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Tim Christopher Krapoth, Gina Sophie Henle, Mihrije Avdyli, Berina Bektić, K. Schwarzkopf, L. Bešić, Stefan Zeuzem, C. Welsch et al.

This study demonstrates the effectiveness of propidium iodide as a reliable marker for detecting dead or dying cells in frozen liver tissue sections. By comparing propidium iodide staining with the widely used Terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) assay, both methods showed consistent results in disease models such as alcohol-induced fibrosis and Western diet-induced fatty liver. Additionally, propidium iodide was successfully co-stained with other fluorescent markers, like phalloidin (for actin filaments) and antibodies targeting collagen, enabling detailed spatial analysis of dying cells within tissue. This multiplex approach allows for a deeper understanding of tissue organization and cell death localization, particularly in complex conditions like liver fibrosis. Moreover, our results suggest that propidium iodide staining can be applied beyond current models, offering a more accessible and cost-effective alternative to traditional methods, like TUNEL. Furthermore, its integration with other markers enables simultaneous analysis of immune responses and tissue damage, making it a powerful tool for future studies on liver disease and other inflammatory conditions. This technique has the potential to advance research into disease mechanisms and improve the evaluation of novel therapeutic strategies targeting tissue regeneration and inflammation control.

Filip Novaković, Šeherzada Šakić, Dajana Rikanović

This article examines the multifaceted implications of community service as a criminal sanction within the legal framework of Bosnia and Herzegovina. Grounded in an interdisciplinary approach, it integrates legal analysis, economic evaluation, and psychological perspectives to provide a comprehensive understanding of this alternative sanction. The legal analysis delves into the statutory provisions and judicial practices governing community service, assessing its alignment with international human rights standards and its effectiveness in promoting restorative justice. The economic evaluation leverages statistical data to measure the impact of community service on the national economy, including cost-benefit analyses and its potential to alleviate the financial burdens on the penal system. In exploring the psychological aspects, the article investigates the rehabilitative potential of community service. The article highlights the role of community service in fostering a sense of responsibility, improving self-esteem, and reducing recidivism rates. It also considers the challenges and limitations of implementing this sanction, including potential stigmatization and the necessity for adequate support systems. Through a thorough analysis of these dimensions, the article aims to contribute to the ongoing discourse on criminal justice reform in Bosnia and Herzegovina.

M. Steinberg, Medina Bandic, Sacha Szkudlarek, C. G. Almudéver, Aritra Sarkar, Sebastian Feld

Marija Šimić Prskalo, Zrinko Prskalo, Željka Tomić, T. Tomić

SUMMARY This study aimed to evaluate retinal nerve fiber layer thickness in exfoliation syndrome (XFS), present unilaterally, using optical coherence tomography (OCT). This prospective study included 90 examinees with unilateral syndrome. However, examinees with higher intraocular pressure or findings implicative of glaucoma were excluded from the study, as well as examinees with optic nerve changes. In individuals with unilateral XFS, OCT findings were compared between the two groups: the affected eye group and the fellow eye group. The study results show that the average thinning of the retinal nerve fiber layer, especially in the inferior and superior quadrants, has not resulted in visual field defects in examinees with unilateral XFS. In the group of eyes without XFS, 85.55% exhibited reference inferior quadrant thickness values, and 91.11% exhibited reference superior quadrant thickness values. In the group of eyes with manifest XFS, 82.22% exhibited reference inferior quadrant thickness values, and 88.88% exhibited reference superior quadrant thickness values. Most examinees in both groups had normal average retinal nerve fiber layer (RNFL) thickness (72.22%). In examinees with clinically unilateral XFS, RNFL thinning occurs in both eyes before XFS becomes bilateral and before hypertensive intraocular pressure can be measured.

SUMMARY The aim of the present study was to assess mild cognitive impairment (MCI) and cardiometabolic risk factors (CMRF) in Bosnian and Herzegovinian patients with heart failure (HF). This study included 80 patients with HF and 40 healthy controls. Montreal Cognitive Assessment (MoCA) testing was used to evaluate cognitive function. Abdominal obesity was assessed by waist circumference, and hypertension was assessed by the auscultatory method. Data on other CMRF and comorbidities, such as diabetes, smoking, alcohol consumption, and atrial fibrillation (AF), were gathered with a specially designed questionnaire. Lipids, C-reactive protein (CRP), and fibrinogen were assessed with standard laboratory methods. Student, Mann-Whitney, and Chi-square tests were used to determine significant differences between groups. Associations between categorical variables and correlation coefficients were assessed by the Chi-square and Spearman test, respectively. The prevalence of MCI in patients with HF was 77.5%. We found significant associations between MCI and diabetes, hypertension, AF, and smoking in patients with HF. We found no significant associations between MCI, abdominal obesity, and alcohol consumption. A significant positive correlation between MCI and total cholesterol was observed in patients with HF. Furthermore, a lower MoCA score was associated with higher values of CRP and fibrinogen in HF patients. The present study showed a high prevalence of MCI in Bosnian and Herzegovinian HF patients as well as its association with various CMRFs. These results suggest it is necessary to begin MCI screening in HF patients, especially since data from the literature point to improvement in cognitive performance with appropriate HF and concomitant CMRF treatment.

