This study investigates the impact of infill density on the mechanical properties of fused deposition modeling (FDM) 3D-printed polylactic acid (PLA) and PLA reinforced with carbon fiber (PLA+CF) specimens, which hold industrial significance due to their applications in industries where mechanical robustness and durability are critical. Exposure to cooling lubricants is particularly relevant for environments where these materials are frequently subjected to cooling fluids, such as manufacturing plants and machine shops. This research aims to explore insights into the mechanical robustness and durability of these materials under realistic operating conditions, including prolonged exposure to cooling lubricants. Tensile tests were performed on PLA and PLA+CF specimens printed with varying infill densities (40%, 60%, 80%, and 100%). The specimens underwent tensile testing before and after exposure to cooling lubricants for 7 and 30 days, respectively. Mechanical properties such as tensile strength, maximum force, strain, and Young’s modulus were measured to evaluate the effects of infill density and lubricant exposure. Higher infill densities significantly increased tensile strength and maximum force for both PLA and PLA+CF specimens. PLA specimens showed an increase in tensile strength from 22.49 MPa at 40% infill density to 45.00 MPa at 100% infill density, representing a 100.09% enhancement. PLA+CF specimens exhibited an increase from 23.09 MPa to 42.54 MPa, marking an 84.27% improvement. After 30 days of lubricant exposure, the tensile strength of PLA specimens decreased by 15.56%, while PLA+CF specimens experienced an 18.60% reduction. Strain values exhibited minor fluctuations, indicating stable elasticity, and Young’s modulus improved significantly with higher infill densities, suggesting enhanced material stiffness. Increasing the infill density of FDM 3D-printed PLA and PLA+CF specimens significantly enhance their mechanical properties, even under prolonged exposure to cooling lubricants. These findings have significant implications for industrial applications, indicating that optimizing infill density can enhance the durability and performance of 3D-printed components. This study offers a robust foundation for further research and practical applications, highlighting the critical role of infill density in enhancing structural integrity and load-bearing capacity.
The association between movement screening and physical fitness testing in athletes is conflicting, and therefore, this study aimed to examine the relationship between Functional Movement Screen (FMS) performance and physical performance in elite female youth football players. Twenty-two players from the national U16 team of Bosnia and Herzegovina underwent FMS and physical performance tests, including speed, agility, and jump assessments. Jump and speed performance score correlated well with ASLR, while the overall FMS score was not associated with any of the performance variables. These findings suggest that while certain movement patterns may impact athletic performance, the relationship between movement screening and physical performance is delicate. Coaches and practitioners should consider individual variations and sport-specific demands when interpreting FMS results in order to optimize and maximize athlete performance and reduce injury risks.
Hodgkin lymphoma (HL) is a rare lymphoid neoplasm in which Hodgkin/Reed–Stenberg (HRS) cells are admixed with a population of non-neoplastic inflammatory cells and fibrosis. Dysregulated expressions of cell cycle regulators and transcription factors have been proven as one of the hallmarks of HL. In that context, SATB1 and p16 have been reported as potential regulators of HL progression and survival. However, to date, no studies have assessed the expression levels of SATB1 and p16 in HL in Croatian patients or their prognostic values. Therefore, we investigated the expression pattern of SATB1 and p16 in paraffin-embedded lymph node biopsies using standard immunohistochemistry. We found that 21% of the patients stained positive for SATB1, while 15% of the patients displayed positive staining for p16. Furthermore, we aimed to understand the prognostic value of each protein through the analysis of the overall survival (OS) and progression-free survival (PFS). SATB1 showed a significantly positive correlation with better OS and PFS, while p16 expression had no impact. Interestingly, when patients were stratified by a combination of the two studied markers, we found that patients in the SATB1+/p16- group tended to have the best prognosis in HL, according to statistical significance. In conclusion, SATB1 and p16 might be potentially useful as diagnostic and prognostic markers for HL.
