The increasing incidence of West Nile virus (WNV) in the Euro-Mediterranean area warrants the implementation of effective surveillance programs in animals. A crucial step in the fight against the disease is the evaluation of the capacity of the veterinary labs to accurately detect the infection in animal populations. In this context, the animal virology network of the MediLabSecure project organized an external quality assessment (EQA) to evaluate the WNV molecular and serological diagnostic capacities of beneficiary veterinary labs. Laboratories from 17 Mediterranean and Black Sea countries participated. The results of the triplex real time RT-PCR for simultaneous detection and differentiation of WNV lineage 1 (L1), lineage 2 (L2) and Usutu virus (USUV) were highly satisfactory, especially for L1 and L2, with detection rates of 97.9% and 100%, respectively. For USUV, 75% of the labs reported correct results. More limitations were observed for the generic detection of flaviviruses using conventional reverse-transcription polymerase chain reaction (RT-PCR), since only 46.1% reported correct results in the whole panel. As regards the serological panel, the results were excellent for the generic detection of WNV antibodies. More variability was observed for the specific detection of IgM antibodies with a higher percentage of incorrect results mainly in samples with low titers. This EQA provides a good overview of the WNV (and USUV) diagnostic performance of the involved veterinary labs and demonstrates that the implemented training program was successful in upgrading their diagnostic capacities.

OBJECTIVE Orthodontic anomalies with impaired facial aesthetics and disturbed oral functions have a major effect on emotional and social development. It is necessary to determine the degree of acceptance of treatment. This study includes an evaluation of the Index of Orthodontic Treatment Need (IOTN) according to the Aesthetic Component (AC) of dental health in schoolchildren. METHODS The research included 300 schoolchildren (150 girls, 150 boys) with an age range from 12 to 15 years. An evaluation of the need for orthodontic treatment according to the AC consisted of a ten-grade scale illustrated with a sequence of ten intraoral photographs showing different degrees of acceptability of dental appearance. Results were expressed as absolute and relative frequencies. The Chi-square test (in the absence of the expected frequencies of Fisher's Exact test) was used for testing the significance of differences. Cohen's kappa statistic measure was used for measuring the agreement between the children and dentists. RESULTS There is a significant substantial agreement between children and dentists in assessing the need for orthodontic treatment. Differences in assessment of the degree of orthodontic anomalies by the doctor of dental medicine with respect to boys and girls, are negligible, and statistical analysis did not show any significant difference. Analysis of the need for orthodontic treatment with respect to the age of the children showed a significant difference. CONCLUSION The need for orthodontic treatment is more pronounced in older children, and there is no difference between boys and girl.

Abstract Background: The world tourism industry is subject to big changes. A number of tourists traveling steadily grows, resulting in turnover and income. The destinations, that tourists are attracted, to are numerous, and there are also newcomers who arrive to a certain destination for the first time. Nowadays, even some very distant places are on the travellers’ bucket lists. What is more, tourists are looking for authenticity, in terms of which the concept of ethno village proves to be such an example. Purpose: The purpose of this paper is to investigate how this kind of tourism is regulated in Slovenia and Bosnia and Herzegovina. The emphasis will be on the study of specific ethno villages. Methods: Regarding the article, desk analysis will be done. The data were gathered from the world web, from the World Tourism Organisation’s data and from the data gathered from Slovenian and Bosnian national statistical office as well. The Excel was used for the analyses. Two examples of an ethno village are also described. Results: The ethno village as a part of rural tourism offers great opportunities for new work posts but capacities should be used to a greater extent and the problem of seasonality should also be overcome. All the key aims of rural development must be defined by the following strategy: the development of sustainable and efficient agricultural sector, the living standard of the population who lives from agriculture, creation of social and economic conditions in the rural regions; all of it within the National strategy of the rural development. Conclusions: Tourism industry is being developing as a part of modern touristic migration. There are more and more visitors coming overseas or coming from more remote places. They stay for a short period of time and they have different expectations as before.

