Many sexting studies conducted in the Western cultures have shown that the percentage is higher in less traditional cultures. However, the generalizability of this phenomenon to non-Western cultures has not been extensively researched. The purpose of this study is to examine and explain cross-cultural differences in sexting behavior among subjects from Bosnia and Herzegovina and Croatia. A mixed methods approach was used. The first, qualitative phase included focus groups with two groups of high school students from Bosnia and Herzegovina and Croatia ( N = 57 ), aged 15 to 19. In the second, quantitative phase, questionnaires were sent to 440 young adults with an average age of 21 years ( SD = 3.8 ). From the interviews with the young people, nonconsensual sexting was perceived as less beneficial. Sexting was viewed as a double standard. The quantitative study revealed gender and country differences in attitudes toward sexting and motives for sexting. Positive attitudes toward sexting were found to predict different forms of sexting motives in both samples. In the sample from Bosnia and Herzegovina, age was found to predict sexting with instrumental motives and body image reinforcement motives. Gender, on the other hand, was found to be predictive of instrumental sexting motives in the Croatian sample and body image reinforcement sexting motives in the Bosnia and Herzegovina sample. This study illustrates the value of cross-cultural approaches combined with mixed methods as a design to study sexting behavior.

Spatial constraints in urban areas very often lead to the application of traffic management measures to meet transport demands. Accordingly, it is very important to identify all potential impacts that could lead to reductions in the street network’s capacity. One such impact is weather conditions. The main motivation of this research is to analyze the impacts of rainfall on one of the most important segments of Belgrade’s street network that represents part of a freeway passing the city center. Our focus is on quantifying the impact of rainfall on speed and capacity. This paper proposes a new approach to analyzing the rainfall impact at the traffic lane level that provides additional possibilities to apply traffic management measures on the traffic lane level instead of at the direction level only. Functional dependences and differences in capacity and speed on traffic lanes were found under the influence of different rainfall intensities. Reductions in free-flow speed depend on the rain category and traffic lanes and vary from 4.5% to 11.58%, while reductions in traffic lane capacity range from 2.46% to 12.97%. We demonstrate the importance of considering the impact of rainfall at the traffic lane level, which could be quality input data for defining appropriate traffic management measures to mitigate the negative impacts.

Decision-making represents a very popular field with many developed approaches. However, still exists the need for the creation of novel integrated models such as well is the case in this paper. The novel integrated Improved Fuzzy Stepwise Weight Assessment Ratio Analysis (IMF SWARA) method, Fuzzy Dombi weighted geometric averaging (FDWGA) operator and PESTEL (P-Political, E-Economic, S-Social, T-Technological, E-Environmental, L-Legal) model has been developed. Five decision-makers (DMs) have evaluated six main elements of the PESTEL analysis and 30 elements more (five for each group). In total, we have created 35 models based on the developed model. Results of PESTEL analysis based on IMF SWARA method and FDWGA shows that legal and economic factors represent the most significant parameters, while last placed belong environmental group. Also, the usefulness of the developed integrated model has been demonstrated.

Choledochal cysts (CCs) are rare congenital anomalies in the form of cystic dilatation of any part of the biliary tree, and they rarely reach the size over 10 cm. We present a case of a 51-year-old female with a one-year history of abdominal pain and palpable mass in the epigastrium and right upper abdomen. Diagnosis of giant CC was made using magnetic resonance cholangiopancreatography. Intraoperatively, a large CC without gallbladder (no previous cholecystectomy was performed) was found under the liver pushing the surrounding structures, extending into the intrapancreatic portion of bile ducts and leading to the destruction of the backside of the pancreas head. Complete excision of CC and biliopancreatic reconstruction was achieved by Roux-en-Y pancreaticojejunostomy and hepaticojejunostomy. This case report describes an extremely rare association between an atypical giant choledochal cyst and gallbladder agenesis.

Uvod: Zdravstveni djelatnici su rizična skupina za HIV-infekciju i imaju ključnu ulogu u prevenciji HIV-a. Cilj: Procijeniti znanje i stavove i korelaciju znanja i stavova zdravstvenih djelatnika o HIV-infekciji. Ispitanici i metode. Ispitanici su zdravstveni djelatnici zaposleni u Domovima zdravlja: Bugojno, Donji i Gornji Vakuf. Upitnik je samostalno izrađen. Stavovi su ispitivani na osnovi modificirane Likertove ljestvice. Procjena znanja i stavova napravljena je tako da više od 50% točnih odgovora ukazuje na dobro znanje i pozitivan stav. Za testiranje statističke značajnosti korišten je χ² test (p <0.05). Za određivanje korelacije varijabli znanje i stavovi korišteni su Pearsonov i Spearmanov koeficijent korelacije. Rezultati: U istraživanju je sudjelovao 81 zdravstveni djelatnik – 57 (70%) žena i 24 (30%) muškarca. Najveći broj ispitanika bile su medicinske sestre (57%), prosječne dobi 36 godina života i 13 godina radnoga staža. Većina ispitanika pokazali su relativno dobro znanje o HIV-infekciji (73%) i pozitivne stavove prema HIV-pozitivnim osobama (80%). Koeficijent korelacije za zbirne vrijednosti znanja i stavova iznosio je 0,336, sa statističkim značajem 0,002. Zaključak: Da bi se poboljšala praksa, smanjila stigma i diskriminacija HIV-pozitivnih osoba u zdravstvenim ustanovama, potrebno je provoditi kontinuiranu edukaciju svih zaposlenika.

