateral hemithorax and within a single radiation port, while extensive stage disease (ES) includes metastatic disease outside the ipsilateral hemithorax (Blackhall & Faivre-Finn, 2011; Meyerson et al., 2004; Tamasi and Muller, 2011; Walenkamp et al., 2009). SCLC is sensitive to chemotherapy; response rates to front-line agents are often in the range of 60%, with approximately 10% of patients achieving a complete response, even in the setting of metastatic disease (Brambilla et al., 2009 Jemal et al., 2006). Despite this, the relapse rates are quite high and survival with currently available salvage therapy is quite modest. With current therapy, patients with LSSCLC have a median survival of 17 months and a 5-year overall survival rate of 12% , while patients with ES-SCLC have a median survival of 8.9 months, and a 5-year survival rate of approximately 2%. (Brambilla et al., 2009 Jemal et al., 2006; Tamasi and Muller, 2011). This article will review the molecular targeted agents, the genetic abnormalities, and therapeutic efficacy in SCLC.

Ibrahim Omerhodzic1, Samir Avdakovic2, Amir Nuhanovic3, Kemal Dizdarevic1 and Kresimir Rotim4 1Clinical Center University of Sarajevo, Department of Neurosurgery, Sarajevo 2EPC Elektroprivreda of Bosnia and Herzegovina, Sarajevo 3Faculty of Electrical Engineering, University of Tuzla, Tuzla 4University Hospital “Sisters of Charity”, Department of Neurosurgery, Zagreb 1,2,3Bosnia and Herzegovina 4Croatia

A study was conducted to evaluate the requirement of digestible lysine and nutrition plans for broilers with high genetic potential. Four hundred and ninety five one-day-old Cobb chicks with initial average weight of 45.6g±0.3g were used, allotted in a completely randomized design with three diets containing different levels of lysine, nine replicates, and 11 birds per experimental unit, to determine the best lysine level for the pre-starter phase (1 to 7 days old) and the best nutritional plan for the total period (1 to 21 days of age). Lysine levels did not influence broilers' feed intake. The digestible lysine intake increased linearly with increasing levels of this amino acid in the diet. Weight gain and feed conversion improved quadratically by increasing dietary levels of lysine. Digestible lysine requirement of 1-to-7-day-old male broilers is 1.30 and 1.29% for best weight gain and feed conversion, respectively, corresponding to intakes of 2.68 and 2.64g digestible lysine. The nutritional plan PN3 meets the nutritional needs of male broilers from 1 to 21 days of age.

ЗАЧЕСТЕНОСТ НА ПЕЛТЕЧЕЊЕТО КАЈ ДЕЦАТА НА УЧИЛИШНА ВОЗРАСТ СО DOWN-ОВ СИНДРОМ Невзета САЛИХОВИЌ1, Селма ХАСАНБАШИЌ2, Лејла БЕГИЌ1 1 Универзитет во Тузла, Факултет за об­ра­зо­ва­ние и рехабилитација  2 Институт за посебно образование и ре­ха­би­ли­тација на децата со интелектуална попреченост „Mеденица“, Сараево INCIDENCE OF STUTTERING IN SCHOOL-AGE CHILDREN WITH DOWN SYNDROME Nevzeta SALIHOVIC1, Selma HASANBASIC2, Leila BEGIC1 1 University of Tuzla, Faculty of Еducation and Re­habilitation 2 Institute of Special Education and Re­ha­bi­li­ta­ti­on for Children with Intellectual Disabilities "Mjedenica", Sarajevo Примено: 27.09.2011 Прифатено: 16.12.2011 UDK: 159.946.3-056.31-053.2 Recived: 27.09.2011  Accepted: 16.12.2011 Original Article Резиме Abstract Главната цел на ова истражување е да ја ис­пи­та појавата (зачестеноста) и тежината на пел­течењето помеѓу децата на училишна воз­раст со  Down-ов синдром. Примерокот беше сос­тавен од 37 машки и женски деца на училишна возраст кои беа дијагностицирани со Down синдром. Ова истражување беше спро­ведено во следните установи: Институт за посебно образование и рехабилитација на деца со  интелектуална попреченост „Mе­де­ни­ца“; Центар за образование, обука и вра­бо­ту­вање на деца со ментална ретардација, деца со аутизам и целебрална парализа „Вла­ди­мир Назор“ во Сараево; Основно учи­лиш­те за посебно образование „Зеница“; Ос­нов­но училиште „Ковачиќи“ во Сараево; Здру­же­ние на обединетата граѓанска иницијатива ДУГА од Сараево и асоцијацијата „Биди мој при­јател“ од Илијаш. Сите испитаници беа ис­питувани одделно. Резултатите покажаа дека 13,51 % од децата со Down синдром пел­течат, а крајниот резултат на сериозноста на пелтечењето покажа умерено пелтечење. Овие  резултати  покажуваат  дека  децата со Down синдром треба да бидат интензивно вклу­­­чени во терапијата за говор со цел да им се по­могне да го совладаат пелтечењето, да ја по­доб­рат секојдневната комуникација и да се по­ду­­чат како да се справуваат со оваа го­вор­на ма­на. The main purpose of this study was to examine the incidence (frequency) and stuttering severity in the school-age children with Down syndrome. The sample was consisted of 37 school-age children with Down syndrome, both male and female. The study was conducted in the following institutions: Institute of Special Education and Rehabilitation for Children with Intellectual Disabilities "Mjedenica"; Centre for Education, Training and Employment of Mentally Retarded Children, Children with Autism and Cerebral palsy "Vladimir Nazor" in Sarajevo; Primary School of Special Education „Zenica“; Primary school "Kovacici" Sarajevo; "Association of United Civic Actions – DUGA" in Sarajevo; and The Association "Be my friend" in Ilijas. All of the subjects were individually examined. The results showed that 13,51 % of the children with Down syndrome stuttered, and the total result of stuttering severity indicates a moderate stuttering. These results show that children with Down syndrome should be enrolled intensively in speech therapy in order to help them overcome their stuttering, to facilitate their everyday communication and to teach them how to cope with stuttering. Клучни зборови : зачестеност на пелте­че­ње­то, Down синдром, тежина на пелтечењето Key words: incidence of stuttering, Down syndrome, stuttering severity Адреса за кореспонденција: Невзета САЛИХОВИЌ Владимир Назор 8 75 000, Tузла, Босна и Херцеговина  E-пошта:  nevzeta@gmail.com Corresponding address: Nevzeta SALIHOVIC Vladimira Nazora 8 75 000, Tuzla, Bosnia and Herzegovina Email:  nevzeta@gmail.com

