Background: Human papillomaviruses (HPV) are one of the most prevalent causes of cervical, anal, and oral cancer, and it is believed that nearly all sexually active males and females have been infected with HPV at some point in their lives. Objective: The purpose of this study is to highlight epidemiological characteristics of the age and genotypical incidence of HPV infection among females in Canton Sarajevo during a 10-year period. Methods: This cross-sectional study was conducted in the period between January 2012 and December 2021 at the medical institutions “Zavod za Ginekologiju, Perinatologiju i Neplodnost “Mehmedbašić“ among females who were admitted for a routine gynaecological exam in Canton Sarajevo in Bosnia and Herzegovina. Results: In total, 1517 patients who reported typical sexarche at 18.35±1.92, having one 721 (47.5%) sexual partner, regular use of contraceptive methods 820 (54.5%) with male condom 513 (62.6%) being the dominant choice of contraception and having gynacological hereditary oncological positive history 141 (9.3%), were included in the study from which 653 (43.05%) patients had positive HPV test and 864 (56.95%) had negative HPV results. HPV positive patients, 386 (59.1%) were infected either with one type of virus only, while 267 (40.9%) patients were infected with multiple virus strains where we have identified 166 virus strain combinations. Analysis showed that the patients infected by only one virus strain were one of next specific HPV viruses: 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66 and 68. HPV-16 was the predominately strain 16 (22.5%) identified among all the patients. Mean age of HPV positive patients was 33.38±7.85, ranging from 18 to 61 years. Conclusion: This study highlights the significance of the most frequent HPV high-risk strains (HPV-16, -18, -31.-33,-45,-52, and -58) among the Bosnia and Herzegovina population as one of the most common cancer-causing strains worldwide.
Background: Restrictive measures implemented by governments around the world to control the coronavirus have an impact on communication, especially the communication of the elderly. Objective: The aim for the article is to determine the attitudes of the elderly towards the ways of communication during the COVID 19 pandemic, and to present the challenges faced by the elderly when using digital ways of communication. The goal is also to point out the importance of providing adequate social support to the elderly. Methods: The sample consisted of 71 respondents from Bosnia and Herzegovina, aged over 60 years, divided into two groups. The questionnaire was used to gather information from respondents on their demographic characteristics as well as to examine participants’ attitudes and confidence regarding the manner and risk of communication associated with COVID-19. Results and Discussion: The results of this research showed that the elderly are actively using digital technologies, but that they are largely dissatisfied with their skills in using digital technologies. Most of the information during the COVID 19 pandemic is given to elderly people via television and telephone (video) conversations with family members and friends. 57.7% of the elderly stated that they greatly lacked direct communication, and it turned out that people living in elderly homes were in a slightly more favorable position. As many as 4/5 of the respondents reported feelings of anxiety, fear, loneliness, and depression. Conclusion: The older part of the population (those over 60 years old), especially in developing countries, including Bosnia and Herzegovina, is facing the challenge of “digitization of communication“. In the context of the COVID-19 pandemic, the elderly are “calling“ for special support and the provision of training and access to technological resources in order to reduce negative psychological consequences and go one step further in creating an “elder-friendly” society.
InxGa1−x N is a strategically important material for electronic devices given its tunable bandgap, modulated by the In/Ga ratio. However, current applications are hindered by defects caused by strain relaxation and phase separation in the material. Here, we demonstrate growth of homogeneous InxGa1−x N films with 0.3 < x < 0.8 up to ∼30 nm using atomic layer deposition (ALD) with a supercycle approach, switching between InN and GaN deposition. The composition is uniform along and across the films, without signs of In segregation. The InxGa1−x N films show higher In-content than the value predicted by the supercycle model. A more pronounced reduction of GPCInN than GPCGaN during the growth processes of InN and GaN bilayers is concluded based on our analysis. The intermixing between InN and GaN bilayers is suggested to explain the enhanced overall In-content. Our results show the advantage of ALD to prepare high-quality InxGa1−x N films, particularly with high In-content, which is difficult to achieve with other growth methods.