[This corrects the article DOI: 10.3389/fvets.2021.688078.].

Abstract Renal cell carcinoma (RCC) occurs in a number of cancer predisposition syndromes, but the genetic architecture of susceptibility to RCC is not well defined. We investigated the frequency of pathogenic and likely pathogenic (P/LP) germline variants in cancer susceptibility genes (CSGs) within a large series of unselected RCC participants. Whole-genome sequencing data on 1336 RCC participants and 5834 controls recruited to the UK 100 000 Genomes Project, a nationwide multicentre study, was analyzed to identify rare P/LP short variants (single nucleotide variants and insertions/deletions ranging from 1 to 50 base pairs) and structural variants in 121 CSGs. Among 1336 RCC participants [mean: 61.3 years (±12 SD), range: 13–88 years; 64% male], 85 participants [6.4%; 95% CI (5.1, 7.8)] had one or more P/LP germline variant in a wider range of CSGs than previously recognized. A further 64 intragenic variants in CSGs previously associated with RCC were classified as a variant of uncertain significance (VUS) (24 ‘hot VUSs’) and were considered to be of potential clinical relevance as further evaluation might results in their reclassification. Most patients with P variants in well-established CSGs known to predispose to renal cell carcinoma (RCC-CSGs) were aged <50 years. Burden test analysis for filtered variants in CSGs demonstrated a significant excess of CHEK2 variants in European RCC participants compared with the healthy European controls (P = 0.0019). Approximately, 6% of the patients with RCC unselected for family history have a germline variant requiring additional follow-up analysis. To improve diagnostic yield, we suggest expanding the panel of RCC-CSGs tested to include CHEK2 and all SDHx subunits and raising the eligibility criteria for age-based testing.

Introduction: With the advent of the COVID-19 pandemic, people’s dietary habits have changed, so the importance of additional supplementation has become a current topic. The aim of this study is to analyze the attitude of female respondents toward dietary supplementation before and during the COVID-19 pandemic.Methods: The research is a cross-sectional study conducted in two different time periods. The sample consisted of two female subsamples who purchased immunity preparations from Verdant Pharmacy before the pandemic (n = 81) and during the pandemic (n = 120). Female respondents in both subsamples were: Of the same age, in the same health condition, residing in the same area (municipality), users of a local pharmacy located near the health center. The research instrument was a non-standardized questionnaire “Assessment of attitudes towards nutritional supplementation,” which consisted of nine questions.Results: During the pandemic COVID-19, the attitude toward the use of preparations to strengthen immunity differs by 7% compared to the pre-pandemic check. The attitude toward the use of preparations to strengthen immunity throughout the year increased by 32.3% (53.3%) during the pandemic, and the attitude toward the choice of preparations to strengthen immunity changed by 13% during the pandemic COVID-19 based on own experience and by 17% based on the recommendation of the pharmacist.Conclusion: The pandemic COVID-19 has contributed to a change in female respondents’ attitudes toward nutritional supplementation to strengthen the immune system during a pandemic. With the help of the media, public health recommendations, and people’s fear of disease, the COVID-19 pandemic led to a change in respondents’ attitudes compared to the pre-pandemic period.

Introduction: Due to the declaration of a state of emergency in the country due to the pandemic COVID-19, the education system was changed to online teaching. The implementation of distance education has led to an increased sedentary lifestyle, decreased physical activity, and increased use of information technologies. The purpose of this study was to analyze the sedentary habits of female students and their physical health during a period of restricted physical activity with reference to online instruction.Methods: The research was conducted among the first to third grade students of Secondary School Konjic, 45 days after the implementation of online instruction. Students of general secondary school (N = 83), business school (N = 68), and medical school (N = 55) completed the questionnaire after their parents gave their consent.Results: The total number of students surveyed was 206, with students from all three schools studied participating in online classes for up to 4 hours. Medical school students spend more than 3 hours completing schoolwork, while students at the other two schools spend up to 2 hours. Statistically significant differences in non-use of information technology during free time exist among medical students (p = 0.00). Female medical students reported daily symptoms such as headaches, reactions to the visual organ (dry eye, redness, and tearing), and pain in the fist area (twitching, cramps, and tingling). Statistically significant differences in the occurrence of pain in the upper back and chest girdle occurred in students of business school (p = 0.00) and general high school (p = 0.00) compared to medical students.Conclusion: Medical students who use information technology the most reported headaches, pain in the fist area, and frequent reactions to the sense of sight (dry eye, lacrimation, and redness). Assuming inappropriate positions during prolonged use of technology may contribute to poor posture.