Abstract Over the last few decades, many countries in the world have been struggling with high indebtedness. This has been especially emphasized in periods of crisis, and this was not an exception during the last global economic crisis in 2009. The advent of the crisis has further increased the need for borrowing. Increasing indebtedness after the crisis was also characteristic of BiH economy, the country in our research focus, which had an increase of public external debt by over 100% over the last two decades. The paper focuses on the external indebtedness of Bosnia and Herzegovina (BiH) over the period 2004-2017. The empirical part relies on dynamic modelling - Vector Autoregression Model, which is used to explore total external indebtedness. The empirical investigation implies that foreign-trade exchange deficits have had the greatest impact on rising indebtedness in BiH, while movements in EURIBOR interest rates have little influence in explaining this variability. The empirical investigation implies that macroeconomic policy in BiH, if it wants to keep the external debt under control over the longer time horizon, does need to focus on deficits in its foreign exchange more. One of inevitable priorities is to work on supporting production based of export from this economy.

OBJECTIVES The goal of this study was to determine the sealing ability of MTA, Biodentine, and Fuji IX as root-end materials after ultrasonic retrograde preparation using a dye penetration method. MATERIALS AND METHODS Seventy permanent anterior teeth were used in this study. Root canals were prepared using rotary endodontic files, and obturated using the lateral condensation technique. The resection of the root apices was performed perpendicularly to the long axis, and 3 mm deep retrocavities were made by ultrasonic tips. The samples were randomly divided into three experimental groups (N=20) and two control groups (N=5). The root-end cavities were filled with mineral-trioxide aggregate (Rootdent MTA, TehnoDent, Russia) in Group 1, Biodentine (Septodont, Saint Maur des Fossés, France) in Group 2 and Fuji IX GP (GC Corporation, Tokyo, Japan) in Group 3. The retrocavities of the positive control group were left unfilled, while retrocavities in the negative control group were sealed using a flowable composite material. The samples were made transparent, and dye penetration was assessed under a stereomicroscope (x10). The data were analyzed with the Kruskal-Wallis test and the Mann-Whitney U-test. RESULTS The Biodentine group had a lower mean leakage value than the MTA and Fuji IX groups, and the difference was statistically significant (P<0.01). No statistical difference in apical microleakage was found between the MTA and Fuji IX groups (P>0.05). CONCLUSION Within the limitations of this study, it was concluded that Biodentine provides better sealing ability as a root-end material than MTA and Fuji IX. There was no statistically significant difference between the sealing ability of MTA and Fuji IX as root-end materials.

Introduction: A number of nuclear medicine procedures significantly dropped worldwide during the COVID-19 pandemic. Every nuclear medicine department has faced changed working environment in terms of the type of requested procedures, number of requests and personal protection issues. Also, some specificities emerged that affect standard operating procedures. Aim: The aim here is to present different clinical scenarios related to RT PCR molecular testing and COVID-19-associated pulmonary findings on PET/CT in oncologic patients. Methods: A case series of four patients imaged on oncologic PET/CT is presented. Short clinical history followed by description of significant PET/CT findings and their importance from the perspective of COVID-19 pandemic and interpretation of PET/CT findings is presented. Conclusion: PET/CT imaging remains of paramount importance for oncologic patients during the pandemic. Under the unprecedented circumstances, interpretation of PET/CT findings has become more complex having some specificities that must be kept in mind.

Abstract Basil (Ocimum basilicum L.), as an aromatic and medicinal plant, exhibits numerous of genotypes that have various applications in food and pharmaceutical industries. Thus, chemical composition is an important parameter for assessing the quality of basil. Hence, twelve European basil genotypes were cultivated under the same conditions, and isolated essential oils and methanol extracts were subjected to detailed chemical analyses and testing their biological activities. According to the analysis of the volatiles, all genotypes belong to linalool chemotype, and they were clustered into two groups. Rosmarinic acid was found to be the major phenylpropanoid, following with luteoin, kaempherol, and rutin. Principal component analysis of phenolic compounds indicated segregation of genotypes in two distinct groups. Biological activities of the isolated extracts were correlated with the concentrations of the actives, and it was found that naringenin, luteolin, and kaempherol are the main carriers of antioxidant activity, while the levels of linalool correlated with tyrosinase inhibition activity. Adversely, methyl chavicol showed negative correlations with both assays. Finally, it was found that Czech genotypes (Litra and Chladek), as well as Dutch (Bush) and Italian (Fino Verde Compatto) possess significant amounts of terpenoid linalool, together with flavonoids luteolin, naringenin, and kaempherol, and therefore, have strong biological activities required for their use in food and cosmetic industries.

