The starting point of this paper is that science and religion, alongside social and political dynamics, have massive effects on global challenges such as conflicts (national, geopolitical, ideological, or religious), environmental matters, growing radicalism, nationalism, or influence social justice. Historically, the relationship between science and religion has recently ranged from conflict to hostility. The normative action of mutual understanding and the interaction and cooperation between science and religion depend primarily on the participants (non-politized theologians and scientists), in constructive dialogue, particularly regarding global issues. Conflicting narratives between science and religion is an opportunity for joint learning and contribution to a better world and a compassionate culture. Therefore, the leading ideas of the discourse across borders are the promotion of synergy between sciences and religions, as well as cooperation between nations in promoting a compassionate society – an empathetic civilization. Nonviolent dissent to global challenges should be involved in changing the power imbalance as a source of structural violence, but the practice of liberation must focus on social justice, sociopolitical stability, and critical human security. In facing global challenges, science and religion must have diplomatic value by promoting mutual understanding and using a common language through collaboration. Religious traditions, and science, strengthened by global non-religious spiritualism as the valuable means of general spiritual growth, should assert a culture of peace and dialogue for transnational challenges. However, material science and theology are not explicitly formative to growing radical nationalism, racism, conflicts, hegemonism, destruction of the earth, and socioeconomic inequality. The healthy strategic union between science and religion enforced by ethical and constructive politics can support and enhance the resolution of global issues and antagonistic practices. Such a normative-formative framework should ensure that knowledge is developed to advance human, social, economic, and environmental goals according to the moral principles of each religion.
Objective: Advanced proliferative diabetic retinopathy can lead to serious ophthalmological complications, including blindness. This research aimed to determine visual outcomes after pars plana vitrectomy secondary to proliferative diabetic retinopathy, as well as to identify its predictors. Methods: This prospective clinical study was performed in the Ophthalmology Clinic of the Clinical Centre University of Sarajevo. 60 subjects (eyes) with performed pars plana vitrectomy secondary to proliferative diabetic retinopathy were included in the study. Results: After univariate linear regression analysis, glucose, HbA1c, vascular endothelial growth factor, previous pan-retinal laser photocoagulation, baseline best corrected visual acuity, gas injection, vitreous haemorrhage, iris rubeosis, and glaucoma were found to be statistically significant parameters associated with postoperative visual outcome (p<0.05). Multivariate linear regression analysis was performed to evaluate the association between factors and postoperative best corrected visual acuity. Only intravitreal vascular endothelial growth factor concentration, previous pan-retinal photocoagulation, and gas injection remained statistically significant associated with postoperative best corrected visual acuity (p<0.05). Conclusion: Vitrectomy is an effective treatment for advanced proliferative diabetic retinopathy. Factors correlated with the better visual outcome are good systemic control, previous pan-retinal photocoagulation, low intravitreal vascular endothelial growth factor concentration, younger age, intraoperative internal gas tamponade, combined phacoemulsification and pars plana vitrectomy surgery, and the absence of postoperative complications. Abbreviations: PDR = proliferative diabetic retinopathy, VEGF = vascular endothelial growth factor, TDR = tractional retinal detachment, BCVA = best corrected visual acuity, DR = diabetic retinopathy, RDD = rhegmatogenous retinal detachment, NVG = neovascular glaucoma, BRVO = branch retinal vein occlusion, CBC = complete blood count, DBT = differential blood count, ESR = erythrocyte sedimentation rate, HbA1c = glycosylated hemoglobin, PHACO = phacoemulsification, ILM = internal limiting membrane, PPV = pars plana vitrectomy, IOP = intraocular pressure, PRP = pan-retinal photocoagulation, ETDRS = Early treatment diabetic retinopathy study
The CVAE is one of the most widely-used models in trajectory prediction for AD. It captures the interplay between a driving context and its ground-truth future into a probabilistic latent space and uses it to produce predictions. In this paper, we challenge key components of the CVAE. We leverage recent advances in the space of the VAE, the foundation of the CVAE, which show that a simple change in the sampling procedure can greatly benefit performance. We find that unscented sampling, which draws samples from any learned distribution in a deterministic manner, can naturally be better suited to trajectory prediction than potentially dangerous random sampling. We go further and offer additional improvements including a more structured Gaussian mixture latent space, as well as a novel, potentially more expressive way to do inference with CVAEs. We show wide applicability of our models by evaluating them on the INTERACTION prediction dataset, outperforming the state of the art, as well as at the task of image modeling on the CelebA dataset, outperforming the baseline vanilla CVAE. Code is available at https://github.com/boschresearch/cuae-prediction.
