Oncoviruses are implicated in around 20% of all human cancers including both solid and non-solid malignancies. Epstein–Barr virus (EBV) and human papillomaviruses (HPVs) are the most common oncoviruses worldwide. Currently, it is well established that onco-proteins of EBV (LMP1, LMP2A, and EBNA1) and high-risk HPVs (E5 and E6/E7) play an important role in the initiation and/or progression of several human carcinomas, including cervical, oral, and breast. More significantly, it has been recently pointed out that viral onco-proteins of EBV and high-risk HPVs can be co-present and consequently cooperate to initiate and/or amplify epithelial–mesenchymal transition (EMT), which is the hallmark of cancer progression and metastasis. This could occur by β-catenin, JAK/STAT/SRC, PI3k/Akt/mTOR, and/or RAS/MEK/ERK signaling pathways, which onco-proteins of EBV and HPVs share. This review presents the most recent advances related to EBV and high-risk HPVs onco-proteins interactions and their roles in the progression of human carcinomas especially oral and breast via the initiation of EMT.

We implement scalar and vector leptoquark (LQ) models in the universal FeynRules output (UFO) format assuming the Standard Model fermion content and conservation of baryon and lepton numbers. Scalar LQ implementations include next-to-leading order (NLO) QCD corrections. We report the NLO QCD inclusive cross sections in proton-proton collisions at 13 TeV, 14 TeV, and 27 TeV for all on-shell LQ production processes. These comprise (i) LQ pair production (pp → ΦΦ) and (ii) single LQ + lepton production (pp → Φℓ) for all initial quark flavours (u, d, s, c, and b). Vector LQ implementation includes adjustable non-minimal QCD coupling. We discuss several aspects of LQ searches at a hadron collider, emphasising the implications of SU(2) gauge invariance, electroweak and flavour constraints, on the possible signatures. Finally, we outline the high-pT search strategy for LQs recently proposed in the literature to resolve experimental anomalies in B-meson decays. In this context, we stress the importance of complementarity of the three LQ related processes, namely, pp → ΦΦ, pp → Φℓ, and pp → ℓℓ.

In recent years, Internet of Things (IoT) industry has developed rapidly thanks to the rise of the smart objects and devices with processing, sensing and actuating capabilities. In order to satisfy a broad range of applications, a variety of application layer protocols has been taken into consideration, since IoT still does not have widely accepted standard protocol. One of prime candidate solutions is HTTP, as a well-known, fundamental client-server protocol and the protocol that is the most compatible with existing network infrastructure. Due to strict IoT specific requirements, however, a detailed characterization of the performance of HTTP for IoT applications is required. This paper presents a detailed analysis of throughput and latency for HTTP/1.1 with pipelining, by evaluating the impact that pipelining factor has on the latency. Based on these performance results, we analyze whether this HTTP/1.1 model should be implemented in IoT systems with significant latency constraints.