Robert Steven Ledley (1926-2012) is one of the most influential Medical informatics scientists in the history of development of Medical informatics (1-3). Robert S. Ledley and his colleague Lee B. Lusted (1922-1994) wrote a seminal 1959 paper in Science that many people cite as the publication that launched the informatics field (Reasoning Foundations of Clinical Diagnosis).

Independent and safe movement includes the development of motor skills, the acquisition of basic concepts, the awareness of oneself and the awareness of the environment. The aim of the research was to determine the influence and significance of the orientation to the body of blind students, on orientation and mobility. The sample consisted of 30 blind students aged 7 to 15, placed in the internal accommodation of the Center for Children and Youth with Developmental Disabilities "Budućnost" in Derventa and the Center for Blind and Visually Impaired Children and Youth in Sarajevo. The research used an instrument for assessing the ability of the mobility of the blind, which established the initial and final levels of development of the ability to orientate towards one's own body and the mobility of blind students. For statistical data processing, descriptive statistics and t-test methods were used. The results are in favor of the final measurement, that is, after the treatment was carried out, the improvement of the orientation towards the body was determined, which influenced the orientation and mobility of the blind pupils.

Introduction: The prevalence of allergic asthma are increasing, and the clinical outcome and risk factors of immunotherapy in the treatment of allergy have not been well established. Especially, the impact of viral infection on cytokines in allergic inflammation has yet to be established. This study aimed to determine serum IL-3, IL-11 and IgE levels and blood eosinophil and neutrophil counts during a one-year follow up in patients with allergic asthma on immunotherapy and those on anti-asthmatic drugs only, in the presence of influenza-like illness.