Psychological care involves caring for the patient's psychological needs using a range of skills such as listening, perceiving, communicating, and empathizing, with the ultimate res of alleviating human suffering. The nurse spends the most time with the psychiatric patient; she is with the patient from his admission to the hospital, during his stay, until he leaves the hospital. Observing the patient's behavior, she determines problems in health care. In order for a nurse to solve this problem, she must be educated, experienced in her professional vocation, and have a good knowledge of the healthcare process, because that is the only way she can make an appropriate plan and choose the most appropriate interventions. In addition to knowing the process of health care, a nurse must also be extremely patient and possess certain communication skills due to the nature of the illnesses of patients suffering from psychiatric disorders. Therapeutic communication is actually the core and essence of all interactions between a nurse and a patient. It is often stated that it is the nurse who takes care of the psychiatric patient and who has the most face-to-face contact with patients. The nurse deals with the total personality of the psychiatric patient, and therefore she applies models that make the assessment of the patient's needs the basis of health care. The main goal of this scientific review is to investigate and analyze the role of psychiatric nursing as an indispensable element in nursing practice, explore its importance for improving the quality of health care and patient well-being, and provide guidelines for the integration of psychiatric nursing in nursing practice.
Newer research points to alterations in the plasma redox status and the HDL subclass distributions in cancer. We aimed to assess the redox status and the HDL subclass distributions, lipids, and inflammatory markers in lymphoma patients in order to determine whether they were correlated with changes in FDG-PET/CT scans. At the beginning of this study, redox status, HDL subclasses, lipids, and inflammation biomarkers were determined in 58 patients with lymphoma (Hodgkin lymphoma, n=11 and non-Hodgkin lymphoma, n=47), and these same measurements were reassessed during their ensuing treatment (in 25 patients). Initially, the total oxidation status (TOS), the prooxidant–antioxidant balance (PAB), the OS index (OSI), the total protein sulfhydryl groups (SH-groups), and the advanced oxidation protein products (AOPP) were significantly higher in lymphoma patients as compared to healthy subjects, but the total antioxidant status (TAS) was significantly reduced. The PAB had a strong correlation with the CRP and interleukin-6 (rho=0.726, p<0.001; rho=0.386, p=0.003). The correlations between these parameters and the maximum standardized uptake values (SUVmax) were: PAB, rho=0.335 and p=0.010; SH-groups, rho=0.265 and p=0.044; CRP, rho=0.391 and p=0.002; HDL3b, rho=0.283 and p=0.031; HDL2b, rho= -0.294 and p=0.025; and HDL size, rho= -0.295 and p=0.024. The reductions in SUVmax between two follow-up points were associated with increases in the OSI, TOS, and SH-groups, as well as a reduction in the PAB and TAS. In conclusion, the redox parameters in patients with lymphoma were consistent with FDG-PET/CT findings. Targeting the redox status parameters and the HDL subclasses could be potential strategies in the molecular fight against lymphoma.
This paper discusses a low-voltage ride-through (LVRT) method for high-voltage direct current (HVDC) transmission systems that serve as an interconnector between the main onshore ac grid and an islanded offshore ac load. When a line-to-ground fault occurs in the onshore ac grid, a voltage sag will be applied to the HVDC transmission system. This sag will cause fluctuations of the dc voltage, which will cause a shutdown of the entire HVDC system. The proposed LVRT method stabilizes the dc voltage of the HVDC transmission line by reducing the amplitude of the voltage of the offshore ac grid, which is kept constant during normal operation. The proposed method allows the HVDC system to remain connected during voltage sags in the onshore ac grid and enables faster transmission recovery after fault clearance. The validity of the proposed LVRT method is verified by simulations.
