We describe a concrete device roadmap towards a fault-tolerant quantum computing architecture based on noise-resilient, topologically protected Majorana-based qubits. Our roadmap encompasses four generations of devices: a single-qubit device that enables a measurement-based qubit benchmarking protocol; a two-qubit device that uses measurement-based braiding to perform single-qubit Clifford operations; an eight-qubit device that can be used to show an improvement of a two-qubit operation when performed on logical qubits rather than directly on physical qubits; and a topological qubit array supporting lattice surgery demonstrations on two logical qubits. Devices that enable this path require a superconductor-semiconductor heterostructure that supports a topological phase, quantum dots and coupling between those quantum dots that can create the appropriate loops for interferometric measurements, and a microwave readout system that can perform fast, low-error single-shot measurements. We describe the key design components of these qubit devices, along with the associated protocols for demonstrations of single-qubit benchmarking, Clifford gate execution, quantum error detection, and quantum error correction, which differ greatly from those in more conventional qubits. Finally, we comment on implications and advantages of this architecture for utility-scale quantum computation.

The objective of this paper is to summarize the impact of Industry 4.0 on the most representative methods and tools of Lean Six Sigma methodology. General information about the most important Lean Six Sigma methods is given so that the reader can easily understand possible scenarios when comparing the original Lean Six Sigma tools with new evolving ones. Main references to this paper were systematically analyzed and compared to Industry 4.0 principles. The assumptions about survival of Lean Six Sigma in Industry 4.0 are based on the rapid progress of Big Data and High-Performance Computing. Lean and Six Sigma will survive Industry 4.0. Lean should retain its universality with little modification or update requirements, but Six Sigma will need some adaptations. The Six Sigma will be relevant in some cases, but to survive the Big Data and smart plants, it will require some changes in its analysis, methods, and tools. The paper provides useful insight into the adaptation of Lean Six Sigma methods to Industry 4.0, by explaining possible scenarios under which the original Lean Six Sigma tools will evolve into adapted ones.

In this article, we are initiating the hypothesis that improvements in short term energy load forecasting may rely on inclusion of data from new information sources generated outside the power grid and weather related systems. Other relevant domains of data include scheduled activities on a grid, large events and conventions in the area, equipment duty cycle schedule, data from call centers, real-time traffic, Facebook, Twitter, and other social networks feeds, and variety of city or region websites. All these distributed data sources pose information collection, integration and analysis challenges. Our approach is concentrated on complex non-cyclic events detection where detected events have a human crowd magnitude that is influencing power requirements. The proposed methodology deals with computation, transformation, modeling, and patterns detection over large volumes of partially ordered, internet based streaming multimedia signals or text messages. We are claiming that traditional approaches can be complemented and enhanced by new streaming data inclusion and analyses, where complex event detection combined with Webbased technologies improves short term load forecasting. Some preliminary experimental results, using Gowalla social network dataset, confirmed our hypothesis as a proof-of-concept, and they paved the way for further improvements by giving new dimensions of short term load forecasting process in a smart grid.

We used nine complete genome sequences, from grape, poplar, Arabidopsis, soybean, lotus, apple, strawberry, cacao, and papaya, to investigate the paleohistory of rosid crops. We characterized an ancestral rosid karyotype, structured into 7/21 protochomosomes, with a minimal set of 6,250 ordered protogenes and a minimum physical coding gene space of 50 megabases. We also proposed ancestral karyotypes for the Caricaceae, Brassicaceae, Malvaceae, Fabaceae, Rosaceae, Salicaceae, and Vitaceae families with 9, 8, 10, 6, 12, 9, 12, and 19 protochromosomes, respectively. On the basis of these ancestral karyotypes and present-day species comparisons, we proposed a two-step evolutionary scenario based on allohexaploidization involving the newly characterized A, B, and C diploid progenitors leading to dominant (stable) and sensitive (plastic) genomic compartments in any modern rosid crops. Finally, a new user-friendly online tool, “DicotSyntenyViewer” (available from http://urgi.versailles.inra.fr/synteny-dicot), has been made available for accurate translational genomics in rosids.