s. After _104_____ title, _105_____ abstract is _106_____ second most read part (frequently _107_____ only other red part) of paper, and so is likely to_108_____ basis on which _109_____work is judged by uncritical readers. It is also _110_____ first part of _111_____ paper that an editor reads carefully, and it may provoke _112_____ choice of references. Like _113_____ title, _114_____ abstract will reward time spent on it and should be short, intelligible, informative, and interesting. It should be _115_____ digest of _116_____ whole paper and contain its essence. It should consist of four basic parts, which can vary individually in length. These should describe succinctly (a) why what was done was done; (b) what was done; (c) what was found; and (d) what was concluded. 117_____ permissible length may be defined by the journal in question, but 200 words is a good average target that should be exceeded only in exceptional circumstances. 118_____ Vancouver Group suggests a maximum of 150 words for _119_____unstructured abstracts and 250 for fully structured formats. The process takes time. Remember, _120_____text that is easy to read is usually hard to write. Statistical methods. 'Statistics' is _121_____ science of collecting, describing and analyzing data that are subject to random variation. It consists of two main areas: (i) descriptive statistics, whereby _122_____ collection of data is summarized in order to characterize features of its distribution, and (ii) inferential statistics, whereby these summary data are processed in order to estimate, or predict, characteristics of another (usually larger) group. Before _123_____ research study is undertaken it is important to consider the nature of _124_____ 62 Škrbić and Igić. Scr Med 2019;50(1):56-63.

This brief review describes how two complex systems, the renin-angiotensin system (RAS) and the kallikrein-kinin system (KKS), affect the retina. It emphasises the important physiological actions of components of these systems, the protective effectiveness of angiotensin I converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARB) in diabetic retinopathy and suggests as well the therapeutic possibilities for treatment of diabetic retinopathy by selective activation of bradykinin receptors (B1 and B2).

– Today, when looking at the quality of an online item, the feedback itself plays a very important role. Based on the feedback we can decide whether the desired item is good or not, get a picture of the seller and so on. Many companies that have online shops display the most positive feedback while hiding bad ones or display only a few of them. In this research, we will help people by automating the process of deciding whether a feedback is positive or negative, which will give them time for other jobs and save money for hiring people who will work on the feedback. Since feedback on online articles is very important today, the process of determining positive and negative feedback should be made as quick and easy as possible. In this research, we will show a very simple and fast way to classify feedback as positive or negative, which means that the main question of this research is how to facilitate and speed up the process of determining the polarity of the feedback. We will use NLP using Python’s library called TextBlob. The used algorithm is called Naïve Bayes, it gave the accuracy of around 80%.

Background: The purpose of this study was to assess the antiviral efficacy and safety of the direct-acting antivirals (DAAs) in therapy of chronic hepatitis C virus (HCV) infection. Methods: This real-life multi-centric study was performed at the Clinic for Infectious Diseases, University Clinical Centre of the Republic of Srpska, Banja Luka and it included a total of 89 patients. All patients received the adequate doses of ombitasvir (OBV)/ paritaprevir (PTV)/ritonavir (RTV) + dasabuvir (DSV) plus ribavirin (RBV). RBV was given to all patients except to those with HCV sub-genotype 1b. DSV was not administered to patients infected with HCV genotype 4. For the majority of patients the treatment duration was 12 weeks. For ten patients with liver cirrhosis the duration of treatment was 24 weeks. Viraemia was assessed at three points in time: at baseline, 12 or 24 weeks after the beginning of treatment (end of treatment response ETR), and 12 weeks after the end of treatment (sustained viral response SVR). Results: Complete ETR after 12 weeks of treatment was achieved in 79 patients, while in 10 high-risk patients it was achieved after 24 weeks of treatment. Full SVR was recorded in 88 patients 12 weeks after the end of treatment. This therapy was well tolerated and mild adverse effects were recorded in only 10 patients. Conclusion: Treatment of patients with chronic HCV infection with OBV/PTV/ RTV+ DSV + RBV resulted in excellent antiviral activity and mild adverse events.

The introduction of the Bologna process to European universities has stimulated the movement of students. The aim of this study was to analyse the students' motivation to learn and use English, and to explore their attitudes to using English as a lingua franca (ELF), as well as their ELF identity while studying abroad.

The purpose of the study is to defining and assessment of the impact of the determinants affecting the development of entrepreneurship in Vojvodina’s sustainable tourism. The empirical part of the study was conducted using the Survey method. The basic research instrument was a questionnaire. Its construct was based on the factor models of entrepreneurship, amended and adapted with item entries which can be deemed correspondent with particularities of the tourism environment of the AP of Vojvodina. The results indicate that the factors of Education and Partnership are the determinants with the strongest influence on the development of entrepreneurship in Vojvodina’s sustainable tourism. Factors such as education and partnership are rated with the highest impact. Partnership, education, and cooperation between all interested stakeholders are a prerequisite for sustainable tourism in Vojvodina. © 2019 EA. All rights reserved.

Lafora progressive myoclonus epilepsy (Lafora disease, LD) is a fatal autosomal recessive neurodegenerative disorder (with an onset in teenage years in previously normal adolescents). This paper represents a view of a patient diagnosed with Lafora progressive myoclonus epilepsy, over a course of seven years. A description of the initial manifestation of symptoms, doctors' attempts to combat the symptoms with drug treatment, further attempts towards reaching the correct diagnosis, the final confirmation of the Lafora diagnosis (mutation in the NHLRC1 gene), and the current state of the patient is presented. The absence of a positive family history, the lack of staff specialized in dealing with this or similar pathology, and the diagnostic inability to characterize this type of disorder in Bosnia and Herzegovina have led to a fair delay in diagnosing and beginning of an adequate pharmacological treatment. Overall, recent identification of LD cases in Bosnia and Herzegovina warrants an establishment of a Centre for Genetic Testing in order to ensure more humane counseling of an entire family whose family member(s) might be diagnosed with this devastating and currently an incurable disorder.