H. Talić, M. Ćehić

The favorable characteristics of veneer boards—plywood—enable their wide application. There is also the possibility of enhancing plywood, such as by coating it with various films, applying coatings, reinforcing it with fibers from different materials, and using improved adhesive formulas. Basalt fibers, as a natural and environmentally friendly material, are used in various forms with quite good characteristics. Results from various tests conducted in recent years indicate an improvement in the mechanical properties of composite boards, including plywood reinforced with fibers like basalt fibers. These tests were focused on determining the position and contribution of basalt fibers in the board’s structure, as well as the application of certain environmentally friendly adhesives. For this study, samples of composite material based on wood, specifically plywood reinforced with a basalt mesh, were prepared. The basalt mesh was placed within the plywood structure in various combinations of position and amount. Subsequently, a three-point bending strength test was conducted to determine the impact of the basalt mesh on the strength of the plywood. The increase in strength opens up possibilities for expanded use, material savings, and a reduction in the overall weight of the structure, which is crucial in certain applications of such boards.

Petra Kovačević, Ivana Gusar, Marija Ljubičić, Nika Samardžić, Doroteja Caktaš, Mateja Lovrić, Klara Lauš, Petra Pantalon et al.

SUMMARY The aim of this cross-sectional study was to determine the knowledge, attitudes and behavior of medical students in relation to COVID-19 according to different medical schools and duration of studies. A validated questionnaire was administered to 192 medical students at two universities in Croatia and one from Bosnia and Herzegovina. Fisher-Freeman-Halton and Kruskal-Wallis tests were used to examine differences among study groups. The association of variables was tested with a linear regression model. A negative correlation was found between adherence to measures and attitudes (ß=-0.36; p<0.001). Studying at the University of Zagreb was positively associated with students’ knowledge about COVID-19 (ß=0.24; p=0.033) but negatively with students’ attitudes (ß= 0.26; p=0.013). Compared to the last study year students, second-year students had lower knowledge (ß=-0.28; p=0.040) and statistically nonsignificant negative attitudes (ß=-0.24; p=0.055). Fifth-year students had more negative attitudes (ß=-0.24; p=0.008) compared to sixth-year students. The association between knowledge and attitudes was weak and statistically borderline nonsignificant (ß=0.14; p=0.056). The lack of association between knowledge and attitudes requires additional research to identify the potential factors that favor the formation of attitudes toward appropriate protection against COVID-19.

Enzo Marino, M. Gkantou, A. Malekjafarian, Seevani Bali, C. Baniotopoulos, Jeroen van Beeck, Ruben Paul Borg, N. Bruschi et al.

Floating Modular Energy Islands (FMEIs) are modularized, interconnected floating structures that function together to produce, store, possibly convert and transport renewable energy. Recent technological advancements in the offshore energy sector indicate that the concept of floating offshore energy islands has the potential to become more cost-effective and more widespread than previously anticipated. This review is specifically meant as a basis for the development of new approaches to the sustainable exploitation of multi-energy sources in the offshore environment leveraging the know-how of existing technologies and, at the same time, exploring new solutions for the specific challenges of FMEIs. The paper critically analyzes the current state of data-driven approaches and structural health monitoring techniques in the offshore energy sector. It also covers topics such as met-ocean data, loads estimation, platform dynamics, coupling actions, nonlinear dynamics of mooring lines, modelling considerations, and control of electrical subsystems. It is believed that this systematic and multidisciplinary review will facilitate synergies and further enhance research and development of offshore renewable energies.

