The text is a review of the book Ka filozofiji prava kao filozofiji ljudskih prava written by Jasminka Hasanbegović and published by Dosije studio, Belgrade, 2021.

Classification problems have been part of numerous real-life applications in fields of security, medicine, agriculture, and more. Due to the wide range of applications, there is a constant need for more accurate and efficient methods. Besides more efficient and better classification algorithms, the optimal feature set is a significant factor for better classification accuracy. In general, more features can better describe instances, but besides showing differences between instances of different classes, it can also capture many similarities that lead to wrong classification. Determining the optimal feature set can be considered a hard optimization problem for which different metaheuristics, like swarm intelligence algorithms can be used. In this paper, we propose an adaptation of hybridized swarm intelligence (SI) algorithm for feature selection problem. To test the quality of the proposed method, classification was done by k-means algorithm and it was tested on 17 benchmark datasets from the UCI repository. The results are compared to similar approaches from the literature where SI algorithms were used for feature selection, which proves the quality of the proposed hybridized SI method. The proposed method achieved better classification accuracy for 16 datasets. Higher classification accuracy was achieved while simultaneously reducing the number of used features.

Este trabalho irá abordar sobre a criação das rodovias que se mantêm em efeitos ambientais, a fim de inserir qualidade em seu uso e das disposições das faunas que as insere, por vez que se observa os fragmentos que se exercem por decorrência das pressões que sofrem. Por isso, foi abordado os aspectos e maneiras que isso se estrutura, forma essa que sobre os efeitos se dispõe e classifica as contemplações das rodovias. As garantias de requisitos tornam que o surgimento das passagens e o funcionamento contribua na biodiversidade. Como intuito de enfatizar os procedimentos e recursos que se aproveitam nas suas apresentações, distribuindo assim trechos de rodovias ecológicas pelo Brasil. Os impactos fornecem sobre a fauna métodos de diminuir qualquer tipo de acidente em rodovias, em principal pelas mortes de animais que são gerados nos perigos dos trechos. Contudo, se elabora o controle de melhoria, fazendo com que implante instalações seguras que diminua a incidência desses riscos gerados.

The aim of the paper is to investigate the impact of SEO on the business performance of a private university in Sarajevo. Thus, the main research question provides the finding on how does the implementation of SEO influence the performance of the business. Moreover, the tested hypothesis presents whether SEO positively influences the business performance of International Burch University (IBU). The research strategy is to analyze primary data derived from a case study, which is generated following a conversation with the Head of the IBU Marketing and PR team. The data sample is derived from Google Analytics (focusing on the number of visits and sessions, average engagement time, keywords and SERP positioning). Seobility tools are employed in data analysis. Business performance is calculated through the IBU CRM system, focusing on student enrolment. Findings indicate that increasing a site's rankings on search engine results pages (SERPs) led to a variety of positive outcomes for companies including an increase in the number of visitors to the site, an increase in the average amount of time users spent on the site, increased user engagement, and an increase in student enrollment, which resulted in IBU increased annual sales revenue. It will benefit many different groups, including the government, which will benefit in both microeconomic and macroeconomic senses, digital marketing enthusiasts and SEO experts, and the academic world, which will benefit as a framework for future studies and research in the field of SEO recognition and implementation in business queries.

In this work, we present a novel multi-modal trajectory prediction architecture. We decompose the uncertainty of future trajectories along higher-level scene characteristics and lower-level motion characteristics, and model multi-modality along both dimensions separately. The scene uncertainty is captured in a joint manner, where diversity of scene modes is ensured by training multiple separate anchor networks which specialize to different scene realizations. At the same time, each network outputs multiple trajectories that cover smaller deviations given a scene mode, thus capturing motion modes. In addition, we train our architectures with an outlier-robust regression loss function, which offers a trade-off between the outlier-sensitive L2 and outlier-insensitive L1 losses. Our scene anchor model achieves improvements over the state of the art on the INTERACTION dataset, outperforming the StarNet architecture from our previous work.

