The Balkan Peninsula is one of Europe?s major hotspots for plant biodiversity. Although the rich flora of the Balkans has been exten?sively studied from many points of view, genome size studies have received comparatively little attention. This paper contributes to the online available Genome Size Database of Balkan Flora (GeSDaBaF; http://www.pmf.unsa.ba/gesdabaf) and updates this database with new bibliographic data on the C-values for plants in the Balkan region. Additionally, 2C DNA values determined by flow cytometry are reported for 87 accessions, encompassing 82 taxa (70 species, 11 subspecies, and one hybrid taxon, 14 of which are endemic to the Balkans and two with amphi-adriatic distribution) across 63 genera and 31 families. The newly obtained genome size values include the first data for one genus, 25 species, eight subspecies, and one hybrid taxon. These new data represent 9.99% of the 821 taxa for which nuclear DNA content has been assessed in the Balkans to date, highlighting existing knowledge gaps for future research.

Background: Coeliotomy in chelonian species is performed to gain access to the abdominal cavity and requires general anesthesia. In reptile medicine, alfaxalone and propofol are often preferred, although the usage of these drugs is limited by cost and/or vascular access. Furthermore, according to a recent study, propofol produces significant oxidative stress in red-eared sliders (Trachemys scripta elegans), and in such cases, a ketamine and medetomidine combination may provide a better choice. Case description: Three owned red-eared sliders were separately presented with a history of recent lethargy, inappetence, dyspnea, and restlessness. Findings/treatment and outcome: In these three cases of chronic dystocia, a ketamine and medetomidine combination was used to achieve anesthesia induction for surgical treatment. Additionally, intrathecal administration of lidocaine was performed to achieve a potential analgesic effect in deeper intracoelomic reproductive organs. Preoperative changes in blood parameters were observed in one animal, suggesting abnormal kidney function. The same animal showed signs of resedation postoperatively, prolonged recovery, and had a fatal outcome 48 h after the surgery with signs of kidney damage in histopathological evaluation. In the recovery period, none of the surviving animals (n=2) showed neurological or respiratory complications that could be associated with subcarapacial sinus anesthesia administration or intrathecal local anesthesia. Conclusion: According to our observations, intrathecal lidocaine administration provided sufficient analgesia during prefemoral coeliotomy and reproductive organ manipulation. These modes of anesthesia in chelonians require further investigation.

The aim of this study was to analyze the clinical course and outcome of the disease in patients with chronic obstructive pulmonary disease (COPD) who were hospitalized at the Clinic for Infectious Diseases of the University Clinical Center of the Republic of Srpska (UCCRS), in the period from November 30, 2024 to April 1, 2025, due to confirmed influenza. The study included 125 hospitalized patients with microbiologically confirmed influenza. Among them, 20.8% had COPD, of which 48% were male and 52% female, with an average age of 68.6 years and the majority had influenza A (76%), while 24% had influenza B. The mortality rate among patients with COPD was 8%, compared to 32% in patients without COPD. Laboratory findings showed higher levels of C-reactive protein and procalcitonin in patients with COPD, indicating a more pronounced inflammatory response. Additionally, COPD patients had higher levels of D-dimer, suggesting an increased tendency toward thrombosis. Radiological analyses revealed various forms of pneumonia, with 48% of COPD patients showing negative radiological findings despite elevated CRP levels. Oxygen therapy and de-obstructive treatments were more frequently administered in COPD patients, while antibiotics were included in the treatment of all COPD patients. The results suggest the need for a specific therapeutic approach in this group of patients patient group. Also, vaccination against influenza is a key preventive measure that can prevent influenza, reduce the severity of the disease if it occurs, and improve the outcome, especially in patients with COPD, who are more susceptible to more serious complications.