A 31-year-old woman with hepatocellular carcinoma suffered from recurrent oesophageal variceal bleeding due to portal hypertension, which was caused by severe compression of the portal vein by metastatic lymph nodes. Endoscopic band ligation and pharmacological treatment did not suffice to prevent recurrence of variceal bleeding. Eventually, after the fifth variceal bleeding within 6 months, the patient was admitted to the intensive care unit in a haemodynamic shock. A Sengstaken-Blakemore tube was inserted and all treatment options were discussed, but only percutaneous transhepatic recanalisation of the portal vein with stent placement to reduce portal vein pressure was thought to be feasible with any chance to relieve portal vein pressure. After successful portal vein stenting, our patient did not have any recurrent bleeding in the remaining year of her life. We suggest that percutaneous transhepatic portal vein stenting may be a feasible and adequate last line treatment for complications of portal hypertension.

Current tables of wood assortments for the most important tree species in B&H were made almost 50 years ago. There is an indication that real forest wood assortments are different than the one derived from assortment tables in-use, both in terms of quality and dimensions. In the meantime, from the creation of the existing tables until today, the standards of production of forest wood assortments have changed, so that the fact of inaccuracy of the existing assortment tables is unquestionable. This continually creates a variety of problems in the ongoing operations of forestry companies. The main aim of this paper is to create wood assortment tables whose assortment of wood products will correlate with the current market conditions. The research was conducted in the area of the Canton 10 in FB&H.  A sample of 393 spruce trees was used as a database to produce this paper. The bucking of the sample trees was carried out in accordance with the valid norms and customer requirements with regards to the dimensions of forest wood products. Data processing was performed using methods of simple and multiple regressions, variance analysis as well as their combinations by the Generalized Linear Models method. Independent factors were breast diameter (DBH), technical quality class and the height of the trees. The share of wood assortments was determined through 10 different mathematical models, and it was found that all independent variables had a statistically significant influence on the dependent variables- volume of particular assortments or group of assortments. The share of logs is growing rapidly with the increase of tree diameter and decreases with decreasing of their technical quality. The influence of tree height primarily correlated with tree volume increase. Trees having better assortment quality, have tree heights higher than average for the same diameter class. The results of the research are presented in the form of tables as percentage share of wood assortment classes.  The obtained results can be used as wood assortment tables in the research area.

Summary Geographically dispersed patients, inconsistent treatment tracking, and limited infrastructure slow research for many orphan diseases. We assess the feasibility of a patient-powered study design to overcome these challenges for Castleman disease, a rare hematologic disorder. Here, we report initial results from the ACCELERATE natural history registry. ACCELERATE includes a traditional physician-reported arm and a patient-powered arm, which enables patients to directly contribute medical data and biospecimens. This study design enables successful enrollment, with the 5-year minimum enrollment goal being met in 2 years. A median of 683 clinical, laboratory, and imaging data elements are captured per patient in the patient-powered arm compared with 37 in the physician-reported arm. These data reveal subgrouping characteristics, identify off-label treatments, support treatment guidelines, and are used in 17 clinical and translational studies. This feasibility study demonstrates that the direct-to-patient design is effective for collecting natural history data and biospecimens, tracking therapies, and providing critical research infrastructure.

There is a significant demand for fast and accurate electromagnetic (EM) imaging of stroke in emergency situations. This article presents a method for encoding the raw S-parameters from the Cartesian matrix to polar grid coordinates with weighting coefficients based on the receiver antenna spatial sensitivity. The polar sensitivity encoding (PSE) scheme is based on the fact that the receiver sensitivity generally has an encoding effect and, in this case, it is applied during the transformation of S-matrices to polar grid, which is geometrically congruent with the shape of the head. The PSE scheme alleviates the need for highly accurate and intricate forward and inverse EM field solvers and mitigates the introduction of numerical errors in addition to the unavoidable experimental uncertainties. The simulation and experimental results demonstrate that the PSE method is robust to head shifts up to about 5 mm and accurate in localizing strokes in less than a second.