Abstract Banat Naked Neck is the most important indigenous breed of chickens in Serbia. Marginalized until recently, it is becoming increasingly popular due to its adaptability and good productivity in alternative production systems. However, its history and the current breeding model pose challenges for breed preservation and future improvement. This study aimed to assess the genetic diversity and structure of four subpopulations of Banat Naked Neck from different districts in Serbia (West Backa, North Banat, South Banat and Kolubara) using D-loop mitochondrial DNA sequences and a set of 30 microsatellite markers. Seven haplotypes in the phylogenetic analysis of D-loop mitochondrial DNA suggested maternal origin related to the Indian subcontinent, while haplotype and nucleotide diversity averaged 0.731 ± 0.053 and 0.0067 ± 0.0018, respectively. Microsatellite genotyping showed an average detected number of alleles per locus of 5.129 ± 0.237, while the observed and expected heterozygosity averaged 0.560 ± 0.018 and 0.631 ± 0.014, respectively. Genetic differentiation estimated through FST was 0.051 (p < .001). Two clusters in STRUCTURE analysis showed possible separation of two older subpopulations (South Banat and Kolubara) from the two more recent ones (West Backa and North Banat). This first comprehensive study of genetic diversity serves as the basis for future preservation, use and improvement of the Banat Naked Neck breed.

Uvod: Depresivnost, anksiozonost i stres predstavljaju značajan javnozdravstveni problem kako u svijetu, tako i u Republici Srpskoj. Ovi mentalni poremećaji se učestalije javljaju kod pacijenata oboljelih od hroničnih bolesti. Cilj: Ispitati zastupljenost depresivnosti, anksioznosti i stresa kod oboljelih od hroničnih bolesti (hipertenzija, astma, hronična obstruktivna bolest pluća, dijabetes melitus, maligne bolesti, stanje poslije infarkta miokarda). Ispitati uticaj sociodemografskih faktora (pol, dob, stručna sprema, sadašnji radni status, porodični status) na prevalenciju depresivnosti, anksioznosti i stresa. Ispitati korišćenje anksiolitika za smanjenje prisutnih simptoma. Materijal i metode: Istraživanje je studija presjeka, provedena anketiranjem pacijenata starijih od 18 godina registrovanih u timovima porodične medicine Domu zdravlja Banja Luka u periodu od 1.08.2018. do 1.04.2019. Za procjenu postojanja anksioznosti, depresivnosti i stresa korištena je DASS– 21 skala, sociodemografski podaci su upisivani u samostalno kreiran upitnik. Pacijenti su izabrani iz registra pacijenata sa hroničnim bolestima. Rezultati: Istraživanjem je obuhvaćeno 405 pacijenata oboljelih od hroničnih bolesti. U odnosu na pacijente oboljele od drugih hroničnih bolesti u grupi pacijenata nakon infarkta miokarda statistički značajno najviše je bila izražena depresivnost (p=0.008, 95% CI 8.761-14.412); anksioznost (P= 0.002, 95% CI 19.2444-15.2038) i stres (p=0.016, 95% CI 13.130-18.655). U grupi pacijenata sa hroničnim bolestima 156 (38,5%) pacijenata koristi lijekove za smanjenje tegoba. Zaključak: Rezultati našeg istraživanja su pokazali visok nivo stresa, anksioznosti i depresivnosti kod pacijenata oboljelih od hroničnih bolesti, što upućuje na potrebu preduzimanja mjera za smanjenje stepena ovih mentalnih poremećaja.

The association between urine amylase levels and the development of post-operative complications after Whipple resection is still unknown. The aim of this study was to determine the prognostic value of urine amylase levels for post-operative complications in patients who underwent Whipple resection. In this retrospective-prospective cohort study we analyzed amylase levels in urine, serum, and drains in 52 patients who underwent Whipple resection preoperatively and on Post-operative Day 1 (POD1) after the intervention. Patients were followed up for 3 months to assess their predictive value for post-operative complications. In patients with complications, urine amylase levels were significantly higher on POD1 than before resection (198.89 ± 28.41 vs. 53.70 ± 7.44, p=0.000). Considering the sensitivity and specificity of the urine amylase level on POD1, an area under the ROC curve of 0.918 was obtained (p<0.001, 95% Confidence interval [CI]: 0.894-0.942). Patients with urine amylase levels ≥140.00 U/L had significantly higher risks of post-operative pancreatic fistula (POPF) grade C (definition of POPF done according to the ISGP) (RR:20.26; 95% CI: 1.18-347.07; p=0.038), readmission to hospital (RR: 6.61; 95% CI: 1.53-28.58; p=0.011), reoperation (RR: 5.67; 95% CI: 1.27-25.27; p=0.023), and mortality (RR:17.00; 95% CI: 2.33-123.80; p=0.005) than patients with urine amylase levels <140.00 U/L. Urine amylase levels on POD1 displayed strong and significant positive correlations with serum amylase levels (r=0.92, p=0.001) and amylase levels in drains (r=0.86, p=0.002). We can conclude that urine amylase levels on POD1 have good prognostic value for post-operative complications after Whipple resection and might be used as an additional predictive risk factor.