M. Muratovic, Joseph T. Engelbrecht, P. Simka, Paweł Pietrzak, Fabian Mächler, Stefan Erismann, Christian M. Franck

Currently, there is significant effort worldwide in the research and development of <inline-formula><tex-math notation="LaTeX">$\mathrm{{SF}}_{6}$</tex-math></inline-formula>-free high-voltage circuit breakers, both in academia and industry. One of the most important switching capabilities is thermal current interruption, a process that, in modern self-blast breakers, strongly depends on the coupled effects of nozzle geometry, nozzle ablation, backheating, pressure build-up and gas outflow, as well as contact and puffer cylinder motion actuated through the drive. Previously published investigations on the thermal interruption performance of novel switching gases have used such designs, however, due to the many coupled processes, it is not possible to control the interruption conditions in order to make a full and comparative evaluation of different <inline-formula><tex-math notation="LaTeX">$\mathrm{{SF}}_{6}$</tex-math></inline-formula> alternative gas mixtures. The aim of the present contribution is to present an experimental circuit breaker tailored for use in basic experiments that allow for an unbiased comparison of properties of alternative gas mixtures relevant for current interruption. The breaker is based on a novel puffer design with an overpressure relief valve that allows the contact stroke and blow pressure to be predicted, controlled and adjusted over a wide parameter range at current zero. This contribution lists the requirements for such an experimental circuit breaker and focuses on its design realization. Experimental validation is given that this device can be used in benchmarking the interruption characteristics of <inline-formula><tex-math notation="LaTeX">$\mathrm{{SF}}_{6}$</tex-math></inline-formula> alternatives. Systematic comparison of the thermal interruption performance of <inline-formula><tex-math notation="LaTeX">$\mathrm{{SF}}_{6}$</tex-math></inline-formula> alternatives and investigations of the processes around current zero will be reported in other publications.

The incorporation of waste glass as a component in clinker production presents a sustainable approach to addressing critical challenges in the cement industry, including the reduction of CO2 emissions and effective waste management. Waste glass, characterized by its high silica content and alkali properties, can serve as an alternative alkali source in clinker manufacturing, replacing traditional raw materials and regulating the alkali-sulphur ratio. This dual functionality not only optimizes the chemical balance in the kiln process but also enhances clinker quality by controlling phase formation. The utilization of waste materials in industrial processes is increasingly significant in promoting circular economy principles. Integrating waste glass reduces the dependence on natural raw materials such as limestone and clay, which are associated with high energy and CO2 emission intensities during production. Furthermore, waste glass contributes to a reduction in the carbon footprint of cement production by facilitating lower-temperature clinkering, thus cutting energy consumption and greenhouse gas emissions. This study highlights the potential of waste glass as a viable alternative in clinker production, emphasizing its importance in achieving sustainability goals. Beyond the environmental benefits, adopting waste materials in industrial applications contributes to waste diversion from landfills, resource conservation, and cost efficiencies, aligning with global efforts to mitigate climate change and promote sustainable development.

Damira Vranešić Hadžimehmedović, Slobodan Klacar, Edin Mirvić, Haris Alič, Marko Đurović, Dino Musa

The aim of this research was to examine whether there is a statistically significant relationship between shoulder flexibility, anthropometric characteristics and swimming speed short distance in kinesiology students. The study included 16 participants 22 years old, male and female with an average body weight 77.7±16,42 kg and 179±9 cm. All students included in the research attended swimming class in the third semester at the Faculty of Kinesiology University of Sarajevo. The study was applied to 5 measuring instruments: measuring instruments for the assessment of flexibility (2); Measuring instruments for the evaluation of morphological characteristics (2); Measuring instrument for the assessments of swimming speed (1). Spearman's correlation coefficient was used to determine the level of interconnection for assessing the relationship between two variables. Data collection for shoulder flexibility was measured using a shoulder elevation test, and stick rotation test, while swimming speed was measured with a digital stopwatch. The analysis of the results did not demonstrate a single significant feature that would allow the confirmation of the assumptions about the significant relations between flexibility and performance in swimming.

The beneficial effect of thermomineral (sulfur) water in the treatment of degenerative rheumatic diseases of the peripheral joints is the result of the incorporation of sulfur in the form of sulfates and sulfides into the cartilaginous parts of the joints. The aim research is to examine the therapeutic effects of thermomineral-sulfur water from Ilidza-Sarajevo using the iontophoresis method in osteoarthritis of the knee and compare it with the effects of the classic galvanization method. The study was observational, prospective, included 100 participants with osteoartritis of the knee, 50 in the Iontophoresis group with sulfur water (ISW) and 50 in the group where the Classic galvanization method (CG) was applied, both genders, aged between 31 and 80. The research was conducted in two Centers for Physical medicine and rehabilitation in Sarajevo Canton. The research results show that there is a statistically significant difference in the reduction of pain in patients after 10 days of therapy, using the ISW method 33%, with the CG method it is 24% (p< 0.05). After 15 days of treatment using the ISW method 57%, according to the CG method 45% (p<0.05). The increase in the range of mobility of the knee joint with the ISW method after 10 days of treatment is 13%, and with CG 10% (p=0.336). Results after 15 days of therapy with the ISW method 22%, and with CG treatment 16% (p=0.074). The use of Ilidza sulfuric water using the iontophoresis method in osteoarthritis of the knee improves the establishment of the functional ability of the knee joint.