Background: Seasonal flu represents a significant public health challenge and cause of morbidity and mortality, especially among vulnerable populations. The aim of our study is to describe demographic and clinical characteristics of patients hospitalized for laboratory of confirmed influenza during the 2024/2025. season.Methods: The data of patients hospitalized in the Clinic for infectious diseas of the University Clinical Center of the Republic of Srpska from December 2024 to March 2025 were restrospectively analyzed. The diagnosis of influenza was confirmed by PCR testing from a nasopharyngeal swab. Data were collected on age, sex, comorbidities, laboratory findings, therapy, the need for oxygen support and mechanical ventilation, the outcome of treatment.Results: A total of 175 patients, average age 63, were hospitalized. Influenza A was confirmed by PCR test in 78 (44.6%), and Influenza B in 20 patients (11.4%). The most common symptoms on admission were fever, cough and muscle pain. Chronic diseases were present in 155 patients (88.6%), while only 12 patients (6.9%) were vaccinated against influenza. Pneumonia was radiographically diagnosed in 102 patients (58%). Antiviral therapy was used in 160 patients (91.4%). 54 patients (30.9%) required oxygen support, while 7 patients (4%) were on mechanical ventilation. A fatal outcome was recorded in 8 patients (4.6%).Conclusion: Low vaccination rate and high proportion of chronic diseases among the hospitalized indicates to patients the need for stronger vaccination promotion and early intervention in risk groups. Timely diagnosis and adequate therapy remain key factors in prevention of severe forms of disease and reduction of mortality.

Background: Medical deontology rests on two of its pillars. One is medical ethics, and the other is medical law, i.e. legal regulations that regulate work on health protection and improvement. Ethics is of exceptional importance for medicine, due to the specificity of its calling. Objective: The aim of this article was to explaine the role of medical ethics and medical right in the healthcare professional praxis. Methods: The author used important scientific and professional literature regarding medical deontology, medical ethics and medical low published in the books, monographs and papers deposited in the scientific indexed databases PubMed Central, HINARI, Embase, etc. Results and Discussion: The specificity stems, first of all, from the fact that medicine deals with human life and health, which, in itself, carries a great responsibility. The relationships established between medical professionals and patients are also specific. In this relationship, the patient is in a subordinate and dependent position, which creates preconditions for his abuse. Due to the nature of the work, it is difficult to establish external supervision or control in order to prevent these abuses. This in turn emphasizes the importance of internal supervision and control with the help of medical ethics. Medical ethics sensitizes medical professionals to problems of an ethical nature and helps them recognize and solve them. Medical ethics is, in fact, a set of principles or rules of conduct that a medical professional must follow when making decisions about what is right and wrong, what is permitted and prohibited, what is good and bad for the patient, but also for the community. Making these decisions is often not easy. Conclusion: There are ethical principles that can conflict, which leads to ethical dilemmas, which are sometimes difficult to resolve. Take, for example, the obligation of a doctor to take into account the interests of the patient and to maintain his medical confidentiality. At the same time, however, he must also take care of the interests of the community or other persons. There are cases when the health, and even the lives of those other persons, could be endangered without revealing the medical confidentiality. Medical ethics helps resolve such and similar dilemmas.

Background: During the last ten years, there has been a dysplosis in the development of digital libraries, which have taken precedence over classical libraries. Objective: With this article, we want to make a kind of comparison of classic and digital libraries, with a description of the pros and cons of both, so we can easily see their advantages and disadvantages. Methods: Authors used as source published papers deposited in indexed databases like PMC, MEDLINE, HINARI, etc. regardsing to appropriate facts about classic and digital libraries in Bosnia and Herzegovina and wordwide. Results and Discussion: Libraries, even a scientific one, must have professionally trained staff and an appropriate technological infrastructure, the main component of which is the Library Information System (BIS). It is a phrase that refers to an integrated library system, which consists of online databases, digital libraries, electronic books, magazines and various multimedia formats on which information sources are stored (hard disks, CDs, USB sticks, DVDs, etc.). In the past, libraries tended to develop means or instruments that would enable access to documentary resources on the spot, i.e. in the library itself - through the catalog. Later, a lot of effort was invested in the development of an automatic version of these local tools - by creating an online catalog for accessing data about library resources from a distance, such as, for example, (www.cobiss.ba) maintained by the National and University Library in Sarajevo (www.nub.ba) with members of the Virtual Library of Bosnia and Herzegovina (ViBBIH) consortium. Thanks to information technology, libraries were able to automate their many functions such as: acquisition, loan, material processing and other work procedures that were previously performed manually. The publishing production of databases has enabled libraries to offer users, through free access or licensing, access to the most diverse contents, Conclusion: Thus, digital libraries have numerous advantages, they are organizations that offer resources for use, include professional staff that select, organize, provide intellectual access, explain, distribute, preserve the integrity and ensure the durability of collections of digital works in such a way that they are ready and economically available for use by one or more communities. However, time steps on us every day, and so does technology, and new inventions, computers, cell phones, so I believe that we should not ignore the beauty when we pick up a book and read it. The historical value of books should not be neglected, both for our sake and for the sake of future generations.

