Beech (Fagus sylvatica L.) is one of the most important forest trees in Bosnia and Herzegovina in both economic and environmental terms. The total area of forest in which beech is present is approx. 1,652,400 ha. There is a proportionate need to plant new forests and produce genetically high quality seed and saplings. Biochemical analysis of the genetic structure of eight populations of beech using ten enzyme systems from 16 isoenzyme gene loci revealed significant differences between the populations analyzed. Variance levels were high in some gene loci, while in some populations monomorphism was recorded only for individual gene loci. The average number of alleles per locus ranged from 2.1875 to 2.5625, and the average number of genotypes per locus varied from 2.6875 to 3.2500. The multilocus genetic diversity at the population level ranged from 63.276 to 162.001, and the genofund diversity varied from 1.2708 to 1.3416.The average differentiation value obtained for all populations was fairly low (Dj=5.81), indicating a percentage of overall variance of about 94.194%.

1 MS Program in Mathematics Education, Richard W. Riley College of Education and Leadership, Walden University, 155 Fifth Avenue South, Minneapolis, MN 55401, USA 2Department of Mathematical Sciences, United Arab Emirates University, P.O. Box 17551, Al-Ain, United Arab Emirates 3 Department of Mathematics, University of Rhode Island, Kingston, RI 02881, USA 4Departament de Matematica Aplicada, IUMPA, Universitat Politecnica de Valencia, Edifici 7A, 46022 Valencia, Spain

The most significant individual prognostic factor for those suffering from NSCLC is cancer invasion of regional lymph nodes, which depends on pathomorphological characteristics of the primary disease. Cellular and histological atopy of the changed tissue means good predispositions for an early lymph invasion and lymphonodular metastasizing. The aim of the paper: a standard statistical analysis which includes frequency of the degree of malignant change differentiation, metastasizing in stages N1 and N2 and the statistical dependence of the mentioned variables. Patients and methods: a retrospective analysis covered 331 patients who underwent a surgical procedure after they had been diagnosed with NSCLC and it was also based on the definite pathohistological postresectional results which included the above mentioned characteristics in a descriptive manner. Results: the average age of the total number of patients was 62.69 ± 7.47. Males were more numerous than females (4.7:1). There was a significant statistic correlation between the development of the disease and the age (ch 2 test = 493.65; p< 0.05), as well as a significant difference of age in relation to gender (p< 0.05). G2 stage of the disease was the most frequent, with participation of 58.00%, and there was a significant statistical correlation between developing the disease and the level of differentiation ( ch 2 test= 248.13; p<0.05). The invasion of the node N1 was 44.61% and of N2 4.53%. There was a statistically significant correlation between N1 and N2 metastases and the level of differentiation of cancer (ch 2 test =24.74; p=0.00 vs. ch 2 test = 16.37; p=0.01). Conclusion: the domination of G2 stage and statistically significant correlation between the levels of differentiation and regional lymphonodular invasion.