BACKGROUND Non-ST segment elevation myocardial infarction (NSTEMI) poses significant challenges in clinical management due to its diverse outcomes. Understanding the prognostic role of hematological parameters and derived ratios in NSTEMI patients could aid in risk stratification and improve patient care. AIM To evaluate the predictive value of hemogram-derived ratios for major adverse cardiovascular events (MACE) in NSTEMI patients, potentially improving clinical outcomes. METHODS A prospective, observational cohort study was conducted in 2021 at the Internal Medicine Clinic of the University Hospital in Tuzla, Bosnia and Herzegovina. The study included 170 patients with NSTEMI, who were divided into a group with MACE and a control group without MACE. Furthermore, the MACE group was subdivided into lethal and non-lethal groups for prognostic analysis. Alongside hematological parameters, an additional 13 hematological-derived ratios (HDRs) were monitored, and their prognostic role was investigated. RESULTS Hematological parameters did not significantly differ between non-ST segment elevation myocardial infarction (NSTEMI) patients with MACE and a control group at T1 and T2. However, significant disparities emerged in HDRs among NSTEMI patients with lethal and non-lethal outcomes post-MACE. Notably, neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) were elevated in lethal outcomes. Furthermore, C-reactive protein-to-lymphocyte ratio (CRP/Ly) at T1 (> 4.737) demonstrated predictive value [odds ratio (OR): 3.690, P = 0.024]. Both NLR at T1 (> 4.076) and T2 (> 4.667) emerged as significant predictors, with NLR at T2 exhibiting the highest diagnostic performance, as indicated by an area under the curve of 0.811 (95%CI: 0.727-0.859) and OR of 4.915 (95%CI: 1.917-12.602, P = 0.001), emphasizing its important role as a prognostic marker. CONCLUSION This study highlights the significant prognostic value of hemogram-derived indexes in predicting MACE among NSTEMI patients. During follow-up, NLR, PLR, and CRP/Ly offer important insights into the inflammatory processes underlying cardiovascular events.

Abstract Dietary acrylamide exposure potentially poses health risks, including increased cancer risk and neurotoxic effects. There is no official data on acrylamide levels in food products on the Bosnia and Herzegovina (B&H) market, making it challenging to assess the associated health risks. As a non-EU country, B&H lacks national regulations aligned with Commission Regulation (EU) 2017/2158, which establishes benchmark levels and mitigation measures for acrylamide. This study used GC-MS to assess acrylamide content in fifteen food products from the B&H market, categorised as potato crisps/sticks, biscuits/wafers, and coffee. Acrylamide levels in some potato crisps and sticks, tea rings, and plain biscuits exceeded benchmark values, while levels in butter biscuits, biscuits with inclusions, filling or coating, wafers, and instant coffee, remained within acceptable limits. The highest acrylamide level was in potato sticks (1048.3 μg/kg), and the lowest in butter biscuits (23.8 μg/kg). Potato crisps/sticks had the highest average acrylamide levels (677.5 μg/kg), followed by tea rings and plain biscuits (444.5 μg/kg). Potato-based snacks accounted for the highest estimated dietary acrylamide intake. Most products exceeding benchmark levels originated from B&H, suggesting local producers might not fully apply mitigation strategies. These findings emphasise the need for regulatory reform, regular market monitoring, and targeted mitigation efforts.

The Internet and digital platforms are often portrayed as public spaces, hosting both private conversations and discussions of public interest. Political campaigns are conducted and business transactions are also carried out there. This paper challenges this view by highlighting the differences between the Internet and traditional public places. Instead, it argues that the Internet increasingly resembles a mosaic of private domains controlled by a few powerful entities that dictate the flow of information. This paper examines the issue from the perspective of the benefits that public places provide in modern democratic societies and posits the debate within Habermas’s understanding of the public sphere, providing for differences in how public place is typically perceived regarding the Internet and especially digital platforms. Finally, it outlines the ongoing legislative debate in Bosnia and Herzegovina on this issue, with comparative insights from the legal frameworks of Serbia and Croatia.

The ECFA Higgs, electroweak, and top Factory Study ran between 2021 and 2025 as a broad effort across the experimental and theoretical particle physics communities, bringing together participants from many different proposed future collider projects. Activities across three main working groups advanced the joint development of tools and analysis techniques, fostered new considerations of detector design and optimisation, and led to a new set of studies resulting in improved projected sensitivities across a wide physics programme. This report demonstrates the significant expansion in the state-of-the-art understanding of the physics potential of future e+e- Higgs, electroweak, and top factories, and has been submitted as input to the 2025 European Strategy for Particle Physics Update.