Background: Whatever is done should be systematic, meaning to have an established system of steps from the beginning to the end of the action. Systematicity is especially important in writing a scientific research paper, because the more complex is the topic, the easier it is to make an error. In order to minimize the possibility of errors, many have proposed various mechanisms of systematicity in the form of steps. Objective: The aim and topic of this article is to describe the system of steps in writing a scientific research paper from the birth of an idea, to the publication and presentation of a scientific paper, and to present a scientific research paper as accessible, suitable for work and perhaps even as enjoyment for scientists. Methods: The author used appropriate and relevant sources - books, monographs, published articles, proceedings from the scientific conferences about preparing, publishing, and printing scientific papers which are deposited in the most influential indexed databases in the fields of science editing. Results and Discussion: Scientific research work is of great importance in the development of science, and is one of the key links in the education system, it is part of the culture of the individual and the nation, it contributes to the development of the individual and the community, and it is one of the sources of knowledge. The systematicity of writing a scientific research paper can be broken down into several parts: the scientist preparation, the preparation of the material, the performance of the action, the statistical analysis and interpretation of the data obtained from the research and their final analysis and interpretation for the purposes of publication in scientific and professional journals. The scientist preparation includes the scientist's intention, with which everything begins and which is ultimately an important measure of the quality of the work. At this stage, the scientist should not be affected by the „publish or parish“ syndrome, vanity or the desire for fame, because in these cases he may resort to means of intellectual dishonesty in research and lose honor and reputation. With the view that the works are evaluated and toward the end, we must not neglect the rest of the steps in the creation of scientific research work. Through the preparation of the material, online databases are described, which are a source of important information for anyone who wants to be involved in scientific research. Conclusion: In the step of performing the action, the very act of writing a scientific research paper, its structuring and the rules to be followed when writing the paper are described. The method of publishing the work is also described, as well as guides on how to present the work so that the message sent reaches the audience. By knowing all the steps of creating a scientific research paper, it becomes tempting and accessible to write and publish quality and practically applicable papers.

In addition to the already well-known application in metal production, electroplating, electrochemical energy sources, electrochemistry is also applied in other branches of industry. Today, electrochemical technologies for the treatment of wastewater and drinking water are increasingly present. In recent years, new advanced oxidation processes based on electrochemical technology - Electrochemical advanced oxidation processes (EAOPs), have been developed for the treatment of persistent pollutants, which cannot be removed by conventional water treatments. EAOPs are based on “in situ” electrolytic formation of strong oxidants in an electrochemical reactor, able to degrade almost all organic pollutants. Despite their effectiveness in degrading different types of pollutants, the biggest challenge for EAOPs is high electricity demand to power these systems, which can have serious consequences from both an ecological and an economic point of view. The use of electricity from the distribution network to power electrochemical reactors is the biggest barrier to achieving commercial success of this technology. A possible solution to this challenge is the application of direct solar UV radiation to produce electric energy by use of a solar photovoltaic (PV) arrays for power supply of EAOPs. The aim of the research was to demonstrate the feasibility of using EAOPs directly powered by PV systems, as a sustainable system for efficient water treatment.