The development of material production technology has led to the application of new materials in construction. Because concrete is currently the most commonly used construction material, which in addition to numerous advantages (water resistance, low maintenance costs, easy workability, low cost, etc.) also has certain disadvan- tages (low tensile strength and brittle fracture behavior). Reinforcement of concrete using discrete fibers, ran- domly distributed, is an acceptable solution for improving the ductility of concrete. Carbon fiber reinforcement (CFRP) has been widely studied in the last two decades, as it represents a suitable alternative for the reinforce- ment of existing (endangered) RC structures. The advantages of this material are reflected in the relatively simple application, increased performance of the RC structure, low weight of the elements, etc. The paper also analyzes the existing cases of application of this material, as well as the presentation of previous research in the field of structural reinforcement using carbon fibers. Key words: Carbon fiber, Carbon fiber-reinforced polymer (CFRP), reinforcement concrete structures, reinfor- cement of existing structures, structural behavior of construCTIONS
Brown coal mining conducted at greater depths, characterised with severe mining-geological conditions often results in deviation from the applied mining methods. Experiences gained in mechanised longwall mining of roof plate in deeper parts of Raspotočje mine, using method of roof caving without safety pillars left behind the working panels indicates to shortcomings of the applying mining method. Frequent occurences of spontaneous mine fires, of hazardous gasses well above the limit values, and constant exposure to rock bursts of various in- tensity resulted in application of three longwall face ventilation regimes: conventional „U“ ventilation system, ventilation with gas channel and middle hallway, and separate ventilation of the upper part of the longwall face. This paper presents experience based information gained in a five years period of mining, analysed using one- factor and two factor regression analyses applied to a number of technical-technological parameters (ventilation, mining system, etc) influencing occurences of spontaneous mine fires and increased gas release in various ventilation regimes at longwall face aimed to give basic guidelines for minimisation and elimination of certain hazards. Keywords: ventilation regime, spontaneous fires, gas release, mechanised longwall.
In the present-day environment pertaining to digitalisation, increasing competition on the market and changes in industries, the CRM as a system is an essential tool for success. The issue of CRM system application in higher education institutions is insufficiently researched, especially in the parts that should indicate a clear connection between participants in higher education and CRM in higher education institutions, and factors that decision makers should pay attention to when making decisions about CRM implementation. Therefore, the aim of the paper is to research the functionality, application and advantages of CRM in the higher education sector, and to determine the features that will facilitate effective decision-making on the implementation of CRM. As a result of the research, a proposal for a conceptual model/framework of CRM was presented. The proposal is presented for the purpose of making appropriate decisions for higher education institutions when it comes to developing their own or purchasing a ready-made CRM solution. From the scientific aspect, the paper contributes to the existing literature by providing decision makers with an insight into the structure of the CRM system, its elements, connections and functionalities, as well as a description of the model with the information they need to pay attention to when making decisions.
This study analyzed 16 bisphenols (BPs) in wastewater and sludge samples collected from different stages at a municipal wastewater treatment plant based on sequencing batch reactor technology. It also describes developing an analytical method for determining BPs in the solid phase of activated sludge based on solid-phase extraction and gas chromatography-mass spectrometry. Obtained concentrations are converted into mass flows, and the biodegradation of BPs and adsorption to primary and secondary sludge are determined. Ten of the sixteen BPs were present in the influent with concentrations up to 434 ng L−1 (BPS). Only five BPs with concentrations up to 79 ng L−1 (BPA) were determined in the plant effluent, accounting for 8 % of the total BPs determined in the influent. Eleven per cent of the total BPs were adsorbed on primary and secondary sludge. Overall, BPs biodegradation efficiency was 81%. The highest daily emissions via effluent release (1.48 g day−1) and sludge disposal (4.63 g day−1) were for BPA, while total emissions reached 2 g day−1 via effluent and 6 g day−1 via sludge disposal. The data show that the concentrations of BPs in sludge are not negligible, and their environmental emissions should be monitored and further studied.
In the present study, vortex-assisted matrix solid-phase dispersion (VA-MSPD) extraction was used to isolate the major bioactive compounds from H. arenarium. To reduce the negative environmental impact of the conventionally used organic solvents, four different choline chloride-based natural deep eutectic solvents (NADES) were investigated as possible eluents. The most influential VA-MSPD extraction parameters: stationary phase (adsorbent), adsorbent/sample ratio, vortex time, and volume of extraction solvent were systematically optimized. Ultrasound-assisted extraction with 80% MeOH was used as the standard method for the comparison of results. The stability of the obtained extracts was studied over a period of 0 to 60 days at three different temperatures (−18 °C, 4 °C, and 25 °C). All extracts were evaluated both spectrophotometrically (determination of total phenolic content (TPC) and antioxidant activity by ABTS and FRAP assay) and chromatographically (HPLC-UV). NADES based on choline chloride and lactic acid (ChCl-LA) was selected as the most effective extractant, with a determined TPC value of its extract of 38.34 ± 0.09 mg GA/g DW (27% higher than the methanolic VA-MSPD extract) and high antioxidant activity. The content of individual phenolic compounds (chlorogenic acid, dicaffeoylquinic acid isomers, naringenin isomers, and chalcones) in the ChCl-LA extract, determined by HPLC-UV, was comparable to that of the conventionally obtained one. Moreover, the stabilization effect of ChCl-LA was confirmed for the studied compounds: chlorogenic acid, naringenin-4′-O-glucoside, tomoroside A, naringenin-5-O-glucoside, isosalipurposide, and naringenin. The optimum VA-MSPD conditions for the extraction of H. arenarium polyphenols were: florisil/sample ratio of 0.5/1, a vortex time of 2 min, and an elution volume of ChCl-LA of 10 mL.
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