Background Despite ACL re-ruptures being common, research on patient experiences after knee trauma has primarily focused on the time after primary ACL reconstruction. Integrating qualitative research and patient experiences can facilitate researchers and clinicians in understanding the burden of an ACL re-rupture. The aim of the study was to explore the experiences of an ACL re-rupture journey in young active females aiming to return to knee-strenuous sports after primary ACL reconstruction. Method A two-stage partially mixed sequential dominant status design was used. Fifteen young (19.1[range 16-23] years old) female who suffered an ACL re-rupture were interviewed. Qualitative content analysis using deductive approach based on Wiese-Bjornstal’s ‘integrated model of psychological response to injury’ was used. Results The results are presented in two timelines 1) from first ACL injury to ACL re-rupture, and 2) from ACL re-rupture to present day, and further stratified according to the domains of the ‘integrated model of psychological response to injury’. Results in the first timeline are summarised into seven categories: Finding hope for the journey; Accepting my ACL injury; I succeeded; What matters now? Who am I?; Where will this end? What is going to happen? In the second timeline, eight categories were identified: Fighting spirit; A helping hand; Working hard; I am a new me; I am destroyed; Loneliness; Painful changes; and, I could have made it to the pro´s. Conclusion Young females who suffered an ACL re-rupture did not express any positive experience following their first ACL injury, however, in contrast, expressed positive experiences and personal growth after going through the ACL re-rupture journey, characterized by a lot of struggling, and ultimately lead to the experience of becoming a new, stronger person.

Irreversible arrest of brain functions including the brain stem is defined as Brain Death (BD). A bibliographic search was carried out on platforms PUBMED, LILACS, UpToDate, during the period 2017 – 2021. We have included 9 articles, from which only 45% used the graphic examination (EEG) as an aid to the assessment of brain death. Only one single article discussed quantitative results, and none of the papers discussed noise issues. The findings were classified according to a Scale of Scientific Evidence by Type of Study "Oxford Center for Evidence-Based Medicine", pointing out a few number of meta-analysis articles and integrative reviews, thus prevailing study control and case series, demonstrating the need for further studies on this subject. Consequently, the lack of systematic reviews and meta-analyses on the BD diagnosis protocol involving the EEG is clear.

Large intelligent surface-based transceivers (LISBTs), in which a spatially continuous surface is being used for signal transmission and reception, have emerged as a promising solution for improving the coverage and data rate of wireless communication systems. To realize these objectives, the acquisition of accurate channel state information (CSI) in LISBT-assisted wireless communication systems is crucial. In this paper, we propose a channel estimation scheme based on a parametric physical channel model for line-of-sight dominated communication in millimeter and terahertz wave bands. The proposed estimation scheme requires only five pilot signals to perfectly estimate the channel parameters assuming there is no noise at the receiver. In the presence of noise, we propose an iterative estimation algorithm that decreases the channel estimation error due to noise. The training overhead and computational cost of the proposed scheme do not scale with the number of antennas. The simulation results demonstrate that the proposed estimation scheme significantly outperforms other benchmark schemes.

During long periods with no precipitation, a sulfidic spring (Smrdljivec) appears in the dry bed of the Reka River before sinking into the karst underground. The study characterizes the area’s geological setting, development of microbial communities and an ecotone, and impact on the vulnerable karst ecosystem. Geological mapping of the area, stable isotopic analyses, field measurements, and physico-chemical and toxicity analyses were applied to elucidate the environmental conditions. The spring’s microbial diversity was assessed using cultivation methods, microscopy, and metagenomics. Sulfur compounds in the spring probably originate from coal layers in the vicinity. Metagenomic analyses revealed 175 distinct operational taxonomic units in spring water and biofilms. Proteobacteria predominated in developed biofilms, and a “core” microbiome was represented by methylotrophs, including Methylobacter, Methylomonas, and Methylotenera. Diatoms represented an important component of biofilm biomass. A combination of environmental factors and climatic conditions allows the formation and accessibility of emerging biodiversity hotspots and ecotones. Details of their dynamic nature, global impact, and distribution should be highlighted further and given more protection.

Now that the pandemic has entered the second phase, in which countries are adapting to the crisis, governments need to determine incentives that will contribute to the sustainability of the health system and human health. Regarding this, human resources are a significant factor, which affects the sustainability of any system, and it is important to establish a relevant motivation system that will withstand the challenges that society will face in the coming period. The aim of this paper is to analyse three dimensions of state incentives (employment program, COVID-19 bonus, training opportunities) and to examine their influence on healthcare workers’ motivation and the sustainability of the health system in the Republic of Serbia. The empirical research was conducted on a sample of 207 respondents employed in the tertiary level of healthcare. Data analysis included exploratory factor analysis (EFA), confirmatory factor analysis (CFA) and structural equation modelling (SEM). The research results confirmed the existence of all three incentives and indicated that state incentive “training opportunities” has the strongest effect on the motivation of health workers and the sustainability of the healthcare system.