Background: A better understanding of the peritumoral stroma changes due to tumour invasion using non-invasive diagnostic methods may improve the differentiation between benign and malignant breast lesions. This study aimed to assess the correlation between breast lesion differentiation and intra- and peritumoral shear-wave elastography (SWE) gradients. Methods: A total of 135 patients with newly diagnosed breast lesions were included. Intratumoral, subsurface, and three consecutive peritumoral SWE value measurements (with three repetitions) were performed. Intratumoral, interface, and peritumoral gradients (Gradient 1 and Gradient 2) were calculated using averaged SWE values. Statistical analysis included descriptive statistics and an ordinary one-way ANOVA to compare overall and individual gradients among Breast Imaging-Reporting and Data System (BI-RADS) 2, 3, and 5 groups. Results: Malignant tumours showed higher average SWE velocity values at the tumour centre (BI-RADS 2/3: 4.1 ± 1.8 m/s vs. BI-RADS 5: 4.9 ± 2.0 m/s, p = 0.04) and the first peritumoral area (BI-RADS 2/3: 3.4 ± 1.8 m/s vs. BI-RADS 5: 4.3 ± 1.8 m/s, p = 0.003). No significant difference was found between intratumoral gradients (0.03 ± 0.32 m/s vs. 0.0 ± 0.28 m/s; p > 0.999) or gradients across the tumour–tissue interface (−0.17 ± 0.18 m/s vs. −0.13 ± 0.35 m/s; p = 0.202). However, the first peritumoral gradient (−0.16 ± 0.24 m/s vs. −0.35 ± 0.31 m/s; p < 0.0001) and the second peritumoral gradient (−0.11 ± 0.18 m/s vs. −0.22 ± 0.28 m/s; p = 0.037) were significantly steeper in malignant tumours. The AUC was best for PTG1 (0.7358) and PTG2 (0.7039). A threshold value for peritumoral SWI PT1 above 3.76 m/s and for PTG1 below −0.238 m/s·mm−1 indicated malignancy in 90.6% of cases. Conclusions: Evaluating the peritumoral SWE gradient may improve the diagnostic pre-test probability, as malignant tumours showed a significantly steeper curve of the elasticity values in the peritumoral stroma compared to the linear regression with a relatively flat curve of benign lesions.
This research delves into the generalized Beddington host–parasitoid model, which includes an arbitrary parasitism escape function. Our analysis reveals three types of equilibria: extinction, boundary, and interior. Upon examining the parameters, we discover that the first two equilibria can be globally asymptotically stable. The boundary equilibrium undergoes period-doubling bifurcation with a stable two-cycle and a transcritical bifurcation, creating a threshold for parasitoids to invade. Furthermore, we determine the interior equilibrium’s local stability and analytically demonstrate the period-doubling and Neimark–Sacker bifurcations. We also prove the permanence of the system within a specific parameter space. The numerical simulations we conduct reveal a diverse range of dynamics for the system. Our research extends the results in [Kapçak et al., 2013] and applies to a broad class of the generalized Beddington host–parasitoid model.
Overexploitation of natural resources have caused serious environmental issues, including climate change, biodiversity loss, habitat degradation, and soil and water pollution. The Pan-European criteria and indicators for sustainable forest management offer a tool to monitor progress and report on the sustainability of forest resources at sub-national, national, and regional levels. This paper examines the institutional aspects and possibilities of application of these criteria and indicators in the forestry sector of the Federation of Bosnia and Herzegovina (FBiH), aiming to improve forestry conditions and develop a coherent forest policy. A survey of 360 forestry experts from FBiH revealed that the majority support the positive impact of implementing the Pan-European criteria and indicators in the forestry sector. It was determined that the Ministry of Agriculture, Water Management, and Forestry of FBiH should be responsible for developing and collecting data related to these criteria and indicators. However, the primary barriers to implementation include a lack of financial resources, expertise, and commitment. While the public forest administration is formally prepared to apply these criteria, its current capacities are inadequate for effective implementation. Strengthening the capacity of the public forest administration is crucial to ensure the application of the Pan-European criteria and indicators for sustainable forest management. This would enable consistent and systematic monitoring and improvement of forest resource conditions and the overall state of the forestry sector in FBiH.