The current stage of the country development is characterized by increasing the role of universities not only in the educational and public space of the country, but also in the socio-economic advancement of cities and regions. Universities forming the educational potential of the cities are flagships of their technological transformation, form the city brand, increase their sustainability, lifeabitity and competitiveness. The aim of the study is the typologization of cities – university centers of Russia, carried out with the help of a comprehensive index of educational potential developed by the authors. The statistical base for assessing the educational potential of cities was the data of the Monitoring of the effectiveness of the educational institutions of higher education in 2022, university rankings of the British company Quacquarelli Symonds (integral QS ranking and 5 integrated areas of study), RA-Expert (integrated and individual in 29 areas of study), the Three Missions of the University rating, and the University Reputation Ranking.The study was carried in 3 stages, each of them involved special methodological approaches. At the first stage, there was a review of existing theoretical and practical research on the subject, the integrated index of the educational potential of university centers was developed. At the second stage of the study on the bases of this index a typology of university centers of the Russian Federation was carried out. At the third stage, there was a comparation of the previous results with their positions in the Sustainable Urban Development Index and realization of creative potential. The implementation of educational potential of the most sustainable competitive university centers was separately analyzed in the context of the strategy of internationalization and export of education.National project “Science and Universities” aimed at formation of 100 universities as centers of scientific, technological and socio-economic development by 2030, as well as the program for the construction of 25 world-level modern campuses increase attention to cities as centers of localization of higher education, their educational potential, and, ultimately, their competitiveness.The scientific importance of the research is the development of methodological approaches to assessing the educational potential of cities – university centers and its testing on the example of 1208 universities located in 306 cities of 84 regions of Russia. As a result, a typology of Russian university centers was carried out according to the level of educational potential: 6 types of cities were identified, differing in the city-forming role of higher educational institutions, their role in brand formation and the competitiveness of the city.The typology makes it possible to assess the educational potential of university centers in Russia to form effective strategies for their development in the context of the realizing the national development goals of Russia.
Abstract Background The European Society of Plastic, Reconstructive and Aesthetic Surgery (ESPRAS) comprises 40 national societies across Europe. In addition to ESPRAS, there are 8 different European Plastic Surgery societies representing Plastic Surgeons in Europe. The 4 th European Leadership Forum (ELF) of ESPRAS, held under the motto “Stronger together in Europe” in Munich in 2023, aimed to collect and disseminate information regarding the national member societies of ESPRAS and European societies for Plastic Surgeons. The purpose was to identify synergies and redundancies and promote improved cooperation and exchange to enhance coordinated decision-making at the European level. Material and methods An online survey was conducted regarding the organisational structures, objectives and challenges of national and European societies for Plastic Surgeons in Europe. This survey was distributed to official representatives (Presidents, Vice Presidents and General Secretaries) and delegates of national and European societies at the ELF meeting. Missing information was completed using data obtained from the official websites of the respective European societies. Preliminary results were discussed during the 4 th ELF meeting in Munich in March 2023. Results The ESPRAS survey included 22 national and 9 European Plastic Surgery societies representing more than 7000 Plastic Surgeons in Europe. Most national societies consist of less than 500 full members (median 182 members (interquartile range (IQR) 54–400); n=22). European societies, which covered the full spectrum or subspecialities, differed in membership types and congress cycles, with some requiring applications by individuals and others including national societies. The main purposes of the societies include research, representation against other disciplines, specialisation and education as well as more individual goals like patient care and policy regulation. Conclusion This ESPRAS survey offers key insights into the structures, requirements and challenges of national and European societies for Plastic Surgeons, highlighting the relevance of ongoing close exchange between the societies to foster professional advancement and reduce redundancies. Future efforts of the ELF will continue to further explore strategies for enhancing collaboration and harmonisation within the European Plastic Surgery landscape.
The influence of process parameters in the three-stage purification of aluminate solution from the Bayer process and aluminum hydroxide was considered in this paper. One of the ways of purification is treating the aluminate solution in order to reduce the concentrations in the starting raw material (solution) and then treating the aluminum hydroxide at a certain temperature and time in order to obtain an alumina precursor of adequate quality. The purification process itself is divided into three phases. The first phase involves the treatment of sodium aluminate with lime in order to primarily remove Ca2+ and (SiO3)2− impurities. Phase II aims to remove impurities of Zn2+, Fe2+, and Cu2+ by treatment with controlled precipitation using specially prepared crystallization centers. In Phase III, Na+ is removed by the process of hydrothermal washing of Al2O3 ∙ 3H2O. In this work, parameters such as temperature (T), reaction time (t), and concentration of lime (c) were studied in order to remove the mentioned impurities and obtain the purest possible product that would be an adequate precursor for special types of alumina.
Mycotoxins present a significant health concern within the animal-feed industry, with profound implications for the pig-farming sector. The objective of this study was to evaluate the efficacy of two commercial adsorbents, an organically modified clinoptilolite (OMC) and a multicomponent mycotoxin detoxifying agent (MMDA), to ameliorate the combined adverse effects of dietary aflatoxins (AFs: sum of AFB1, AFB2, AFG1, and AFG2), fumonisins (FBs), and zearalenone (ZEN) at levels of nearly 0.5, 1.0, and 1.0 mg/kg, on a cohort of cross-bred female pigs (N = 24). Pigs were randomly allocated into six experimental groups (control, mycotoxins (MTX) alone, MTX + OMC 1.5 kg/ton, MTX + OMC 3.0 kg/ton, MTX + MMDA 1.5 kg/ton, and MTX + MMDA 3.0 kg/ton), each consisting of four individuals, and subjected to a dietary regimen spanning 42 days. The administration of combined AFs, FBs, and ZEN reduced the body-weight gain and increased the relative weight of the liver, while there was no negative influence observed on the serum biochemistry of animals. The supplementation of OMC and MMDA ameliorated the toxic effects, as observed in organ histology, and provided a notable reduction in residual AFs, FBs, and ZEN levels in the liver and kidneys. Moreover, the OMC supplementation was able to reduce the initiation of liver carcinogenesis without any hepatotoxic side effects. These findings demonstrate that the use of OMC and MMDA effectively mitigated the adverse effects of dietary AFs, FBs, and ZEN in piglets. Further studies should explore the long-term protective effects of the studied adsorbent supplementation to optimize mycotoxin management strategies in pig-farming operations.