African Swine Fever virus (ASFV) is a large double-enveloped DNA virus of the Asfarviridae family that causes a lethal hemorrhagic disease in domestic pigs and wild boars. Since 2007, a highly virulent genotype II strain has emerged and spread in Europe and South-East Asia, where millions of animals succumbed to the disease. Field- and laboratory-attenuated strains of ASFV cause highly variable clinical disease severity and survival, and mechanisms remain unclear. We hypothesized that the immunological and hygienic status of pigs is a determinant of ASF disease course. Here we compared the immunological profile at baseline and in response to ASFV infection in specific pathogen-free (SPF) and farm-raised Large White domestic pigs. At steady state, SPF pigs showed lower white blood cell counts and a lower basal inflammatory and antiviral transcriptomic profile compared to farm pigs associated with profound differences in gut microbiome composition. After inoculation with a highly virulent ASFV genotype II strain (Armenia 2008), severe clinical signs, viremia and pro-inflammatory cytokines appeared sooner in SPF pigs, indicating a reduced capacity to control early virus replication. In contrast, during infection with an attenuated field isolate (Estonia 2014), SPF pigs presented a milder and shorter clinical disease with full recovery, whereas farm pigs presented severe protracted disease with 50% lethality. Interestingly, farm pigs showed higher production of inflammatory cytokines, whereas SPF pigs produced more anti-inflammatory IL-1ra early after infection, and presented a stronger expansion of leukocytes in the recovery phase. Altogether, our data indicate that the hygiene-dependent innate immune status has a double-edge sword impact on immune responses in ASF pathogenesis. While the higher baseline innate immune activity helps the host in reducing initial virus replication, it promotes immunopathological cytokine responses, and delays lymphocyte proliferation after infection with an attenuated strain. Such effects should be considered for live vaccine development and vigilance.

Lung transplantation is a therapeutic option for the treatment of advanced lung disease. The risk of pulmonary infections is increased in lung transplant recipients. We report a case of a pulmonary coinfection with Mycobacterium tuberculosis and Nocardia species in a lung transplant recipient.

The paper presents a neuro-fuzzy system for evaluating and predicting the success of a construction company in public tenders. This model enables companies to operate sustainably by assessing their own position in the market. The model was based on data from a seven-year study, where data from the first six years were used to adjust the model, while data from the last year of the study were used for testing and validation. The neuro-fuzzy model was tuned using the Artificial Bee Colony algorithm.

Because for many companies, continuous operation and maintenance of custom software are crucial, they usually want to ensure that this continues even if the software licenser cannot operate in the future, for example, due to bankruptcy. The easiest way to overcome this for the licensee is to get a copy of the updated source code. Software developers are understandably reluctant to give a copy of their proprietary source code to the customer. The most significant asset of software developers is usually their source code, which can contain valuable trade secrets. One of the ways a software developer can deal with a client that requires access to the source code is to agree to store the source code using a triple escrow agreement. Under the escrow source code agreement, the developer provides a copy of the source code and documentation to a neutral party for safekeeping. The third party will hand over the source code to the buyer only after certain conditions defined by the contract have been met, such as the bankruptcy of software developers. That keeps the developer's source code confidential while, in theory, giving the user access to it if necessary. In this paper, we present the term software escrow contract.

Aim of this paper was to examine the contribution of football experience and the self-assessment of tactical/technical skills and social competencies on the perceived self-efficacy in junior and senior football players. A total of 164 football players from Bosnia & Herzegovina have taken part in the research, 79 of which were professional senior players and 85 were professional U18 (junior) players. Three measuring instruments were used in the research: A questionnaire on general information, a self-assessment scale of self-efficacy for football players and a scale for estimating tactical/ technical and social competencies in football was used to gather data. Based on the results and the conducted analyses, it is indicative that the model that encompasses the length of football experience and a self-assessment of tactical/technical and social competencies in senior football players contributed around 8.5% to the total explanation of perceived self-efficacy. In senior players, the length of experience has a greater significance in perceived self-efficacy compared to the perceived success in performing football elements. The set model doesn’t have an equal contribution in junior players, where the model entirely contributed with 14.3% of the explanation of perceived self-efficacy, and the perceived success of performing football elements also has a statistically significant contribution. So, the model which encompasses football experience and the perceived success in performing football elements (tactical/technical and social competencies in football) is not equally predictive in junior and senior players.