Under the generalized Lindel\"{o}f hypothesis, the exponent in the error term of the prime geodesic theorem for the modular surface is reduced to $\frac{5}{8}+\varepsilon $ outside a set of finite logarithmic measure.
Given many possible forms that physics Beyond the Standard Model (BSM) could take, it is important to pursue a bottom-up approach in which as few assumptions as possible about the BSM sector are made. In this talk, we present a combined analysis of LHC Run-1 Higgs data (signal strengths) together with LEP-2 WW production measurements, in the framework of an Effective Field Theory (EFT) where the SM is extended by higher-dimensional operators suppressed by the mass scale of new physics Λ. Working under this hypothesis, important relations among Higgs and electroweak precision observables occur. We perform the first consistent analysis at the order Λ−2 in the EFT expansion keeping all the relevant operators. While the two data sets suffer from flat directions, together they impose stringent model-independent constraints on the anomalous couplings, thus showing the importance of a global analysis in the EFT framework. We also discuss challenges faced when interpreting diboson production at the LHC in the EFT context.
In the financial theory it is common to make distinction between two types of corporate value creation concept: shareholder value and stakeholder value. In shareholder systems, also known as Anglo-American concept, institutional investors, who usually own small percentages of companies' shares, exert significant influence over managers. In major stakeholder systems, marked as Continental concept, influence is shared between large shareholders, employees, customers and suppliers. The aim of this paper is to analyze influence of globalization processes and economic crises on value creation theory and practice.
In July 2015, 179 grapevine plants belonging to 16 grapevine autochthonous cultivars were assessed for sanitary status using DAS ELISA test for the presence of: Grapevine fanleaf virus (GFLV), Grapevine leafroll-associated virus 1 (GLRaV-1), Grapevine leafroll-associated virus 2 (GLRaV-2)and Grapevine leafroll-associated virus 3 (GLRaV-3). Furthermore, surveyfor the phytoplasma presence and laboratory analyses using nested-PCR/RFLP assay was conducted at the beginning of September 2015 on grapevine cultivars which were not positive in DAS ELISA test for the presence of the four viruses. Out of 179 tested plants with DAS ELISA test, 146 (81%) were positive for the presence of at least one virus. The most widespread viruses were GFLaV- 1 and GFLaV- 3 with approximately 80 % of grapevines infected. Nested–PCR/RFLP assay showed that out of 33 tested samples 2 were positive for the presence of phytoplasmas from 16SrXII group. Sanitation of infected grapevine cultivars is needed in near future.
Therapeutic response to metformin, a first‐line drug for type 2 diabetes (T2D), is highly variable, in part likely due to genetic factors. To date, metformin pharmacogenetic studies have mainly focused on the impact of variants in metformin transporter genes, with inconsistent results. To clarify the significance of these variants in glycemic response to metformin in T2D, we performed a large‐scale meta‐analysis across the cohorts of the Metformin Genetics Consortium (MetGen). Nine candidate polymorphisms in five transporter genes (organic cation transporter [OCT]1, OCT2, multidrug and toxin extrusion transporter [MATE]1, MATE2‐K, and OCTN1) were analyzed in up to 7,968 individuals. None of the variants showed a significant effect on metformin response in the primary analysis, or in the exploratory secondary analyses, when patients were stratified according to possible confounding genotypes or prescribed a daily dose of metformin. Our results suggest that candidate transporter gene variants have little contribution to variability in glycemic response to metformin in T2D.
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