To The Editor: We commend Chung et al for an interesting original article reporting on the safety, efficacy, and long-term outcome of percutaneous cholecystostomy (PC) as of a definitive treatment for acute acalculous cholecystitis (AAC). They concluded that PC is an effective procedure and a good alternative for patients unfit to undergo immediate surgery because of the existence of severe sepsis or an underlying comorbidity. This is an excellent article with a strong impact on clinical practice. Traditionally, acute cholecystitis is mainly treated by surgical approach 1–3 but, in patients with poor general condition surgical treatment may carry a high risk of complications associated with major morbidity and mortality. Only limited data are available on PC treatment of AAC and little is known about the safety of PC in critically ill patients. Therefore, Chung’s study, which evaluates the feasibility and clinical outcome of PC in patients with AAC is of a high importance. However, AAC comprises <10% of all cases of acute cholecystitis. In over 90% of cases, acute cholecystitis is caused by cholecystolithiasis. Therefore, it is important to answer whether PC should be limited only to AAC. We had several cases of acute cholecystitis in patients with poor general condition, caused by cholecystolithiasis, which were successfully treated by PC and so we wish to add some comments regarding this topic. Our initial intention was for PC to be used as a temporizing measure whereas, awaiting resolution of sepsis and optimization of comorbidities before performing elective surgery. But, majority of those cases required no further surgical treatment after PC. Therefore, we believe that ultrasound-guided PC should be considered a reasonable option in the therapeutic spectrum for both acalculous and calculous cholecystitis and a good alternative for patients unfit to undergo immediate surgery because of severe sepsis or an underlying comorbidity.

Sideritis scardica Griseb., Lamiaceae (ironwort, mountain tea), an endemic plant of the Balkan Peninsula, has been used in traditional medicine in the treatment of antimicrobial infections, gastrointestinal complaints, inflammation and rheumatic disorders. This study reports a comparison between conventional (hydrodistillation HD and solvent extraction SE) and alternative (supercritical carbon dioxide SC CO2) extraction methods regarding the qualitative and quantitative composition of the obtained extracts as analyzed by GC and GC-MS techniques and their anitimicrobial activity. Different types of extracts were tested, the essential oil EO obtained by HD, EO-CO2 and AO-CO2 obtained by SC CO2 at different preasures 10 and 30 MPa, at 40 °C, respectively, and the fractions A, B, C and D obtained by successive solvent extraction (SE) A: ethanol, B: diethyl ether, C: ethyl acetate and D: n-butanol). While EO was characterized by the presence of the high percentage of oxygenated monoterpenes and sesquiterpenes (30.01 and 25.54%, respectively), the rest of the investigated samples were the most abundant in fatty acids and their esters and diterpenes (from 16.72 to 71.07% for fatty acids and their esters, and from 23.30 to 72.76%, for diterpenes). Microbial susceptibility tests revealed the strong to moderate activity of all investigated extracts against the tested microorganisms (MIC from 40 to 2,560 μg/mL). Although differences in the chemical compositions determined by GC and GC-MS analysis were established, the displayed antimicrobial activity was similar for the all investigated extracts.