In this article, we are initiating the hypothesis that improvements in short term energy load forecasting may rely on inclusion of data from new information sources generated outside the power grid and weather related systems. Other relevant domains of data include scheduled activities on a grid, large events and conventions in the area, equipment duty cycle schedule, data from call centers, real-time traffic, Facebook, Twitter, and other social networks feeds, and variety of city or region websites. All these distributed data sources pose information collection, integration and analysis challenges. Our approach is concentrated on complex non-cyclic events detection where detected events have a human crowd magnitude that is influencing power requirements. The proposed methodology deals with computation, transformation, modeling, and patterns detection over large volumes of partially ordered, internet based streaming multimedia signals or text messages. We are claiming that traditional approaches can be complemented and enhanced by new streaming data inclusion and analyses, where complex event detection combined with Webbased technologies improves short term load forecasting. Some preliminary experimental results, using Gowalla social network dataset, confirmed our hypothesis as a proof-of-concept, and they paved the way for further improvements by giving new dimensions of short term load forecasting process in a smart grid.

Sažetak: Jezero Modrac predstavlja hidroakumulaciju koja služi za snadbijevanje gradova Tuzle i Lukavca pitkom vodom kao i za obezbjeđivanje vode za industrijska postrojenja. Ovo jezero je najveći vodoprivredni objekat ove vrste u Bosni i Hercegovini. Poplave koje su 2014. godine, pogodile Bosnu i Hercegovinu, odnijele su ljudske živote, nanijele velike štete i izazvale ogromne gubitke na infrastrukturnim objektima, poljoprivredi i stočarstvu. Osnovni cilj ovog rada je da se izvrši analiza fizičko-hemijskih parametara vode jezera Modrac nakon poplava te da se na osnovu dobivenih vrijednosti parametara izvrši procjena uticaja vremenskih nepogoda na isto. Uzorci uzeti u septembru 2014. godine analizirani su brojnim fizikalno-hemijskim metodama a dobiveni rezultati u odnosu na analize sprovedene u periodu prije poplava jasno ukazuju na određeni stepen kontaminacije vodenog ekosistema jezera Modrac. Ključne riječi: Jezero Modrac, voda, poplave u BiH, kontaminacija, fizičko-hemijski parametri

microRNA是非编码RNA序列，20-22个核苷酸长，其在沉默基因表达中起作用。正常microRNA表达的变化可致癌。本研究阐明了卵巢癌中microRNA的表达与正常表达相比的变化，这样比较可以更好地理解卵巢癌发生。在肿瘤样品中，在680种microRNA类型中230种显示高表达，295种显示低表达，155种为非表达。当我们基于倍数增加>50分类microRNA时，我们发现microRNA有31高表达和89低表达。异常表达的巨大差异显示microRNA活性的变化程度。使用Cancerminer工具我们发现了这些异常表达microRNAs的相应的mRNA目标。我们发现，由数据过程捕获的最多的靶基因与细胞增殖和癌发生有关。

The dynamic process of the development of the immune system can in itself result in age-related immune malfunctions. In this study, we analysed lymphocyte subsets in the peripheral blood of 60 healthy donors, divided into groups of children, adolescents, and adults, focusing on effector (Teff) and regulatory (Treg) T lymphocytes and STAT1/STAT5 signalling response in helper T lymphocytes (Th) in adults, using flow cytometry. Our results demonstrate a decrease in the percentage of total Tregs and an increase in the percentage of total Teffs with age and a consequential immense increase in the Teff/Treg ratio. The increase of Teffs was most apparent in Th1, Th1Th17, and Th17CD161− subsets. Significant Th lymphocyte STAT1 expression differences were observed between children and adolescents, which were associated with the decrease in activated Tregs. Higher expression of STAT1 was found in FoxP3hi than in FoxP3low Th lymphocytes, while significant IL-2 induced STAT5 phosphorylation differences were found among the subsets of Th lymphocytes in adults. Our study demonstrates age-related changes in circulating Teff and Treg, as well as significant differences in STAT5/STAT1 signalling among FoxP3+ Th lymphocytes, providing new advances in the understanding of immunosenescence.

Este artigo resulta de pesquisa do doutorado em educacao e versa sobre a politica de avaliacao institucional na educacao tecnologica pos LDB 9.394/96, situada no macro contexto da Reforma da Educacao Superior. Sob enfoque de pesquisa qualitativa em educacao, com destaque para as pesquisas de cunho documental e oral o presente texto focaliza o Sistema de Avaliacao Institucional das Faculdades de Tecnologia (FATECs) do Centro Estadual de Educacao Tecnologica Paula Souza (CPS), na condicao de autarquia de regime especial responsavel pelo oferecimento da educacao profissional e tecnologica publica no Estado de Sao Paulo. Objetiva apresentar as concepcoes e proposicoes de avaliacao institucional expressas no discurso normativo-institucional do CPS, bem como apresentar a percepcao dos sujeitos escolares sobre os pressupostos, impactos e impasses da politica de avaliacao institucional das Faculdades de Tecnologia, no periodo de 2001 a 2007. O SAI-FATEC demanda um novo aprendizado abarcando construcoes e reconstrucoes, entre proposicoes e criticas na perspectiva de superacao dos impasses. Considera-se que a avaliacao institucional das Faculdades de Tecnologia apresenta-se como um duplo desafio pois se encontra no ponto de interseccao entre a educacao superior e a educacao profissional tecnica de nivel medio (educacao basica) a requerer a analise das politicas publicas para a educacao profissional e tecnologica.

We investigate the evolution of attosecond to femtosecond screening and emergent potentials that govern the dynamics and energetics of electrons and holes excited in the various stages of multiphoton photoemission processes and control the photoelectron yield in recently reported experiments [X. Cui, C. Wang, A. Argondizzo, S. Garrett-Roe, B. Gumhalter, and H. Petek, Nat. Phys. 10, 505 (2014)]. The study is focused on the dynamical screening of holes created in preexistent quasi-two-dimensional Shockley state bands on Ag(111) and Cu(111) surfaces and of electrons excited to the intermediate and emerging screened states. Using the formalism of self-consistent electronic response, we analyze first the effects of screening on the dynamics of photoexcited electrons and holes and then of the Coulomb correlated photoexcited pair. Special attention is paid to the correlated primary electron-hole states, which commence as transient surface excitons and develop in the course of screening into uncorrelated electrons and holes propagating in the image potential and surface state bands, respectively. The obtained results enable to establish a consistent picture of transient electron dynamics at Ag(111) and Cu(111) surfaces that are becoming accessible by the time-, energy-, and momentum-resolved pump-probe multiphoton photoelectron spectroscopies.