Obična lavanda (Lavandula angustifolia Miller) je niska, višegodišnja grmasta biljka koja raste u zemljama oko zapadnog Mediterana. Potekla je iz sunčanih stjenovitih područja i prvenstveno se uzgaja zbog svojih esencijalnih ulja. Različite studije pokazale su da određene vrste ljekovitih biljaka, kao što je L. angustifolia Miller, koje sadrže linalol i linalil acetat ester, imaju blagi sedativni učinak i koriste se u aromaterapiji i fitoterapiji za ublažavanje stresa. Svrha ove studije je utvrditi antioksidacijsku aktivnost uzoraka obične lavande. Uzorci biljnog materijala prikupljeni su sa sljedećih područja: Gubavica (općina Mostar) i Šehovina (grad Mostar). Pri tome su analizirana četiri uzorka: esencijalno ulje dobiveno hidrodestilacijom biljnog materijala (Gubavica), uzorak maceriran u etil acetatu (Šehovina), prikupljeni vodeni ostatak nakon hidrodestilacije (Gubavica) te komercijalno esencijalno ulje. Određivanje antioksidacijske aktivnosti uzoraka provedeno je s pomoću sljedećih metoda: DPPH, ABTS i FRAP. Hidrodestilirano esencijalno ulje, kao i komercijalno ulje, pokazali su slabiju antioksidacijsku aktivnost, što je potvrđeno svim korištenim metodama. Slabija antioksidacijska aktivnost također je zabilježena u analizi uzorka etil acetata. Praćenjem tijeka reakcije za navedene uzorke nije bilo moguće izračunati IC50 vrijednost. Vodeni ostatak nakon hidrodestilacije pokazao je najvišu antioksidacijsku aktivnost prema svim korištenim metodama, što je potvrđeno IC50 vrijednošću prema DPPH metodi, koja je bila 0,032 ± 0,006 mg/mL, dok je za ABTS metodu IC50 vrijednost bila 0,135 ± 0,003 mg/mL. Također, prema FRAP metodi, vodeni ostatak nakon hidrodestilacije pokazao je najbolju antioksidacijsku aktivnost (1099,45 ± 25,39 mg Evit. C/g ekstrakta). Usporedbom kemijskog sastava i antioksidacijske aktivnosti ispitivanih uzoraka može se zaključiti da su za antioksidacijsko djelovanje odgovorni fenolni spojevi koji su bili sadržani u vodenom ostatku nakon hidrodestilacije esencijalnog ulja, koji je i pokazao najbolju aktivnost, a da spojevi koji čine esencijalno ulje imaju neznatnu učinkovitost kad je u pitanju određivanje antioksidacijskog kapaciteta.

The ECFA Higgs, electroweak, and top Factory Study ran between 2021 and 2025 as a broad effort across the experimental and theoretical particle physics communities, bringing together participants from many different proposed future collider projects. Activities across three main working groups advanced the joint development of tools and analysis techniques, fostered new considerations of detector design and optimisation, and led to a new set of studies resulting in improved projected sensitivities across a wide physics programme. This report demonstrates the significant expansion in the state-of-the-art understanding of the physics potential of future e+e- Higgs, electroweak, and top factories, and has been submitted as input to the 2025 European Strategy for Particle Physics Update.

Context: Anomaly detection is crucial for maintaining cloud-based software systems, as it enables early identification and resolution of unexpected failures. Given rapid and significant advances in the anomaly detection domain and the complexity of its industrial implementation, an overview of techniques that utilize real-world operational data is needed. Aim: This study aims to complement existing research with an extensive catalog of the techniques and monitoring data used for detecting anomalies affecting the performance or reliability of cloud-based software systems that have been developed and/or evaluated in a real-world context. Method: We perform a systematic mapping study to examine the literature on anomaly detection in cloud-based systems, particularly focusing on the usage of real-world monitoring data, with the aim of identifying key data categories, tools, data preprocessing, and anomaly detection techniques. Results: Based on a review of 104 papers, we categorize monitoring data by structure, types, and origins and the tools used for data collection and processing. We offer a comprehensive overview of data preprocessing and anomaly detection techniques mapped to different data categories. Our findings highlight practical challenges and considerations in applying these techniques in real-world cloud environments. Conclusion: The findings help practitioners and researchers identify relevant data categories and select appropriate data preprocessing and anomaly detection techniques for their specific operational environments, which is important for improving the reliability and performance of cloud-based systems.