Dysphagia management, from screening procedures to diagnostic methods and therapeutic approaches, is about to change dramatically. This change is prompted not solely by great discoveries in medicine or physiology, but by advances in electronics and data science and close collaboration and cross-pollination between these two disciplines. In this editorial, we will provide a brief overview of the role of artificial intelligence in dysphagia management.

Purpose Safe swallowing requires adequate protection of the airway to prevent swallowed materials from entering the trachea or lungs (i.e., aspiration). Laryngeal vestibule closure (LVC) is the first line of defense against swallowed materials entering the airway. Absent LVC or mistimed/ shortened closure duration can lead to aspiration, adverse medical consequences, and even death. LVC mechanisms can be judged commonly through the videofluoroscopic swallowing study; however, this type of instrumentation exposes patients to radiation and is not available or acceptable to all patients. There is growing interest in noninvasive methods to assess/monitor swallow physiology. In this study, we hypothesized that our noninvasive sensor- based system, which has been shown to accurately track hyoid displacement and upper esophageal sphincter opening duration during swallowing, could predict laryngeal vestibule status, including the onset of LVC and the onset of laryngeal vestibule reopening, in real time and estimate the closure duration with a comparable degree of accuracy as trained human raters. Method The sensor-based system used in this study is high-resolution cervical auscultation (HRCA). Advanced machine learning techniques enable HRCA signal analysis through feature extraction and complex algorithms. A deep learning model was developed with a data set of 588 swallows from 120 patients with suspected dysphagia and further tested on 45 swallows from 16 healthy participants. Results The new technique achieved an overall mean accuracy of 74.90% and 75.48% for the two data sets, respectively, in distinguishing LVC status. Closure duration ratios between automated and gold-standard human judgment of LVC duration were 1.13 for the patient data set and 0.93 for the healthy participant data set. Conclusions This study found that HRCA signal analysis using advanced machine learning techniques can effectively predict laryngeal vestibule status (closure or opening) and further estimate LVC duration. HRCA is potentially a noninvasive tool to estimate LVC duration for diagnostic and biofeedback purposes without X-ray imaging.

Purpose – The purpose of this paper is to provide insight into the interplay between consumer ethnocentrism and social identity as concepts with significant relevance for different consumer responses in globalized environment. Design/Methodology/Approach – The paper contains analysis of theoretical foundations, based on social identity theory, as well as conceptual content analysis of selected studies that deal with both the observed concepts. Findings and implications – This paper contributes to deeper insights into the interplay between consumer ethnocentrism and identity, and provides a good foundation for explaining and predicting different consumers’ responses in the globalized environment. From the perspective of social identity theory, ethnocentrism is considered to be an important factor in maintaining social identity and preserving it in the changing environment. This proposition is confirmed by empirical studies that show a positive relation between identity and consumer ethnocentrism. On the other hand, some empirical studies reveal somewhat mixed results which indicate that consumer ethnocentrism does not always correspond with the strength of identity. Also, studies that deal with consumer ethnocentrism and identity in Marija Čutura University of Mostar, Faculty of Economics, Matice hrvatske, bb, 8800 Mostar, BOSNIA AND HERZEGOVINA, e-mail: marija.cutura@ef.sum.ba Market-Tržište Vol. 32, Special Issue, 2020, pp. 131-146 UDK 658.89:658.62 DOI http://dx.doi.org/10.22598/mt/2020.32.spec-issue.131 Review CONSUMER ETHNOCENTRISM AND SOCIAL IDENTITY: THEORETICAL BACKGROUNDS AND EMPIRICAL STUDIES OVERVIEW POTROŠAČKI ETNOCENTRIZAM I SOCIJALNI IDENTITET: TEORIJSKA POZADINA I PRIKAZ EMPIRIJSKIH STUDIJA