Due to the SARS-CoV-2 pandemic, the faculties have been met with the task of modifying the traditional teaching environment to remote teaching. During two semesters of remote teaching, the students of the Department of Psychology from the Faculty of Humanities and Social Sciences of University of Mostar have been assessing their skills of using technologies, their motivation for class attendance and assignment completion, as well as their time management skills; they have evaluated the teaching process, reported on technical difficulties and assessed the general satisfaction with the remote teaching process. The results of this research show that students have shown a greater assessment of skills of using technology during the second semester of the remote teaching process, while no difference was established in the level of motivation for class attendance and assignment completion, and no difference was found in time management skills between the two semesters. As far as the satisfaction with remote teaching is concerned, the students marked the teaching process with an average grade of “very good” in both semesters, although the mark “excellent” was given more frequently in the second semester than expected per case. The average grade of satisfaction with the teaching process offers insight into the efficacy of adaption to remote teaching, and also opens up space for further improvement.

Upper esophageal sphincter opening (UESO), and laryngeal vestibule closure (LVC) are two essential kinematic events whose timings are crucial for adequate bolus clearance and airway protection during swallowing. Their temporal characteristics can be quantified through time‐consuming analysis of videofluoroscopic swallow studies (VFSS).

Introduction This article aims at investigating social engagement in the fight against the COVID-19 pandemic in low-resource settings (LRSs). In particular, it focuses on Benin (Sub-Saharan Africa), and reports the results of a field study that investigated the local people's acceptance of the vaccine and the tracking program. Methods This project is the product of a collaboration between the ABSPIE (Applied Biomedical and Signal Processing E-Health) Lab of the University of Warwick (UK) and the LAMA (Laboratoire d'Antropologie Medical Appliqué) of the University of Abomey Calavi (Benin). This international multidisciplinary collaboration brought together engineers, sociologists, anthropologists, and bioethicists. In light of the aims of the project, a qualitative methodology was deemed appropriate. The research team prepared two questionnaires that provided the basis for semi-structured interviews that took place between June and August 2021. Results The research team interviewed 34 Beninese respondents, comprising people aged 60+ (with multiple comorbidities), who were primarily healthcare workers and/or traditional therapists. The results of this work highlight the fact that there is widespread reticence about the vaccination program in Benin, both due to local beliefs and uncertainty about governmental management. In this study, we uncovered several local reasons interfering with the involvement of the population in the vaccination campaign against COVID-19, e.g., the existence of traditional medical practices considered as valid alternatives to vaccines, and many beliefs showing a fear of neo-colonialism hidden in the pandemic threat. Yet, another hindrance can be traced to shortcomings in the management of the vaccination campaign which resulted in obstacles to the implementation of the program. Conclusions This work does not intend to denounce any governmental effort or foster a regressive mindset, but shows how the overall confusion (defined by the World Health Organization as infodemic) linked to the pandemic and its management has caused even more dramatic consequences in LRSs. In addition, the paper proposes a specific framework for the interpretation and management of bioethical and biomedical issues in LRSs that the authors are validating in their current research.

Introduction: Brain MRI scans can predict neurodevelopmental outcomes in neonates treated with therapeutic hypothermia. It is a common clinical practice to perform brain MRI before discharge, but brain MRI scans performed at around four months of age have a better prognostic value for a long-term neurological outcome in asphyxiated neonates. Aim: To identify which of three selected clinical parameters (oral feeding ability, muscle tone, history of seizure) evaluated 10 days after therapeutic hypothermia could predict the primary outcome of an abnormal brain MRI. Methods: We reviewed the medical records of neonates ≥ 36 completed weeks of gestation consecutively treated with therapeutic hypothermia who underwent brain MRI. Clinical parameters on day 10 after therapeutic hypothermia were correlated with brain MRI findings in the first 7-14 days of life. Logic regression analysis was performed using all three covariates of the clinical status, with an abnormal MRI as the primary outcome. Results: Brain MRI was abnormal in 42 (51.85 %) neonates with the following distribution of brain injury patterns: abnormal signal in the basal nuclei in 6, an abnormal signal in the cortex in 16, an abnormal signal both in the cortex and basal nuclei in 20 neonates. Out of three analyzed clinical parameters, feeding difficulty (P < 0.001, OR 8.3, 95% CI 2.9 - 28.9) and a history of seizures (P < 0.001, OR 11.95, 95% CI 3 - 44.5) were significantly associated with an abnormal MRI.  Conclusion: Neonates who were capable of full oral feeding by day 10 after therapeutic hypothermia and had no history of seizures were unlikely to have an abnormal MRI. This may be used in selective planning of pre-discharge MRI in asphyxiated neonates.