This paper presents new records and noteworthy data on the following taxa in SE Europe and adjacent regions: diatom alga Achnanthidium rosenstockii, bryoparasitic fungi Arrhenia retiruga and Arrhenia spathulata, saprotrophic fungi Coccomyces dentatus and Hysterobrevium mori, liverworts Lunularia cruciata and Pallavicinia lyellii, fern Salvinia natans, monocots Eleocharis carniolica and Pseudorchis albida and dicots Biscutella laevigata, Fumana arabica, Hieracium ferdinandi-coburgii, Impatiens balfourii, and Onosma pseudoarenaria subsp. fallax

Food sovereignty is the human right to healthy and culturally appropriate food produced through ecologically sound and sustainable methods, and the right of people to define their own food and agriculture systems. Food security exists when all people, at all times, have physical and economic access to sufficient, safe, and nutritious food that meets their dietary needs and food preferences for an active and healthy life. In contrast to food security, which focuses on ensuring that enough food is available, food sovereignty emphasizes control over food production and distribution by local communities. Shifting the focus from food security to food sovereignty essentially represents a reconnection between nature, food, and people. The right to seeds is at the basis of each community’s food sovereignty, what is possible to achieve only in the system of farmers’ seeds. Farmer seed systems are a critical contribution to food sovereignty and farmers’ rights. For over 10.000 years, people have freely saved, selected, exchanged, and sold seeds, using and reusing them for sowing and food production. The farmers’ seed system is defined by the long-standing continuous renewal and free distribution of seeds and knowledge among people. Seeds are gifted, shared, or traded in informal and formal markets. These seeds are more resilient to climate change, pests, and pathogens, and they also ensure a more diverse food system and a dynamic global ecosystem. Today, farmers’ rights to seeds, crucial for their survival, are seriously threatened and are in decline worldwide. These seed systems are undermined by inadequate legislation and insufficient support from governments and public research, primarily as the result of a protected seed market based fundamentally on intellectual property rights and trade agreements. Farmers’ seed systems are vital for preservation of plant genetic diversity of all agricultural crops. It is increasingly expected that global climate change, combined with other factors, will significantly alter this agricultural biodiversity. Broad efforts will be needed to help reduce the climate vulnerability of current agricultural production systems and building more resilient and adaptive agroecosystems. The farmers’ seed system and the associated traditional agricultural practices are key factors for adaptation.

A voltage-controlled pulsed current source (VCPCS) capable of generating current pulses with four different waveforms in the time domain is presented in this article. These waveforms are the following: hyperbolic waveform in time domain (HWTD), squared HWTD (SHWTD), quasi-Dirac delta function (QDDF) based on HWTD, and QDDF based on SHWTD. The QDDF is treated as a generalized function (GF) whose limit value leads to the required shape. The controllability of the shapes and frequency of the current pulses is provided by adjustment of the parameters of saw-tooth and triangle control voltages. The design of the proposed VCPCS can be implemented in a standard CMOS technology. However, it has been prototyped here first using discrete off-the-shelf components mounted on a printed circuit board with a single supply voltage of 3.3 V. Measured results confirm the predictions of the analysis performed. Specifically, the measured ratio of the largest and the smallest HWTD current is 7.6 times larger than that in the state-of-the-art, for the same supply voltage, which is of particular importance in optical quantum random number generators (OQRNGs).

The paper is concerned with hexacyclic systems (Fn) and their M¨obius counterparts (Mn). Continuing the studies in MATCH Commun. Math. Comput. Chem. 94 (2025) 477, the characteristic polynomial and the eigenvalues of the Sombor matrix of Fn and Mn, and the respective Sombor energies are determined. Upper and lower bounds for the Sombor energy in terms of the number of hexagons are also obtained.

The hexacyclic system graph Fn is the graph derived from a linear hexagonal chain Ln with n > 1 hexagons by identifying two pairs of ends of Ln. The M¨obious hexacyclic system graph Mn is the graph derived from a linear hexagonal chain Ln with n > 1 hexagons by identifying two pairs of ends of Ln with a twist. In this paper, we compute, in a closed form, the resolvent energy, the Laplacian and the signless Laplacian resolvent energy, as well as the resolvent Estrada index and the resolvent signless Estrada index of Fn and Mn. All five indices are expressed as a rational function in the number n of hexagons, defined in terms of Chebyshev polynomials of the first and the second kind. Those expressions allow for a fast numerical computation of indices and for deducing sharp bounds on their growth.