A common way of exposing functionality in contemporary systems is by providing a Web-API based on the REST API architectural guidelines. To describe REST APIs, the industry standard is currently OpenAPI-specifications. Test generation and fuzzing methods targeting OpenAPI-described REST APIs have been a very active research area in recent years. An open research challenge is to aid users in better understanding their API, in addition to finding faults and to cover all the code. In this paper, we address this challenge by proposing a set of behavioural properties, common to REST APIs, which are used to generate examples of behaviours that these APIs exhibit. These examples can be used both (i) to further the understanding of the API and (ii) as a source of automatic test cases. Our evaluation shows that our approach can generate examples deemed relevant for understanding the system and for a source of test generation by practitioners. In addition, we show that basing test generation on behavioural properties provides tests that are less dependent on the state of the system, while at the same time yielding a similar code coverage as state-of-the-art methods in REST API fuzzing in a given time limit.
This research delves into the intricate dynamics of travelers’ decision-making processes, particularly their response to the media’s portrayal of environmental risks and the subsequent redirection of their travel choices toward medical destinations (MD). Employing a sophisticated research approach combining path analysis with moderation and multilinear logistic regression models, this study investigates the nuanced factors underlying travelers’ resilience to environmental risks and their propensity to opt for medical destinations. The results of the path analysis reveal a complex network of direct influences of factors from the PPM model (push, pull, and mooring) on choosing a medical destination in the sense that, before moderation, the only significant direct effect on the intention to choose medical destination (MD) was the pull factors. Through moderation, a significant effect of all three factors was achieved, while the direction of influence was changed in the case of push and pull factors. Furthermore, the multinomial logistic regression showed that the respondents prefer to go to a medical destination rather than a rural or urban one after the media emphasis on environmental risks. By integrating these analytical approaches and models, this research advances our understanding of how travelers navigate their choices amid environmental uncertainty. Furthermore, this research sheds light on the pivotal role that these traveler choices play in shaping the sustainability of medical destinations, offering essential insights for stakeholders, policymakers, and researchers navigating the evolving landscape of these destinations.
As the future electric power grid will be driven by distributed renewable energy sources, the deployment of grid-connected power converters will also grow to enable seamless grid and energy source interaction. To provide the reliable operation of these converters, the estimation of fundamental grid parameters is important. The most common estimation techniques are a phase-locked loops (PLL) and a frequency-locked loops (FLL). However, those techniques encounter challenges in conducting parameter estimation when the input signal is unbalanced due to DC-offset, harmonics, signal sags, and frequency and phase variations. This paper presents an enhanced FLL loop enriched with an additional loop for estimation and rejection of the DC-offset. Active and reactive power calculations in grid-connected microgrids by using the modified FLL loops with DC-offset rejection is a novel application introduced in this paper. Experimental verification has demonstrated that the enhanced FLL loop provides fast and reliable parameter estimation as well as stable and robust power calculations, even in the presence of a DC-offset.
The Brief Psychiatric Rating Scale (BPRS) is a useful tool for measuring the severity of psychopathological symptoms among patients with psychosis. Many studies, predominantly in Western countries, have investigated its factor structure. This study has the following aims: (a) to further explore the factor structure of the BPRS-Expanded version (BPRS-E, 24 items) among outpatients with psychotic disorders in Southeast European countries; (b) to confirm the identified model; and (c) to investigate the goodness-of-fit of the three competing BPRS-E factor models derived from previous studies. The exploratory factor analysis (EFA) produced a solution with 21 items grouped into five factors, thus supporting the existence of a fifth factor, i.e., Disorganization. A follow-up confirmatory factor analysis (CFA) revealed a 19-item model (with two items removed) that fit the data well. In addition, the stability of two out of three competing factor models was confirmed. Finally, the BPRS-E model with 5 factors developed in this cross-national study was found to include a greater number of items compared to competing models.
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