Jet quenching is the process of color-charged partons losing energy via interactions with quark-gluon plasma droplets created in heavy-ion collisions. The collective expansion of such droplets is well described by viscous hydrodynamics. Similar evidence of collectivity is consistently observed in smaller collision systems, including pp and p+Pb collisions. In contrast, while jet quenching is observed in Pb+Pb collisions, no evidence has been found in these small systems to date, raising fundamental questions about the nature of the system created in these collisions. The ATLAS experiment at the Large Hadron Collider has measured the yield of charged hadrons correlated with reconstructed jets in 0.36  nb^{-1} of p+Pb and 3.6  pb^{-1} of pp collisions at 5.02 TeV. The yields of charged hadrons with p_{T}^{ch}>0.5  GeV near and opposite in azimuth to jets with p_{T}^{jet}>30 or 60 GeV, and the ratios of these yields between p+Pb and pp collisions, I_{pPb}, are reported. The collision centrality of p+Pb events is categorized by the energy deposited by forward neutrons from the struck nucleus. The I_{pPb} values are consistent with unity within a few percent for hadrons with p_{T}^{ch}>4  GeV at all centralities. These data provide new, strong constraints that preclude almost any parton energy loss in central p+Pb collisions.

The cholecystokinin-2 receptor (CCK2R) is a G protein-coupled receptor (GPCR) that is expressed in peripheral tissues and the central nervous system and constitutes a promising target for drug development in several diseases, such as gastrointestinal cancer. The search for ligands of this receptor over the past years mainly resulted in the discovery of a set of distinct synthetic small molecule chemicals. Here, we carried out a pharmacological screening of cyclotide-containing plant extracts using HEK293 cells transiently-expressing mouse CCK2R, and inositol phosphate (IP1) production as a readout. Our data demonstrated that cyclotide-enriched plant extracts from Oldenlandia affinis, Viola tricolor and Carapichea ipecacuanha activate the CCK2R as measured by the production of IP1. These findings prompted the isolation of a representative cyclotide, namely caripe 11 from C. ipecacuanha for detailed pharmacological analysis. Caripe 11 is a partial agonist of the CCK2R (Emax = 71%) with a moderate potency of 8.5 µM, in comparison to the endogenous full agonist cholecystokinin-8 (CCK-8; EC50 = 11.5 nM). The partial agonism of caripe 11 is further characterized by an increase on basal activity (at low concentrations) and a dextral-shift of the potency of CCK-8 (at higher concentrations) following its co-incubation with the cyclotide. Therefore, cyclotides such as caripe 11 may be explored in the future for the design and development of cyclotide-based ligands or imaging probes targeting the CCK2R and related peptide GPCRs.

Introduction: Burns, depending on the degree of severity, induce a significant pathophysiological response in the body. The complement system participates in the body's defenses as well as in immune responses after burn-induced trauma. Objectives: The main objective of the study was to examine how burn severity affects serum C3 and serum C4 complement values; whether burn severity correlates with serum C3 and C4 complement, and establish the predictive value of the serum C3 complement and serum C4 complement for assessing the severity of the burn.  Patients and methods: According to the degree of TBSA, patients were classified into three groups: group with %TBSA<15% (30 patients), group with %TBSA >15% -25% (30 patients), and group with %TBSA > 25% to 40% (30 patients). According to the depth of burns, patients were classified into two groups partial-thickness burns (39 patients) and full-thickness burns (51 patients). We followed laboratory parameters: value serum C3 complement and serum C4 complement on the first and seventh day after burn trauma. Results: Serum C3 complement was significantly lower in patients with %TBSA>25%-40% and in the group with %TBSA>15%-25% compared to patients with %TBSA<15% on the first and seventh day after burn trauma. Serum C3 complement was significantly lower in patients with %TBSA >15%-25% compared to patients with %TBSA<15% on day one and day seven after burn trauma. Serum complement C4 was not significantly different between burn groups on the first and seventh day. Full-thickness burns have significantly lower levels of serum complement C3, compared to partial-thickness burns, on the 1st and 7th day. Full-thickness burns result in a decrease in serum C4 complement compared to partial-thickness burns on the 7th day after burn trauma, but this decrease is not significant. On the 1st day after burn trauma, we found a negative correlation between %TBSA with serum C3 complement. Serum C4 complement was not correlated with %TBSA on the day 1st. Conclusions: %TBSA and depth of burn result in a significant decrease in serum C3 complement but not serum C4 complement. There is a negative correlation of %TBSA and C3 complement but not serum C4 complement on the 1st day after burn trauma. Serum C3 complement is a significant predictor of burn severity. The predictory significance of the C4 complement is not statistically significant.