Teritorija Republike Srpske i Bosne i Hercegovine je u velikoj mjeri izložena katastrofalnim rizicima usljed prirodnih nepogoda i nedovoljno razvijene infrastrukture i sistema zaštite. Prioritetni katastrofalni rizici na ovim prostorima su poplave i klizišta izazvane naglim porastom vodostaja rijeka uzrokovanog velikim količinama padavina. Prvi korak u upravljanju katastrofalnim rizicima je rano upozorenje, odnosno razvijanje sistema koji će na vrijeme upozoriti nadležne o potencijalnim nepogodama. Razvoj Interneta stvari značajno doprinosi ovom polju, budući da je upotrebom modernih tehnologija moguće pratiti stanje parametara i na udaljenim i nepristupačnim lokacijama. U ovom radu opisan je razvoj senzorskog čvora za praćenje vodostaja rijeka u cilju ranog upozorenja od poplava, baziran na Arduino GSM MKR 1400 razvojnoj ploči i ultrasoničnom senzoru MB7366. Uloga senzorskog čvora je da prati vodostaj rijeke u unaprijed definisanim trenucima i pošalje obavještenje nadležnom operateru ili instituciji.
This paper presents a comprehensive comparative analysis of Golden Section Search (GSS), Artificial Neural Network (ANN), and Adaptive Neuro Fuzzy Inference System (ANFIS), alongside well-known Perturb and Observe and Incremental Conductance (INC) Maximum Power Point Tracking (MPPT) algorithms for Photovoltaic (PV) system. The methodology involves theoretical development, simulation, and real-time experimentation using Matlab/Simulink and the Humusoft MF 634 data-acquisition card. Real-time experiments validate algorithm effectiveness under real-world conditions, facilitated by precise control mechanisms using Taraz's power electronics converter modules. The results contribute to ongoing efforts in optimizing MPPT technology and advancing the efficiency of PV systems for renewable energy generation.
A theoretical perspective on grandiose narcissism suggests four forms of it (sanctity, admiration, heroism, rivalry) and states that these forms conduce to different ways of thinking and acting. Guided by this perspective, we examined in a multinational and multicultural study (61 countries; N = 15,039) how narcissism forms are linked to cognitions and behaviors prompted by the COVID-19 pandemic. As expected, differences in cognitions and behaviors across narcissism forms emerged. For example, higher narcissistic rivalry predicted lower likelihood of enactment of COVID-19 prevention behaviors, but higher narcissistic sanctity predicted higher likelihood of enactment of COVID-19 prevention behaviors. Further, whereas the heroism, admiration, and rivalry narcissism forms acted in a typically antisocial manner, with high narcissism predicting greater endorsement of unfounded health beliefs, the sanctity form acted in a prosocial manner, with higher narcissism being linked to lower endorsement of unfounded COVID-19 health beliefs. Thus, the findings (a) support the idea of four narcissism forms acting differently, and (b) show that these differences reflect a double-edged sword, sometimes linking to an anti-social orientation, and sometimes linking to a pro-social orientation.
Breast cancer is one of the most common types of cancer among women worldwide, therefore an early and precise process of diagnostics plays an important role in improving the prognosis and outcome of treatment. The application of artificial intelligence (AI) allows faster and more precise analysis of medical imaging, which contributes to the early detection of tumors and lowers the number of false-negative results. This review article analyzed 60 scientific papers and using the most recent findings about this topic, searched for AI implementation in breast cancer research and how AI may improve overall survival outcomes for breast cancer patients.
Surface mining of coal has a negative impact on the environment that needs to be prevented, reduced, controlled, monitored by applying the management of technological processes of technical and biological recultivation after the end of exploitation works. The paper deals with the problem of multi-criteria decision-making in the process of selection of indicators that have an impact on the choice of purpose of recultivated terrain after the end of coal mining. The considered reclamation solutions represent possible alternatives. Degraded areas need to be returned to their original purpose, they should be in the function of environmental protection of the natural environment and settlements near this location. In addition, various criteria and sub-criteria that affect the choice of the most favourable solution were defined and analyzed. The final decision on land use after exploitation was made based on mathematical calculations using the multi-criteria VIKOR method.
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