Intr Heart rate variability has been recognized as a parameter that partly describes autonomic nervous system modulation of cardiovascular system.Analysis of heart rate variability has been proposed as clinically important as predictive and monitoring factor in subjects with different cardiac disease conditions and in subjects who suffer from diabetes mellitus. Despite numerous clinical and experimental trials on the topic of heart rate variability in the setting of intensive care medicine there is a lack of appropriate technological facilites for routine monitoring and analysis of this phenomenon in everyday clinical practice.

E-mail still proves to be very popular and an efficient communication tool. Due to its misuse, however, managing e-mails problem for organizations and individuals. Spam, known as unwanted message, is an example of misuse. Specifically, spam is defined as the arrival of unwelcomed bulk email not being requested for by recipients. This paper compares different Machine Learning Techniques classification of spam e-mails. Random Forest (RF), C4.5 and Artificial Neural Network (ANN) were tested to determine which method provides the best results in spam e-mail classification. Our results show that RF is the best technique applied on dataset Labs, indicating that ensemble methods may have an edge in spam detection effective susceptible to is spam, also is defined messages not istaken with or religious he most email by a . Furthermore, by spam. around (which makes (Grant, 2003; Every e-mail user in America received an average of 2200 pieces of spam e-mails in 2002. In 2007 it reached 3600 pieces of spam e-mails due to increase rate of 2% per month conducted a survey revealing that a Chinese spam e-mails weekly. Due to spam e enterprises lose up to 9 billion yearly reveal that spam e-mails take about 60% of the incomin in a corporate network. With inappropriate or no countermeasures, the situation will worsen and, in the end, spam e-mails may destruct the usage of e countries are slowly starting to use anti (Gaikwad & Halkarnikar, 2014). The main argument supporting spam increase is the fact that spammers do not have any costs for it: “Because email technology allows spammers to shift the costs almost entirely to third parties, there is no incentive for the spammers to reduce the volume” (Hann, Hui, Lai, Lee, & Png, 2006) issue for spam is the annoying content they carry significant amount of spam contains some offensive materials (Maria & Ng, 2009). In China, some specialists suggest spam email measure as early as possible. However, because of 1210 Sarajevo,

Na temelju prvih osmanskih popisa u radu se daje prikaz stanja na prostoru novoosnovane nahije Mostar, neposredno nakon osmanskoga osvajanja. Izravna posljedica osvajanja bio je velik broj pustih i polupustih naselja. Povlasticama i oslobađanjem od pojedinih obveza nove su vlasti nastojale privoljeti izbjeglo stanovništvo da se vrati svojim domovima, ali i naseliti novo. Poduzete mjere pozitivno će se odraziti na povratak stanovništva, tako da će samo nekoliko godina nakon osvajanja broj pustih mjesta biti smanjen.

Aim: To determine the possible relation between intraocular pressure (IOP), central corneal thickness (CCT) and corneal resistance (CR) in kerotoconic eyes before, 3,6 and 12 months after collagen crosslinking procedure (CXL) with aim to find out does the thicker cornea means already more resistance cornea followed with higher IOP. Methods: Thirty eyes (30 patients) with central keratoconus (KC)were evaluated in retrospective cross sectional study. The corneal biomechanical parameters were taken with Wave Light Allegro Oculyzer produced by Alcon before the CXL, 3, 6 and 12 months after the procedure. IOP were checked by Goldmann applanation tonometry (GAT) before, 3, 6 and 12 months after CXL. Results: The value of IOP before the CXL was 12,0 mmHg (10,62-15,25 mmHg), 3 months later 13,5 mmHg (11,0-16,0 mmHg), 6 months 14,0 mmHg (11,0-16,0 mmHg) and 12 months later 15,0 mmHg (10,37-17,25 mmHg) and was statistically significant higher (p=0,015) comparing to the value of IOP 3 months after the CXL, IOP 12 months after CXL procedure was statistically significant higher comparing to preoperative values (p=0,010). There were no statistically significant difference between the values 3 and 6 months after CXL. The CCT before the CXL procedure was 449 (433-505,75 microns), 3 months after CXL was 420 (383-473microns, p < 0,005), 6 months later 437 (401,25-480,25, p=0,001), 12 months after CXL 437 (401-503 microns, p=0,001). However there is statistically significant difference in CCT 12 months after CXL 437 (401-503microns p=0,032) and the value of CCT 3 months later the procedure (p=0,004) and the CCT 12 months after CXL and the value of CXL 6 months after CXL (p=0,036). The value of CCT did not show any statistically significant difference 3 and 6 months postoperatively. Conclusion: After riboflavin-UVA CXL in eyes with KC there was significant decrease in central corneal thickness 3 and 6 months after the procedure and the thickness is almost the same 12 months later. However IOP is low before CXL, raising up 3 and 6 months after CXL but significant increase is seen 12 months later. It means the regular measurement of IOP could be the serious and confident indicator of increasing of corneal resistance which is the main goal of CXL treatment.