Adis Puška, Miroslav Nedeljkovic, Andjelka Stilic, Darko Božanić

Smart technologies are increasingly used in agriculture, with drones becoming one of the key tools in agricultural production. This study aims to evaluate affordable drones for agricultural use in the Posavina region, located in northern Bosnia and Herzegovina. To determine which drones deliver the best results for small and medium-sized farms, ten criteria were used to evaluate eight drones. Through expert evaluation, relevant criteria were first established and then used to assess the drones. The selected drones are designed for crop monitoring and are priced under EUR 2000. Using the fuzzy A-SWARA (Adapted Step-wise Weight Assessment Ratio Analysis) method, it was determined that the most important criteria for drone selection are control precision, flight autonomy, and ease of use, all of which are technical attributes. The fuzzy MARCOS method revealed that the best-performing drones are also the most affordable. The drones D5, D4, and D8 demonstrated the best results. These findings were confirmed through comparative analysis and sensitivity analysis. Their features are not significantly different from those of more expensive models and can, therefore, be effectively used for smart agriculture. This study demonstrates that drones can be a valuable tool for small farms, helping to enhance agricultural practices and productivity.

Talia Weinstein, Nadine Vogelsang, Sandor Sonkodi, Itzchak Slotki, B. Martín-Carro, David Lappin, Jorge B Cannata-Andía, Uyen Huyn-Do et al.

The shortage of applications for fellowships in nephrology is a worldwide challenge. This is the first survey to explore in Europe the reasons physicians choose (and do not choose) a career in nephrology. An anonymous questionnaire was sent to the presidents of societies that are members of the European Renal Association (ERA), who invited trainees and nephrologists to respond. Statistical analysis was performed using SPSS v.26. (SPSS Inc., Chicago, IL, USA). Continuous variables were compared by Student's t-test or by one-way ANOVA. Responders included 516 (49%) females and 542 (51%) males. They comprised 278 (26%) trainees, and 780 (74%) nephrologists. The majority (64%) believe that students have an unfavourable perception of nephrology. For trainees, nephrology is not considered an attractive option due to ‘chronically ill patients’ (35%), ‘lack of contact during undergraduate training’ (37%), ‘nephrology is too challenging’ (38%), ‘poor remuneration’ (22%), ‘negative role models’ (15%), and ‘long working hours’ (14%). The factors with the greatest impact on choosing a career include a positive role model (46%), practical experience during medical school and early postgraduate training (42%). Trainees emphasize that work–life balance is very important for the younger generation. A strong mentorship along with early engagement is associated with a higher likelihood of pursuing a career in nephrology. It is crucial to create a strategy that will provide a positive experience, renew the interest in nephrology careers and ensure enough nephrologists to treat the growing number of patients with kidney disease.

Edin Smailhodzic, A. Fernandes, Nonhlanhla Dube, Monideepa Tarafdar

This study investigates inherent tensions between social media participation and the ways of life in an Indigenous community and subsequent navigation approaches. Relying on an in‐depth qualitative study and the notion of two‐eyed seeing as a theoretical approach, the study focuses on the complex relationship between social media platform participation and the ways of life in a ‘Guarani’ Indigenous community in South America. This community successfully navigates tensions between participation on social media platforms and preserving their traditional ways of life. We contribute to two streams of literature. First, we contribute to the literature on digital platforms and indigeneity showing that social media use by Indigenous communities leads to specific tensions, as these communities try to balance the use of social media with their desire to preserve their ways of life and protect the natural environment and how they navigate these tensions. Second, we contribute to the literature in relation to digital platforms and non‐economic value as we unpack social and environmental value in the context of the Indigenous community and show that non‐economic value benefits multiple entities. Overall, we contribute to a deeper understanding of how Indigenous communities navigate tensions between participation on social media and their traditional way of life. Our study also offers practical insights into how policy makers and designers of social media platforms can better meet Indigenous communities' needs.

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