The author of this article explores the question, what is human trafficking. In order to answer this question, definitions of human trafficking are examined, as well as the causes, types of trafficking, recruitment strategies, and the significant problems in conquering human trafficking internationally. Trafficking in human beings affects all regions and most countries of the world. According to official data, Bosnia and Herzegovina is a transit country, but certain reports indicate that it is becoming a country of origin and destination. In order to exemplify the issue of human trafficking on the concrete case study, there is further exploration of how the law of Bosnia and Herzegovina defines it, and how approachs to this problem. Taking into account the increase of human trafficking in the world, especially among countries in transition, it is extremely important to find effective solutions for the prevention of such cross-border criminal activity.

Abstract The name Thymushumifususvar.aureopunctatus, described from Bosnia and Herzegovina, is lectotypified, and its taxonomic value is discussed. Thymusrichardiisubsp.richardii is currently considered an endemic subspecies common to Mallorca (Balearic Islands) and Bosnia and Herzegovina from the Balkan Peninsula. Specimens identified as Th.richardii from both Balearic Islands and Bosnia and Herzegovina were studied to determine if they are indeed the same taxonomic entity. Detailed micromorphological observations and morphometric analysis, suggest that the Balkan plants (Th.humifususvar.aureopunctatus) and the Majorcan populations (Th.richardiisubsp.richardii) are clearly separate entities. For the former name, based on morphological, phytochemical, biogeographical and present results, we propose the subspecific rank, as Th.richardiisubsp.aureopunctatuscomb. & stat. nov. Full descriptions of all five subspecies currently accepted within Th.richardii are provided.

Self-Sovereign Identity (SSI) is a novel and emerging, decentralized digital identity approach that enables entities to control and manage their digital identifiers and associated identity data while enhancing trust, privacy, security, and the many other properties identified and analyzed in this paper. The paper provides an overview and classification of the SSI properties, focusing on an in-depth analysis, furthermore, presenting a comprehensive collection of SSI properties that are important for the implementation of the SSI system. In addition, it explores the general SSI process flow, and highlights the steps in which individual properties are important. After the initial purification and classification phase, we then validated properties among experts in the field of Decentralized and Self-Sovereign Identity Management using an online questionnaire, which resulted in a final set of classified and verified SSI properties. The results can be used for further work on definition and standardization of the SSI field.

In this paper we present details of a virtual tour and game for VR headset that are designed to investigate an interactive and engaging approach of applying VR to student recruitment for an undergraduate course. The VR tour employs a floating menu to navigate through a set of 360° panoramic photographs of the teaching environment and uses hotspot interaction to display further information about the course. The VR game is a fast-paced shooting game. The course information is embedded on cubes that the player needs to focus on and destroy. The game experience is expected to generate an engaging way to promote the course. This work in progress outlines the concept and development of the prototype, and discusses the next stages of testing in order to evaluate the effectiveness of applying VR to undergraduate student recruitment.

Cervical cancer screening is currently based on high-risk human papillomavirus (HR-HPV) molecular testing, Pap cytology testing, and histologic evaluation of cervical biopsies. As primary HPV screening for cervical cancer becomes widely used, some of the recommended screening guidelines propose colposcopy and biopsies following positivity for HPV16/18 without cytologic triage. In such instances, a biopsy would be the only tissue sample available for informing further management. The use of additional histologic levels on cervical biopsies is commonly employed to achieve a diagnosis, although no set criteria for when to obtain additional levels exist. In this study, we evaluated the value of additional sections in cervical biopsy and endocervical curetting, as well as clinical and histologic features that should be considered when ordering additional levels. Additional levels were obtained for the following scenarios: benign mucosa with Pap discrepancy (HSIL or ASC-H interpretation), size discrepancy with the gross description, suspicious atypia for a high-grade lesion, and long-standing high-risk HPV infection. A change in diagnosis was observed in 21.4% of the cases, with an upgrade to a high-grade squamous intraepithelial lesion (CIN2-3) in 12.1% of cases. An initial impression of atypia significantly correlated with both a change in diagnosis and an upgrade to CIN2-3. In the era of primary HPV screening, when evaluating tissue samples following positive HPV test, small, atypical foci should be followed by additional levels. We recommend six (6) initial levels on all cervical biopsies, particularly if there is no loss of tissue between the levels, to ensure an accurate interpretation. This will be crucial in the timely and accurate identification of HPV-related intraepithelial lesions and proper subsequent management.