We compared plasma levels of biomarkers of inflammation (CRP) and oxidation (oxLDL), determined at study inclusion in lone atrial fibrillation (LAF) patients (48.6 ± 11.5 years; 74.0% men) and sinus rhythm controls (49.7 ± 9.3 years; 72.7% men, P > 0.05), and investigated the association of baseline CRP and oxLDL levels with the risk for vascular disease (VD) development (hypertension, cerebrovascular disease, coronary/peripheral artery disease, and pulmonary embolism) during prospective follow-up. Baseline CRP (1.2 [0.7–1.9] mg/L versus 1.1 [0.7–1.6] mg/L) and oxLDL levels (66.3 ± 21.2 U/L versus 57.1 ± 14.6 U/L) were higher in LAF patients (both P < 0.05). Following a median of 36 months, incident VD occurred in 14 (28.0%) LAF patients, all of whom developed arterial hypertension, and in 5 (11.4%) controls (hypertension, n = 4; coronary artery disease, n = 1), P < 0.05. LAF patients developed VD more frequently and at a younger age. Both CRP (HR, 2.54; 95% CI, 1.26–5.12; P = 0.009) and oxLDL (HR, 2.24; 95% CI, 1.14–4.40; P = 0.019) were multivariate predictors of incident hypertension in LAF patients, but not in the controls. Further research should clarify clinical relevance of investigated biomarkers for risk stratification and treatment of LAF patients.

In the market economy, the way in which company is managed and developed is extremly important, because every wrong or misleading decision comes at a high price. Therefore each decision that management brings should be based on precise, qualitative, timely and unambiguous information. In order to serve its purpose, after information are collected they are processed, classified and stored within the company. For effective and efficient information processing it is necessary to have an integrated set of components, called an information system. Undoubtedly, significant role in information processing for effective decision making, belongs to accounting information system. Therefore, the purpose of the study is to analyze the situation in Bosnia and Herzegovina related to the use and adoption of accounting information system and it's impact on decision making process. Questionnaire distributed to the business organizations and interviews with the managers, as a data collection method, will be used. Statistical and graphical methods will be used to demonstrate findings.

In view of recent experimental indications of violations of Lepton Flavor Universality (LFU) in B decays, we analyze constraints and implications of LFU interactions, both using an effective theory approach, and an explicit dynamical model. We show that a simple dynamical model based on a SU(2)L triplet of massive vector bosons, coupled predominantly to third generation fermions (both quarks and leptons), can significantly improve the description of present data. In particular, the model decreases the tension between data and SM predictions concerning: i) the breaking of τ-μ universality in B→D(*)ℓν decays; ii) the breaking of μ-e universality in B → Kℓ+ℓ− decays. Indirectly, the model might also decrease the discrepancy between exclusive and inclusive determinations of |Vcb| and |Vub|. The minimal version of the model is in tension with ATLAS and CMS direct searches for the new massive vectors (decaying into τ+τ− pairs), but this tension can be decreased with additional non-standard degrees of freedom. Further pre-dictions of the model both at low- and high-energies, in view of future high-statistics data, are discussed.

We analyze the bounds on the Higgs pseudo-observables following from electroweak constraints, under the assumption that the Higgs particle is the massive excitation of an SU(2)L\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\text {SU}(2)_L$$\end{document} doublet. Using such bounds, detailed predictions for h→4ℓ\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$h\rightarrow 4\ell $$\end{document} decay rates, dilepton spectra, and lepton-universality ratios are presented.

Para investigar os efeitos de rendimento do aprendizado e sua retencao, sobre uma unidade didatica de ensino do conteudo primeiros socorros para escolares, 20 estudantes do ensino fundamental, divididos em Grupo Controle (C) e Grupo Primeiros Socorros (PS), participaram do estudo. A unidade didatica contemplou o ensino da contencao de hemorragia, queimaduras e parada cardiorrespiratoria. Foi adotado um metodo avaliativo padronizado para os conteudos na pre-intervencao, 5 e 45 dias pos-intervencao. Ao contrario do grupo C, o grupo PS obteve resultados de aprendizado significativos aos 5 e 45 dias pos-intervencao (p<0,05), diferindo estatisticamente do grupo C (p<0,05).  Conclui-se que a unidade didatica de ensino foi efetiva no aprendizado dos primeiros socorros para escolares.