English has assumed the role of a global business lingua franca (BELF) at the turn of the 21st century, with an ever-increasing number of multinational corporations (MNCs) adopting English as either their official corporate language, or, the working language as a natural byproduct of a company’s linguascape. This paper investigates the use of English in a business context drawing from the BELF paradigm, i.e. it sets out to compare and contrast the frontstage and backstage English in a multinational organization in written (email) communication, as an answer to a call by Kankaanranta et al. (2018), as this specific kind of study within this genre is still underrepresented and under-researched within the Global South setting. The emails used in this study were collected from a small-sized Turkish-Bosnian international company based in B&H with a total of 10 employees. The approach adopted for the analysis of the study is discourse-analytical in its essence, supported by corpus analysis instruments. The analysis showed that the backstage English, primarily used among employees for internal communication, is indeed in most cases characterized by BELF features. Conversely, frontstage English, was shown to be aligned more closely with native English norms due to its role in corporate branding and external communication, although showing some variability as well. It is expected that the results of the study will help in understanding English communication nuances within this particular business context and help businesses foster clearer, more effective interactions across linguistic and cultural boundaries.

This study investigates the influence of specific surface area (SSA) and aluminum hydroxide particle size on sodium aluminate’s purification efficiency in the Bayer process. This research examines how variations in SSA affect the adsorption and incorporation of contaminants such as Cu, Fe, and Zn, as well as the optimal balance between effective purification and excessive Al2O3 loss. Different SSA values and purification durations are analyzed to optimize the purification process and determine conditions that maximize impurity removal while maintaining system stability. Additionally, solid residue characterization using X-ray diffraction (XRD), scanning electron microscopy (SEM), and energy-dispersive spectroscopy (EDS) provides insights into impurity incorporation mechanisms, including isomorphic replacement, surface adsorption, and co-crystallization. This study highlights key process parameters that influence impurity behavior and crystallization dynamics, offering valuable guidance for refining industrial purification strategies and improving aluminum hydroxide quality.

Abstract Background Humans spend up to 90% of their time indoors and are exposed to a significant number of microbes in their homes, which can have important implications for their health. Aim This study focused on analysing the influence of environmental factors on microbiome diversity and abundance in bed dust and linking the exposure to dust bacteria with asthma. Subjects and methods A total of 90 dust samples were collected from homes of asthmatic patients (n = 59) and controls (n = 31) aged 5–18 years. The bacterial fraction of the microbiome was analysed using 16S rRNA gene high-throughput sequencing on the Illumina MiSeq platform and downstream analyses in QIIME2 and R. Microbiome profiles were associated with asthma and relevant environmental and household data. Results Higher bacterial β-diversity in the environment was shown to be inversely associated with asthma (p = 0.009). Also, living environment (p = 0.002), housing type (p = 0.004), presence of pets in the household (p = 0.001), and cleaning practices (p = 0.006 for dusting and p = 0.011 for vacuuming) were prominent environmental factors affecting the bed dust microbiome. Conclusion Our results suggest significant differences in bacterial community composition between individuals with and without asthma and the interaction between indoor microbiome and asthma is mediated by environmental factors in the household.

Accurate channel estimation is critical for high-performance Orthogonal Frequency-Division Multiplexing systems such as 5G New Radio, particularly under low signal-to-noise ratio and stringent latency constraints. This letter presents HELENA, a compact deep learning model that combines a lightweight convolutional backbone with two efficient attention mechanisms: patch-wise multi-head self-attention for capturing global dependencies and a squeeze-and-excitation block for local feature refinement. Compared to CEViT, a state-of-the-art vision transformer-based estimator, HELENA reduces inference time by 45.0\% (0.175\,ms vs.\ 0.318\,ms), achieves comparable accuracy ($-16.78$\,dB vs.\ $-17.30$\,dB), and requires $8\times$ fewer parameters (0.11M vs.\ 0.88M), demonstrating its suitability for low-latency, real-time deployment.