Objectives: The aim of this study was to determine sensitivity, specificity, and predictive values of sonographically demonstrated ureteral dilatation in detecting vesicoureteral reflux (VUR). Methods: Ethical approval from the Ethical Committee of Clinical Center University of Sarajevo and parental consent were obtained for this prospective study involving 120 children with history of urinary tract infections (UTIs). Ultrasound examination included the evaluation of the urinary tract, with a special emphasis on evaluation of ureteral dilatation. Voiding urosonography (VUS) was carried out according to a standard protocol with the use of ultrasound contrast agent Sono Vue of second generation. Ureteral diameter greater than 3 mm was considered pathological. Proven VUR was graded into one of three stages. Results: Infectio tracti urinarii recidivans was referral diagnosis in the majority of patients. The average age of patients was 4.33 ± 3.88 years (from 2 months to 16 years of age). VUS findings were normal in 59 (49.2%), and pathological in 61 (50.8%) patients. Statistical analysis showed significant correlation between type and grade of VUR. Our data confirmed predominance of VUR in females and in children under the age of 5. Statistically significant correlation between ureteral dilatation and the existence of VUR was found, with relatively high sensitivity (67.2%), specificity (81.4%), and high positive (78.8%) and negative predictive value (70.6%), total diagnostic accuracy of 74.2% in detecting VUR, and significantly increased probability (20 – 25%) of detecting VUR in patients with sonographically confirmed ureteral dilatation. Conclusion: Sonographically confirmed ureteral dilatation can be used as a predictor of VUR in children with UTIs, and in combination with other predictors, might find a place in an evidence-based selective strategy in children with suspected VUR.

Background: One of the complications aneurysms subarachnoid hemorrhage is the development of vasospasm, which is the leading cause of disability and death from ruptured cerebral aneurysm. Aim: To evaluate the significance of previous comorbidities on early outcome of patients with subarachnoid hemorrhage caused by rupture of a cerebral aneurysm in the prevention of vasospasm. Patients and methods: The study had prospective character in which included 50 patients, whose diagnosed with SAH caused by the rupture of a brain aneurysm in the period from 2011to 2013. Two groups of patients were formed. Group I: patients in addition to the standard initial treatment and “3H therapy” administered nimodipine at a dose of 15-30 mg / kg bw / h (3-10 ml) for the duration of the initial treatment. Group II: patients in addition to the standard initial treatment and “3H therapy” administered with MgSO4 at a dose of 12 grams in 500 ml of 0.9% NaCl / 24 h during the initial treatment. Results: Two-thirds of the patients (68%) from both groups had a good outcome measured with values according to GOS scales, GOS IV and V. The poorer outcome, GOS III had 20% patients, the GOS II was at 2% and GOS I within 10% of patients. If we analyze the impact of comorbidity on the outcome, it shows that there is a significant relationship between the presence of comorbidity and outcomes. The patients without comorbidity (83.30%) had a good outcome (GOS IV and V), the same outcome was observed (59.4%) with comorbidities, which has a statistically significant difference (p = 0.04). Patients without diabetes (32%) had a good outcome (GOS IV and V), while the percentage of patients with diabetes less frequent (2%) with a good outcome, a statistically significant difference (p = 0.009). Conclusion: The outcome of treatment 30 days after the subarachnoid hemorrhage analyzed values WFNS and GOS, is not dependent on the method of prevention and treatment of vasospasm. Most concomitant diseases in patients with SAH which, requiring additional treatment measures are arterial hypertension and diabetes mellitus. The best predictors in the initial treatment of patients with subarachnoid hemorrhage caused by rupture of a cerebral aneurysm has the presence of comorbidity, which has statistical significance.